Patents
Patents for C07H 21 - Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids (89,892)
02/2000
02/24/2000CA2333901A1 Low adenosine anti-sense oligonucleotide agent, composition, kit and treatments
02/23/2000EP0980912A1 Alkaline ceramidase (E.C. 3.5.1.23) gene from Pseudomonas aeruginosa
02/23/2000EP0980379A2 Chimeric oligonucleotides and the use thereof
02/23/2000EP0980378A1 Method for detecting the presence of biological matters of bovine origin, and oligonucleotides for its implementation
02/23/2000EP0730663A4 Arrays of nucleic acid probes on biological chips
02/23/2000CN1245503A Oil bodies and associated proteins as affinity matrices
02/23/2000CN1049686C Diagnostics and vaccines for hepatits virus non-A and non-B
02/22/2000US6028189 Solvent for oligonucleotide synthesis and methods of use
02/22/2000US6028188 Synthetic oligomers having chirally pure phosphonate internucleosidyl linkages mixed with non-phosphonate internucleosidyl linkages
02/22/2000US6028186 High affinity nucleic acid ligands of cytokines
02/22/2000US6028183 Pyrimidine derivatives and oligonucleotides containing same
02/22/2000US6028182 Methylphosphonic acid esters, processes for their preparation, and their use
02/22/2000US6027934 Nucleic acid and vectors encoding an immunodominant fragment of a unique protein antigen originally derived from trypanosoma brucei rhodesiense organisms can induce immunoprotection such as against trypanosomes, leishmania
02/22/2000US6027927 Human trk receptors and neurotrophic factor inhibitors
02/22/2000US6027919 BMP-12 and BMP-13 proteins and DNA encoding them
02/22/2000US6027918 Dna molecule encoding a thermostable enzyme from the genus sulfolobus; vectors and transformed host cells; releases trehalose from nonreducing saccharides having trehalose as an end unit and a degree of glucose polymerization of at least 3
02/22/2000US6027901 CYP7 promoter-binding factors
02/22/2000US6027885 Method for electrochemiluminescent labeling of nucleic acid, use in detection, and compositions therefor
02/22/2000US6027880 Arrays of nucleic acid probes and methods of using the same for detecting cystic fibrosis
02/22/2000US6027877 Use of immobilized mismatch binding protein for detection of mutations and polymorphisms, purification of amplified DNA samples and allele identification
02/22/2000US6027709 Fluorescent cyanine dyes
02/22/2000CA1340906C Fibronectin binding protein as well as its preparation
02/22/2000CA1340903C Process for stabilizing a plasmid present in a bacterial strain and strain thus obtained
02/17/2000WO2000008214A1 Oligonucleotide analogs having modified dimers
02/17/2000WO2000008213A1 Oligomers which inhibit expression of collagen genes
02/17/2000WO2000008196A2 Urate oxidase
02/17/2000WO2000008180A2 HUMAN cDNAs ENCODING POLYPEPTIDES HAVING KINASE FUNCTIONS
02/17/2000WO2000008141A2 Short oligonucleotides for the inhibition of vegf expression
02/17/2000WO2000008140A2 Antisense oligonucleotides for the inhibition of vegf expression
02/17/2000WO2000008139A1 Tumor necrosis factor-gamma
02/17/2000WO2000008044A1 2'-o-aminoethyloxyethyl-modified oligonucleotides
02/17/2000WO2000008042A1 Aminooxy-modified nucleosidic compounds and oligomeric compounds prepared therefrom
02/17/2000WO1999050461A9 Therapeutic and diagnostic applications based on the role of the cxcr-4 gene in tumorigenesis
02/17/2000WO1999047923A9 Assays for screening compounds which interact with cation channel proteins, mutant prokaryotic cation channel proteins, and uses thereof
02/17/2000CA2672025A1 Genes involved in tolerance to environmental stress
02/17/2000CA2339416A1 Short oligonucleotides for the inhibition of vegf expression
02/17/2000CA2339408A1 Aminooxy-modified nucleosidic compounds and oligomeric compounds prepared therefrom
02/17/2000CA2339348A1 Oligomers which inhibit expression of collagen genes
02/17/2000CA2339340A1 Antisense oligonucleotides for the inhibition of vegf expression
02/17/2000CA2339178A1 2'-o-aminoethyloxyethyl-modified oligonucleotides
02/17/2000CA2305308A1 Human cdnas encoding polypeptides having kinase functions
02/16/2000EP0979869A1 Short oligonucleotides for the inhibition of VEGF expression
02/16/2000EP0979868A2 Electrophoretic separation of nucleic acids from proteins at low pH
02/16/2000EP0979309A1 Oligonucleotides for enhanced bioavailability
02/16/2000EP0979293A1 Transcriptional silencing elements and their binding factors
02/16/2000EP0979277A1 Novel human tumour suppressor gene
02/16/2000EP0979273A1 MODIFIED ANTISENSE NUCLEOTIDES COMPLEMENTARY TO A SECTION OF THE HUMAN Ha-Ras GENE
02/16/2000EP0979236A1 Apparatus for synthesis of oligomers, especially peptoids, with reagent recycling
02/16/2000EP0979233A1 Method for solution phase synthesis of oligonucleotides
02/16/2000EP0979102A1 Polyalkylene oxide-modified single chain polypeptides
02/16/2000EP0691948B1 Protecting group for use in oligodeoxyribonucleotide synthesis
02/16/2000CN1244803A Soluble CTLA4 mutant molecules and uses thereof
02/16/2000CN1244583A Preparation and application of native swine vescular disease virus strain and its variant strain
02/16/2000CN1049357C Treatment of human viral infection by ds RNA combined with viral inhibitors
02/15/2000US6025505 Fluorescent labeling probes for immunoassays, dna sequencing, detecting products of polymerase chain reactions
02/15/2000US6025482 Backbone modified oligonucleotide analogs and preparation thereof through reductive coupling
02/15/2000US6025339 Oligo is antisense to the initiation codon, the coding region or the 5' and 3' intronexon junctions of a gene encoding the adenosine a.sub.1 receptor or antisense to an adenosine a.sub.1 receptor mrna; and
02/15/2000US6025335 L-deoxyribofuranosyl nucleoside phosphodiester dimers where the sugar moiety or at least one of the nucleosides has an l-configuration, cancer and viral infections, in mammals.
