Patents
Sitemap › C07 - Organic chemistry › C07D - Heterocyclic compounds › C07D 489 - Heterocyclic compounds containing 4ah-8, 9 c- iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula:
Patents for C07D 489 - Heterocyclic compounds containing 4ah-8, 9 c- iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula: (2,334)
05/2014
05/27/2014US8735420 Polymorphic forms of naltrexone
05/22/2014US20140142132 Peripheral opioid receptor antagonists and uses thereof
05/20/2014US8729266 Preparation of N-alkylated opiates by reductive amination
05/20/2014CA2646313C Stereoselective reduction of a morphinone
05/20/2014CA2630703C Processes for reducing contaminating michael acceptor levels in oxycodone and other compositions
05/15/2014WO2012058695A3 Compositions of (-)-17-(cyclobutylmethyl) morphinan-3, 14-diol
05/14/2014EP2730578A1 Preparation and use of (r),(r)-2,2'-bis-methylnal trexone
05/14/2014EP2729469A1 Orvinol and thevinol derivatives useful in the treatment of drug and alcohol abuse
05/08/2014WO2014070745A1 Solid salt form of alpha-6-mpeg6-o-hydroxycodone as opioid agonists and uses thereof
05/06/2014US8716278 Abuse deterrent and anti-dose dumping pharmaceutical salts useful for the treatment of attention deficit/hyperactivity disorder
05/06/2014US8715721 Controlled release hydrocodone
04/2014
04/29/2014US8710226 Process for the preparation of morphinane analogues
04/29/2014US8709431 Enediyne compounds, conjugates thereof, and uses and methods therefor
04/29/2014CA2597350C Process for purifying noroxymorphone compounds
04/24/2014US20140112981 Controlled release hydrocodone formulations
04/22/2014US8703950 Low ABUK oxycodone, its salts and methods of making same
04/22/2014US8703949 Tandem process for preparing N-alkyl morphinans
04/16/2014CN101805343B Chemically modified small molecules
04/09/2014EP2714695A1 Crystalline, anhydrous forms of oxymorphone hydrochloride
04/08/2014US8691989 Methods of synthesis of morphinans
04/02/2014CN103690540A Controlled release hydrocodone formulations
04/01/2014US8685996 Methods for making 3-O-protected morphinones and 3-O-protected morphinone dienol carboxylates
03/2014
03/27/2014US20140088132 Crystalline, anhydrous forms of oxymorphone hydrochloride
03/26/2014CN103664967A Method for synthesizing [2H3]-morphine
03/12/2014EP2705043A1 Processes and intermediates in the preparation of morphine analogs via n-demethylation of n-oxides using cyclodehydration reagents
03/12/2014EP2705040A1 Process for the preparation of morphine analogs via metal catalyzed n-demethylation/functionalization and intramolecular group transfer
03/12/2014CN103626782A Preparation method of methylnaltrexone bromide
03/06/2014WO2014033530A1 1,3-dioxanomorphides and 1,3-dioxanocodides
03/05/2014EP2703404A1 Buprenorphine analogs
03/05/2014CN103619847A Process for the preparation of morphine analogs via metal catalyzed N-demethylation/functionalization and intramolecular group transfer
02/2014
02/27/2014US20140057931 Buprenorphine analogs
02/20/2014US20140051861 Process for preparing oxymorphone, naltrexone, and buprenorphine
02/19/2014CN103596962A Processes and intermediates in the preparation of morphine analogs via N-demethylation of N-oxides using cyclodehydration reagents
02/18/2014US8653271 Enhancing transdermal delivery of opioid antagonists and agonists using codrugs linked to bupropion or hydroxybupropion
02/18/2014US8653065 Abuse deterrent and anti-dose dumping pharmaceutical salts useful for the treatment of attention deficit/hyperactivity disorder
02/13/2014US20140045876 Process
02/11/2014US8647667 Controlled release hydrocodone formulations
02/11/2014CA2628971C Therapeutic or prophylactic agent for functional bowel disorder
02/06/2014WO2014022733A1 A method for preparing oxycodone
02/04/2014US8642615 Methods of using 8-carboxamido-2,6-methano-3-benzazocines
01/2014
01/30/2014US20140031550 Process for the preparation of morphinane analogues
01/30/2014US20140031543 (+)-6-Hydroxy-Morphinan or (+)-6-Amino-Morphinan Derivatives
01/28/2014US8637539 Remedies for neuropathic pain and model animals of neuropathic pain
01/23/2014WO2014013313A1 Process for improved opioid synthesis
01/23/2014WO2014013311A1 Process for improved opioid synthesis
01/09/2014US20140013465 Papaver bracteatum with modified alkaloid content
01/08/2014CN101959892B Preparation and use of (R),(R)-2,2'-bis-methylnaltrexone
