Patents
Patents for C07H 21 - Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids (89,892)
10/1999
10/12/1999US5965725 Polypeptides, and preparation and DNA encoding thereof
10/12/1999US5965722 Oligonucleotide with methylene(methylimino) linkages alternating with phosphorothioate or phosphodiester linkages; with increased nuclease resistance, stability, affinity for messenger rna; anticarcinogenic/antiarrhythmia agents
10/12/1999US5965721 With improved nuclease resistance and improved cellular uptake; for antisense agents and regulation of rna expression
10/12/1999US5965720 With sequence complementary to messenger rna from a gene selected from the group consisting of c-myc, c-myb, c-fos, c-kit, ras and bcr/abl; antisense/anticarcinogenic agents
10/12/1999US5965695 Modified peptide and peptide libraries with protease resistance, derivatives thereof and methods of producing and screening such
10/12/1999US5965417 Arabidepsi thaliana proteins having Δ-5,7-sterol-Δ-7-reductase activity
10/12/1999US5965390 Protein L and hybrid proteins thereof
10/12/1999US5965364 Method for selecting functional deoxyribonucleotide derivatives
10/12/1999US5965360 Diagnosis of metastatic cancer by the mts-1 gene
10/12/1999US5965359 Mixing cells from biological sample with detectable labeled complementary dna probe, detecting the presence of the probe that hybridizes with messenger rna for human platelet-derived growth factor receptor gene
10/12/1999US5965133 Self-assembling multimeric nucleic acid constructs
10/12/1999US5965129 Purified cathepsin polypeptide and amino acid sequence or immunologically active fragments thereof; administering the novel protein with a pharmaceutical carrier to treat cancer
10/07/1999WO1999050461A1 Therapeutic and diagnostic applications based on the role of the cxcr-4 gene in tumorigenesis
10/07/1999WO1999050441A1 A selective assay for determining the identity of live microorganisms in a mixed culture
10/07/1999WO1999050278A1 Compositions and methods for the identification of lung tumor cells
10/07/1999WO1999039174A3 An automatic method of classifying molecules
10/07/1999DE19814963A1 MAPKAP Kinase 2-Hemmer und ihre Verwendung für die anti-inflammatorische Therapie MAPKAP kinase 2 inhibitors and their use for the anti-inflammatory therapy
10/07/1999CA2735260A1 Methods for the diagnosis and treatment of lung cancer by detection of proto-oncogene overexpression
10/07/1999CA2731416A1 Therapeutic and diagnostic applications based on the role of the cxcr-4 gene in tumorigenesis
10/07/1999CA2325851A1 An assay for determining the identity and replication ability of a microorganism utilizing a nucleic acid analog
10/07/1999CA2323833A1 Compositions and methods for the identification of lung tumor cells
10/06/1999EP0947583A2 DNA fragments activated in expression of melanoma inhibiting protein (MIA)
10/06/1999EP0947246A1 Substrate for array printing
10/06/1999EP0946582A1 Solvent vehicles for reagent delivery in oligonucleotide synthesis using automated pulse jetting devices
10/06/1999EP0946286A1 Chemical amplification for the synthesis of patterned arrays
10/06/1999EP0946201A1 Agent and method of treatment for diseases and conditions associated with respiratory ailments and lung inflammation
10/06/1999EP0838025A4 Self-contained device integrating nucleic acid extraction, amplification and detection
10/06/1999EP0779933A4 Methods for producing antibody libraries using universal or randomized immunoglobulin light chains
10/06/1999CN1230998A Three component chimeric antisense oligonucleotides
10/06/1999CN1045448C Using seryl histidine, phosphorylated serine, phosphorylated threonine as nucleic chipping agent
10/05/1999US5962674 Nucleoside monomer for use in solid phase synthesis; has protecting group of n-pent-4-enoyl which is stable under synthesis conditions but can be removed under mild conditions; for antisense agents, investigation of genes
10/05/1999US5962669 Nucleic acid encoding prion protein variant
10/05/1999US5962648 Human procollagen or collagen produced in this manner can be made of a single collagen type uncontaminated by other human or non-human collagens.
10/05/1999US5962431 Method of treating papillomavirus using 2',5'-oligoadenylate
10/05/1999US5962426 Hybrid
10/05/1999US5962425 Hydridizing oligonucleotide
10/05/1999US5962411 Human growth hormone variants and methods of administering same
10/05/1999US5962320 Engineered antigen presenting cells and methods for their use
10/05/1999US5962316 Cell-cycle regulatory proteins, and uses related thereto
10/05/1999US5962310 Vehicle for delivery of particles to a sample
10/05/1999US5962298 Influenza vaccine
10/05/1999US5962294 Compositions and methods for the identification and synthesis of sialyltransferases
10/05/1999US5962269 Methods for producing antibodies which specifically bind to interleukin-9 receptor
10/05/1999US5962267 Proinsulin derivative and process for producing human insulin
10/05/1999US5962260 Recombinant production of human and bovine receptors for modified low-density lipoprotein
10/05/1999US5962258 Carboxymethyl cellulase fromthermotoga maritima
10/05/1999US5962256 Nuclear thyroid hormone receptor-interacting polynucleotides and related molecules and methods
10/05/1999US5962246 Isolated protein which is deoxyuridine triphosphatase, an enzyme important in cell proliferation; for use as marker to give accurate information about the status of cells or tissues
10/05/1999US5962225 The present invention can be performed on large amounts of purified dna in a single test, with high levels of sensitivity, thus eliminating the need for dna amplification procedures.
