Patents
Patents for C07D 489 - Heterocyclic compounds containing 4ah-8, 9 c- iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula: (2,334)
01/2010
01/14/2010WO2010006299A1 Analgesic agents
01/14/2010CA2730111A1 Synthesis of metabolically stable agents for alcohol and drug abuse
01/12/2010US7645880 N-methylnaltrexone bromide; reduces adverse side effects of morphine on the gastrointestinal tract
01/06/2010EP2139897A1 Crystalline and amorphous forms of naltrexone hydrochloride
12/2009
12/30/2009EP2137190A1 Novel opiate reduction utilizing catalytic hydrogen transfer reaction
12/30/2009EP2137182A1 Combination of a narcotic and a non-narcotic analgesic
12/24/2009US20090318699 Methods of synthesis of morphinans
12/23/2009WO2009155259A1 Processes for the preparation of 6- beta-hydroxy morphinan compounds
12/23/2009WO2009154673A1 Methods of synthesis of morphinans
12/23/2009WO2009154041A1 Method for producing morphine
12/23/2009WO2009152776A1 Morphinan derivatives and their preparation method
12/23/2009WO2009152577A1 Process for the synthesis of n-demethylated morphinane compounds
12/23/2009EP2134718A2 Crystal forms of (r)-n-methylnaltrexone bromide and uses thereof
12/23/2009CN101610770A 7,8-saturated-4,5-epoxy-morphinanium analogs
12/23/2009CN101607963A Morphinan derivatives and preparation method thereof
12/23/2009CA2728083A1 Processes for the preparation of 6- beta-hydroxy morphinan compounds
12/23/2009CA2727944A1 Process for the synthesis of n-demethylated morphinane compounds
12/23/2009CA2727837A1 Methods of synthesis of morphinans
12/17/2009US20090312552 Process for the Preparation of 6-Beta Hydroxy Morphinan Compounds
12/17/2009US20090312333 2-Oxo-1-Pyrrolidine Derivatives, Processes for Preparing Them and Their Uses
12/03/2009WO2009146288A1 Processes and compounds for the preparation of normorphinans
12/03/2009WO2009122436A3 An improved process for the preparation of morphinane analogues
12/03/2009US20090299069 Processes and Compounds for the Preparation of Normorphinans
12/03/2009CA2726220A1 Processes and compounds for the preparation of normorphinans
12/01/2009US7625918 pure physical form of hydrocodone bitartrate; analgesic agents
11/2009
11/25/2009EP2121699A1 Process for preparing oxycodone having reduced levels of 14-hydroxycodeinone
11/17/2009US7619088 Demethylation of 14-hydroxy substituted alkaloid derivatives
11/17/2009US7619087 Method of preparation of oxycodone
11/11/2009EP1994034B1 Processes for preparing morphinan-6-one products with low levels of alpha, beta-unsaturated ketone compounds
11/03/2009CA2442423C Therapeutic drug for psychoneurotic disorders
10/2009
10/29/2009WO2009132313A2 Morphinan derivatives of organic and inorganic acids
10/29/2009WO2009130272A1 Nalmefene prodrugs
10/29/2009WO2009130270A1 Nalmefene di-ester prodrugs
10/29/2009CA2722246A1 Nalmefene prodrugs
10/29/2009CA2722243A1 Nalmefene di-ester prodrugs
10/22/2009WO2009129508A1 Soluble epoxide hydrolase inhibitors
10/15/2009US20090258948 Pharmaceutical salts
10/15/2009US20090258880 Substituted Tetrahydropyrrolopyrazine Compounds and the Use Thereof in Pharmaceutical Compositions
10/15/2009US20090258864 Pyrimidine-2-amine compounds and their use as inhibitors of jak kinases
10/08/2009WO2009122436A2 An improved process for the preparation of morphinane analogues
10/08/2009CA2720034A1 An improved process for the preparation of morphinane analogues
10/01/2009US20090247562 Large substituent, non-phenolic opioids and methods of use thereof
09/2009
09/30/2009EP1562953B1 Process for the preparation of quaternary n-alkyl morphinan alkaloid salts
09/30/2009EP1554290B1 Analogs and prodrugs of buprenorphine
09/24/2009US20090239892 Pyridomorphinans, pyridazinomorphinans and use thereof
09/23/2009EP2102213A1 Improved method for making analgesics
09/23/2009EP2101774A2 7,8-saturated-4,5-epoxy-morphinanium analogs
09/23/2009EP2101773A2 (r)-n-stereoisomers of 7,8-saturated-4,5-epoxy-morphinanium analogs
09/23/2009CN101541808A Improved process for the preparation of 6-alpha-hydroxy-N-alkylated opiates
09/16/2009EP2099456A2 N-oxides of 4,5-epoxy-morphinanium analogs
09/11/2009WO2009111162A1 Process for the preparation of 3-hydroxymorphinan derivatives
