Patents for C07H 21 - Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids (89,892) |
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02/24/2000 | CA2333901A1 Low adenosine anti-sense oligonucleotide agent, composition, kit and treatments |
02/23/2000 | EP0980912A1 Alkaline ceramidase (E.C. 3.5.1.23) gene from Pseudomonas aeruginosa |
02/23/2000 | EP0980379A2 Chimeric oligonucleotides and the use thereof |
02/23/2000 | EP0980378A1 Method for detecting the presence of biological matters of bovine origin, and oligonucleotides for its implementation |
02/23/2000 | EP0730663A4 Arrays of nucleic acid probes on biological chips |
02/23/2000 | CN1245503A Oil bodies and associated proteins as affinity matrices |
02/23/2000 | CN1049686C Diagnostics and vaccines for hepatits virus non-A and non-B |
02/22/2000 | US6028189 Solvent for oligonucleotide synthesis and methods of use |
02/22/2000 | US6028188 Synthetic oligomers having chirally pure phosphonate internucleosidyl linkages mixed with non-phosphonate internucleosidyl linkages |
02/22/2000 | US6028186 High affinity nucleic acid ligands of cytokines |
02/22/2000 | US6028183 Pyrimidine derivatives and oligonucleotides containing same |
02/22/2000 | US6028182 Methylphosphonic acid esters, processes for their preparation, and their use |
02/22/2000 | US6027934 Nucleic acid and vectors encoding an immunodominant fragment of a unique protein antigen originally derived from trypanosoma brucei rhodesiense organisms can induce immunoprotection such as against trypanosomes, leishmania |
02/22/2000 | US6027927 Human trk receptors and neurotrophic factor inhibitors |
02/22/2000 | US6027919 BMP-12 and BMP-13 proteins and DNA encoding them |
02/22/2000 | US6027918 Dna molecule encoding a thermostable enzyme from the genus sulfolobus; vectors and transformed host cells; releases trehalose from nonreducing saccharides having trehalose as an end unit and a degree of glucose polymerization of at least 3 |
02/22/2000 | US6027901 CYP7 promoter-binding factors |
02/22/2000 | US6027885 Method for electrochemiluminescent labeling of nucleic acid, use in detection, and compositions therefor |
02/22/2000 | US6027880 Arrays of nucleic acid probes and methods of using the same for detecting cystic fibrosis |
02/22/2000 | US6027877 Use of immobilized mismatch binding protein for detection of mutations and polymorphisms, purification of amplified DNA samples and allele identification |
02/22/2000 | US6027709 Fluorescent cyanine dyes |
02/22/2000 | CA1340906C Fibronectin binding protein as well as its preparation |
02/22/2000 | CA1340903C Process for stabilizing a plasmid present in a bacterial strain and strain thus obtained |
02/17/2000 | WO2000008214A1 Oligonucleotide analogs having modified dimers |
02/17/2000 | WO2000008213A1 Oligomers which inhibit expression of collagen genes |
02/17/2000 | WO2000008196A2 Urate oxidase |
02/17/2000 | WO2000008180A2 HUMAN cDNAs ENCODING POLYPEPTIDES HAVING KINASE FUNCTIONS |
02/17/2000 | WO2000008141A2 Short oligonucleotides for the inhibition of vegf expression |
02/17/2000 | WO2000008140A2 Antisense oligonucleotides for the inhibition of vegf expression |
02/17/2000 | WO2000008139A1 Tumor necrosis factor-gamma |
02/17/2000 | WO2000008044A1 2'-o-aminoethyloxyethyl-modified oligonucleotides |
02/17/2000 | WO2000008042A1 Aminooxy-modified nucleosidic compounds and oligomeric compounds prepared therefrom |
02/17/2000 | WO1999050461A9 Therapeutic and diagnostic applications based on the role of the cxcr-4 gene in tumorigenesis |
