Patents for C07H 21 - Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids (89,892) |
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09/22/1999 | EP0943158A2 Affinity based self-assembly systems and devices for photonic and electronic applications |
09/22/1999 | EP0620741B1 Cytotoxic drug therapy |
09/21/1999 | US5955601 Useful in nucleic acid hybridization assays and for generating labelled probes; unusually high efficiency of rare earth element capture correlated with emission of a high level of signal in time-resolved fluorescence spectroscopy |
09/21/1999 | US5955600 Method for the synthesis of nucleotide or oligonucleotide phosphoramidites |
09/21/1999 | US5955599 Condensing in presence of 1h-tetrazole, a methoxy-3'-o (phosphoramidite) 5'-o-(4,4'-dimethoxytriphenyl) methyl nucleoside with another nucleoside; removing protective group without demethylating linkages |
09/21/1999 | US5955597 Chirally enriched synthetic phosphate oligomers |
09/21/1999 | US5955592 Nucleotide and amino acid sequences; for diagnosis of susceptiblity to cancer or diabetes |
09/21/1999 | US5955591 Phosphotriester oligonucleotides, amidites and method of preparation |
09/21/1999 | US5955590 Conjugates of minor groove DNA binders with antisense oligonucleotides |
09/21/1999 | US5955589 Gapped 2' modified oligonucleotides |
09/21/1999 | US5955583 Antibodies which bind to cyclic guanosine 3', 5' monophosphate enzyme involved in signal transduction |
09/21/1999 | US5955446 Viricides for herpes infections |
09/21/1999 | US5955366 Polynucleotides encoding cytokine suppressive anti-inflammatory drug binding proteins |
09/21/1999 | US5955351 Self-contained device integrating nucleic acid extraction amplification and detection |
09/21/1999 | US5955337 Lyase enzyme which can be used to screen fungicidal compounds |
09/21/1999 | US5955307 Plasmid vector and use thereof for the production of interferon |
09/21/1999 | US5955271 Reverse transcription and amplification in same heat stable reaction vessel; vessel has interior coated with chemical which binds label on hybridization partner |
09/21/1999 | US5955260 Antibodies that bind viral proteins that share homogeneity; for diagnostic immunoassay of virus in sample |
09/21/1999 | US5955258 Using homologous and heterologous proteolytic enzymes from gram positive lactobacillus to disrupt bacterial cell in culture; bactericides; to prevent food spoilage and improving self life;food processing of cheese |
09/21/1999 | US5955090 Immunogenic hybrid protein OprF-OprI derived from Pseudomonas aeruginosa membrane proteins |
09/21/1999 | US5955059 Treating psoriasis, other skin disorders |
09/16/1999 | WO1999046408A1 Detection of neoplasia by analysis of saliva |
09/16/1999 | WO1999046400A1 Compositions and methods for enhanced synthesis of nucleic acid molecules |
09/16/1999 | WO1999046274A1 Modified factor viii |
09/16/1999 | WO1999045935A1 Novel nucleoside analogs and uses in treating disease |
09/16/1999 | WO1999024452A3 Pyrimidine derivatives for labeled binding partners |
09/16/1999 | WO1999021873A3 Synthesis of polynucleotides having random sequences |
09/16/1999 | WO1999020640A3 High surface density covalent immobilization of oligonucleotide monolayers |
09/16/1999 | WO1998041531A3 Solvent for biopolymer synthesis, solvent microdroplets and methods of use |
09/16/1999 | CA2421272A1 Novel polypeptides and nucleic acids encoding the same |
09/16/1999 | CA2323060A1 Detection of neoplasia by analysis of saliva |
09/16/1999 | CA2322620A1 Compositions and methods for enhanced synthesis of nucleic acid molecules |
09/16/1999 | CA2322508A1 Modified factor viii |
09/16/1999 | CA2322494A1 Novel nucleoside analogs and uses in treating disease |
