Patents for C07D 489 - Heterocyclic compounds containing 4ah-8, 9 c- iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula: (2,334) |
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01/14/2010 | WO2010006299A1 Analgesic agents |
01/14/2010 | CA2730111A1 Synthesis of metabolically stable agents for alcohol and drug abuse |
01/12/2010 | US7645880 N-methylnaltrexone bromide; reduces adverse side effects of morphine on the gastrointestinal tract |
01/06/2010 | EP2139897A1 Crystalline and amorphous forms of naltrexone hydrochloride |
12/30/2009 | EP2137190A1 Novel opiate reduction utilizing catalytic hydrogen transfer reaction |
12/30/2009 | EP2137182A1 Combination of a narcotic and a non-narcotic analgesic |
12/24/2009 | US20090318699 Methods of synthesis of morphinans |
12/23/2009 | WO2009155259A1 Processes for the preparation of 6- beta-hydroxy morphinan compounds |
12/23/2009 | WO2009154673A1 Methods of synthesis of morphinans |
12/23/2009 | WO2009154041A1 Method for producing morphine |
12/23/2009 | WO2009152776A1 Morphinan derivatives and their preparation method |
12/23/2009 | WO2009152577A1 Process for the synthesis of n-demethylated morphinane compounds |
12/23/2009 | EP2134718A2 Crystal forms of (r)-n-methylnaltrexone bromide and uses thereof |
12/23/2009 | CN101610770A 7,8-saturated-4,5-epoxy-morphinanium analogs |
12/23/2009 | CN101607963A Morphinan derivatives and preparation method thereof |
12/23/2009 | CA2728083A1 Processes for the preparation of 6- beta-hydroxy morphinan compounds |
12/23/2009 | CA2727944A1 Process for the synthesis of n-demethylated morphinane compounds |
12/23/2009 | CA2727837A1 Methods of synthesis of morphinans |
12/17/2009 | US20090312552 Process for the Preparation of 6-Beta Hydroxy Morphinan Compounds |
12/17/2009 | US20090312333 2-Oxo-1-Pyrrolidine Derivatives, Processes for Preparing Them and Their Uses |
12/03/2009 | WO2009146288A1 Processes and compounds for the preparation of normorphinans |
12/03/2009 | WO2009122436A3 An improved process for the preparation of morphinane analogues |
12/03/2009 | US20090299069 Processes and Compounds for the Preparation of Normorphinans |
12/03/2009 | CA2726220A1 Processes and compounds for the preparation of normorphinans |
12/01/2009 | US7625918 pure physical form of hydrocodone bitartrate; analgesic agents |
11/25/2009 | EP2121699A1 Process for preparing oxycodone having reduced levels of 14-hydroxycodeinone |
11/17/2009 | US7619088 Demethylation of 14-hydroxy substituted alkaloid derivatives |
11/17/2009 | US7619087 Method of preparation of oxycodone |
11/11/2009 | EP1994034B1 Processes for preparing morphinan-6-one products with low levels of alpha, beta-unsaturated ketone compounds |
11/03/2009 | CA2442423C Therapeutic drug for psychoneurotic disorders |
10/29/2009 | WO2009132313A2 Morphinan derivatives of organic and inorganic acids |
10/29/2009 | WO2009130272A1 Nalmefene prodrugs |
10/29/2009 | WO2009130270A1 Nalmefene di-ester prodrugs |
10/29/2009 | CA2722246A1 Nalmefene prodrugs |
10/29/2009 | CA2722243A1 Nalmefene di-ester prodrugs |
10/22/2009 | WO2009129508A1 Soluble epoxide hydrolase inhibitors |
10/15/2009 | US20090258948 Pharmaceutical salts |
10/15/2009 | US20090258880 Substituted Tetrahydropyrrolopyrazine Compounds and the Use Thereof in Pharmaceutical Compositions |
10/15/2009 | US20090258864 Pyrimidine-2-amine compounds and their use as inhibitors of jak kinases |
10/08/2009 | WO2009122436A2 An improved process for the preparation of morphinane analogues |
10/08/2009 | CA2720034A1 An improved process for the preparation of morphinane analogues |
10/01/2009 | US20090247562 Large substituent, non-phenolic opioids and methods of use thereof |
09/30/2009 | EP1562953B1 Process for the preparation of quaternary n-alkyl morphinan alkaloid salts |
09/30/2009 | EP1554290B1 Analogs and prodrugs of buprenorphine |
09/24/2009 | US20090239892 Pyridomorphinans, pyridazinomorphinans and use thereof |
09/23/2009 | EP2102213A1 Improved method for making analgesics |
09/23/2009 | EP2101774A2 7,8-saturated-4,5-epoxy-morphinanium analogs |
09/23/2009 | EP2101773A2 (r)-n-stereoisomers of 7,8-saturated-4,5-epoxy-morphinanium analogs |
09/23/2009 | CN101541808A Improved process for the preparation of 6-alpha-hydroxy-N-alkylated opiates |
09/16/2009 | EP2099456A2 N-oxides of 4,5-epoxy-morphinanium analogs |