01/07/2014US8624031 Production of alkaloids without the isolation of intermediates
01/07/2014US8624030 N-demethylation of 6-keto morphinans
01/07/2014US8623888 3-oxy-hydromorphone derivatives
01/02/2014US20140005215 Selective Opioid Compounds
01/02/2014US20140004188 Crystal forms of (r)-n-methylnaltrexone bromide and uses thereof
12/2013
12/26/2013US20130345251 Large substituent, non-phenolic opioids and methods of use thereof
12/24/2013US8614224 Sinomenine derivatives and processes for their synthesis
12/19/2013WO2013188418A1 Improved method of preparing oxymorphone
12/19/2013US20130338365 Nalmefene hydrochloride dihydrate
12/18/2013CN103450206A Buprenorphine analogs
12/17/2013US8609682 Analgesic agents
12/12/2013WO2013184902A1 Chemical transformations of (-)-codeine to afford derivatives of codeine and morphine thereof
12/05/2013US20130323286 Synthesis of r-n-methylnaltrexone
12/03/2013US8598352 Preparation of nalmefene hydrochloride from naltrexone
11/2013
11/27/2013CN103408553A Refinement technique of hydromorphone acid salt
11/27/2013CN103405431A Opioid and opioid-like compounds and uses thereof
11/27/2013CN102127086B Method for preparing oxycodone hydrochloride having less than 25 ppm 14- hydroxycodeinone
11/20/2013EP2398808B1 Process for the reductive alkylation of normorphinans
11/20/2013EP2125824B1 Improved preparation of oxymorphone from oripavine
11/14/2013WO2013168011A1 Compositions and methods for the treatment of chronic pain
11/14/2013US20130302418 Controlled release hydrocodone formulations
11/13/2013CN103387579A Synthesis of 4-benzyloxy-17-benzenesulfonylmorphinan-6-one
11/13/2013CN103387578A Synthesis of 4-fluorobenzyloxy-6-hydroxy morphinan alkyl
11/13/2013CN102351869B Preparation method of high-purity methylnaltrexone bromide
11/12/2013US8580963 Method for the manufacturing of naltrexone
11/12/2013CA2610859C A synthetic route to 14-hydroxyl opiates through 1-halo-thebaine or analogs
11/07/2013WO2013166271A1 Heterocycle-fused morphinans, use thereof and preparation thereof
11/07/2013WO2013164383A1 Method for the manufacturing of naltrexone
11/07/2013WO2013163668A1 Papaver bracteatum with modified alkaloid content
11/07/2013WO2013050748A3 Process for preparing buprenorphine
11/07/2013US20130296570 Preparation and use of (r),(r)-2,2'-bis-methylnaltrexone
11/07/2013US20130295177 Controlled release hydrocodone
11/06/2013CN101801978B Methods for one-pot N-demethylation/N-acylation of morphine and tropane alkaloids
10/2013
10/31/2013US20130289060 6-AMIDO DERIVATIVES OF 4, 5-a EPOXYMORPHINANS FOR THE TREATMENT OF PAIN
10/29/2013US8569228 Compositions comprising enzyme-cleavable oxycodone prodrug
10/24/2013US20130281698 Novel 6-Amino-Morphinan Derivatives, Method of Manufacturing Them and Their Application as Analgesics
10/22/2013US8563726 Stereoselective reduction of a morphinone
10/22/2013US8563725 Preparation of saturated ketone morphinan compounds having low metal content
10/22/2013US8563724 (+)-6-hydroxy-morphinan or (+)-6-amino-morphinan derivatives
10/22/2013US8563721 Morphinan derivatives and preparation methods thereof
10/22/2013US8563571 Crystalline forms of oxymorphone hydrochloride
10/22/2013CA2538146C Pyridomorphinans, pyridazinomorphinans and use thereof
10/16/2013CN101208345B (S)-N-methylnaltrexone, processes for its synthesis and its pharmaceutical use
10/08/2013US8551520 Controlled release hydrocodone
10/01/2013US8546572 Process for the preparation of morphinane analogues
10/01/2013US8546418 Peripheral opioid receptor antagonists and uses thereof
10/01/2013CA2557845C Process for preparing, and composition and pharmaceutical dosage forms containing, an oxycodone salt having less than 25 ppm 14-hydroxycodeinone
09/2013
09/26/2013US20130253199 Polymorphic Forms of Naltrexone
09/26/2013US20130252994 Benzoic Acid, Benzoic Acid Derivatives and Heteroaryl Carboxylic Acid Conjugates of Hydrocodone, Prodrugs, Methods of Making and Use Thereof
09/18/2013EP2639234A1 Crystalline 6,7-unsaturated-7-carbamoyl morphinane derivative, and method for producing same
09/18/2013CN103304570A Naloxone hydrochloride compound as well as preparation method and pharmaceutical composition of naloxone hydrochloride compound
09/17/2013US8536192 6,7-unsaturated-7-carbamoyl substituted morphinan derivative
09/17/2013US8536191 Crystalline and amorphous forms of nalbuphine hydrochloride
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