Patents
Patents for C07H 21 - Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids (89,892)
09/1999
09/22/1999EP0943158A2 Affinity based self-assembly systems and devices for photonic and electronic applications
09/22/1999EP0620741B1 Cytotoxic drug therapy
09/21/1999US5955601 Useful in nucleic acid hybridization assays and for generating labelled probes; unusually high efficiency of rare earth element capture correlated with emission of a high level of signal in time-resolved fluorescence spectroscopy
09/21/1999US5955600 Method for the synthesis of nucleotide or oligonucleotide phosphoramidites
09/21/1999US5955599 Condensing in presence of 1h-tetrazole, a methoxy-3'-o (phosphoramidite) 5'-o-(4,4'-dimethoxytriphenyl) methyl nucleoside with another nucleoside; removing protective group without demethylating linkages
09/21/1999US5955597 Chirally enriched synthetic phosphate oligomers
09/21/1999US5955592 Nucleotide and amino acid sequences; for diagnosis of susceptiblity to cancer or diabetes
09/21/1999US5955591 Phosphotriester oligonucleotides, amidites and method of preparation
09/21/1999US5955590 Conjugates of minor groove DNA binders with antisense oligonucleotides
09/21/1999US5955589 Gapped 2' modified oligonucleotides
09/21/1999US5955583 Antibodies which bind to cyclic guanosine 3', 5' monophosphate enzyme involved in signal transduction
09/21/1999US5955446 Viricides for herpes infections
09/21/1999US5955366 Polynucleotides encoding cytokine suppressive anti-inflammatory drug binding proteins
09/21/1999US5955351 Self-contained device integrating nucleic acid extraction amplification and detection
09/21/1999US5955337 Lyase enzyme which can be used to screen fungicidal compounds
09/21/1999US5955307 Plasmid vector and use thereof for the production of interferon
09/21/1999US5955271 Reverse transcription and amplification in same heat stable reaction vessel; vessel has interior coated with chemical which binds label on hybridization partner
09/21/1999US5955260 Antibodies that bind viral proteins that share homogeneity; for diagnostic immunoassay of virus in sample
09/21/1999US5955258 Using homologous and heterologous proteolytic enzymes from gram positive lactobacillus to disrupt bacterial cell in culture; bactericides; to prevent food spoilage and improving self life;food processing of cheese
09/21/1999US5955090 Immunogenic hybrid protein OprF-OprI derived from Pseudomonas aeruginosa membrane proteins
09/21/1999US5955059 Treating psoriasis, other skin disorders
09/16/1999WO1999046408A1 Detection of neoplasia by analysis of saliva
09/16/1999WO1999046400A1 Compositions and methods for enhanced synthesis of nucleic acid molecules
09/16/1999WO1999046274A1 Modified factor viii
09/16/1999WO1999045935A1 Novel nucleoside analogs and uses in treating disease
09/16/1999WO1999024452A3 Pyrimidine derivatives for labeled binding partners
09/16/1999WO1999021873A3 Synthesis of polynucleotides having random sequences
09/16/1999WO1999020640A3 High surface density covalent immobilization of oligonucleotide monolayers
09/16/1999WO1998041531A3 Solvent for biopolymer synthesis, solvent microdroplets and methods of use
09/16/1999CA2421272A1 Novel polypeptides and nucleic acids encoding the same
09/16/1999CA2323060A1 Detection of neoplasia by analysis of saliva
09/16/1999CA2322620A1 Compositions and methods for enhanced synthesis of nucleic acid molecules
09/16/1999CA2322508A1 Modified factor viii
09/16/1999CA2322494A1 Novel nucleoside analogs and uses in treating disease
09/16/1999CA2321677A1 Novel polypeptides and nucleic acids encoding the same which are useful for treating inner ear diseases
09/15/1999EP0942000A2 2'Modified oligonucleotides
09/15/1999EP0941370A2 Stabilized aqueous nucleoside triphosphate solution
09/15/1999EP0941360A1 Compositions and methods for rapid isolation of plasmid dna
09/15/1999EP0941314A1 Target nucleic acid sequence amplification method
09/15/1999EP0941124A1 Antisense oligonucleotide compositions for selectively killing cancer cells
09/15/1999EP0748383B1 Targeted cleavage of rna using ribonuclease p targeting and cleavage sequences
09/15/1999EP0596918B1 Amplification of target nucleic acids using gap filling ligase chain reaction
09/14/1999US5952490 Oligonucleotides having a conserved G4 core sequence
09/14/1999US5952488 A nucleic acid molecule containing an androgen response element linked to a reporter gene; diagnosis and therapy for prostatic diseases and cancer
09/14/1999US5952481 DNA encoding ubiquitin conjugating enzymes
09/14/1999US5952478 Nucleotides and analogs in which both the 3' oxy linkage and the 5' oxy linkage are replaced by carbon linkages; for antisense agents; viricides against influenza, herpes and human immune deficiency virus; anticarcinogenic agents
09/14/1999US5952472 Anti-fibroblast growth factor-8 monoclonal antibody
09/14/1999US5952463 Amino acid sequence of a protein which inhibits enzymes from kex2 family; development of new medicines and pesticides
09/14/1999US5952311 Photosensitizing chemical means for killing tumor cells, wherein tumoricidal activity is activated by absorbing light or energy within a specific wavelength range, and energy donating chemical means for activating photosensitizer
09/14/1999US5952225 A packaging cell containing a polynucleotide which codes a portion of a selected retrovirus having at least the envelope protein; for producing vectors resistant to complement inactivation by serum; gene therapy
