Patents
Sitemap › C07 - Organic chemistry › C07D - Heterocyclic compounds › C07D 489 - Heterocyclic compounds containing 4ah-8, 9 c- iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula:
Patents for C07D 489 - Heterocyclic compounds containing 4ah-8, 9 c- iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula: (2,334)
06/2010
06/10/2010WO2010065441A1 Process for preparing hydrocodone using a super acid
06/10/2010WO2010063292A1 Nalmefene hydrochloride dihydrate
06/10/2010US20100145051 N-methylnaltrexone zwitterion
06/10/2010CA2745410A1 Process for preparing hydrocodone using a super acid
06/10/2010CA2744932A1 Nalmefene hydrochloride dihydrate
06/09/2010EP2194059A2 Methods for making 3-O-protected morphinones and 3-O-protected morphinone dienol carboxylates
06/03/2010US20100137598 Process for Preparing Hydrocodone Using a Super Acid
06/02/2010EP2190819A1 Quaternary opioid carboxamides
05/2010
05/27/2010US20100130524 Therapeutic or prophylactic agent for dyskinesia
05/27/2010US20100130512 Fused-ring heterocycle opioids
05/26/2010EP2189460A1 Improved process for the preparation of 6-alpha-hydroxy-n-alkylated opiates
05/19/2010CN101033228B Method of preparing 14-hydroxy-7,8-dihydromorphone
05/18/2010US7718664 Anti-itching agent
05/13/2010US20100120814 Crystalline and Amorphous Forms of Naltrexone Hydrochloride
05/13/2010US20100120813 Peripheral opioid receptor antagonists and uses thereof
05/06/2010US20100113788 Process for the Preparation of 6-Alpha-Hydroxy-N-Alkylated Opiates
05/06/2010US20100113787 Preparation of Oxymorphone from Oripavine
05/06/2010US20100113497 Gaba conjugates and methods of use thereof
04/2010
04/29/2010US20100105911 (S)-N-methylnal trexone
04/28/2010EP2180000A1 Improved process for the preparation of 6-alpha-hydroxy-n-alkylated opiates
04/28/2010EP1421085B1 Process for the preparation of a 14-hydroxynormorphinone derivative
04/14/2010EP2173754A1 Conversion of thebaine to morphine derivatives
04/08/2010WO2010039851A1 Peripheral opioid receptor antagonists and uses thereof
04/08/2010WO2010039222A2 Processes for the selective amination of ketomorphinans
04/08/2010WO2010039221A1 Recycling process for increasing the yield of a grignard reaction in the preparation of opiate alkaloid derivatives
04/08/2010WO2010039220A1 Processes for the production of buprenorphine with reduced impurity formation
04/08/2010WO2010039217A1 Processes for the synthesis of opiate alkaloids with reduced impurity formation
04/08/2010WO2010039216A1 Processes for the alkylation of norbuprenorphine with reduced impurity formation
04/08/2010WO2010039214A1 Processes for increasing the yield of the hydrolysis of the 3-0-methyl and 17-n-nitrile group in the preparation of opiate alkaloid derivatives
04/08/2010WO2010039210A1 Processes for the hydrogenation of opiate alkaloid derivatives
04/08/2010WO2010039209A2 Processes for the synthesis of tertiary amines
04/08/2010CA2738761A1 Processes for the production of buprenorphine with reduced impurity formation
04/08/2010CA2738758A1 Processes for the alkylation of norbuprenorphine with reduced impurity formation
04/08/2010CA2738628A1 Processes for the selective amination of ketomorphinans
04/08/2010CA2738305A1 Processes for the synthesis of opiate alkaloids with reduced impurity formation
04/08/2010CA2738250A1 Processes for increasing the yield of the hydrolysis of the 3-0-methyl and 17-n-nitrile group in the preparation of opiate alkaloid derivatives
04/08/2010CA2738246A1 Processes for the synthesis of tertiary amines
04/08/2010CA2738089A1 Processes for the hydrogenation of opiate alkaloid derivatives
04/08/2010CA2738066A1 Recycling process for increasing the yield of a grignard reaction in the preparation of opiate alkaloid derivatives
04/07/2010EP2170898A1 Methods for n-demethylation of morphine and tropane alkaloids
04/07/2010EP2170897A1 Methods for one-pot n-demethylation/n-acylation of morphine and tropane alkaloids
04/06/2010US7692013 acidification; elution; cost efficiency
04/01/2010US20100081820 Processes for the alkylation of norbuprenorphine with reduced impurity formation
04/01/2010US20100081819 Processes for the synthesis of tertiary amines
04/01/2010US20100081818 Process for the Preparation of 6-Alpha-Hydroxy-N-Alkylated Opiates
04/01/2010US20100081817 Processes for the selective amination of ketomorphinans
04/01/2010US20100081816 Processes for synthesis of opiate alkaloid derivatives
04/01/2010US20100081815 Recycling process for increasing the yield of opiate alkaloid derivatives