09/16/1999 | CA2321677A1 Novel polypeptides and nucleic acids encoding the same which are useful for treating inner ear diseases |
09/15/1999 | EP0942000A2 2'Modified oligonucleotides |
09/15/1999 | EP0941370A2 Stabilized aqueous nucleoside triphosphate solution |
09/15/1999 | EP0941360A1 Compositions and methods for rapid isolation of plasmid dna |
09/15/1999 | EP0941314A1 Target nucleic acid sequence amplification method |
09/15/1999 | EP0941124A1 Antisense oligonucleotide compositions for selectively killing cancer cells |
09/15/1999 | EP0748383B1 Targeted cleavage of rna using ribonuclease p targeting and cleavage sequences |
09/15/1999 | EP0596918B1 Amplification of target nucleic acids using gap filling ligase chain reaction |
09/14/1999 | US5952490 Oligonucleotides having a conserved G4 core sequence |
09/14/1999 | US5952488 A nucleic acid molecule containing an androgen response element linked to a reporter gene; diagnosis and therapy for prostatic diseases and cancer |
09/14/1999 | US5952481 DNA encoding ubiquitin conjugating enzymes |
09/14/1999 | US5952478 Nucleotides and analogs in which both the 3' oxy linkage and the 5' oxy linkage are replaced by carbon linkages; for antisense agents; viricides against influenza, herpes and human immune deficiency virus; anticarcinogenic agents |
09/14/1999 | US5952472 Anti-fibroblast growth factor-8 monoclonal antibody |
09/14/1999 | US5952463 Amino acid sequence of a protein which inhibits enzymes from kex2 family; development of new medicines and pesticides |
09/14/1999 | US5952311 Photosensitizing chemical means for killing tumor cells, wherein tumoricidal activity is activated by absorbing light or energy within a specific wavelength range, and energy donating chemical means for activating photosensitizer |
09/14/1999 | US5952225 A packaging cell containing a polynucleotide which codes a portion of a selected retrovirus having at least the envelope protein; for producing vectors resistant to complement inactivation by serum; gene therapy |
09/14/1999 | US5952211 Method for producing active human alanine aminotransferase |
09/14/1999 | US5952202 Using internal control polynucleotide and primers, target polynucleotides and primers, non-extendable oligonucleotide complementary to the internal control primers, polymerase with exonuclease activity, self-quenching fluorescent probes |
09/14/1999 | US5952172 Alternating current input signal to a hybridization complex with single stranded nucleic acid containing a covalently attached electron transfer moiety and electrode, detecting target sequence via output signal |
09/14/1999 | CA2170869C Amine-derivatized nucleosides and oligonucleosides |
09/14/1999 | CA2071446C Synthetic catalytic oligonucleotide structures |
09/14/1999 | CA1340748C Synthetic hiv protease gene and method for its expression |
09/14/1999 | CA1340736C Method for genetically modifying a plant cell for plant gene expression |
09/14/1999 | CA1340733C Regulatory region for heterologous gene expression in yeast |
09/10/1999 | WO1999045017A1 Methyl red energy transfer reagent for dna analysis |
09/10/1999 | WO1999044741A1 Reaction block docking station |
09/10/1999 | WO1999044620A1 Asthma associated factors as targets for treating atopic allergies including asthma and related disorders |
09/10/1999 | WO1999032616A3 Method for isolating short and long-chain nucleic acids |
09/10/1999 | WO1999027081A9 Alpha/beta hydrolase-fold enzymes |
09/10/1999 | CA2291767A1 Reaction block docking station |
09/08/1999 | EP0940450A1 Energy transfer dyes with enhanced fluorescence |
09/08/1999 | EP0939820A1 Nucleic acid sequences that encode a cell growth regulatory protein and uses thereof |
09/08/1999 | EP0939762A2 Electrodes linked via conductive oligomers to nucleic acids |