10/05/1999US5962219 Systematic evolution of ligands by exponential enrichment: chemi-selex
10/05/1999US5962217 MSRV1 virus and MSRV2 pathogen and/or infective agent associated with multiple sclerosis, and biopolymer constituents thereof
10/05/1999US5961923 The matrix materials are those that are used in as supports in solid phase chemical and biochemical syntheses, immunoassays and hybridization reactions.
09/1999
09/30/1999WO1999049319A1 Micro system and method for field manipulation of particles
09/30/1999WO1999049067A1 Nucleic acid transfer vectors, compositions containing same and uses
09/30/1999WO1999049065A1 Antisense modulation of human mdm2 expression
09/30/1999WO1999049020A2 Phenol oxidizing enzyme enzymes
09/30/1999WO1999048904A1 HIGH AFFINITY TGFβ NUCLEIC ACID LIGANDS AND INHIBITORS
09/30/1999WO1999037788A3 Diagnosis and treatment of aur1 and/or aur2 related disorders
09/30/1999WO1999032149A9 GENES FOR MALE ACCESSORY GLAND PROTEINS IN $i(DROSOPHILA MELANOGASTER)
09/30/1999DE19913864A1 DNA fragments useful for increasing p53 activity in a cell and reducing susceptibility to UV-induced hyperproliferative diseases
09/30/1999CA2323831A1 Nucleic acid transfer vectors, compositions containing same and uses
09/30/1999CA2322773A1 Antisense modulation of human mdm2 expression
09/30/1999CA2322661A1 Phenol oxidizing enzyme enzymes
09/29/1999EP0944642A1 Dioxetane labeled probes and detection assays employing the same
09/29/1999EP0944641A1 Non-helical supramolecular nanosystems
09/29/1999CN1230228A Methods for judging possibility of onset of bovine leukemia and resistance thereto
09/29/1999CN1230227A Prolactin receptor gene as genetic marker for increased litter size in pigs
09/28/1999US5959183 Cytoplasmic male sterility DNA factor and utilization thereof
09/28/1999US5959176 Plant promoter and utilization thereof
09/28/1999US5959099 Protecting group for synthesizing oligonucleotide analogs
09/28/1999US5959098 Activating and coupling monomers in different selected zones of substrate forming different sequences in different areas; activating by directing radiation at surface of substrate with functional groups protected by photolabile groups
09/28/1999US5959096 For anticarcinogenic/antitumor/antiproliferative agents; antiinflammatory agents; treatment of psoriasis, and glioblastoma, bladder, breast, lung and tumor cancer
09/28/1999US5959095 Amplification of midivariant DNA templates
09/28/1999US5959090 Chemical phosphorylation of oligonucleotides and reactants used therefor
09/28/1999US5958891 Administering vector comprising gene encoding dust mite allergen by intramuscular injection to prevent airway hyperreactivity or airway inflammation
09/28/1999US5958734 Isolated polynucleotides and polypeptides of the glutamyl trna synthetase family (glus), vectors encoding them, host cells and methods for their production; use to screen for novel antibiotics
09/28/1999US5958718 Diagnosis and treatment of neuro-cognitive disorders associated with systemic immunological malfunction
09/28/1999US5958709 Processes for identifying compounds that bind to the human Y4 receptor
09/28/1999US5958697 Isolated nucleic acids encoding CYP7 promoter-binding factors
09/28/1999US5958691 High affinity nucleic acid ligands containing modified nucleotides
09/28/1999US5958682 Virus-directed enzyme prodrug therapy for treating tumor cells consisting of a viral vector encoding bacterial nitroreductase capable of converting a prodrug into a cytotoxic drug operably linked to a promoter; and the prodrug
09/28/1999US5958681 Stabilizing a complex of polynucleotide sequence and a partially complementary and single stranded displacer sequence
09/28/1999US5958424 Recombinant chicken anemia virus particle
09/28/1999US5958400 Isolated polypeptide comprising specified amino acid sequence
09/28/1999CA2076678C Improved chimeric toxins
09/28/1999CA1340775C Method for detection of specific nucleic acid sequences
09/28/1999CA1340764C Octopine t-dna promoters
09/23/1999WO1999047923A2 Assays for screening compounds which interact with cation channel proteins, mutant prokaryotic cation channel proteins, and uses thereof
09/23/1999WO1999047707A1 Antisense modulation of lfa-3
09/23/1999WO1999047683A1 Gene encoding labyrinthin, a marker for cancer
09/23/1999WO1999047535A1 METHODS AND COMPOSITIONS FOR DIAGNOSING AND TREATING CHROMOSOME-18p RELATED DISORDERS
09/23/1999WO1999047169A1 Methods to provoke anti-cancer immune responses
09/23/1999WO1999046988A1 Compositions and methods for antigen-specific vaccination
09/23/1999WO1999041273A3 Pna and dna conjugates and methods for preparation thereof
09/23/1999WO1999038874A3 Electrophoretic nucleic acid purification method
09/23/1999WO1999032620A9 Insulin-like growth factor binding protein fragments and the utilization thereof
09/23/1999WO1999027944A9 Prevention and treatment of amyloidogenic disease
09/23/1999CA2323830A1 Methods and compositions for diagnosing and treating chromosome-18p related disorders
09/23/1999CA2323725A1 Assays for screening compounds which interact with cation channel proteins, mutant prokaryotic cation channel proteins, and uses thereof
09/23/1999CA2323494A1 Gene encoding labyrinthin, a marker for cancer