| Patents for C07D 489 - Heterocyclic compounds containing 4ah-8, 9 c- iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula: (2,334) |
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| 06/25/2009 | CA2709858A1 Process and compounds for the production of (+) opiates |
| 06/25/2009 | CA2709854A1 Process for the preparation of buprenorphine and derivatives of buprenorphine |
| 06/23/2009 | US7550592 Hydromorphone polymorphs |
| 06/18/2009 | WO2008121348A3 Peripheral opioid receptor antagonists and uses thereof |
| 06/18/2009 | US20090156820 Processes for the production of (+)- "NAL" morphinan compounds |
| 06/18/2009 | US20090156819 Processes for the preparation of normorphinan salts |
| 06/18/2009 | US20090156818 Process and compounds for the production of (+)opiates |
| 06/18/2009 | US20090156817 Process for the preparation of buprenorphine and derivatives for buprenorphine |
| 06/18/2009 | US20090156816 Sinomenine derivatives and processes for their synthesis |
| 06/18/2009 | US20090156815 Oripavine and thebaine, and C(3)-protected hydroxy derivatives of oripavine reacter with ethylchloroformate reacted with an ethyl chloroformate; intermediates for "nal" morphinan compounds such as naltrexone, naloxone, nalbuphene, nalmefene, and buprenorphine |
| 06/18/2009 | US20090156814 Transdermally Deliverable Opioid Prodrugs, Abuse-Resistant Compositions and Methods of Using Opioid Prodrugs |
| 06/04/2009 | WO2009070733A1 Peripheral phenolic opioid antagonist |
| 06/04/2009 | US20090143417 Methods of treating pain |
| 06/03/2009 | EP2064215A1 Transdermally deliverable buprenorphine prodrugs and abuse-resistant compositions thereof |
| 06/02/2009 | US7541364 Compounds of the above formula are useful as analgesics for treating pain; as immunomodulators, to modulate the behavioral effects of drugs of abuse and to modulate the development of tolerance and dependence of mu agonists. |
| 05/28/2009 | US20090137809 Demethylation of 14 hydroxy substituted alkaloid derivatives |
| 05/28/2009 | US20090137618 Pro-drugs for controlled release of biologically active compounds |
| 05/27/2009 | EP2062897A1 Demethylation of 14-hydroxy substituted alkaloid derivatives |
| 05/27/2009 | EP2062896A1 Demethylation of 14-hydroxy substituted alkaloid derivatives |
| 05/27/2009 | EP1244448B1 Novel methods for the treatment and prevention of ileus |
| 05/26/2009 | US7538118 6-aminomorphinane derivatives, method for production and use thereof |
| 05/26/2009 | CA2644881A1 Demethylation of 14-hydroxy substituted alkaloid derivatives |
| 05/26/2009 | CA2640316A1 Demethylation of 14-hydroxy substituted alkaloid derivatives |
| 05/20/2009 | CN101437516A Treatment of diseases using nalmefene and its analogs |
| 05/19/2009 | US7534888 Oxycodone polymorphs |
| 05/19/2009 | US7534799 Pyridomorphinans, thienomorphinans and use thereof |
| 04/30/2009 | WO2009009292A3 Crystalline forms of naltrexone methobromide |
| 04/30/2009 | WO2008138605A3 Method for producing n-methylnaltrexone bromide |
| 04/30/2009 | US20090111843 Therapeutic or Prophylactic Agent for Functional Bowel Disorder |
| 04/23/2009 | WO2006029167A3 Treatment of diseases using nalmefene and its analgos |
| 04/15/2009 | EP1794165B1 Preparation of opiate analgesics by reductive alkylation |
| 04/09/2009 | WO2009044883A1 Remedy for relieving skin troubles comprising morphinan derivative or pharmacologically acceptable acid addition salt thereof as the active ingredient |
| 04/09/2009 | WO2006034039A3 Substituted morphinans and methods of their use |
| 04/09/2009 | WO2005086960A3 Narcotic-nsaid ion pairs |
| 04/09/2009 | CA2702032A1 Skin property-improving therapeutic agent comprising a morphinan derivative or any of its pharmacologically permissible acid addition salts as an active ingredient |
| 04/07/2009 | US7514100 Controlled release hydrocodone formulations |
| 04/02/2009 | WO2009004491A3 Preparation of oxycodone |
| 03/26/2009 | US20090082383 Deuterium-enriched buprenorphine |
| 03/26/2009 | US20090082382 Deuterium-enriched naltrexone |
| 03/25/2009 | EP2039696A1 Process for the preparation of quaternary N-alkyl morphine or morphinane alkaloid derivatives |
| 03/25/2009 | CN101395159A Processes for preparing morphinan-6-one products with low levels of alpha, beta-unsaturated ketone compounds |
| 03/19/2009 | US20090076052 Deuterium-enriched nalmefene |
| 03/19/2009 | US20090076051 Deuterium-enriched methylnaltrexone |
| 03/19/2009 | US20090075822 Method of Altering the Alkaloid Composition in Poppy Plants |
| 03/17/2009 | US7504405 Mitotic kinesin inhibitors |
| 03/12/2009 | US20090069363 Therapeutic Agent for Constipation |
| 03/11/2009 | CN101384601A Novel 6-amino-morphinan derivatives, method of manufacturing them and their application as analgesics |
