| Patents for C07D 489 - Heterocyclic compounds containing 4ah-8, 9 c- iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula: (2,334) |
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| 06/09/2011 | US20110136846 Buprenorphine Analogs |
| 06/09/2011 | US20110136845 (+)-Morphinans as Antagonists of Toll-Like Receptor 9 and Therapeutic Uses Thereof |
| 06/08/2011 | EP2328900A1 PROCESS FOR MAKING MORPHINAN-6 alpha-OLS |
| 06/08/2011 | EP2328899A1 Processes for the synthesis of five and six membered heterocyclic rings |
| 06/08/2011 | CN102089311A Methods of synthesis of morphinans |
| 06/08/2011 | CN102089310A Process for the synthesis of N-demethylated morphinane compounds |
| 06/08/2011 | CN101314604B 7 alpha-substituted phenyl-6 alpha, alpha-endo-ethylidene(ethenylidene)-tetrahydrochysene paramorphine derivant or its salt, preparation method and application thereof |
| 06/08/2011 | CN101137658B Antipruritic agent for pruritus caused by multiple sclerosis |
| 06/07/2011 | US7956187 Method for decreasing opioid metabolism |
| 06/01/2011 | EP2326651A1 Buprenorphine analogs |
| 05/31/2011 | US7951817 Pyridomorphinans, pyridazinomorphinans and use thereof |
| 05/19/2011 | US20110118466 Process for preparing oxymorphone, naltrexone, and buprenorphine |
| 05/18/2011 | CN102066381A Nalmefene prodrugs |
| 05/17/2011 | US7943174 Controlled release hydrocodone formulations |
| 05/12/2011 | WO2011037854A3 Methods for producing hydrocodone, hydromorphone or a derivative thereof |
| 05/12/2011 | US20110112297 Morphinan derivatives and preparation methods thereof |
| 05/12/2011 | US20110112131 Opioid-Ketamine and Norketamine Codrug Combinations for Pain Management |
| 05/12/2011 | US20110112130 Opioid-Nornicotine Codrugs Combinations for Pain Management |
| 05/11/2011 | EP2319846A1 Process for preparing oxycodone hydrochloride having less than 25ppm 14-hydroxycodeinone |
| 05/11/2011 | EP2319845A1 3-Hydroxymorphinan derivatives |
| 05/10/2011 | US7939543 Method of reducing α, β unsaturated ketones in opioid compositions |
| 05/05/2011 | US20110105381 Prodrugs of Peripheral Phenolic Opioid Antagonists |
| 05/05/2011 | US20110100099 Preparation and use of (r),(r)-2,2'-bis-methylnaltrexone |
| 05/04/2011 | EP2316837A1 Process for preparing oxycodone hydrochloride having less than 25ppm 14-hydroxycodeinone |
| 05/04/2011 | CN102046631A An improved process for the preparation of morphinane analogues |
| 05/03/2011 | US7935821 Method for separation and purification of naltrexone by preparative chromatography |
| 05/03/2011 | US7935820 Methods for N-demethylation of morphine and tropane alkaloids |
| 04/28/2011 | WO2010144640A3 Reductive amination of 6-keto normorphinans by catalytic hydrogen transfer |
| 04/27/2011 | EP2314589A1 Process for preparing oxycodone hydrochloride having less than 25ppm 14-hydroxycodeinone |
| 04/27/2011 | CN1918168B Methods for making 3-o-protected morphinones and 3-o-protected morphinone dienol carboxylates |
| 04/27/2011 | CN102036993A Nalmefene di-ester prodrugs |
| 04/20/2011 | EP2311839A1 Oxycodone hydrochloride composition having less than 25 ppm 14-hydroxycodeinone |
| 04/20/2011 | EP1399161B1 Sustained-release analgesic compounds |
| 04/19/2011 | US7928234 Conversion of thebaine to morphine derivatives |
| 04/13/2011 | EP2307420A1 Nalmefene di-ester prodrugs |