09/08/1999 | EP0832298A4 Detecting genetic predisposition for osteoporosis |
09/08/1999 | EP0510085B1 Dna-dependent rna polymerase transcripts as reporter molecules for signal amplification in nucleic acid hybridization assays |
09/08/1999 | CN1227845A Process for extracting ribonucleic acid (RNA) from beer waste liquid |
09/07/1999 | US5948901 Antisense oligonucleotides for aromatase inhibition |
09/07/1999 | US5948898 Methoxyethoxy oligonucleotides for modulation of protein kinase C expression |
09/07/1999 | US5948678 This invention also relates to the use of i-scei for mapping eukaryotic genomes and for in vivo site directed genetic recombination. |
09/07/1999 | US5948675 Host-vector system which can be used in gene therapy |
09/07/1999 | US5948659 Recombinant fructosyl amino acid oxidase |
09/07/1999 | US5948656 Proteins which bind to cytolytic lymphocyte cytoplasmic granule associated rna binding proteins; anticarcinogenic agents; treatment of graft vs. host disease, allograft rejection, transplantation organ rejections |
09/07/1999 | US5948648 Base portion, rigid linker, spacer, and linkage pair or label; for use as chain extenders or chain terminators in sanger sequencing reactions or polymerase chain reactions |
09/07/1999 | US5948646 Making complementary dna from rna isolated from cancer or preneoplastic cells, ligating into constructs forming library, introducing library into host cells, culturing causing gene expression, recovering immunogenic complexes |
09/07/1999 | US5948640 Mammalian additional sex combs (mammalian Asx) acts as a tumor suppressor |
09/07/1999 | US5948635 Totally Synthetic Affinity Reagents |
09/07/1999 | US5948624 Methods for the detection and isolation of biomolecules |
09/07/1999 | US5948617 Using glycerol-based, formamide-free solution for both denaturation of nucleic acids and hybridization of labeled (e.g. fluorescence) synthetic oligonucleotide probes; washing and hybridization at same temperature; archival storage |
09/07/1999 | US5948614 Free of exonuclease activity and non-discriminating against dideoxynucleotides; more heat resistant than thermus polymerase; for sequence determination, amplification, and complementary dna synthesis |
09/07/1999 | CA2138765C Recombinant haemophilus influenzae protein and nucleotide sequence encoding same |
09/02/1999 | WO1999043697A1 Manganese superoxide dismutase exon 3-deleted isoforms and nucleic acid molecules encoding the isoforms |
09/02/1999 | WO1999043694A1 Improved methods for synthesis of oligonucleotides |
09/02/1999 | WO1999043693A1 36 human secreted proteins |
09/02/1999 | WO1999043688A1 Photoactivatable nucleic acid derivatives |
09/02/1999 | WO1999043287A2 Phosphate-based dendrimers for bioassays |
09/02/1999 | WO1999033867A3 Modified nucleic acid analogues |
09/02/1999 | WO1999028485A3 Ribozymes capable of conferring resistance to potyvirus infection, and plants expressing said ribozymes |
09/02/1999 | WO1999022772A9 LIPOSOMAL OLIGONUCLEOTIDE COMPOSITIONS FOR MODULATING ras GENE EXPRESSION |
09/02/1999 | WO1999020766A3 NOVEL MODIFIED NUCLEIC ACID SEQUENCES AND METHODS FOR INCREASING mRNA LEVELS AND PROTEIN EXPRESSION IN CELL SYSTEMS |
09/02/1999 | CA2321970A1 36 human secreted proteins |
09/02/1999 | CA2321098A1 Photoactivatable nucleic acid derivatives |
09/01/1999 | EP0765335B1 Universal process for isolating and purifying nucleic acids from extremely small amounts of highly contaminated various starting materials |
09/01/1999 | EP0752882A4 Treatment for juvenile diabetes |
09/01/1999 | CN1227608A Transcriptional silencing elements and their binding factors |
09/01/1999 | CN1227604A Multivarient IL-3 hematopoiesis fusion protein |
09/01/1999 | CN1227496A Screening method for compounds useful in the regulation of body weight |