Patents
Patents for C07H 21 - Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids (89,892)
02/1999
02/16/1999US5871996 First agent comprising isolated virus having reverse transcriptase activity, second agent distinct from first, comprising nucleotides; both agents associated with multiple sclerosis and purifiable from viral isolate pol-2 and ms7pg
02/16/1999US5871984 Compounds and methods for site directed mutations in eukaryotic cells
02/16/1999US5871934 Screening methods using cytokine suppressive anti-inflammatory drug (CSAID) binding proteins
02/16/1999US5871928 Methods for nucleic acid analysis
02/16/1999US5871913 Forms a complex with a human immunodeficiency virus envelope glycoprotein
02/16/1999US5871911 Annealing target and pilot nucleic acids to form duplex; exposing to polymerase; genetic engineering
02/16/1999US5871745 Isolated virus having reverse transcriptase activity, second agent distinct from first, comprising nucleotides; both agents associated with multiple sclerosis and purifiable from viral isolate pol-2 and ms7pg
02/16/1999US5871729 Superoxide dismutase-4
02/16/1999CA2000913C Family of high affinity antibodies for cancer treatment
02/11/1999WO1999006595A1 Dendritic nucleic acids exhibiting maximal self-assembly
02/11/1999WO1999006593A1 Solid support with attached molecules
02/11/1999WO1999006425A1 Oxidized styrenic polymers for dna binding
02/11/1999WO1999006422A2 Base analogues
02/11/1999WO1998050397A3 Chimeric oligonucleotides and the use thereof
02/11/1999WO1998046771A3 Highly purified mocarhagin, a cobra venom protease, polynucleotides encoding same, related proteases, and therapeutic uses thereof
02/11/1999CA2298061A1 Polynucleotide compositions
02/11/1999CA2297776A1 Base analogues
02/11/1999CA2297745A1 Oxidized styrenic polymers for dna binding
02/11/1999CA2296038A1 Solid support with attached molecules
02/10/1999EP0896055A2 Apoptosis inducing protein and gene encoding the same
02/10/1999EP0763133A4 Method for detecting a target nucleic acid
02/10/1999CN1207394A Method for extracting chicken nucleic acid and nucleoprotein from chicken blood
02/09/1999US5869715 Cationic monoamine compound (quaternary ammonium or tertiary amine salt with 2 halogenated aliphatic groups and 2 ethers or esters) for transporting biologically active species through membrane barriers; nonviral
02/09/1999US5869696 Universal solid supports and methods for their use
02/09/1999US5869666 4',6'-cyclopropane-fused carboxylic nucleoside analogs in which the oxygen in the ribose ring is substituted for carbon; antimetabolites; locking dna in solution to examine dna-protein, dna-rna and dna-dna interactions
02/09/1999US5869643 Process for preparing polynucleotides on a solid support in a tightly packed bed
02/09/1999US5869641 An isolated modified rna ligand that reacts like an anti-cd4 antibody; treating autoimmune diseases, hiv, antidiabetic and antiarthritic agents
02/09/1999US5869636 Recombinant cell line expressing polypetide for anticarcinogenic and antitumor agents and vaccines
02/09/1999US5869631 A newly isolated human immunodeficiency virus capable of causing aids; having genetic polymorphism with variablility in the envelope region and glycosylation; detection and diagnosis of aids
02/09/1999US5869612 Amino acid sequence of isolated protein involved in post-receptor signal transduction; treatment of rheumatoid arthritis and septic shock
02/09/1999US5869298 Stable mutants of D-N-α-carbamoylase and process for preparing D-α-amino acids
02/09/1999US5869284 Polynucleotide for gene expression in cultures; for tissue regeneration, stimulation of immune and hematopoeitic systems, modulators of receptor activity
02/09/1999US5869265 Screening modulators by contacting recombinant cells which express cotransporter with substance, determining increase or decrease in activity; anticholesterol agents; antidiabetic agents; liver disease; crohn's disease
02/09/1999US5869254 In vitro splicing non-viral target nucleic acid with another to correct defect; for gene therapy, viricides
02/09/1999US5869253 Enzymatic ribozyme molecule having a substrate binding site and an active site that cleaves hepatitis c virus rna; diagnosis and viricides
02/09/1999US5869248 Targeted cleavage of RNA using ribonuclease P targeting and cleavage sequences
02/09/1999US5869246 Triplex Oligonucleotides targeted to p120
02/09/1999US5869236 Detecting mutations in nucleic acid sample by subjecting double-stranded hybrid stabilized by covalent photobridging with photoactivatable intercalating agent to denaturing gradient gel electrophoresis and comparing to control
02/09/1999US5869235 Dna coding for the coat protein of virus isolated from infected vine plants; for detection of vrial infection by reverse transcription polymerase chain reaction and southern blotting
02/09/1999CA1340388C Restriction lenght polymorphism test for haplotyping domesticated fowl
02/09/1999CA1340384C Methode d'utilisation de vecteurs d'expression eucaryotes comprenant un amplificateur du virus bk
02/09/1999CA1340382C Process for the preparation of 2-arylpropionic acids
02/09/1999CA1340381C Recombinant fusion proteins
02/04/1999WO1999005322A1 Computer method and system for correlating sequencing data by ms
