Patents for C07H 21 - Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids (89,892) |
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12/22/1999 | EP0964932A2 Methods for identifying herbicidal agents that inhibit d1 protease |
12/22/1999 | EP0964930A1 Catalytic rna molecules |
12/21/1999 | US6005096 For oligonucleotides that are modified to enhance the binding affinity and to bear detectable labels; for diagnostic use |
12/21/1999 | US6005094 Mixture of an acid resistant, antisense oligonucleotide and a carrier; for oral administration |
12/21/1999 | US6005093 Conmpounds used as replacements for one or more complementary nucleoside bases in probes; enable photoactive crosslinking of nucleic acid strands in hybridization assays and therapeutic applications |
12/21/1999 | US6005091 Nucleic acids encoding immunoglobulin domains |
12/21/1999 | US6005087 Nuclease resistant oligonucleotides which are useful as therapeutics, diagnostics, and research reagents for various viral diseases |
12/21/1999 | US6004826 Repair-mediated process for amplifying and detecting nucleic acid sequences |
12/21/1999 | US6004804 Non-chimeric mutational vectors |
12/21/1999 | US6004796 Amino acid sequence of enzyme effective in removal of arginine, phenylalanine or methionine from the n-terminal end of peptides in peptide or peptidomimetic synthesis |
12/21/1999 | US6004752 Solid support with attached molecules |
12/21/1999 | US6004747 Nucleic acid molecule for the detection and identification of salmonella serotypes comprising a single stranded dna fragment |
12/21/1999 | US6004513 Automatic device for nucleic acid sequence detection employing amplification probes |
12/21/1999 | CA2197075C Method of gene therapy using dna vectors without selection marker gene |
12/21/1999 | CA2022942C Method of assessing sensitivity of hiv to zidovudine |
12/19/1999 | CA2242316A1 Dna encoding a plasminogen activating protein |
12/16/1999 | WO1999064631A1 Biomarkers and targets for diagnosis, prognosis and management of prostate, breast and bladder cancer |
12/16/1999 | WO1999064629A1 Acrp30r2, a homolog of acrp30 (30 kd adipocyte complement-related protein) |
12/16/1999 | WO1999064623A1 Support for the parallel identification and establishment of transcription profiles of polynucleic acids |
12/16/1999 | WO1999064589A1 Human receptor tyrosine kinase |
12/16/1999 | WO1999064519A1 Energy transfer assay method and reagent |
12/16/1999 | WO1999064437A1 Nucleotide analogues with 3'-pro-fluorescent fluorophores in nucleic acid sequence analysis |
12/16/1999 | WO1999064434A1 Synthetic methods and intermediates for triester oligonucleotides |
12/16/1999 | WO1999064432A2 Multi-fluorescent hairpin energy transfer oligonucleotides |
12/16/1999 | WO1999064431A2 Purines and pyrimidines linked to a quencher |
12/16/1999 | WO1999055718A3 Solution phase biopolymer synthesis |
12/16/1999 | DE19825899A1 Immobilized oligo- or polynucleotide product useful for identifying and quantifying polynucleotides |
12/16/1999 | CA2335026A1 Multi-fluorescent hairpin energy transfer oligonucleotides |
12/16/1999 | CA2334610A1 Purines and pyrimidines linked to a quencher |
12/16/1999 | CA2330478A1 Support for the parallel identification and establishment of transcription profiles of polynucleic acids |
12/15/1999 | EP0963997A1 Novel nucleotide analogues |
12/15/1999 | EP0963443A1 Releasable nonvolatile mass-label molecules |
12/15/1999 | EP0963246A1 Automated chemical synthesis device |
12/15/1999 | EP0963208A1 INHIBITION OF Ii SYNTHESIS |
12/15/1999 | EP0788366B1 Use of 2'-substituted oligonucleotides to down-regulating gene expression |
12/15/1999 | EP0786014B1 Massively parallel sequencing of sorted polynucleotides |
12/15/1999 | EP0750612B1 Acridone-derived bisintercalators as chemotherapeutic agents |
12/15/1999 | EP0743949B1 Process for producing endotoxin-free or endotoxin-poor nucleic acids and/or oligonucleotides for gene therapy |
12/15/1999 | EP0529008B1 Modulation of gene expression through interference with rna secondary structure |
12/14/1999 | US6002071 Transcriptional silencing elements and their binding factors |
12/14/1999 | US6001993 Testing the phoshorous bearing monomers for chemical suitability, reacting selected monomers with solid support or growing chain, mixing all supports together, dividing mixture, repeating coupling steps |
12/14/1999 | US6001991 Antisense oligonucleotide modulation of MDR P-glycoprotein gene expression |
12/14/1999 | US6001990 Antisense inhibition of hepatitis C virus |
12/14/1999 | US6001988 High affinity nucleic acid ligands to lectins |
12/14/1999 | US6001983 Oligonucleotides with non-standard bases and methods for preparing same |
12/14/1999 | US6001982 Synthesis of oligonucleotides |
12/14/1999 | US6001966 Reacting n-terminal protected amino acid with peptide starting material forming a peptide product, partitioning from unreacted material and reagents based on presence of n-terminal blocking/anchoring group |
