Patents
Patents for C07H 21 - Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids (89,892)
05/1999
05/18/1999CA2187250C Method for producing a soluble protein with bacteria
05/18/1999CA1340544C Human tissue factor related dna segments, polypeptides and antibodies
05/18/1999CA1340542C Molecular cloning and characterization of a gene sequence coding for human relaxin
05/14/1999WO1999023257A1 Method of detecting mutant dna by mipc and pcr
05/14/1999WO1999023108A1 Inducible phosphofructokinase and the warburg effect
05/14/1999WO1999022868A1 Pressure-enhanced extraction and purification
05/14/1999WO1999022772A1 LIPOSOMAL OLIGONUCLEOTIDE COMPOSITIONS FOR MODULATING ras GENE EXPRESSION
05/14/1999WO1999022742A1 Rnase l activators and antisense oligonucleotides effective to treat rsv infections
05/14/1999WO1999010365A3 5',5'-linked oligomers having anti-thrombin activity
05/14/1999WO1999005319A3 Methods and compounds for analyzing nucleic acids by mass spectrometry
05/14/1999WO1998051697A3 Method for producing polymers having nucleo-bases as side-groups
05/14/1999WO1998033904A3 An antisense oligonucleotide preparation method
05/14/1999CA2308852A1 Rnase l activators and antisense oligonucleotides effective to treat rsv infections
05/14/1999CA2308091A1 Inducible phosphofructokinase and the warburg effect
05/14/1999CA2307876A1 Pressure-enhanced extraction and purification
05/12/1999EP0915163A1 GENE ENCODING $g(b)-GALACTOSIDE $g(a)-2,6-SIALYLTRANSFERASE
05/12/1999EP0915153A1 $g(b)-GALACTOSIDE $G(a)-2,6-SIALYLTRANSFERASE
05/12/1999EP0914443A2 Use of a modified rev-responsive element (rre) in methods and compositions for combatting hiv infection
05/12/1999EP0914431A2 Truncated soluble tumor necrosis factor type-i and type-ii receptors
05/12/1999EP0914422A1 Mammalian genes involved in viral infection and tumor suppression
05/12/1999EP0914421A2 Hepatitis c virus ribozymes
05/12/1999EP0914324A2 Specific inhibitors of dna methyltransferase enzyme
05/12/1999EP0883692A4 Methods for producing and analyzing biopolymer ladders
05/12/1999EP0648280B1 Method and reagent for determining specific nucleotide variations
05/12/1999EP0446245B1 Electrochemiluminescent assays
05/11/1999US5902881 Reagent useful for synthesizing sulfurized oligonucleotide analogs
05/11/1999US5902880 RNA polymerase III-based expression of therapeutic RNAs
05/11/1999US5902879 Methoxyoxalamido and succinimido precursors for nucleophilic addition to nucleosides, nucleotides and oligonucleotides
05/11/1999US5902878 Modified phosphoramidite process for the production of modified nucleic acids
05/11/1999US5902723 Selectively removing a nucleotide by cleavage at terminal ends with catalytic antibodies; identifying excision site and repeating process; for concurrent parallel sequence analysis
05/07/1999CA2228977A1 Localized oligonucleotide therapy for preventing restenosis
05/06/1999WO1999022021A1 Method for isolating and purifying nucleic acids on surfaces
05/06/1999WO1999022020A2 Labelling of polymers and sequencing of nucleic acids
05/06/1999WO1999021998A1 Wnt-1 induced secreted polypeptides: wisp-1, -2 and -3
05/06/1999WO1999021874A1 Oligodeoxyribonucleotides containing modified nucleoside and the like
05/06/1999WO1999021873A2 Synthesis of polynucleotides having random sequences
05/06/1999WO1999014341A3 Proteases from gram-positive organisms
05/06/1999WO1999011813A3 Oligonucleotide probes bearing quenchable fluorescent labels, and methods of use thereof
05/06/1999WO1999009045A9 Antisense and antigene therapeutics with improved binding properties and methods for their use
05/06/1999WO1999009042A3 Microstructures for the manipulation of fluid samples
05/06/1999WO1999009041A3 Solution phase synthesis of oligonucleotides
05/06/1999WO1998042860A9 Polymerase enhancing factor (pef) extracts, pef protein complexes, isolated pef protein, and methods for purifying and identifying
05/06/1999EP0912767A2 Methods for detecting and amplifying nucleic acid sequences using modified oligonucleotides having increased target specific t m?
05/06/1999EP0912595A1 Hodgkin's disease associated molecules and uses thereof
05/06/1999EP0912594A1 Identification of essential survival genes
05/06/1999EP0912593A2 Conjugates of an oligonucleotide/electronic conductor polymer with a molecule of interest, and their uses
05/06/1999EP0912592A1 Phosphotriester oligonucleotides, amidites and method of preparation
05/06/1999EP0912470A1 Method and device for purifying and enriching molecules
05/06/1999EP0721457B1 2',5'-OLIGOADENYLATE-2',3'-CYCLOPHOSPHATES and 2',5'-OLIGOADENYLATES with antipapilloma virus activity
05/06/1999EP0674650A4 Nucleic acid probes for lactobacillus detection.
