Patents
Patents for C07H 21 - Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids (89,892)
10/1999
10/28/1999WO1999053762A1 A method for efficient and highly selective control of microorganisms
10/28/1999WO1999025724A3 Oligonucleotide synthesis using high boiling point solvents
10/28/1999CA2328967A1 A method for efficient and highly selective control of microorganisms
10/28/1999CA2328888A1 Rapidly degrading gfp-fusion proteins and methods of use
10/28/1999CA2325821A1 Antisense oligonucleotides for the inhibition of integrin .alpha.v-subunit expression
10/27/1999EP0952216A2 Solid phase supports with PNA and amidate tag compliments
10/27/1999EP0951541A1 Biomarkers and targets for diagnosis, prognosis and management of prostate disease
10/27/1999EP0853630A4 Detecting genetic predisposition to periodontal disease
10/27/1999EP0682716A4 Rna assays using rna binary probes and ribozyme ligase.
10/27/1999EP0584145B1 Process for the in vitro diagnosis of chromosomal anomalies correlated with cmt1a disease
10/27/1999CN1233181A Method of treating ciliary dyskinesia with uridine triphosphates and related compounds
10/26/1999US5973138 Method for purification and manipulation of nucleic acids using paramagnetic particles
10/26/1999US5973136 Inverted chimeric oligonucleotides
10/26/1999US5973134 Rat CNP complementary DNA and precursor protein
10/26/1999US5973132 Expression of dna coding for house dust mite allergens.
10/26/1999US5972901 Making a composition for delivering an oligonucleotide to a mammalian cell by providing a peptide target binding moiety being capable of binding to a serpin enzyme complex receptor, polylysine, an oligonucleotide vector; conjugating, coupling
10/26/1999US5972900 Conjugating target binding moiety consisting of an antibody or fragment which binds to secretory component of polymeric immunoglobulin receptor on surface of epithelium cell, nucleic acid binder, expression vector, compacting, administering
10/26/1999US5972705 Sequence-specific methylation of ribonucleic acid
10/26/1999US5972698 Tryptase is expressed virtually exclusively by mast cells.
10/26/1999US5972613 Methods of nucleic acid isolation
10/26/1999US5972611 Hybridization carrier and a process for preparing the same
10/26/1999US5972610 Use of nucleic acid analogues in the inhibition of nucleic acid amplification
10/26/1999US5972607 Methods for nucleic acid amplification with thermostable ribonuclease H
10/26/1999US5972599 High affinity nucleic acid ligands of cytokines
10/26/1999US5972597 Methods using modified vaccinia virus
10/26/1999US5972352 Cloning of mite allergens
10/26/1999US5972349 Synthesis of polyribosylribitol phosphate oligosaccharides
10/26/1999US5972338 ?tie? or ?tie? are acronyms, which stand for ?tyrosine kinase containing ig and egf homology domains?; present invention concerns novel human tie ligand homologues with powerful effects on vasculature; antitumor agents
10/26/1999US5972337 46 kilodalton human milk fat globule (HMFG) antigen, fragments and fusion protein
10/21/1999WO1999053094A1 Method for in vivo detecting target protein gene by drug
10/21/1999WO1999052956A1 Compounds and polymers formed from imidazoles
10/21/1999WO1999052929A1 Nucleic acid sequences and proteins associated with aging
10/21/1999WO1999052927A1 Non-endogenous, constitutively activated human serotonin receptors and small molecule modulators thereof
10/21/1999WO1999052925A1 Programmed cell death and caspase-12
10/21/1999WO1999052923A2 Method for the production of pentopyranosyl nucleosides
10/21/1999WO1999052541A2 Artery- and vein-specific proteins and uses therefor
10/21/1999WO1999042593A8 Compositions and methods for sensitizing and inhibiting growth of human tumor cells
10/21/1999WO1999042118A8 Compounds and methods for diagnosis of tuberculosis
10/21/1999WO1999024452A8 Pyrimidine derivatives for labeled binding partners
10/21/1999CA2402599A1 Programmed cell death and caspase-12
10/21/1999CA2328382A1 Compounds and polymers formed from imidazoles
10/21/1999CA2327516A1 Programmed cell death and caspase-12
10/21/1999CA2327436A1 Process for the preparation of pentopyranosylnucleosides
10/21/1999CA2325563A1 Artery- and vein-specific proteins and uses therefor
10/21/1999CA2325559A1 Non-endogenous, constitutively activated human serotonin receptors and small molecule modulators thereof
10/21/1999CA2323934A1 Nucleic acid sequences and proteins associated with aging
10/20/1999EP0950720A1 Methods for polymorphism identification and profiling
10/20/1999EP0950709A1 Antisense oligonucleotides for the inhibition of integrin alphaV-subunit expression
10/20/1999EP0950707A1 Homologous recombination for universal donor cells and chimeric mammalian hosts
10/20/1999EP0950112A1 Photolabile polymer array synthesis methods
10/20/1999EP0766689B1 Novel oligosaccharide derivatives, preparation method therefor and uses thereof
10/20/1999CN1232505A Nucleic acid sequences that encode cell growth regulatory protein and uses thereof
10/20/1999CN1232467A Isolated nucleic acid molecule encoding cancer associated antigen, antigen itself, and uses thereof
10/19/1999US5969129 Purification of polynucleotides from polynucleotide/polysaccharide mixtures
