Patents
Patents for C07H 21 - Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids (89,892)
12/1999
12/02/1999WO1999061012A2 Therapeutic dinucleotide and derivatives
12/02/1999WO1999060855A1 Novel nucleosides having bicyclic sugar moiety
12/02/1999WO1999002544A8 Compounds having energy transfer function and method for dna base sequencing by using the same
12/02/1999DE19823876A1 Biochip comprising support bearing array of molecules, especially amino acid or nucleotide sequences
12/02/1999CA2333380A1 Novel nucleosides having bicyclic sugar moiety
12/02/1999CA2333281A1 Carotenoid ketolase genes and gene products, production of ketocarotenoids and methods of modifying carotenoids using the genes
12/02/1999CA2332540A1 Therapeutic dinucleotide and derivatives
12/01/1999EP0960947A1 Methods for judging the possibility of the onset of bovine leukemia and the resistance thereto
12/01/1999EP0960121A1 Peptide nucleic acids having enhanced binding affinity, sequence specificity and solubility
12/01/1999EP0960115A1 MAMMALIAN ADDITIONAL SEX COMBS (MAMMALIAN Asx) ACTS AS AN ONCOGENE
12/01/1999EP0665892B1 Enhanced indole biosynthesis
12/01/1999CN1046946C Method for preparing raw material of nucleic acid from natural food
11/1999
11/30/1999US5994616 Targeted synthesis of protein in mammary gland of a non-human transgenic mammal
11/30/1999US5994535 Water soluble texaphyrin metal complex preparation
11/30/1999US5994517 Homogeneous conjugate of carbohydrate ligand which binds to hepatic receptor, a bifunctional linker, and a biological stable oligonucleotide and derivative can be released from conjugate; for targeted antisense agents
11/30/1999US5994513 Oncoprotein protein kinase
11/30/1999US5994317 Quaternary cytofectins
11/30/1999US5994301 Corpuscles of stannius protein, stanniocalcin
11/30/1999US5994116 Preparing a non-infectious viral particle having defects in its replication proteins; infecting cells with the virus and a chemical inhibitor of dna synthesis, preventing viral replication and recovering the desired particles; vaccines
11/30/1999US5994113 Enzymes with aminopeptidase activity
11/30/1999US5994109 Nucleic acid transporter system and methods of use
11/30/1999US5994103 Human stanniocalcin-alpha
11/30/1999US5994095 MTS2 gene
11/30/1999US5994094 A bone morphogenetic protein; treatment of osteoporosis, prevent transplant rejection; wound healing agents; regeneration of bones, cartilage, connective tissue, skin, mucous membranes, epithelium and teeth
11/30/1999US5994082 Methods for the identification of inhibitors which suppress the activity of proteins displaying CIITA activity
11/30/1999US5994063 Substituted 4,4-difluoro-4-bora-3A,4A-diaza-s-indacene compounds for homogenous amplification/detection assays
11/30/1999US5993821 Antigens and vaccines containing said vlps that may be effective in treatment of infections caused by such viruses.
11/30/1999CA1340831C Ribozymes
11/25/1999WO1999060171A1 Compounds, screening methods, and uses involving anti-apoptotic genes and gene products
11/25/1999WO1999060169A1 Multimolecular devices, drug delivery systems and single-molecule selection
11/25/1999WO1999060167A1 Compositions and methods for topical delivery of oligonucleotides
11/25/1999WO1999060153A2 Novel g-protein coupled receptor
11/25/1999WO1999060146A1 Adeno-associated virus vectors and uses thereof
11/25/1999WO1999060012A1 Compositions and methods for non-parenteral delivery of oligonucleotides
11/25/1999WO1999060010A1 Compositions and methods for the pulmonary delivery of nucleic acids
11/25/1999WO1999060008A1 Cytosine deaminase gene
11/25/1999WO1999060007A2 Libraries of oligomers labelled with different tags
11/25/1999WO1999060005A1 Method and device for purifying nucleic acids
11/25/1999WO1999059613A1 BINDING MOIETIES FOR UROKINASE PLASMINOGEN ACTIVATOR (uPA)
11/25/1999WO1999049020A3 Phenol oxidizing enzyme enzymes
11/25/1999WO1999036429A3 Nucleobase oligomers
11/25/1999DE19822954A1 Ki-67 gene antisense oligonucleotide
11/25/1999CA2332862A1 Libraries of oligomers labelled with different tags
11/25/1999CA2329868A1 Compounds, screening methods, and uses involving anti-apoptotic genes and gene products
11/25/1999CA2329252A1 Compositions and methods for topical delivery of oligonucleotides
11/25/1999CA2329153A1 Novel g-protein coupled receptor
11/25/1999CA2329130A1 Compositions and methods for non-parenteral delivery of oligonucleotides
11/25/1999CA2328599A1 Multimolecular devices, drug delivery systems and single-molecule selection
11/25/1999CA2328596A1 Cytosine deaminase gene
11/24/1999EP0959077A1 Optically active DNA probe having phosphonic diester linkage
11/24/1999EP0958378A2 Compositions and methods for enhancing hybridization specificity
11/24/1999EP0958376A1 Prolactin receptor gene as a genetic marker for increased litter size in pigs
11/24/1999EP0958300A1 Electrokinetic sample preparation