| 03/10/2009 | US7501434 Reduced gastrointestinal side effects of analgesic opioid therapy |
| 03/10/2009 | US7501433 Opioid and opioid-like compounds and uses thereof |
| 03/10/2009 | CA2332974C Morphine-6-glucuronide synthesis |
| 03/05/2009 | US20090062544 Crystals of Morphinan Derivative and Process for Producing the Same |
| 03/04/2009 | EP1380306B1 Remedies for restless leg syndrome |
| 02/24/2009 | US7495098 Dissolving opium in solvent, heating, cooling, adjusting pH with weak acid, filtering; solvent extraction; liquid chromatography |
| 02/19/2009 | WO2009023567A1 Quaternary opioid carboxamides |
| 02/19/2009 | WO2008144320A3 Opioid and methods of making and using the same |
| 02/19/2009 | US20090048447 Method for decreasing opioid metabolism |
| 02/19/2009 | CA2694497A1 Quaternary opioid carboxamides |
| 01/28/2009 | EP2019105A1 Process for the preparation of quaternary n-alkyl morphine or morphinane alkaloid derivatives |
| 01/28/2009 | CN101356177A The use of oripavine as a starting material for buprenorphine |
| 01/28/2009 | CN101356176A Therapeutic or prophylactic agent for functional bowel disorder |
| 01/28/2009 | CN101355943A Therapeutic agent for nausea and/or vomiting |
| 01/22/2009 | WO2009012005A1 Preparation of n-alkylated opiates by reductive amination |
| 01/22/2009 | CA2693436A1 Preparation of n-alkylated opiates by reductive amination |
| 01/19/2009 | CA2638195A1 Process for the preparation of quaternary n-alkyl morphin or morphinan alkaloid derivatives |
| 01/15/2009 | WO2009009292A2 Crystalline forms of naltrexone methobromide |
| 01/15/2009 | WO2008136865A9 (s)-n-stereoisomers of 7,8-saturated-4,5-epoxy-morphinanium analogs |
| 01/15/2009 | WO2008121352A3 Crystal forms of (r) -n-methylnaltrexone bromide and uses thereof |
| 01/15/2009 | US20090018154 Opioid and methods of making and using the same |
| 01/15/2009 | US20090017102 Enhancing transdermal delivery of opiod antagonists and agonistis using codrugs links to bupropion or hydroxybupropion |
| 01/14/2009 | CN101346384A Processes for reducing contaminating michael acceptor levels in oxycodone and other compositions |
| 01/08/2009 | WO2009003272A1 Methods for n-demethylation of morphine and tropane alkaloids |
| 01/08/2009 | WO2009003271A1 Conversion of thebaine to morphine derivatives |
| 01/08/2009 | WO2009003270A1 Methods for one-pot n-demethylation/n-acylation of morphine and tropane alkaloids |
| 01/08/2009 | US20090012110 Morphine compounds for pharmaceutical compositions |
| 01/08/2009 | CA2692433A1 Methods for n-demethylation of morphine and tropane alkaloids |
| 01/08/2009 | CA2692429A1 Conversion of thebaine to morphine derivatives |
| 01/08/2009 | CA2692426A1 Methods for one-pot n-demethylation/n-acylation of morphine and tropane alkaloids |
| 01/07/2009 | EP2010539A2 Stereoselective reduction of a morphinone |
| 01/07/2009 | CN101340911A Antitussive agent |
| 01/01/2009 | US20090005564 Methods for n-demethylation of morphine and tropane alkaloids |
| 01/01/2009 | US20090005563 Conversion of thebaine to morphine derivatives |
| 12/31/2008 | WO2009001764A1 Remedy or preventive for integration dysfunction syndrome |
| 12/31/2008 | EP2007762A2 Mono and di-substituted oxycodone compounds and compositions |
| 12/31/2008 | EP1732926B1 Mitotic kinesin inhibitors |
| 12/31/2008 | CA2691220A1 Remedy or preventive for integration dysfunction syndrome |
| 12/29/2008 | CA2636734A1 Metal coordinated compositions |
| 12/18/2008 | US20080312443 Preparation of oxycodone |
| 12/18/2008 | US20080312442 Process for Preparing Morphinan-6-One Products with Low Levels of Alpha, Beta-Unsaturated Ketone Compounds |
| 12/18/2008 | US20080312441 Use of Oripavine as a Starting Material For Buprenorphine |
| 12/17/2008 | EP2003134A2 Hydromorphinone and hydrocodeinone compositions and methods for their synthesis |
| 12/17/2008 | EP2001877A1 Method for extracting target alkaloid using an ionic liquid as extracting solvent |
| 12/16/2008 | US7465797 6-monoacetylmorphine derivatives useful in immunoassay |
| 12/11/2008 | WO2008045556A3 Novel synergistic opioid-cannabinoid codrug for pain management |
| 12/11/2008 | US20080306265 Preparation of oxycodone |
| 12/10/2008 | CN101317825A Controlled release hydrocodone formulations |
| 12/09/2008 | US7462713 Tricyclic compounds protein kinase inhibitors for enhancing the efficacy of anti-neoplastic agents and radiation therapy |
| 12/03/2008 | CN101314604A 7 alpha-substituted phenyl-6 alpha, alpha-endo-ethylidene(ethenylidene)-tetrahydrochysene paramorphine derivant or its salt, preparation method and application thereof |
| 12/03/2008 | CN100439373C Oxycodone-hydrochloride polymorhs |
| 11/27/2008 | WO2008144394A2 Fused-ring heterocycle opioids |
| 11/27/2008 | WO2008144320A2 Opioid and methods of making and using the same |