| 04/12/2011 | US7923454 morphinan's such as 3-methoxy-17-allylmorphinan hydrobromide used for preventing or treating viral infections, septic shock, organ damage, neurological and cardiovascular disorders, neurodegenerative diseases and cancers |
| 04/12/2011 | US7923453 Methods of converting a patient's treatment regimen from intravenous administration of an opioid to oral co-administration of morphine and oxycodone using a dosing algorithm to provide analgesia |
| 04/12/2011 | CA2500118C N-substituted hydromorphones and the use thereof |
| 04/12/2011 | CA2484985C Microbial n- and o-demethylation of a thebaine derivative |
| 04/07/2011 | US20110082297 Process for the Preparation of Quaternary N-Alkyl Morphinan Alkaloid Salts |
| 04/06/2011 | EP2305683A1 Pharmaceutical dosage form comprising oxycodone hydrochloride having less than 25 ppm 14-hydroxycodeinone |
| 04/06/2011 | EP2305218A1 Controlled release hydrocodone formulations |
| 04/06/2011 | EP2303892A1 Methods of synthesis of morphinans |
| 04/06/2011 | CN102002049A Antigen and preparation method and application thereof |
| 03/31/2011 | WO2011037854A2 Methods for producing hydrocodone, hydromorphone or a derivative thereof |
| 03/30/2011 | EP2300479A1 Nalmefene hydrochloride dihydrate |
| 03/24/2011 | WO2011035276A2 Heterogeneous ruthenium metal catalyst for the production of hydrocodone, hydromorphone or a derivative thereof |
| 03/24/2011 | WO2011034747A1 Preparation of 10-keto morphinans by benzylic oxidation |
| 03/24/2011 | WO2011032214A1 A method for the n-demethylation of n-methyl heterocycles |
| 03/24/2011 | US20110071297 Methods for Producing Hydrocodone, Hydromorphone or a Derivative Thereof |
| 03/24/2011 | US20110071296 Preparation of 10-Keto Morphinans by Benzylic Oxidation |
| 03/24/2011 | US20110071016 Heterogeneous Ruthenium Metal Catalyst for the Production of Hydrocodone, Hydromorphone or a Derivative Thereof |
| 03/23/2011 | EP2297161A1 Processes for the preparation of 6- beta-hydroxy morphinan compounds |
| 03/23/2011 | EP2297160A1 Process for the synthesis of n-demethylated morphinane compounds |
| 03/22/2011 | US7910599 Method for treating eating disorders by selective extinction with transdermal naloxone |
| 03/17/2011 | WO2011031350A1 Compositions comprising enzyme-cleavable ketone-modified opioid prodrugs and optional inhibitors thereof |
| 03/17/2011 | US20110065743 Kappa opioid receptor ligands |
| 03/17/2011 | CA2773340A1 Compositions comprising enzyme-cleavable ketone-modified opioid prodrugs and optional inhibitors thereof |
| 03/16/2011 | EP2295043A1 Controlled release hydrocodone formulations |
| 03/16/2011 | EP2295042A1 Controlled release hydrocodone formulations |
| 03/15/2011 | US7906647 Heating an oxycodone base starting material having more than 100 ppm of 14-hydroxycodeinone and sodium hydrosulfite, sodium bisulfite, or sodium metabisulfite in an alcohol/water; isolating oxycodone base having less than 10 ppm of 14-hydroxycodeinone |
| 03/09/2011 | EP2291380A1 Nalmefene prodrugs |
| 03/09/2011 | EP1730151B1 Process for preparing oxycodone hydrochloride having less than 25 ppm 14-hydroxycodeinone |
| 03/03/2011 | US20110054175 System for fluorinating organic compounds |
| 03/03/2011 | US20110053971 Nalmefene di-ester prodrugs |
| 02/24/2011 | WO2011021029A1 Process for reducing the 6-keto group of a morphinan alkaloid to the 6-hydroxy group by hydrogenation |
| 02/24/2011 | US20110047653 Cultivars of the poppy papaver bracteatum that produce seed capsules and thebaine in the first growing season |
