Patents
Patents for C07H 21 - Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids (89,892)
02/2000
02/02/2000EP0975650A1 Oligomers which inhibit expression of collagen genes
02/02/2000EP0975649A1 Rnase l activators and antisense oligonucleotides effective to treat telomerase-expressing malignancies
02/02/2000EP0713532B1 Modified maxadilan protein, its preparation and use, and dna encoding the protein
02/02/2000EP0713529B1 Growth differentiation factor of the TGF-B family
02/01/2000US6020481 Fluorescent labeling reagents; dideoxy polynucleotide sequencing and fragment analysis methods.
02/01/2000US6020475 Process for the synthesis of oligomeric compounds
02/01/2000US6020466 Myeloid cell leukemia associated gene mcl-1
02/01/2000US6020464 Isolated Smad protein
02/01/2000US6020188 Polynucleotides encoding platelet endothelial cell adhesion molecule (PECAM-1) and fragments thereof
02/01/2000US6020176 Converting copalyl pyrophosphate to ent-kaurene and are useful for the regulation of plant growth.
02/01/2000US6020168 Porcine CNP gene and precursor protein
02/01/2000US6020126 Rapid genetic screening method
02/01/2000US6019978 Replication-defective adenovirus human type 5 recombinant as a vaccine carrier
02/01/2000CA2171982C Drug binding protein
01/2000
01/27/2000WO2000004189A1 Modified oligonucleotides
01/27/2000WO2000004183A1 Bone morphogenic protein
01/27/2000WO2000004177A1 Chromatin associated proteins
01/27/2000WO2000004140A1 71 human secreted proteins
01/27/2000WO2000004139A1 Micellar systems
01/27/2000WO2000004043A1 Protease susceptibility ii
01/27/2000WO2000004036A1 Photocleavable nucleoside base
01/27/2000WO2000004034A2 Oligonucleotides having site specific chiral phosphorothioate internucleoside linkages
01/27/2000WO2000004007A1 Fluorescent dibenzazole derivatives and methods related thereto
01/27/2000WO2000003720A1 Carbohydrate or 2'-modified oligonucleotides having alternating internucleoside linkages
01/27/2000WO1999052925A9 Programmed cell death and caspase-12
01/27/2000WO1999039735A9 Live vaccine for human immunodeficiency virus
01/27/2000CA2334075A1 Bone morphogenic protein
01/27/2000CA2333917A1 71 human secreted proteins
01/26/2000EP0974663A1 Lipoprotein associated phospholipase A2, inhibitors thereof and use of same in diagnosis and therapy
01/26/2000EP0974658A1 PROBES FOR THE DIAGNOSIS OF INFECTIONS CAUSED BY $i(STREPTOCOCCUS PYOGENES)
01/26/2000EP0973788A1 Tricyclic base analogues
01/26/2000EP0973785A1 Trans-platinum compound, and diagnostic kit
01/26/2000CN1242775A G-rich oligo aptamers and methods of modulating immune response
01/26/2000CN1048731C Polynucleotide of drug binding protein as coded CSAID
01/25/2000US6018104 Nucleic acid promoter fragment isolated from a plant tryptophan synthase alpha subunit (trpA) gene
01/25/2000US6018042 An oligonucleotide derivative capable of modulating the biosynthesis of human s-adenosylmethionine decarboxylase enzyme; antiproliferative/antitumor/antimetastasis agents
01/25/2000US6018019 Immunogenic synthetic peptides which are useful alone or in conjugates in vaccines against hemophilus influenza infection
01/25/2000US6017898 Inhibition of tumor growth by antisense oligonucleotides for IL-8 and IL-8 receptor
01/25/2000US6017895 Oligonucleotides possessing zwitterionic moieties
01/25/2000US6017759 Chimeric infectious bursal disease virus cDNA clones, expression products and vaccines based thereon
01/25/2000US6017743 Dna which codes for a glycosyltransferase which adds oligosialic acids to glycoproteins and glycolipids; for anticarcinogenic/antimetastasis/antiinflammatory agents; for maturation of sperm and reactivation of nervous tissues
01/25/2000US6017742 Immobilization of biologically active substances on a carrier containing a carbodiimide group-containing polymer
01/25/2000US6017712 Nucleotide labeled with xanthene dye having narrower emission spectrum and with absorption spectrum shifted to the red; for molecular probes and in nucleic acid sequencing
01/25/2000US6017700 Cationic oligonucleotides, and related methods of synthesis and use
01/25/2000US6017696 Controlling nucleic acid hybridization by connecting multiple electrical sources to several location where a plurality of nucleic acids with target nucleic acids are attached, apply a negative potential, removing non specific nucleic acid
01/25/2000US6017695 A polynucleotide sequence that encodes a human brain glycoprotein, contactin; to study signal transmissions, cell morphology, cell metabolism and cell adhesion
01/25/2000US6017542 Nucleotide and amino acid sequences of canine herpesvirus GD and uses therefor
01/25/2000US6017496 Matrices with memories and uses thereof
01/25/2000CA2184005C Novel phosphoramidate and phophorothioamidate oligomeric compounds