02/15/2000US6025325 Pegylated obese (ob) protein compositions
02/15/2000US6025198 Antisense modulation of Ship-2 expression
02/15/2000US6025167 RNA ribozyme polymerases, dephosphorylases, restriction endoribonucleases and methods
02/15/2000US6025166 Human trk receptors and neurotrophic factor inhibitors
02/15/2000US6025136 Methods and apparatus for DNA sequencing and DNA identification
02/15/2000US6025130 Nucleotide sequence of gene; for screening of homozygotes, diagnosis, and prenatal screening using oligonucleotide primers
02/15/2000US6024925 Systems and methods for preparing low volume analyte array elements
02/15/2000CA2189941C Fluorescence polarization detection of nucleic acids
02/15/2000CA2015994C Human lactoferrin cdna sequence
02/15/2000CA2006008C Method for making synthetic oligonucleotides which bind specifically to target sites on duplex dna molecules, by forming a colinear triplex, the synthetic oligonucleotides and methods of use
02/10/2000WO2000006779A1 Reversible inhibiting probes
02/10/2000WO2000006772A1 Mutations in and genomic structure of herg - a long qt syndrome gene
02/10/2000WO2000006771A2 Nucleic acid labeling compounds
02/10/2000WO2000006590A1 Rna targeted 2'-modified oligonucleotides that are conformationally preorganized
02/10/2000WO2000006588A1 STEREOISOMERS OF CpG OLIGONUCLEOTIDES AND RELATED METHODS
02/10/2000WO2000006587A1 New cofactors for methyltransferases
02/10/2000WO1999061012A3 Therapeutic dinucleotide and derivatives
02/10/2000CA2339016A1 Nucleic acid labeling compounds
02/10/2000CA2336539A1 Reversible inhibiting probes
02/10/2000CA2333854A1 Stereoisomers of cpg oligonucleotides and related methods
02/09/2000EP0978570A2 Detecting mycobacterium tuberculosis by nucleic acid sequence amplification
02/09/2000EP0978561A1 Antisense oligonucleotides for the inhibition of VEGF expression
02/09/2000EP0977850A1 Edg-1-like receptor
02/09/2000EP0977769A2 A process for the synthesis of modified p-chiral nucleotide analogues
02/09/2000EP0977767A1 Aminooxy-modified oligonucleotides
02/09/2000EP0746332B1 Dna encoding a human neuropeptide y/peptide yy/pancreatic polypeptide receptor (y4) and uses thereof
02/08/2000US6022959 Conjugate binding a texaphyrin and an oligonucleotide; for the hydrolysis of ribonucleic acid
02/08/2000US6022855 Novel variants of the naturally-occurring protease inhibitor, alpha1-antitrypsin and derived peptides comprising a sequence of-arg-xaa-xaa-arg-; viricides; bactericides; blocking of endoproteolytic activation of a bacterial toxin
02/08/2000US6022848 Inhibitor of stem cell proliferation and uses thereof
02/08/2000US6022715 Method for the specific coupling of the cap of the 5' end of an mRNA fragment and preparation of mRNA and complete cDNA
02/08/2000US6022714 Methods for attachment of a polynucleotide to a preselected material
02/08/2000US6022712 Producing heterologous polypeptides in saccharomyces; constructing a vector, introducing vector into saccharomyces, and inducing heterologous polypeptide production
02/08/2000US6022690 Polynucleotides for detecting leishmanias and method of detection of leishmanial protozoan
02/08/2000US6022535 Administering human interleukin-3 variant or mutant proteins (muteins) fused with other colony stimulating factors, cytokines, lyphokines, interleukins, hematopoietic growth factors; treating side effects of cancer radiation therapy
02/03/2000WO2000005358A1 Methods for purifying nucleic acids
02/03/2000WO1999051773A9 Addressable protein arrays
02/03/2000WO1999046400A9 Compositions and methods for enhanced synthesis of nucleic acid molecules
02/03/2000DE19824868C1 Device for storing and processing information comprises immobilized sequence, e.g. DNA, forming reversible secondary structure
02/03/2000CA2338397A1 Methods for purifying nucleic acids
02/02/2000EP0976826A1 Gene encoding recombinant trehalose phosphorylase, vector containing the gene, transformant transformed by the gene, and method for producing recombinant trehalose phosphorylase with the use of the transformant
02/02/2000EP0975741A2 Alpha/beta hydrolase-fold enzymes
02/02/2000EP0975654A1 Composition and method for treatment of cmv infections