05/06/1999CA2712809A1 Kcnq2 and kcnq3-potassium channel genes which are mutated in benign familial neonatal convulsions (bfnc) and other epilepsies
05/06/1999CA2306183A1 Wnt-1 induced secreted polypeptides: wisp-1, -2 and -3
05/06/1999CA2305995A1 Labelling of polymers and sequencing of nucleic acids
05/05/1999CN1215994A Rnase L activators and antisense oligonucleotides effective to treat RSV infections
05/05/1999CN1215755A Method of introducing predetermined alteration in target sequence of genome of cell having nucleus
05/04/1999US5900481 Bead linkers for immobilizing nucleic acids to solid supports
05/04/1999US5900407 Method of treating dry eye disease with uridine triphosphates and related compounds
05/04/1999CA2166850C Vectors and use thereof for capturing target genes
04/1999
04/29/1999WO1999020774A2 NOVEL MODIFIED MSP-1 NUCLEIC ACID SEQUENCES AND METHODS FOR INCREASING mRNA LEVELS AND PROTEIN EXPRESSION IN CELL SYSTEMS
04/29/1999WO1999020766A2 NOVEL MODIFIED NUCLEIC ACID SEQUENCES AND METHODS FOR INCREASING mRNA LEVELS AND PROTEIN EXPRESSION IN CELL SYSTEMS
04/29/1999WO1999020641A1 New triplex forming oligonucleotides and their use in anti-hbv
04/29/1999WO1999020640A2 High surface density covalent immobilization of oligonucleotide monolayers
04/29/1999WO1999020298A1 Regulation of epithelial tissue by hedgehog-like polypeptides, and formulations and uses related thereto
04/29/1999WO1999004775A9 Method of treating dopaminergic and gaba-nergic disorders
04/29/1999DE19746874A1 Isolation of nucleic acids
04/29/1999CA2307322A1 Regulation of epithelial tissue by hedgehog-like polypeptides, and formulations and uses related thereto
04/29/1999CA2306799A1 Novel modified nucleic acid sequences and methods for increasing mrna levels and protein expression in cell systems
04/29/1999CA2306796A1 Novel modified msp-1 nucleic acid sequences and methods for increasing mrna levels and protein expression in cell systems
04/29/1999CA2306631A1 High surface density covalent immobilization of oligonucleotide monolayers
04/28/1999EP0911413A2 Minimal adenovirus-based gene therapy vector
04/28/1999EP0910670A1 Covalent attachment of nucleic acid molecules onto solid-phases via disulfide bonds
04/28/1999EP0910634A2 ANTISENSE INHIBITORS OF VASCULAR ENDOTHELIAL GROWTH FACTOR (VEgF/VPF) EXPRESSION
04/28/1999EP0910570A1 Integrated nucleic acid hybridization devices based upon active surface chemistry
04/28/1999EP0910569A1 Extracellular/epidermal growth factor-like protein
04/28/1999EP0910467A1 Electrochemical solid phase synthesis of polymers
04/28/1999EP0789705A4 Sequence encoding mammalian sulfonylurea receptor and method of detecting persistent hyperinsulinemic hypoglycemia of infancy
04/28/1999EP0775150B1 Endotoxin reduction or removal process
04/28/1999EP0672191A4 Quantitative detection of macromolecules with fluorescent oligonucleotides.
04/28/1999EP0637342B1 Process for typing of hcv isolates
04/28/1999EP0456766B1 TYPE oc PLATELET-DERIVED GROWTH FACTOR RECEPTOR GENE
04/28/1999CN1215058A Novel trichain formed eliyonucleotide structure and application to anti-virus of hepatitis B
04/27/1999US5898031 Oligoribonucleotides for cleaving RNA
04/27/1999CA2083826C Protein having cytokine type activity, recombinant dna coding for this protein, transformed cells and microorganisms
04/22/1999WO1999019514A1 Modifying double stranded dna to enhance separations by matched ion polynucleotide chromatography
04/22/1999WO1999019511A1 In situ and in vitro hybridization method and buffer
04/22/1999WO1999019510A1 Surface-bound, double-stranded dna protein arrays
04/22/1999WO1999019474A1 Modified oligodeoxyribonucleotides having tggg sequence
04/22/1999WO1999019359A1 Cellular receptor for hiv-1 vpr essential for g2/m phase transition of the cell cycle
04/22/1999WO1999019341A1 Replica amplification of nucleic acid arrays
04/22/1999WO1999019340A1 Improved synthesis of sulfurized oligonucleotides
04/22/1999WO1999019339A1 53 human secreted proteins
04/22/1999WO1999019338A1 Inhibitors of nucleoside metabolism
04/22/1999WO1999013886B1 Multiple target hybridizing nucleic acids, their preparation, compositions, formulation, kits and applications
04/22/1999WO1998048837A9 Polyalkylene oxide-modified single chain polypeptides
04/22/1999CA2309760A1 Modifying double stranded dna to enhance separations by matched ion polynucleotide chromatography
04/22/1999CA2306440A1 Cellular receptor for hiv-1 vpr essential for g2/m phase transition of the cell cycle
04/22/1999CA2305690A1 53 human secreted proteins
04/22/1999CA2305449A1 Replica amplification of nucleic acid arrays
04/22/1999CA2248762A1 Antisense oligodeoxynucleotides regulating expression of tnf-.alpha.
04/21/1999EP0909823A2 Detection of nucleic acids by fluorescence quenching