Patents
Patents for C07H 21 - Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids (89,892)
04/1999
04/21/1999EP0909815A2 Dna sequence conferring cytoplasmic male sterility, mitochondrial genome, nuclear genome, mitochondria and plant containing said sequence and process for the preparation of hybrids
04/21/1999EP0688366A4 Sensitive nucleic acid sandwich hybridization assays and kits
04/21/1999EP0674660B1 Multifunctional neurotrophic factors
04/21/1999EP0543889B1 Incorporation of selectably clevable sites into oligonucleotide chains and reagents therefor
04/21/1999EP0500779B1 4,7-dichlorofluorescein dyes as molecular probes
04/21/1999CN1214688A Sugar-modified gapped oligonucleotides
04/21/1999CN1043045C Oligonucleotide capable of inhibiting endothelin generation
04/20/1999US5895833 Gene expression compatible with mammary glands
04/15/1999WO1999018238A1 Combinatorial antisense library
04/15/1999WO1999018114A1 Novel nucleoside or nucleotide fluorescent conjugates, preparation method and uses
04/15/1999WO1999017797A1 Use of growth differenciation factor-9 (gdf-9) as a contraceptive
04/15/1999WO1999004041A9 Methods and compositions for modulating melting temperatures of nucleic acids
04/15/1999WO1998059058A3 Polynucleotides and their use for detecting resistance to streptogramin a or to streptogramin b and related compounds
04/15/1999WO1998056943A9 Covalent joining of dna strands to rna strands catalyzed by vaccinia topoisomerase
04/15/1999WO1998043993A3 Nucleic acid catalysts
04/15/1999CA2306452A1 Use of growth differentiation factor-9 (gdf-9) as a contraceptive
04/15/1999CA2305811A1 Novel nucleoside or nucleotide fluorescent conjugates, preparation method and uses
04/15/1999CA2304798A1 Combinatorial antisense library
04/14/1999EP0794782A4 Cobalt schiff base compounds
04/14/1999EP0734436B1 Inhibition of dna methyltransferase
04/14/1999EP0682715A4 Diagnostic assays and kits for rna using rna binary probes and an rna-directed rna ligase.
04/14/1999EP0658167B1 4,7-dichlorofluorescein dyes as molecular probes
04/14/1999EP0643559B1 Diphtheria toxin receptor-binding region
04/14/1999EP0548200B1 Cloning and sequencing of allergens of dermatophagoides (house dust mite)
04/14/1999CN1214050A Human tumor necrosis factor delta and epsilon
04/14/1999CN1213962A Method for solubilising hydrophylic materials (E. G. proteins) in hydrophobic solvent
04/08/1999WO1999016832A1 Aromatic-substituted xanthene dyes
04/08/1999WO1999016409A2 Gene therapy approaches to supply apolipoprotein a-i agonists and their use to treat dyslipidemic disorders
04/08/1999WO1999005160A3 Oligonuclotides having 3' terminal stereospecific phosphorothioates
04/08/1999WO1999003873A3 Novel sulfurizing reagent 3-phenyl-1,2,4-dithiazoline-5-one
04/08/1999WO1998056955A9 Method of in situ hybridization
04/08/1999CA2304814A1 Gene therapy approaches to supply apolipoprotein a-i agonists and their use to treat dyslipidemic disorders
04/07/1999EP0906917A2 Method for chemical synthesis of oligonucleotides
04/07/1999EP0906448A1 Methods for the diagnosis and prognosis of cancer
04/07/1999EP0906420A1 Programmed sequential mutagenesis
04/07/1999EP0906329A2 2'-substituted nucleosides and oligonucleotide derivatives
04/07/1999EP0906328A1 Methods and compounds for curing diseases caused by mutations
04/07/1999EP0906327A2 Intermediates for oligonucleotide synthesis
04/07/1999EP0906123A1 OLIGONUCLEOTIDES TARGETED TO ANGIOTENSINOGEN mRNA
04/07/1999EP0906110A1 Dna vaccine formulations
04/07/1999EP0754227A4 Chimeric complement inhibitor proteins
04/07/1999CN1213406A Method for inhibiting adenylosuccinate synthetase activity methylthioadenosine phosphorylasse deficient cells
04/07/1999CN1213312A Anticogulant agent useful in treatment of thrombosis
04/06/1999US5892024 Bifunctional nucleosides, oligomers thereof, and methods of making and using the same
04/06/1999US5892007 Protecting at least one group in at least one compound in a mixture of compounds to be separated with a multiple fused ring protecting group, passing the mixture through a chamber filled with a reverse phase silica gel or polystyrene material
04/06/1999US5891997 Receptor for oncostatin M
04/06/1999US5891996 Humanized and chimeric monoclonal antibodies that recognize epidermal growth factor receptor (EGF-R); diagnostic and therapeutic use
04/06/1999US5891725 Synthetic antisense oligodeoxynucleotides and pharmaceutical compositions containing them
04/06/1999US5891700 Receptor-type phosphotyrosine phosphatase-γ
04/06/1999US5891694 Method for recovering nucleic acid and device for the same purpose
04/06/1999US5891687 Positive selection vector based on the caps gene, pCAPs vector and its use
04/06/1999US5891684 Base-modified enzymatic nucleic acid
04/06/1999US5891683 Having enzymatic activity to cleave a target rna molecule, wherein said enzymatic nucleic acid molecule comprises an abasic moiety in a single-stranded region of said enzymatic nucleic acid molecule.