02/04/1999WO1999005319A2 Methods and compounds for analyzing nucleic acids by mass spectrometry
02/04/1999WO1999005303A1 Preparation of lipid-nucleic acid particles using a solvent extraction and direct hydration method
02/04/1999WO1999005277A1 A recombinant expression vector of human parathyroid hormone using phosphoribulokinase as a fusion partner
02/04/1999WO1999005275A1 Secreted proteins encoded by human chromosome 13
02/04/1999WO1999005160A2 Oligonuclotides having 3' terminal stereospecific phosphorothioates
02/04/1999WO1999005155A2 Salts of di(uridine 5'-tetraphosphate), method for preparation and uses thereof
02/04/1999WO1999004775A2 Method of treating dopaminergic and gaba-nergic disorders
02/04/1999WO1999004626A1 Novel gene encoding a dna repair endonuclease and methods of use thereof
02/04/1999WO1999004622A1 Transgenic plants with tocopherol methyltransferase
02/04/1999WO1998049182A3 Gggg or gtgt as carriers for drug delivery
02/04/1999CA2298980A1 Novel gene encoding a dna repair endonuclease and methods of use thereof
02/04/1999CA2298117A1 Computer method and system for correlating sequencing data by ms
02/04/1999CA2298050A1 Transgenic plants with tocopherol methyltransferase
02/04/1999CA2297410A1 Method of treating dopaminergic and gaba-nergic disorders
02/04/1999CA2296292A1 Secreted proteins encoded by human chromosome 13
02/03/1999EP0895082A2 Method of spotting probe on solid support, probe array and method of manufacturing thereof, and method of detecting target substance and method of identifying structure of target substance using probe array
02/03/1999EP0894865A2 Chimeric herbicide resistance gene
02/03/1999EP0894096A1 An assay system and novel labelled compounds for use therewith
02/03/1999EP0669897B1 Separation of nucleic acid fragments
02/03/1999CN1207137A Double-stranded conformational polymorphism analysis
02/03/1999CN1207126A Ligand polypeptides for the G-protein-coupled receptor protein, their production and use
02/03/1999CN1207124A Recombinant sendal virus
02/03/1999CN1206714A Oligomeric deoxynucleotide of vascular endothelial cell growth factor
02/02/1999US5866793 Promoter for expressing foreign genes in monocotyledonous plants
02/02/1999US5866779 Recombinant gibberellin DNA and uses thereof
02/02/1999US5866700 Solid-phase synthesis of oligoribonucleotides
02/02/1999US5866699 Oligonucleotides with anti-MDR-1 gene activity
02/02/1999US5866686 Nuclear thyroid hormone receptor-interacting polypeptides and related molecules and methods
02/02/1999US5866553 Immune protection against infection
02/02/1999US5866550 Method of inhibiting replication of hyperproliferative cells using a nucleic acid encoding EIA
02/02/1999US5866374 Gene conferring flocculating property on yeast and gene product thereof
02/02/1999US5866361 Vectors are useful in gene mapping and site-directed insertion of genes.
02/02/1999US5866334 Determination and identification of active compounds in a compound library
02/02/1999US5866333 Screening methods to detect mRNA targets of editing enzymes
02/02/1999US5866129 Method of producing an antibody with a peptide corresponding to membrane-bound IgA
02/02/1999US5866126 Complexing
02/02/1999CA1340371C Methods and products for facile microbial expression of dna sequences
02/02/1999CA1340369C Antisense oligonucleotides to c-myb proto-oncogene and uses thereof
02/01/1999CA2244403A1 Method of spotting probe on solid support, probe array and method of manufacturing thereof, and method of detecting target substance and method of identifying structure of target substance using probe array
01/1999
01/28/1999WO1999004041A1 Methods and compositions for modulating melting temperatures of nucleic acids
01/28/1999WO1999004040A1 Methods for diagnosis and treating cancers, and methods for identifying pathogenic markers in a sample of normal cells
01/28/1999WO1999003886A1 Tropoelastin derivatives
01/28/1999WO1999003873A2 Novel sulfurizing reagent 3-phenyl-1,2,4-dithiazoline-5-one
01/28/1999WO1999003849A1 Fluorescent dibenzazole derivatives and methods related thereto
01/28/1999WO1998038324A3 Chimeric cell-surface receptors that undergo antigen-induced association
01/28/1999DE19720165A1 Production of polymeric compounds with nucleo-base substituent(s)
01/28/1999CA2295926A1 Methods for diagnosis and treating cancers, and methods for identifying pathogenic markers in a sample of normal cells
01/28/1999CA2295304A1 Fluorescent dibenzazole derivatives and methods related thereto
01/27/1999EP0892808A1 Detection probes, kits and assays
01/27/1999EP0777675B1 Solid support reagents for the synthesis of 3'-nitrogen containing polynucleotides
01/27/1999EP0658198B1 Multicistronic expression units and their use
01/27/1999EP0542770B1 Random bio-oligomer library, a method of synthesis thereof, and a method of use thereof
01/27/1999EP0461177B1 Human intra-acrosomal sperm antigen for use in a contraceptive vaccine
01/26/1999US5864032 Biotin derivative of an 2-(n,n-diisopropyl-o-nitrilopropyl-phosphoramidito),3-(3-aminopropyl) -glycerol; labels for synthetic oligonucleotides; hybridisation probes
01/26/1999US5864031 Process for preparing 5-dithio-modified oligonucleotides
01/26/1999US5864026 Systematic evolution of ligands by exponential enrichment: tissue selex