09/11/2009 | WO2009111162A1 Process for the preparation of 3-hydroxymorphinan derivatives |
09/11/2009 | CA2716944A1 Process for the preparation of 3-hydroxymorphinan derivatives |
09/10/2009 | US20090227796 Papaver Somniferum Strain With High Concentration Of Thebaine |
09/10/2009 | US20090227615 Oxycodone hydrochloride having less than 25 ppm 14-hydroxycodeinone |
09/09/2009 | EP2097418A1 Processes for synthesizing quaternary 4,5-epoxy-morphinan analogs and isolating their n-stereoisomers |
09/09/2009 | EP1664061A4 Process for the synthesis of morphinane compounds and intermediates thereof |
09/09/2009 | CN100537573C Remedies or preventives for urinary frequency or urinary incontinence and morphinan derivatives having nitrogen-containing heterocyclic group |
09/03/2009 | US20090221766 Stereoselective reduction of a morphinone |
09/02/2009 | EP1981891B1 The use of oripavine as a starting material for buprenorphine |
09/01/2009 | CA2452432C Active ingredient combination for the pharmacological therapy of nicotine dependence |
08/27/2009 | WO2008121348A8 Peripheral opioid receptor antagonists and uses thereof |
08/25/2009 | CA2430281C Use of weak opioids and mixed opioid agonists/antagonists for treatment of urinary incontinence |
08/20/2009 | US20090209570 6-Aminomorphinane Derivatives, Method for the Production and Use Thereof |
08/20/2009 | US20090209569 Selective opioid compounds |
08/20/2009 | US20090208413 Registry Method and Control System for Dea Schedule II-V Medicines |
08/20/2009 | CA2714331A1 Selective opioid compounds |
08/13/2009 | WO2009100014A1 System for fluorinating organic compounds |
08/13/2009 | WO2009099411A1 Preparation and use of (r),(r)-2,2'-bis-methylnaltrexone |
08/13/2009 | WO2009099410A1 Preparation and use of (r)-8-keto-methylnaltrexone |
08/13/2009 | US20090203723 6,7-unsaturated-7-carbamoyl substituted morphinan derivative |
08/13/2009 | US20090202629 Controlled release hydrocodone formulations |
08/13/2009 | CA2713568A1 Preparation and use of (r),(r)-2,2'-bis-methylnaltrexone |
08/06/2009 | US20090197905 Quaternary opioid carboxamides |
07/30/2009 | WO2009092912A1 Method for the preparation of morphine compounds |
07/30/2009 | US20090192095 Amino acid and peptide prodrugs of opioid analgesics with reduced gi side-effects |
07/30/2009 | CA2705251A1 Method for the preparation of morphine compounds |
07/29/2009 | CN101492451A 8alpha substituted aryl-4,5-epoxy morphinan derivative or its salt, preparation method and application thereof |
07/29/2009 | CN100518827C Controlled release hydrocodone formulations |
07/23/2009 | WO2009092073A2 Amino acid and peptide prodrugs of opioid analgesics with reduced gi side-effects |
07/23/2009 | WO2009092071A2 Amino acid and peptide pro-drugs of phenolic analgesics and uses thereof |
07/23/2009 | US20090186832 Amino acid peptide pro-drugs of phenolic analgesics and uses thereof |
07/21/2009 | CA2470809C 6-amino-morphinan derivatives, method of manufacturing them and their application |
07/16/2009 | WO2008144394A3 Fused-ring heterocycle opioids |
07/09/2009 | US20090176818 Antitussive Agent |
07/08/2009 | EP2076131A1 Process for preparing oxymorphone, naltrexone, and buprenorphine |
07/02/2009 | US20090171082 Mitotic kinesin inhibitors |
07/02/2009 | US20090170888 Antipruritic Agent for Pruritus Caused by Multiple Sclerosis |
07/02/2009 | US20090169508 Opioid and opioid-like compounds and uses thereof |
07/01/2009 | EP2073636A1 Process for preparing oxymorphone |
06/25/2009 | WO2009079013A1 Processes for the production of (+)-'nal' morphinan compounds |
06/25/2009 | WO2009078990A1 N-demethylation of n-methyl morphinans |
06/25/2009 | WO2009078989A1 Processes for the preparation of normorphinan salts |
06/25/2009 | WO2009078988A1 Sinomenine derivatives and processes for their synthesis |
06/25/2009 | WO2009078987A1 Process and compounds for the production of (+) opiates |
06/25/2009 | WO2009078986A1 Process for the preparation of buprenorphine and derivatives of buprenorphine |
06/25/2009 | US20090163717 Demethylation of 14-hydroxy substituted alkaloid derivatives |
06/25/2009 | CA2709886A1 Processes for the production of (+)-"nal" morphinan compounds |
06/25/2009 | CA2709882A1 N-demethylation of n-methyl morphinans |
06/25/2009 | CA2709872A1 Processes for the preparation of normorphinan salts |
06/25/2009 | CA2709862A1 Sinomenine derivatives and processes for their synthesis |