09/14/1999US5952211 Method for producing active human alanine aminotransferase
09/14/1999US5952202 Using internal control polynucleotide and primers, target polynucleotides and primers, non-extendable oligonucleotide complementary to the internal control primers, polymerase with exonuclease activity, self-quenching fluorescent probes
09/14/1999US5952172 Alternating current input signal to a hybridization complex with single stranded nucleic acid containing a covalently attached electron transfer moiety and electrode, detecting target sequence via output signal
09/14/1999CA2170869C Amine-derivatized nucleosides and oligonucleosides
09/14/1999CA2071446C Synthetic catalytic oligonucleotide structures
09/14/1999CA1340748C Synthetic hiv protease gene and method for its expression
09/14/1999CA1340736C Method for genetically modifying a plant cell for plant gene expression
09/14/1999CA1340733C Regulatory region for heterologous gene expression in yeast
09/10/1999WO1999045017A1 Methyl red energy transfer reagent for dna analysis
09/10/1999WO1999044741A1 Reaction block docking station
09/10/1999WO1999044620A1 Asthma associated factors as targets for treating atopic allergies including asthma and related disorders
09/10/1999WO1999032616A3 Method for isolating short and long-chain nucleic acids
09/10/1999WO1999027081A9 Alpha/beta hydrolase-fold enzymes
09/10/1999CA2291767A1 Reaction block docking station
09/08/1999EP0940450A1 Energy transfer dyes with enhanced fluorescence
09/08/1999EP0939820A1 Nucleic acid sequences that encode a cell growth regulatory protein and uses thereof
09/08/1999EP0939762A2 Electrodes linked via conductive oligomers to nucleic acids
09/08/1999EP0832298A4 Detecting genetic predisposition for osteoporosis
09/08/1999EP0510085B1 Dna-dependent rna polymerase transcripts as reporter molecules for signal amplification in nucleic acid hybridization assays
09/08/1999CN1227845A Process for extracting ribonucleic acid (RNA) from beer waste liquid
09/07/1999US5948901 Antisense oligonucleotides for aromatase inhibition
09/07/1999US5948898 Methoxyethoxy oligonucleotides for modulation of protein kinase C expression
09/07/1999US5948678 This invention also relates to the use of i-scei for mapping eukaryotic genomes and for in vivo site directed genetic recombination.
09/07/1999US5948675 Host-vector system which can be used in gene therapy
09/07/1999US5948659 Recombinant fructosyl amino acid oxidase
09/07/1999US5948656 Proteins which bind to cytolytic lymphocyte cytoplasmic granule associated rna binding proteins; anticarcinogenic agents; treatment of graft vs. host disease, allograft rejection, transplantation organ rejections
09/07/1999US5948648 Base portion, rigid linker, spacer, and linkage pair or label; for use as chain extenders or chain terminators in sanger sequencing reactions or polymerase chain reactions
09/07/1999US5948646 Making complementary dna from rna isolated from cancer or preneoplastic cells, ligating into constructs forming library, introducing library into host cells, culturing causing gene expression, recovering immunogenic complexes
09/07/1999US5948640 Mammalian additional sex combs (mammalian Asx) acts as a tumor suppressor
09/07/1999US5948635 Totally Synthetic Affinity Reagents
09/07/1999US5948624 Methods for the detection and isolation of biomolecules
09/07/1999US5948617 Using glycerol-based, formamide-free solution for both denaturation of nucleic acids and hybridization of labeled (e.g. fluorescence) synthetic oligonucleotide probes; washing and hybridization at same temperature; archival storage
09/07/1999US5948614 Free of exonuclease activity and non-discriminating against dideoxynucleotides; more heat resistant than thermus polymerase; for sequence determination, amplification, and complementary dna synthesis
09/07/1999CA2138765C Recombinant haemophilus influenzae protein and nucleotide sequence encoding same
09/02/1999WO1999043697A1 Manganese superoxide dismutase exon 3-deleted isoforms and nucleic acid molecules encoding the isoforms
09/02/1999WO1999043694A1 Improved methods for synthesis of oligonucleotides
09/02/1999WO1999043693A1 36 human secreted proteins
09/02/1999WO1999043688A1 Photoactivatable nucleic acid derivatives
09/02/1999WO1999043287A2 Phosphate-based dendrimers for bioassays
09/02/1999WO1999033867A3 Modified nucleic acid analogues
09/02/1999WO1999028485A3 Ribozymes capable of conferring resistance to potyvirus infection, and plants expressing said ribozymes
09/02/1999WO1999022772A9 LIPOSOMAL OLIGONUCLEOTIDE COMPOSITIONS FOR MODULATING ras GENE EXPRESSION
09/02/1999WO1999020766A3 NOVEL MODIFIED NUCLEIC ACID SEQUENCES AND METHODS FOR INCREASING mRNA LEVELS AND PROTEIN EXPRESSION IN CELL SYSTEMS
09/02/1999CA2321970A1 36 human secreted proteins
09/02/1999CA2321098A1 Photoactivatable nucleic acid derivatives
09/01/1999EP0765335B1 Universal process for isolating and purifying nucleic acids from extremely small amounts of highly contaminated various starting materials
09/01/1999EP0752882A4 Treatment for juvenile diabetes
09/01/1999CN1227608A Transcriptional silencing elements and their binding factors
09/01/1999CN1227604A Multivarient IL-3 hematopoiesis fusion protein
09/01/1999CN1227496A Screening method for compounds useful in the regulation of body weight