Patents
Patents for C07H 21 - Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids (89,892)
03/1999
03/30/1999US5888751 Method for diagnosis and treating cancers, and methods for identifying pathogenic markers in a sample of normal cells
03/30/1999US5888739 Fluorescence analysis
03/30/1999US5888729 Oligonucleotide probes and methods for detecting Streptococcus pneumoniae
03/30/1999US5888728 Filtration of solution of sample dna and two sets of single stranded binding proteins or complementary oligonucleotide probes with avidin or label attached, forming complex with biotinylated hapten on membrane, thus localizing complex
03/30/1999CA2249058A1 Biologically tolerated low molecular weight polyethylenimines
03/25/1999WO1999014346A2 SENSE mRNA THERAPY
03/25/1999WO1999014341A2 Proteases from gram-positive organisms
03/25/1999WO1999014227A1 Polynucleotide purification method
03/25/1999WO1999014226A2 Bi- and tri-cyclic nucleoside, nucleotide and oligonucleotide analogues
03/25/1999WO1999014224A1 Rapid rna isolation procedure
03/25/1999WO1999013976A1 Apparatuses and methods for isolating nucleic acid
03/25/1999WO1999013886A1 Multiple target hybridizing nucleic acids, their preparation, compositions, formulation, kits and applications
03/25/1999WO1999007383B1 Composition and method for regulating cell proliferation and cell death
03/25/1999WO1999001571A3 Compositions and methods for detecting vancomycin resistant enterococci by cycling probe reactions
03/25/1999WO1998055509A3 Two human dnaj-like proteins
03/25/1999WO1998055508A3 HUMAN PROTEINS HAVING TRANSMEMBRANE DOMAINS AND DNAs ENCODING THESE PROTEINS
03/25/1999WO1998051819A9 Methods for electronic fluorescent perturbation for analysis and electronic perturbation catalysis for synthesis
03/25/1999DE19741738A1 Linker nucleoside(s) containing alkenyloxy or phthalimido-alkyl groups
03/25/1999DE19741715A1 New pentopyranosyl nucleoside compounds
03/25/1999CA2304982A1 Sense mrna therapy
03/25/1999CA2304312A1 Multiple target hybridizing nucleic acids, their preparation, compositions, formulation, kits and applications
03/25/1999CA2303398A1 Rapid rna isolation procedure
03/25/1999CA2303299A1 Bi- and tri-cyclic nucleoside, nucleotide and oligonucleotide analogues
03/24/1999EP0903406A1 Modulation of gene expression through interference with RNA secondary structure
03/24/1999EP0902839A1 Method for inhibiting adenylosuccinate synthetase activity methylthioadenosine phosphorylase deficient cells
03/24/1999EP0902788A1 Nucleoside derivatives, and their use in oligonucleotide synthesis
03/24/1999EP0902780A1 Quaternary cytofectins
03/24/1999EP0810878B1 Rna photocleavage using texaphyrins
03/24/1999CN1212021A Method and compositions for determining sequence of nucleic acid molecules
03/24/1999CN1212020A Method and compositions for analyzing nucleic acid molecules utilizing sizing techniques
03/24/1999CN1212019A Method and compositions for detecting binding of ligand pair using non-fluorescent label
03/24/1999CN1211989A Composition and method for delivery of nucleic acids
03/24/1999CN1211924A Immunomodulatory complex for helicobacter bacteria
03/24/1999CN1211923A Ligands to enhance cellular uptake of biomolecules
03/23/1999US5886193 Coupling to a support carriers
03/23/1999US5886177 Phosphate linked oligomers
03/23/1999US5886165 Mixed backbone antisense oligonucleotides containing 2'-5'-ribonucleotide- and 3'-5'-deoxyribonucleotides segments
03/23/1999US5885970 Antisense oligonucleotides against human protein kinase C
03/23/1999US5885837 Very large scale immobilized polymer synthesis using mechanically directed flow paths
03/23/1999US5885811 Leader sequence inducing a post-translational modification of polypeptides in bacteria gene therefor and subtilin variant of enhanced stability and activity
03/23/1999US5885810 Process for the production of prenyl diphosphate using mutants of geranylgeranyl diphosphate synthase
03/23/1999US5885795 Methods of expressing angiostatic protein
03/23/1999US5885778 Using the dyes in dna analysis, dna sequence determination
03/23/1999CA2140910C An improved method of agrobacterium-mediated transformation of cultured soybean cells
03/23/1999CA1340460C Electrochemiluminescent rhenium moieties and methods for their use
03/23/1999CA1340456C Chimeric rodent/human immunoglobulins specific for tumor-associated antigens
03/19/1999CA2211003A1 Human tumor necrosis factor receptor
03/18/1999WO1999013105A1 Method for the preparation of a probe for nucleic acid hybridization
03/18/1999WO1999013093A1 Expression vector for improved production of polypeptides in yeast
03/18/1999WO1999013090A1 Regulation of protein secretion
03/18/1999WO1999013071A1 Human papilloma virus inhibition by anti-sense oligonucleotides
03/18/1999WO1999012951A1 Uses of nicotinamide adenine dinucleotide and its analogs for treatment of malignant and infectious diseases