| 02/24/2011 | US20110046599 Multi-Day Delivery Of Biologically Active Substances |
| 02/23/2011 | EP2285780A1 Processes and compounds for the preparation of normorphinans |
| 02/17/2011 | US20110040072 Mono and di-substituted oxycodone compounds and compositions |
| 02/17/2011 | US20110038927 Controlled release hydrocodone formulations |
| 02/16/2011 | EP2283829A1 Controlled release hydrocodone formulations |
| 02/15/2011 | CA2457671C Process for the preparation of a 14-hydroxynormorphinone derivative |
| 02/10/2011 | US20110034502 Nalmefene prodrugs |
| 02/02/2011 | CN101965187A Crystalline micropowder particles |
| 01/26/2011 | CN101959892A Preparation and use of (R),(R)-2,2'-bis-methylnaltrexone |
| 01/26/2011 | CN101955484A Method for synthesizing naloxone or naltrexone |
| 01/25/2011 | US7875719 Process for reducing impurities in oxycodone base |
| 01/25/2011 | US7875718 Process for the synthesis of morphinane compounds and intermediates thereof |
| 01/25/2011 | US7875623 composition is treated with a thiol-containing compound under conditions sufficient to remove Michael acceptors such as 14-hydroxycodeinone |
| 01/20/2011 | WO2011009015A1 (+) - morphinans as antagonists of toll-like receptor 9 and therapeutic uses thereof |
| 01/20/2011 | WO2011008636A1 3-oxy-hydromorphone derivatives |
| 01/20/2011 | US20110015398 3-Oxy-Hydromorphone Derivatives |
| 01/20/2011 | US20110015219 (+)-Morphinans as Antagonists of Toll-Like Receptor 9 and Therapeutic Uses Thereof |
| 01/20/2011 | CA2768236A1 (+)-morphinans as antagonists of toll-like receptor 9 and therapeutic uses thereof |
| 01/19/2011 | CN101092397B Structure modified compound of sinomenine, and prepartion method |
| 01/18/2011 | US7872013 opiod and/or N-methylaspartic acid receptor modulators, used for the treatment and/or management of pain, neurodegenerative diseases, drug abuse and dependence, vision defects, or as muscle relaxants, antitussive and anxiolytic agents |
| 01/13/2011 | WO2011005452A1 Method for the enrichment of buprenorphine using chromatographic techniques |
| 01/13/2011 | US20110009634 Process for preparing oxymorphone |
| 01/13/2011 | US20110009633 Method for the Enrichment of Buprenorphine using Chromatographic Techniques |
| 01/11/2011 | CA2545052C Method for the catalytic production of hydrocodone and hydromorphone |
| 01/06/2011 | US20110002991 Phenylethanoic acid, phenylpropanoic acid and phenylpropenoic acid conjugates and prodrugs of hydrocodone, method of making and use thereof |
| 01/06/2011 | US20110002990 Benzoic acid, benzoic acid derivatives and heteroaryl carboxylic acid conjugates of hydrocodone, prodrugs, methods of making and use thereof |
| 01/06/2011 | US20110002985 Abuse resistant drugs, method of use and method of making |
| 01/05/2011 | EP2269587A1 Controlled release hydrocodone formulations |
| 12/29/2010 | EP2266959A1 8-carboxamido-substituted-2, 6-methano-3-benzazocines and 3-carboxamido-substituted morphanes as opioid receptor binding agents |
| 12/29/2010 | EP2152715B1 Improved process for the preparation of 6-alpha-hydroxy-n-alkylated opiates |
| 12/29/2010 | EP1893616B1 A synthetic route to 14-hydroxyl opiates through 1-halo-thebaine or analogs |
| 12/23/2010 | US20100324078 Crystalline Forms of Naltrexone Methobromide |
| 12/22/2010 | EP2264464A2 Immunoassays for buprenorphine and norbuprenorphine |