04/01/2010US20100081814 Processes for increasing the yield of opiate alkaloid derivatives
04/01/2010US20100081813 Processes for the synthesis of opiates alkaloids with reduced impurity formation
03/2010
03/31/2010EP2168580A1 Remedy or preventive for integration dysfunction syndrome
03/31/2010EP2168579A1 Oral preparation comprising specific organic acid, and method for improvement in elution property and chemical stability of oral preparation
03/31/2010EP2167506A2 Method for producing n-methylnaltrexone bromide
03/31/2010EP2167505A1 Preparation of n-alkylated opiates by reductive amination
03/31/2010CN101686977A Therapeutic or prophylactic agent for dyskinesia
03/25/2010WO2010033890A1 Polymorphs of 6-beta-naltrexol
03/25/2010WO2010033442A1 Processes for the synthesis of five and six membered heterocyclic rings
03/25/2010US20100076007 Polymorphs of 6-Beta-Naltrexol
03/25/2010CA2737159A1 Processes for the synthesis of five and six membered heterocyclic rings
03/24/2010CN101678016A N-oxides of 4,5-epoxy-morphinanium analogs
03/23/2010US7683170 Methods for preparing Irinotecan
03/23/2010US7683072 Oxycodone hydrochloride having less than 25 ppm 14-hydroxycodeinone
03/18/2010US20100069639 Processes for the Synthesis of Five and Six Membered Heterocyclic Rings
03/17/2010EP1807433B1 Method for separation and purification of hydrocodone by preparative chromatography
03/09/2010US7674904 Synthesis of R-N-methylnaltrexone
03/09/2010US7674800 Process of salt formation and by-product inhibition; FDA Orange Book listed patent for tradename Oxycontin
03/09/2010US7674799 Oxycodone hydrochloride having less than 25 ppm 14-hydroxycodeinone
03/09/2010US7674798 Oxycodone hydrochloride having less than 25 ppm 14-hydroxycodeinone
03/09/2010CA2388395C Compound
03/02/2010US7671204 Oripavine and thebaine, and C(3)-protected hydroxy derivatives of oripavine reacter with ethylchloroformate reacted with an ethyl chloroformate; intermediates for "nal" morphinan compounds such as naltrexone, naloxone, nalbuphene, nalmefene, and buprenorphine
03/02/2010US7671203 Method and system for separation and purification of at least one narcotic alkaloid using reverse phase preparative chromatography
02/2010
02/25/2010US20100048905 Novel Opiate Reduction Utilizing Catalytic Hydrogen Transfer Reaction
02/25/2010US20100048602 Oligomer-Opioid Agonist Conjugates
02/24/2010EP2156837A1 Crystalline micropowder particles
02/24/2010CN101653411A Controlled release hydrocodone formulations
02/18/2010WO2010017573A1 PROCESS FOR MAKING MORPHINAN-6α-OLS
02/18/2010WO2009132313A3 Morphinan derivatives of organic and inorganic acids
02/18/2010WO2009092073A3 Amino acid and peptide prodrugs of opioid analgesics with reduced gi side-effects
02/18/2010US20100041888 Process for the Preparation of 6-Alpha-Hydroxy-N-Alkylated Opiates
02/17/2010EP2152715A1 Improved process for the preparation of 6-alpha-hydroxy-n-alkylated opiates
02/17/2010CN101652371A Improved method for making analgesics
02/17/2010CN101652370A Process for preparing oxycodone having reduced levels of 14-hydroxycodeinone
02/17/2010CN101652369A Process for reducing impurities in oxycodone base
02/11/2010WO2009092071A3 Amino acid and peptide pro-drugs of phenolic analgesics and uses thereof
02/11/2010US20100036128 PROCESS FOR MAKING MORPHINAN-6alpha-OLS
02/11/2010US20100035910 Process for the Preparation of Quaternary N-Alkyl Morphinan Alkaloid Salts
02/10/2010EP2151240A1 Therapeutic or prophylactic agent for dyskinesia
02/10/2010EP2150554A1 Solvent-free crystalline form of naltrexone
02/10/2010CN101646676A (s)-n-stereoisomers of 7,8-saturated-4,5-epoxy-morphinanium analogs
02/10/2010CN101646675A Process for the preparation of quaternary N-alkyl morphinan alkaloid salts
02/04/2010WO2010014229A1 Buprenorphine analogs
02/04/2010WO2010013044A1 Nalmefene and derivatives thereof for the treatment of skin disorders
02/04/2010CA2731939A1 Buprenorphine analogs
02/03/2010EP2148864A2 Fused-ring heterocycle opioids
02/03/2010CN100586434C Anti-itching agent
02/02/2010US7655671 Morphinan derivatives, the quaternary ammonium salts thereof substituted in position 14, method for production and use thereof
01/2010
01/28/2010US20100022774 Process useful in the preparation of morphinan antagonists
01/27/2010EP2147920A2 Process for the preparation of quaternary n-alkyl morphinan alkaloid salts
01/27/2010CN101636400A Processes for synthesizing quaternary 4,5-epoxy-morphinan analogs and isolating their n-stereoisomers
01/26/2010US7652025 Remedies for sepsis
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