12/14/1999 | US6001841 Cyclobutyl oligonucleotide surrogates |
12/14/1999 | US6001651 Antisense modulation of LFA-3 |
12/14/1999 | US6001611 Modified nucleic acid amplification primers |
12/14/1999 | US6001598 Two new human DnaJ-like proteins |
12/14/1999 | US6001577 Systematic evolution of ligands by exponential enrichment: photoselection of nucleic acid ligands and solution selex |
12/14/1999 | US6001566 DNA polymerase having 3'-intrinsic editing activity |
12/14/1999 | US6000772 Tubulin promoter regulates gene expression in neurons |
12/14/1999 | CA2186526C Method and product for regulating cell responsiveness to external signals |
12/14/1999 | CA2155024C Genetic modification of neural stem cells |
12/14/1999 | CA1340852C Process for purifying primate gm-csf protein |
12/14/1999 | CA1340847C Adhesin antigens |
12/09/1999 | WO1999063111A2 Method of labelling nucleic acid |
12/09/1999 | WO1999063100A1 Process for obtaining transgenic plants which have an improved capacity for the uptake of nutrients and tolerance to toxic compounds which are present in the soil |
12/09/1999 | WO1999062924A1 D-labeled 5'-ribonucleotide and process for producing the same |
12/09/1999 | WO1999062923A2 Immunostimulatory oligonucleotides with modified bases and methods of use thereof |
12/09/1999 | WO1999062922A1 Activators for oligonucleotide synthesis |
12/09/1999 | WO1999062847A2 Construction and use of catalogued nucleic acid libraries that contain advantageously adjusted representations of defined components |
12/09/1999 | WO1999054340A8 Endotoxin reduction in nucleic acid purification |
12/09/1999 | WO1999027081A3 Alpha/beta hydrolase-fold enzymes |
12/09/1999 | WO1998005673A8 Methods for purifying nucleic acids |
12/09/1999 | CA2330827A1 Construction and use of catalogued nucleic acid libraries that contain advantageously adjusted representations of defined components |
12/09/1999 | CA2330225A1 Immunostimulatory oligonucleotides with modified bases and methods of use thereof |
12/09/1999 | CA2330192A1 Activators for oligonucleotide synthesis |
12/08/1999 | EP0962537A2 Methods and compositions for analyzing nucleic acid molecules utilizing sizing techniques |
12/08/1999 | EP0962463A1 Uncharged morpholino-based polymers having phosphorus-containing chiral intersubunit linkages |
12/08/1999 | EP0961837A1 Three component chimeric antisense oligonucleotides |
12/08/1999 | EP0961831A1 Human endokine alpha |
12/08/1999 | EP0961652A1 Laminated assembly for active bioelectronic devices |
12/08/1999 | EP0850320B1 Methods for detecting binding of ligand pair with enhanced sensitivity |
12/08/1999 | EP0601117B1 SYNTHETIC tRNAs |
12/08/1999 | EP0594837B2 Radiolabelled compound formulations |
12/08/1999 | CN1238012A Stabilized aqueous nucleoside triphosphate solution |
12/08/1999 | CN1237582A Cancer suppressor action of antisense nucteic acid of para-insulin growth factor receptor gene |
12/07/1999 | US5998604 3'- or 5'-polynucleotide cis-diol phosphate diester, reverse phase hplc |
12/07/1999 | US5998603 4'-desmethyl nucleoside analogs, and oligomers thereof |
12/07/1999 | US5998602 RNase L activators and antisense oligonucleotides effective to treat RSV infections |
12/07/1999 | US5998601 VR-2332 viral nucleotide sequence and methods of use |
12/07/1999 | US5998596 Inhibition of protein kinase activity by aptameric action of oligonucleotides |
12/07/1999 | US5998594 Self-assembling, chromogenic receptors for the recognition of medically important substrates and their method of use |
12/07/1999 | US5998203 Enzymatic nucleic acids containing 5'-and/or 3'-cap structures |
12/07/1999 | US5998145 Method to determine predisposition to hypertension |
12/07/1999 | US5998142 Nucleic acid ligand which binds to protein |
12/07/1999 | US5998135 Energy transfer hybridization assay using intercalators and lanthanide metals |
12/07/1999 | US5998133 Use of genetic markers to diagnose familial dysautonomia |
12/07/1999 | US5997870 Isolated peptides which bind to HLA-B44 Molecules |
12/07/1999 | CA1340846E Expression of biologically active platelet derived growth factor analogs in eucaryotic cells |
12/07/1999 | CA1340843C Selective amplification of target polynucleotide sequences |
12/02/1999 | WO1999061653A2 Light-mediated regional analysis of biologic material |
12/02/1999 | WO1999061652A1 Carotenoid ketolase genes and gene products, production of ketocarotenoids and methods of modifying carotenoids using the genes |
12/02/1999 | WO1999061607A2 Antisense oligonucleotides for treating proliferating cells |
12/02/1999 | WO1999061603A1 Rapid and simple process for isolation of circular nucleic acids |
12/02/1999 | WO1999061462A1 Antisense modulation of cellular adhesion molecule expression and treatment of cellular adhesion molecule-associated diseases |
12/02/1999 | WO1999061461A1 Sandwich arrays and methods of making and using the same |