03/18/1999WO1999012949A2 AMINO ACID SEQUENCES AND METHOD FOR ISOLATING BACTERIES FROM THE TYPE GENUS $i(PSEUDOMONAS)
03/18/1999WO1999012567A1 Regulation of osteoclast formation by inhibition of osteoblastic stem cell factor
03/18/1999WO1999012557A1 Novel prokaryotic polynucleotides, polypeptides and their uses
03/18/1999WO1999012414A1 Transplacental delivery of oligonucleotides
03/18/1999WO1998049179A3 A process for the synthesis of modified p-chiral nucleotide analogues
03/18/1999CA2303616A1 Transplacental delivery of oligonucleotides
03/18/1999CA2302687A1 Uses of nicotinamide adenine dinucleotide and its analogs for treatment of malignant and infectious diseases
03/18/1999CA2302148A1 Human papilloma virus inhibition by anti-sense oligonucleotides
03/18/1999CA2301979A1 Regulation of osteoclast formation by inhibition of osteoblastic stem cell factor
03/18/1999CA2301909A1 Expression vector for improved production of polypeptides in yeast
03/17/1999EP0902034A2 Very large scale immobilized peptide synthesis
03/17/1999EP0901526A1 Cortistatin: neuropeptides, compositions and methods
03/17/1999EP0901501A1 Nucleoside derivatives with photo-unstable protective groups
03/17/1999EP0901500A1 $i(IN SITU) PREPARATION OF NUCLEOSIDE PHOSPHORAMIDITES AND THEIR USE IN SYNTHESIS OF OLIGONUCLEOTIDES
03/17/1999EP0692026B1 A human t-cell receptor of the g-protein coupled receptor family
03/17/1999EP0648222A4 Methods of single nucleotide primer extension to detect specific alleles and kits therefor.
03/16/1999US5883238 Process for typing HLA-B using specific primers and probes sets
03/16/1999US5883237 Oligonucleotides having Rp and Sp linkages at predetermined locations
03/16/1999US5882927 Oligonucleotide inhibition of protein kinase C
03/16/1999US5882909 Gene codes for sulfolobus with phenylalanine, methionine, valine, tyrosine, arginine and aspartic acid
03/16/1999US5882876 Amino acid sequences in proteins and markers of cancer cells
03/16/1999US5882864 Biomarkers and targets for diagnosis, prognosis and management of prostate disease
03/16/1999CA1340431C Immunologically active peptides capable of inducing immunization against malaria and genes encoding therefor
03/11/1999WO1999011813A2 Oligonucleotide probes bearing quenchable fluorescent labels, and methods of use thereof
03/11/1999WO1999011663A1 HUMAN DEFENSIN DEF-X, GENE AND DNAc, COMPOSITION CONTAINING SAME AND DIAGNOSTIC AND THERAPEUTIC APPLICATIONS
03/11/1999WO1999011283A1 Method for treating a subject suffering from conditions associated with an extracellular zinc sphingomyelinase
03/11/1999DE19739611A1 Nucleinsäure-Sequenzen und Verfahren zum Nachweis von Bakterien der Gattung Pseudomonas Nucleic acid sequences and methods for detecting bacteria of the genus Pseudomonas
03/11/1999CA2302168A1 Method for treating a subject suffering from conditions associated with an extracellular zinc sphingomyelinase
03/10/1999EP0900805A2 Incorporation of selectably cleavable and/or abasic sites into oligonucleotide chains and reagents therefor
03/10/1999EP0900231A1 Flea protease proteins, nucleic acid molecules, and uses thereof
03/10/1999EP0900220A1 3- and 3,8-substituted 1,10-phenanthrolines and their use in electron and energy transfer processes
03/10/1999EP0900025A1 $i(MORAXELLA CATARRHALIS) OUTER MEMBRANE PROTEIN-106 POLYPEPTIDE, GENE SEQUENCE AND USES THEREOF
03/10/1999EP0773951B1 Dinucleoside-5',5'-pyrophosphates
03/09/1999US5880334 DNA encoding phosphoenolpyruvate carboxykinase, recombinant vector and transformed plant containing the same
03/09/1999US5880273 Platelet activating factor acetylhydrolase, and gene thereof
03/09/1999US5880256 Inhibitor is provided in a pharmaceutical composition for treatment of diseases where inhibition of factor viia, factor xia, plasma kallikrein, or plasmin is indicated.
03/09/1999US5879942 Processing enzyme for polypeptide
03/09/1999US5879938 Ribozyme with increased activity by substitution of modified nucleotide into substrate binding arm or catalytic core
03/04/1999WO1999010541A1 Phosphoramidate-phosphodiester oligonucleotide chimera as primers
03/04/1999WO1999010533A1 Rapid detection and identification of micro-organisms
03/04/1999WO1999010527A2 Method for isolating anionic organic substances from aqueous systems using cationic polymer nanoparticles
03/04/1999WO1999010486A2 Mdm2-specific antisense oligonucleotides
03/04/1999WO1999010365A2 5',5'-linked oligomers having anti-thrombin activity
03/04/1999WO1999010001A1 Carcinostatic agents
03/04/1999CA2301816A1 Mdm2-specific antisense oligonucleotides
03/04/1999CA2300885A1 Method for isolating anionic organic substances from aqueous systems using cationic polymer nanoparticles
03/04/1999CA2268371A1 Phosphoramidate-phosphodiester oligonucleotide chimera as primers
03/03/1999EP0898619A1 Chimeric cell-surface receptors that undergo antigen-induced association