| Patents for C07D 489 - Heterocyclic compounds containing 4ah-8, 9 c- iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula: (2,334) |
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| 03/29/1994 | US5298622 Spiroindane opiate analogs |
| 03/22/1994 | WO1994006426A1 Methods for identifying and using low/non-addictive opioid analgesics |
| 03/22/1994 | CA2145207A1 Methods for identifying and using low/non-addictive opioid analgesics |
| 01/20/1994 | WO1994001102A1 Aminimide-containing molecules and materials as molecular recognition agents |
| 01/20/1994 | CA2139349A1 Aminimide-containing molecules and materials as molecular recognition agents |
| 01/12/1994 | EP0577847A1 Morphinan derivative and medicinal use |
| 01/06/1994 | WO1994000509A1 Oxazolone derived materials |
| 01/06/1994 | CA2139350A1 Oxazolone derived materials |
| 11/09/1993 | US5260441 Fluorescence polarization process for detecting unauthorized consumption of morphine |
| 11/02/1993 | US5258512 Immunoassay for opiate alkaloids and their metabolites; tracers, immunogens and antibodies |
| 10/28/1993 | WO1993021188A1 Delta opioid receptor-selective benzylidene-substituted morphinans for the treatment of alcohol abuse |
| 10/14/1993 | WO1993020079A1 Novel opiate derivatives and protein and polypeptide opiate derivative conjugates and labels |
| 10/14/1993 | CA2132342A1 Novel opiate derivatives and protein and polypeptide opiate derivative conjugates and labels |
| 09/28/1993 | CA1322523C Central nervous system injury treatment with opiate- receptor antagonists |
| 09/01/1993 | EP0557385A1 Topical compositions for transdermal delivery of produg derivatives of morphine |
| 08/31/1993 | US5240933 14-hydroxy-n-(2-methoxyethyl)-7,8-dihydromorphine and -norisomorphine, processes for the preparation thereof and the use thereof as pharmaceutical compositions |
| 08/03/1993 | US5232926 Morphinane-skeletoned hydrazone derivatives |
| 07/24/1993 | WO1993015081A1 Morphinan derivative and medicinal use |
| 07/06/1993 | US5225417 Analgesics |
| 06/24/1993 | WO1993011761A1 Aryl-triflates and related compounds |
| 06/24/1993 | CA2126242A1 Aryl-triflates and related compounds |
| 06/15/1993 | US5219861 6 β-Thiomorphine derivatives |
| 05/12/1993 | EP0540757A1 Water-based recording ink |
| 05/04/1993 | US5208338 Compounds for medical diagnosis |
| 04/06/1993 | CA1315689C Quarternary derivatives of noroxymorphone which relieve nausea and emesis |
| 03/31/1993 | EP0534423A1 14-Hydroxy-N-(2-methoxyethyl)-7,8-dihydromorphine and -norisomorphine, process for their preparation and their use as medicines |
| 03/28/1993 | CA2079153A1 14-hydroxy-n-(2-methoxyethyl)-7, 8-dihydromorphine and - norisomorphine, processes for the preparation thereof and the use thereof as pharmaceutical compositions |
| 03/02/1993 | US5190947 Analgesics |
| 02/23/1993 | CA1313868C Orally active nonaddicting analgesics |
| 02/18/1993 | WO1993003051A1 A process for making morphine-6-glucuronide or substituted morphine-6-glucuronide |
| 12/23/1992 | WO1992022330A1 RADIOLABELED N-SUBSTITUTED-6-3,14-DIHYDROXY-4,5 αEPOXYMORPHINANS, THEIR INTERMEDIATES, METHODS OF PREPARATION AND USE |
| 11/26/1992 | WO1992020749A1 Water-based recording ink |
| 09/30/1992 | EP0496830A4 Total synthesis of northebaine, normorphine, noroxymorphone enantiomers and derivatives via n-nor intermediates |
| 08/20/1992 | WO1992013534A1 Pharmaceutical composition and use |
| 08/05/1992 | EP0496830A1 Total synthesis of northebaine, normorphine, noroxymorphone enantiomers and derivatives via n-nor intermediates |
| 07/14/1992 | CA1305056C Method and compositions for reducing neurotoxic injury |
| 05/29/1992 | WO1992008459A1 Topical compositions for transdermal delivery of produg derivatives of morphine |
| 05/27/1992 | EP0486671A1 Orally active nonaddicting analgesics |
| 05/19/1992 | CA1301150C Substituted benzoate ester prodrug derivatives of nalbuphine, intermediates thereto, and processes |
| 05/12/1992 | US5112975 Preparation of noroxymorphone from morphine |
| 04/02/1992 | WO1991018606A3 Orally active nonaddicting analgesics |
| 02/26/1992 | EP0472501A2 Codeinsalt of a substituted carbonacid, process of its preparation, its use and pharmaceutical preparations |
| 02/24/1992 | CA2049649A1 Codeine salt of a substituted carboxylic acid, processes for the preparation thereof, its use and pharmaceutical compositions |
| 02/19/1992 | EP0471525A1 Use of a pure narcotic antagonist, e.g. nalmefene, naltrexone, naloxone or diprenorphine, in the treatment of mast cell disease |
| 02/04/1992 | US5086058 Repetitive administration prior to drinking; opiate antagonist |
| 01/02/1992 | EP0261148B1 Orally active nonaddicting analgesics |
| 12/10/1991 | US5071985 Demethylation with sulfonic acid derivative in the presence of a sulfide |
| 12/08/1991 | WO1991018606A2 Orally active nonaddicting analgesics |
| 12/08/1991 | CA2064465A1 Orally active nonaddicting analgesics |