11/24/1999EP0957929A1 Vascular endothelial growth factor (vegf) nucleic acid ligand complexes
11/24/1999EP0957926A1 Oligonucleotide compositions and methods for the modulation of the expression of b7 protein
11/24/1999EP0666864B1 Detection of a polymorphic locus
11/24/1999CN1236395A Real time homogeneous nucleotide assay
11/24/1999CN1046763C Chimeric gene for herbicidal resistance
11/23/1999US5990300 Reacting nucleoside having unprotected 3' hydroxy group with nucleoside 5'-triphosphate having 3' position protected with removable blocking moiety, in presence of enzyme which catalyzes formation of 5' to 3' phosphodiester linkage
11/23/1999US5990088 Method for treating kaposi's sarcoma with antisense oligonucleotides
11/23/1999US5989911 Site-specific synthesis of pseudouridine in RNA
11/23/1999US5989890 Compositions and methods for PACE 4 and 4.1 gene and polypeptides in cells
11/23/1999US5989882 Processes for preparing acarviosyl transferase and for using it in the conversion of acarbose homologues into acarbose, for the preparation of acarbose homologues
11/23/1999US5989881 Gene therapy, expression and engineering
11/23/1999US5989834 Contacting nonneuronal cells transfected with vector; gene expression
11/23/1999US5989823 Measuring fluorescent emission
11/23/1999US5989815 Methods for detecting predisposition to cancer at the MTS gene
11/23/1999US5989813 Detection of amplified nucleic acid sequences using bifunctional haptenization and dyed microparticles
11/23/1999US5989812 Reduced amount of abortive transcripts; genetic engineering ; rna generation
11/23/1999US5989809 Methods for detecting a polynucleotide using an inactivating reagent and composition and kit comprising same
11/23/1999US5989803 Method for treating a subject suffering from a condition associated with an extracellular zinc sphingomyelinase
11/23/1999US5989537 Methods for stimulating granulocyte/macrophage lineage using thrombopoietin
11/18/1999WO1999058723A1 Heteroduplex mutational vectors and use thereof in bacteria
11/18/1999WO1999058722A1 Characterization of interactions between molecular interaction sites of rna and ligands therefor
11/18/1999WO1999058694A1 Methods of forming protein-linked lipidic microparticles, and compositions thereof
11/18/1999WO1999058563A2 Moraxella catharralis proteins
11/18/1999WO1999058118A2 METHODS FOR REGULATING HEMATOPOIESIS USING CpG-OLIGONUCLEOTIDES
11/18/1999WO1999049319A8 Micro system and method for field manipulation of particles
11/18/1999WO1999047683A9 Gene encoding labyrinthin, a marker for cancer
11/18/1999CA2404693A1 97 human secreted proteins
11/18/1999CA2331315A1 Identification of molecular interaction sites in rna for novel drug discovery
11/18/1999CA2330741A1 Methods of forming protein-linked lipidic microparticles, and compositions thereof
11/18/1999CA2328589A1 Heteroduplex mutational vectors and use thereof in bacteria
11/18/1999CA2328406A1 Methods for regulating hematopoiesis using cpg-oligonucleotides
11/18/1999CA2328130A1 Moraxella catarrhalis proteins
11/17/1999EP0957167A1 Production of heterodimeric human fertility hormones
11/17/1999EP0956359A1 High fidelity detection of nucleic acid differences by ligase detection reaction
11/17/1999EP0956297A1 Chiral peptide nucleic acids
11/17/1999EP0956001A1 PREPARATION OF STABLE FORMULATIONS OF LIPID-NUCLEIC ACID COMPLEXES FOR EFFICIENT $i(IN VIVO) DELIVERY
11/17/1999EP0651762B1 Method and apparatus for the rapid synthesis of substrate-bound or free peptides or oligonucleotides, flat material synthesized in this way and the use of such material
11/17/1999CN1235609A Immunostimulatory nucleic acid molecules
11/17/1999CN1235594A Methods and compositions for lipidization of hydrophilic molecules
11/17/1999CN1046536C Process of reclaiming DNA fragment from agarose gel
11/16/1999US5986086 A compound conatining cyanine dye, linker and nucleoside or nucleotide
11/16/1999US5986084 Nucleoside with triple substituted silyloxymethyl group as a protection group on the 2' oxygen; protection groups are not subject to isomerization and give higher coupling yields
11/16/1999US5986083 Identifying single stranded rna target sequence and synthesizing complementary oligomer of mixed nucleosides with alternating racemic aryl- or lower alkyl-phosphonate linkages; has nuclease stability and enhanced hybridization binding
11/16/1999US5986076 A conjugate is formed by bonding a bioreactive agent to the therapeutic agent with a bond that is selectively cleavable with electromagnetic radiation; useful for controlled release of drugs to treat the disorder
11/16/1999US5986069 Human haemopoietic maturation factor polypeptides
11/16/1999US5986058 Growth differentiation factor with amino acid sequences
11/16/1999US5986053 Peptide nucleic acids complexes of two peptide nucleic acid strands and one nucleic acid strand