04/06/1999US5891672 Polynucleotides encoding GTP cyclohydrolase II (ribA)
04/06/1999US5891671 Method for cleaving chimeric protein using processing enzyme
04/06/1999US5891665 Rna subsequence comprising a 5' signal sequence of a non-structural gene linked to a second heterologous sequence downstream; enhanced for increased protein production
04/06/1999US5891627 This invention generally relates to the detection of a polymorphic locus nucleotide sequence which can be used to identify an individual of a species.
04/06/1999US5891625 Use of nucleic acid analogues in the inhibition of nucleic acid amplification
04/06/1999US5891437 Antigen associated with type I diabetes mellitus
04/06/1999US5891436 The present invention thus provides the basis of an extremely sensitive and specific diagnostic elisa for anti-70 kd antibodies found in pbc.
04/06/1999US5891430 Diabetogene rad: a type II diabetes specific gene
04/01/1999WO1999015703A1 Inhibition of an fgf-binding protein using ribozymes
04/01/1999WO1999015702A1 Normalized nucleic acid libraries and methods of production thereof
04/01/1999WO1999015645A1 Method for isolating dna
04/01/1999WO1999015542A2 Linker nucleoside, and production and use of the same
04/01/1999WO1999015541A2 Use of a pentopyranosyl nucleoside for producing an electronic component, and conjugates of said pentopyranosyl nucleoside
04/01/1999WO1999015540A2 Method for producing a pentopyranosyl nucleoside
04/01/1999WO1999015539A2 Pentopyranosyl nucleoside, and production and use of the same
04/01/1999WO1999015517A1 Sulfonated xanthene derivatives
04/01/1999WO1998054198A9 Novel sulfur transfer reagents for oligonucleotide synthesis
04/01/1999CA2304895A1 Normalized nucleic acid libraries and methods of production thereof
04/01/1999CA2303784A1 Use of a pentopyranosylnucleoside for the production of an electronic component, and conjugates thereof
04/01/1999CA2303527A1 Linker nucleoside, its preparation and use
04/01/1999CA2302414A1 Process for the preparation of a pentopyranosylnucleoside
04/01/1999CA2272403A1 Sulfonated xanthene derivatives
03/1999
03/31/1999EP0905258A2 Method for detecting nucleic acid sequences based on the use of solid phase immobilised nucleotide probes (line probe assay)
03/31/1999EP0905254A2 DNA vector associated with biocompatible low molecular weight polyethyleneimines
03/31/1999EP0905253A2 Adenoviral vector deleted of all E4-ORF except ORF6
03/31/1999EP0905246A1 Cloning of chicken anaemia DNA
03/31/1999EP0905236A1 Transcription factor DP-1
03/31/1999EP0904399A1 $g(a)2 SUBUNIT OF PROLYL-4-HYDROXYLASE NUCLEIC ACID SEQUENCES ENCODING SUCH SUBUNIT AND METHODS FOR PRODUCING THE SAME
03/31/1999EP0904275A1 Preparation of phosphorothioate oligomers
03/31/1999EP0904103A1 POLYNUCLEOTIDES AND POLYPEPTIDES OF THE GLUTAMYL tRNA SYNTHETASE FAMILY
03/31/1999EP0904095A1 Chimeric isoprenoid synthases and uses thereof
03/31/1999EP0690929A4 NUCLEIC ACID PROBES FOR THE DETECTION OF -i(HAEMOPHILUS INFLUENZAE)
03/31/1999CN1212701A Oligonucleotide analogues
03/30/1999US5889173 DNA encoding multifunctional neurothrophic factors
03/30/1999US5889168 Fusion glycoprotein from HCMV and HSV
03/30/1999US5889165 Photolabile nucleoside protecting groups
03/30/1999US5889143 Evaluation and treatment of patients with progressive immunosuppression
03/30/1999US5889136 Phosphoramidite oligonucleotide biosynthesis
03/30/1999US5888997 Radiation sensitization using texaphyrins
03/30/1999US5888983 Inserting dna, rna into cells to repair genetic disorders
03/30/1999US5888820 Retroviral vector capable of transducing the aldehyde dehydrogenase-1 gene and uses of said vector
03/30/1999US5888812 Myeloid cell leukemia associated gene MCL-1
03/30/1999US5888808 Bacterial polypeptide expression employing tryptophan promoter-operator
03/30/1999US5888802 Thermostable xylanase
03/30/1999US5888780 Using enzymes
03/30/1999US5888772 Amino acid sequences of mutants with higher biological activity; for treatment of anemia and induction of erythropoiesis
03/30/1999US5888766 Method for producing recombinant human myoglobin