01/25/2000CA1340881C Nucleic acid probes for detecting human papillomavirus
01/20/2000WO2000003039A1 Methods for determining cross-hybridization
01/20/2000WO2000002896A1 Improved process for the synthesis of oligonucleotides and analogues thereof
01/20/2000WO2000002895A1 Arylsulfone linkers for mass spectrometric analysis
01/20/2000WO2000002894A1 Silicon-containing linkers for nucleic acid mass markers
01/20/2000WO2000002893A1 Metal ion-binding mass markers for nucleic acids
01/20/2000WO1999060007A3 Libraries of oligomers labelled with different tags
01/20/2000WO1999055913A3 Reduced complexity nucleic acid targets and methods of using same
01/20/2000CA2385987A1 Arylsulfone linkers for mass spectrometric analysis
01/20/2000CA2385970A1 Silicon-containing linkers for nucleic acid mass markers
01/20/2000CA2385962A1 Metal ion-binding mass markers for nucleic acids
01/19/2000EP0972848A2 Self-quenching fluorescence probe and method
01/19/2000EP0972833A1 PROBES FOR THE DIAGNOSIS OF INFECTIONS CAUSED BY $i(KLEBSIELLA PNEUMONIAE)
01/19/2000EP0972779A2 Oligonucleotide-polyamide conjugates
01/19/2000EP0972564A2 Combinatorial strategies for polymer synthesis
01/19/2000EP0972082A1 Closed-loop biochemical analyzers
01/19/2000EP0972025A1 I-flice, a novel inhibitor of tumor necrosis factor receptor-1 and cd-95 induced apoptosis
01/19/2000EP0972015A1 Enzyme having s-adenosyl-l-homocysteine hydrolase (ahcy) type activity
01/19/2000EP0971945A1 Uronium salt conjugate vaccines
01/19/2000EP0971944A1 Anti-viral guanosine-rich tetrad forming oligonucleotides
01/19/2000EP0971943A1 Nucleic acid-containing polymerizable complex
01/19/2000EP0830363A4 Chemical ligation of template-directed oligonucleotides
01/19/2000CN1241945A Isolated peptides which complex with HLA-Cw*16 molecules, and ues thereof
01/19/2000CN1241901A Coat protein mediated resistance in plants
01/18/2000US6015895 Linker arm for solid support oligonucleotide synthesis and process for production thereof
01/18/2000US6015894 Oligonucleotide modulation of cell adhesion
01/18/2000US6015893 Oligonucleoside compounds and methods for inhibiting tumor growth, invasion and metastasis
01/18/2000US6015892 Nucleotide sequences for diagnosis and treatment of related disorders; antisense/anticarcinogenic/antitumor agents; antiinflammatory/antiproliferative agents
01/18/2000US6015889 Protein rib, a cell surface protein that confers immunity to many strains of the group B streptococcus: process for purification of the protein, reagent kit and pharmaceutical composition
01/18/2000US6015886 Antisense agents with modifications including p-alkoxy and 2'-o-methyl groups; nuclease resistant, ability to activate bacterial ribonuclease h, form stable duplexes with rna, and have strong hydrophobicity for efficient cellular uptake
01/18/2000US6015880 Solid phase synthesis by applying liquid reagents at various locations using one jet of multijet dispenser for covalent attachment to reactive, undifferentiated matrix; repeating; washing; modifying; repeating; optionally removing compounds
01/18/2000US6015688 Transferrin receptor genes
01/18/2000US6015687 Apoptosis-modulating proteins, DNA encoding the proteins and methods of use thereof
01/18/2000US6015675 Rapid and simple analysis by adding complementary and mismatched primers to nucleic acid sample, preferentially hybridizing one primer, chain extension, detecting extension product as indication of specific sequence
01/18/2000US6015669 Identification of genes
01/18/2000US6015668 Cloned DNA polymerases from thermotoga and mutants thereof
01/18/2000US6015666 Rapid DNA test for detecting quinolone-resistant Staphylococcus aureus pathogens in clinical material
01/18/2000US6015556 Cytotoxic drug therapy
01/18/2000US6015376 DNA sequence corresponding to the minimal essential promoter of the human sodium-iodide symporter (hNIS)
01/18/2000CA2050336C Yeast processing system comprising a negatively charged amino acid adjacent to the processing site
01/18/2000CA2003500C Process for producing cdna
01/13/2000WO2000001851A1 Antisense oligonucleotides targeted to il-15
01/13/2000WO2000001819A1 Human elk, a voltage-gated potassium channel subunit
01/13/2000WO2000001711A1 Reusable solid support for oligonucleotide synthesis
01/13/2000WO2000001393A2 OLIGONUCLEOTIDE INHIBITORS OF bcl-xL
01/13/2000WO1999058118A3 METHODS FOR REGULATING HEMATOPOIESIS USING CpG-OLIGONUCLEOTIDES
01/13/2000WO1999052923A3 Method for the production of pentopyranosyl nucleosides
01/13/2000WO1999041007B1 Method and apparatus for chemical and biochemical reactions using photo-generated reagents
01/13/2000CA2336384A1 Oligonucleotide inhibitors of bcl-xl
01/13/2000CA2332699A1 Antisense oligonucleotides targeted to il-15
01/12/2000EP0970251A2 Analysis of genetic polymorphisms and gene copy number