10/19/1999US5969128 Nucleic acid probes with terminal primary amine groups in a configuration for attachment of marker which is detectable by production of color or light; diagnosis of genetic disorders, oncogenes, viral/bacteria/parasitic diseases
10/19/1999US5969120 Dna molecule with synthetically mutated retinoblastoma gene encoding a mutated protein; therapy for a tumor cell with mutation in cyclin gene; antitumor agents
10/19/1999US5969119 Sequencing based on repeated cycles of duplex extension along a single stranded template; oligonucleotide probes having a blocking moiety in a terminal position so that only a single extension of the extended duplex occurs in a single cycle
10/19/1999US5969118 Backbone modified oligonucleotide analogs and preparation thereof through radical coupling
10/19/1999US5969117 Modified protein kinase a-specific oligonucleotide
10/19/1999US5969116 Ribo-nucleoside analogues the 2'-oh group etherified, and having a radical forming a phosphorous or ether-containing nucleotide bridge group, capable of base pairing with a complementary nucleic acid strand; binding affinity
10/19/1999US5969111 Radiation sensistizers
10/19/1999US5969110 Antibodies which are immunoreactive with a human tyrosine kinase ligand protein
10/19/1999US5969108 Methods for producing members of specific binding pairs
10/19/1999US5968909 Method of modulating gene expression with reduced immunostimulatory response
10/19/1999US5968826 Antisense inhibition of integrin α4 expression
10/19/1999US5968825 Antisense oligonucleotides complementary to the primary transcript of the human c-fes protooncogene
10/19/1999US5968821 Adenovirus vector containing nucleotide sequence coding polypeptide which binds and inhibits cyclin kinase; screening for agonist or antagonist to cell propagation; develop immunogen; antitumor agents; diagnostic model for disease
10/19/1999US5968819 DNA encoding a hypothalamic atypical neuropeptide Y/peptide YY receptor (Y5)
10/19/1999US5968818 Nucleic acid coding an enzyme whose presence can be used to acess sensitivity to atherosclerosis
10/19/1999US5968805 Polyester synthase and a gene coding for the same
10/19/1999US5968754 Detecting the presence of breast cancer proteins in humans; screening for breast cancer by measuring diagnostic marker for breast cancer in sample
10/19/1999US5968736 Methods for recording the reaction history of a solid support
10/19/1999CA2119974C Human cell adhesion molecule and nucleic acid sequences
10/19/1999CA1340796C Antisense oligonucleotide antibiotics complementary to the macromolecular synthesis operon, methods of treating bacterial infections, and methods for identification of bacteria
10/17/1999CA2268457A1 Mammalian rad1 genes, polypeptides and methods of use
10/14/1999WO1999051773A1 Addressable protein arrays
10/14/1999WO1999051735A2 Mapkap kinase 2-inhibitors and the use thereof in anti-inflammatory therapy
10/14/1999WO1999051734A1 Glass microfiber column and method for the preparation and purification of plasmid dna using the same
10/14/1999WO1999051732A1 Secreted proteins and polynucleotides encoding them
10/14/1999WO1999051621A2 Hybridization and mismatch discrimination using oligonucleotides conjugated to minor groove binders
10/14/1999WO1999051547A2 Solid phase synthesis of organic compounds via phosphitylating reagents
10/14/1999WO1999051274A1 Polyene macrolide derivatives, use for vectoring molecules
10/14/1999WO1999036544A3 Neisseria meningitidis antigens
10/14/1999WO1999028462A3 Polypeptides and nucleic acids encoding the same
10/14/1999WO1999010486A3 Mdm2-specific antisense oligonucleotides
10/14/1999DE19815901A1 Verfahren zur Herstellung von Pentopyranosyl-Nucleosiden A process for preparing pentopyranosylnucleosides
10/14/1999CA2329135A1 Hybridization and mismatch discrimination using oligonucleotides conjugated to minor groove binders
10/14/1999CA2327737A1 Polyene macrolide derivatives, use for vectoring molecules
10/14/1999CA2324984A1 Secreted proteins and polynucleotides encoding them
10/14/1999CA2323638A1 Addressable protein arrays
10/13/1999EP0948542A1 Small and intermediate conductance, calcium-activated potassium channels and uses thereof
10/13/1999EP0948518A1 Isolated nucleic acid molecule encoding cancer associated antigen, the antigen itself, and uses thereof
10/13/1999EP0948514A1 Method for the synthesis of nucleotide or oligonucleotide phosphoramidites
10/13/1999EP0948512A1 Method of synthesizing phosphorothioate oligonucleotides
10/13/1999EP0948511A2 Chemical synthesis of nucleosides analogs and their incorporation into polynucleotides
10/13/1999EP0948510A1 Immunostimulatory nucleic acid molecules
10/13/1999EP0850300B1 Method of modulating gene expression with reduced immunostimulatory response
10/13/1999CN1045620C Process for preparing DNA construction with preceding sequence of kluyveromyces X-factor directing heterologous polypeptide excretion
10/13/1999CN1045539C CDNA clones coding for polypeptides exhibiting human granulocyte macrophage and eosinophie cellular growth
10/12/1999US5965791 Vector for introducing a gene into a plant, and methods for producing transgenic plants and multitudinously introducing genes into a plant using the vector