09/11/2009CA2716944A1 Process for the preparation of 3-hydroxymorphinan derivatives
09/10/2009US20090227796 Papaver Somniferum Strain With High Concentration Of Thebaine
09/10/2009US20090227615 Oxycodone hydrochloride having less than 25 ppm 14-hydroxycodeinone
09/09/2009EP2097418A1 Processes for synthesizing quaternary 4,5-epoxy-morphinan analogs and isolating their n-stereoisomers
09/09/2009EP1664061A4 Process for the synthesis of morphinane compounds and intermediates thereof
09/09/2009CN100537573C Remedies or preventives for urinary frequency or urinary incontinence and morphinan derivatives having nitrogen-containing heterocyclic group
09/03/2009US20090221766 Stereoselective reduction of a morphinone
09/02/2009EP1981891B1 The use of oripavine as a starting material for buprenorphine
09/01/2009CA2452432C Active ingredient combination for the pharmacological therapy of nicotine dependence
08/2009
08/27/2009WO2008121348A8 Peripheral opioid receptor antagonists and uses thereof
08/25/2009CA2430281C Use of weak opioids and mixed opioid agonists/antagonists for treatment of urinary incontinence
08/20/2009US20090209570 6-Aminomorphinane Derivatives, Method for the Production and Use Thereof
08/20/2009US20090209569 Selective opioid compounds
08/20/2009US20090208413 Registry Method and Control System for Dea Schedule II-V Medicines
08/20/2009CA2714331A1 Selective opioid compounds
08/13/2009WO2009100014A1 System for fluorinating organic compounds
08/13/2009WO2009099411A1 Preparation and use of (r),(r)-2,2'-bis-methylnaltrexone
08/13/2009WO2009099410A1 Preparation and use of (r)-8-keto-methylnaltrexone
08/13/2009US20090203723 6,7-unsaturated-7-carbamoyl substituted morphinan derivative
08/13/2009US20090202629 Controlled release hydrocodone formulations
08/13/2009CA2713568A1 Preparation and use of (r),(r)-2,2'-bis-methylnaltrexone
08/06/2009US20090197905 Quaternary opioid carboxamides
07/2009
07/30/2009WO2009092912A1 Method for the preparation of morphine compounds
07/30/2009US20090192095 Amino acid and peptide prodrugs of opioid analgesics with reduced gi side-effects
07/30/2009CA2705251A1 Method for the preparation of morphine compounds
07/29/2009CN101492451A 8alpha substituted aryl-4,5-epoxy morphinan derivative or its salt, preparation method and application thereof
07/29/2009CN100518827C Controlled release hydrocodone formulations
07/23/2009WO2009092073A2 Amino acid and peptide prodrugs of opioid analgesics with reduced gi side-effects
07/23/2009WO2009092071A2 Amino acid and peptide pro-drugs of phenolic analgesics and uses thereof
07/23/2009US20090186832 Amino acid peptide pro-drugs of phenolic analgesics and uses thereof
07/21/2009CA2470809C 6-amino-morphinan derivatives, method of manufacturing them and their application
07/16/2009WO2008144394A3 Fused-ring heterocycle opioids
07/09/2009US20090176818 Antitussive Agent
07/08/2009EP2076131A1 Process for preparing oxymorphone, naltrexone, and buprenorphine
07/02/2009US20090171082 Mitotic kinesin inhibitors
07/02/2009US20090170888 Antipruritic Agent for Pruritus Caused by Multiple Sclerosis
07/02/2009US20090169508 Opioid and opioid-like compounds and uses thereof
07/01/2009EP2073636A1 Process for preparing oxymorphone
06/2009
06/25/2009WO2009079013A1 Processes for the production of (+)-'nal' morphinan compounds
06/25/2009WO2009078990A1 N-demethylation of n-methyl morphinans
06/25/2009WO2009078989A1 Processes for the preparation of normorphinan salts
06/25/2009WO2009078988A1 Sinomenine derivatives and processes for their synthesis
06/25/2009WO2009078987A1 Process and compounds for the production of (+) opiates
06/25/2009WO2009078986A1 Process for the preparation of buprenorphine and derivatives of buprenorphine
06/25/2009US20090163717 Demethylation of 14-hydroxy substituted alkaloid derivatives
06/25/2009CA2709886A1 Processes for the production of (+)-"nal" morphinan compounds
06/25/2009CA2709882A1 N-demethylation of n-methyl morphinans
06/25/2009CA2709872A1 Processes for the preparation of normorphinan salts
06/25/2009CA2709862A1 Sinomenine derivatives and processes for their synthesis
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