02/17/2000 | WO1999047923A9 Assays for screening compounds which interact with cation channel proteins, mutant prokaryotic cation channel proteins, and uses thereof |
02/17/2000 | CA2672025A1 Genes involved in tolerance to environmental stress |
02/17/2000 | CA2339416A1 Short oligonucleotides for the inhibition of vegf expression |
02/17/2000 | CA2339408A1 Aminooxy-modified nucleosidic compounds and oligomeric compounds prepared therefrom |
02/17/2000 | CA2339348A1 Oligomers which inhibit expression of collagen genes |
02/17/2000 | CA2339340A1 Antisense oligonucleotides for the inhibition of vegf expression |
02/17/2000 | CA2339178A1 2'-o-aminoethyloxyethyl-modified oligonucleotides |
02/17/2000 | CA2305308A1 Human cdnas encoding polypeptides having kinase functions |
02/16/2000 | EP0979869A1 Short oligonucleotides for the inhibition of VEGF expression |
02/16/2000 | EP0979868A2 Electrophoretic separation of nucleic acids from proteins at low pH |
02/16/2000 | EP0979309A1 Oligonucleotides for enhanced bioavailability |
02/16/2000 | EP0979293A1 Transcriptional silencing elements and their binding factors |
02/16/2000 | EP0979277A1 Novel human tumour suppressor gene |
02/16/2000 | EP0979273A1 MODIFIED ANTISENSE NUCLEOTIDES COMPLEMENTARY TO A SECTION OF THE HUMAN Ha-Ras GENE |
02/16/2000 | EP0979236A1 Apparatus for synthesis of oligomers, especially peptoids, with reagent recycling |
02/16/2000 | EP0979233A1 Method for solution phase synthesis of oligonucleotides |
02/16/2000 | EP0979102A1 Polyalkylene oxide-modified single chain polypeptides |
02/16/2000 | EP0691948B1 Protecting group for use in oligodeoxyribonucleotide synthesis |
02/16/2000 | CN1244803A Soluble CTLA4 mutant molecules and uses thereof |
02/16/2000 | CN1244583A Preparation and application of native swine vescular disease virus strain and its variant strain |
02/16/2000 | CN1049357C Treatment of human viral infection by ds RNA combined with viral inhibitors |
02/15/2000 | US6025505 Fluorescent labeling probes for immunoassays, dna sequencing, detecting products of polymerase chain reactions |
02/15/2000 | US6025482 Backbone modified oligonucleotide analogs and preparation thereof through reductive coupling |
02/15/2000 | US6025339 Oligo is antisense to the initiation codon, the coding region or the 5' and 3' intronexon junctions of a gene encoding the adenosine a.sub.1 receptor or antisense to an adenosine a.sub.1 receptor mrna; and |
02/15/2000 | US6025335 L-deoxyribofuranosyl nucleoside phosphodiester dimers where the sugar moiety or at least one of the nucleosides has an l-configuration, cancer and viral infections, in mammals. |
02/15/2000 | US6025325 Pegylated obese (ob) protein compositions |
02/15/2000 | US6025198 Antisense modulation of Ship-2 expression |
02/15/2000 | US6025167 RNA ribozyme polymerases, dephosphorylases, restriction endoribonucleases and methods |
02/15/2000 | US6025166 Human trk receptors and neurotrophic factor inhibitors |
02/15/2000 | US6025136 Methods and apparatus for DNA sequencing and DNA identification |
02/15/2000 | US6025130 Nucleotide sequence of gene; for screening of homozygotes, diagnosis, and prenatal screening using oligonucleotide primers |
02/15/2000 | US6024925 Systems and methods for preparing low volume analyte array elements |
02/15/2000 | CA2189941C Fluorescence polarization detection of nucleic acids |
02/15/2000 | CA2015994C Human lactoferrin cdna sequence |