| 12/05/1991 | WO1991018605A1 Method for treating alcoholism with nalmefene |
| 11/21/1991 | EP0456833A1 Immunosuppressant and process for preparing the same |
| 10/15/1991 | US5057322 Method of treating mast cell disease |
| 10/09/1991 | EP0451009A2 Pharmaceutical composition comprising opiate antagonists for the treatment of emotional numbness |
| 09/23/1991 | CA2038539A1 Method for treating emotional numbness |
| 08/21/1991 | EP0442769A2 Compounds destined for encapsulation in erythrocytes, new derivatives of naloxone and naltrexone |
| 08/06/1991 | CA1287301C Method and composition for blocking antigen-induced allergic responses |
| 07/20/1991 | CA2034552A1 Compounds used for the encapsulation into erythrocytes - new naloxone and naltrexone derivatives |
| 07/02/1991 | US5028612 Method for treating emotional numbness |
| 05/29/1991 | WO1991007966A1 Immunosuppressant and process for preparing the same |
| 04/17/1991 | WO1991005768A1 Total synthesis of northebaine, normorphine, noroxymorphone enantiomers and derivatives via n-nor intermediates |
| 03/27/1991 | EP0418591A2 (+)-Isomers of endoetheno/endoethano-epoxymorphinan derivatives as antitussive agents |
| 02/27/1991 | EP0413709A1 Fatty amino acids, and homo- and hetero-oligomers and conjugates thereof |
| 02/05/1991 | US4990617 N-oxide prodrug derivatives of 3-hydroxy morphinans and partial morphinans and derivatives |
| 01/23/1991 | EP0409392A2 Compositions and method for treatment of mast cell-mediated dermatologic disorders using nalmefene |
| 01/22/1991 | US4987136 Opioid antagonists |
| 09/12/1990 | EP0103636B1 Use of opium antagonists for the manufacture of medicaments for controlling gastrointestinal dysmotility |
| 07/11/1990 | EP0377272A2 Use of nalmefene or naltrexone in the manufacture of a medicament for the treatment of inflammation in an arthritic disease or associated inflammatory diseases |
| 07/04/1990 | EP0154639B1 Pharmaceutical compositions having appetite reducing activity and a process for their preparation |
| 07/03/1990 | US4939264 Immunoassay for opiate alkaloids and their metabolites; tracers, immunogens and antibodies |
| 06/27/1990 | EP0374919A1 Morphine derivative |
| 06/21/1990 | CA2006311A1 Morphine derivative |
| 06/20/1990 | EP0373744A2 Use of nalmefene or naltrexone in the treatment of autoimmune diseases |
| 06/12/1990 | CA1270253A1 R(-)-10,11-alkylenedioxy-n-alkylnorapomorphine |
| 05/15/1990 | US4925848 Derivative of codeine useful as an agonist and process for the preparation of it |
| 05/09/1990 | EP0367533A2 Method of treatment for interstitial cystitis |
| 05/08/1990 | US4923875 Method for treatment of mast cell-mediated dermatologic disorders |
| 03/21/1990 | EP0359647A1 Process for the preparation of morphinane derivatives |
| 03/13/1990 | US4908135 Derived from 1,4,7,10-tetraoxa-2-alkenylcyclodecane, 1,4,7, 10,13-pentaoxa-2-alkenylcyclodecane, or 1,4,7,10,13,16-hexaoxa-2-alkenylcyclooctadecane; for separation of secondary amines from tertiary amines |
| 02/13/1990 | US4900845 Moiety for selective separation |
| 12/26/1989 | US4889860 Oximes of oxymorphone, naltrexone and naloxone as potent, selective opioid receptor agonists and antagonists |
| 11/02/1989 | WO1989010348A1 Fatty amino acids, and homo- and hetero-oligomers and conjugates thereof |
| 10/31/1989 | US4877791 Method of treatment for interestitial cystitis |
| 09/05/1989 | US4863928 Method of treatment for arthritic and inflammatory diseases |
| 08/22/1989 | CA1258674A1 Opiate agonists and antagonists |
| 08/15/1989 | US4857533 Method of treatment for autoimmune diseases |
| 07/19/1989 | EP0324212A1 Glucuronic acid derivatives of opioid antagonists |
| 03/28/1989 | US4816586 Delta opioid receptor antagonists |
| 02/21/1989 | US4806556 Gastrointestinal disorders with side effect reduction of central nervous system |
| 02/21/1989 | US4806543 Administering enantiomer of analgesic opiod agonist or antagonist compound |
| 02/09/1989 | WO1989000995A1 Delta opioid receptor antagonists |
| 02/07/1989 | US4803208 14-hydroxydihydromorphinone or their hydrazones or azines |
| 01/03/1989 | US4795813 Noroxymorphone |
| 12/21/1988 | EP0295783A2 A derivative of codeine |
| 12/15/1988 | WO1988009603A2 Central nervous system injury treatment with opiate-receptor antagonists |
| 11/15/1988 | CA1244825A1 Process for the dealkylation of alkaloids and intermediates |
| 10/04/1988 | US4775759 Synthesis and utilization of 17-methyl and 17-cyclopropylmethyl-3,14-dihydroxy-4,5α-epoxy 6β-fluoromorphinans (foxy and cyclofoxy) as (18F)-labeled opioid ligands for position emission transaxial tomography (PETT) |
| 09/20/1988 | US4772695 Process for the preparation of vinyl carbamates |
| 08/24/1988 | EP0279557A1 Moiety of selective separation |
| 08/16/1988 | US4764615 Process for the preparation of codeine from morphine |
| 07/26/1988 | US4760069 Oximes of oxymorphone, naltrexone and naloxone as potent, selective opioid receptor agonists and antagonists |