02/15/2000 | CA2006008C Method for making synthetic oligonucleotides which bind specifically to target sites on duplex dna molecules, by forming a colinear triplex, the synthetic oligonucleotides and methods of use |
02/10/2000 | WO2000006779A1 Reversible inhibiting probes |
02/10/2000 | WO2000006772A1 Mutations in and genomic structure of herg - a long qt syndrome gene |
02/10/2000 | WO2000006771A2 Nucleic acid labeling compounds |
02/10/2000 | WO2000006590A1 Rna targeted 2'-modified oligonucleotides that are conformationally preorganized |
02/10/2000 | WO2000006588A1 STEREOISOMERS OF CpG OLIGONUCLEOTIDES AND RELATED METHODS |
02/10/2000 | WO2000006587A1 New cofactors for methyltransferases |
02/10/2000 | WO1999061012A3 Therapeutic dinucleotide and derivatives |
02/10/2000 | CA2339016A1 Nucleic acid labeling compounds |
02/10/2000 | CA2336539A1 Reversible inhibiting probes |
02/10/2000 | CA2333854A1 Stereoisomers of cpg oligonucleotides and related methods |
02/09/2000 | EP0978570A2 Detecting mycobacterium tuberculosis by nucleic acid sequence amplification |
02/09/2000 | EP0978561A1 Antisense oligonucleotides for the inhibition of VEGF expression |
02/09/2000 | EP0977850A1 Edg-1-like receptor |
02/09/2000 | EP0977769A2 A process for the synthesis of modified p-chiral nucleotide analogues |
02/09/2000 | EP0977767A1 Aminooxy-modified oligonucleotides |
02/09/2000 | EP0746332B1 Dna encoding a human neuropeptide y/peptide yy/pancreatic polypeptide receptor (y4) and uses thereof |
02/08/2000 | US6022959 Conjugate binding a texaphyrin and an oligonucleotide; for the hydrolysis of ribonucleic acid |
02/08/2000 | US6022855 Novel variants of the naturally-occurring protease inhibitor, alpha1-antitrypsin and derived peptides comprising a sequence of-arg-xaa-xaa-arg-; viricides; bactericides; blocking of endoproteolytic activation of a bacterial toxin |
02/08/2000 | US6022848 Inhibitor of stem cell proliferation and uses thereof |
02/08/2000 | US6022715 Method for the specific coupling of the cap of the 5' end of an mRNA fragment and preparation of mRNA and complete cDNA |
02/08/2000 | US6022714 Methods for attachment of a polynucleotide to a preselected material |
02/08/2000 | US6022712 Producing heterologous polypeptides in saccharomyces; constructing a vector, introducing vector into saccharomyces, and inducing heterologous polypeptide production |
02/08/2000 | US6022690 Polynucleotides for detecting leishmanias and method of detection of leishmanial protozoan |
02/08/2000 | US6022535 Administering human interleukin-3 variant or mutant proteins (muteins) fused with other colony stimulating factors, cytokines, lyphokines, interleukins, hematopoietic growth factors; treating side effects of cancer radiation therapy |
02/03/2000 | WO2000005358A1 Methods for purifying nucleic acids |
02/03/2000 | WO1999051773A9 Addressable protein arrays |
02/03/2000 | WO1999046400A9 Compositions and methods for enhanced synthesis of nucleic acid molecules |
02/03/2000 | DE19824868C1 Device for storing and processing information comprises immobilized sequence, e.g. DNA, forming reversible secondary structure |
02/03/2000 | CA2338397A1 Methods for purifying nucleic acids |
02/02/2000 | EP0976826A1 Gene encoding recombinant trehalose phosphorylase, vector containing the gene, transformant transformed by the gene, and method for producing recombinant trehalose phosphorylase with the use of the transformant |
02/02/2000 | EP0975741A2 Alpha/beta hydrolase-fold enzymes |
02/02/2000 | EP0975654A1 Composition and method for treatment of cmv infections |