| Patents for C07H 21 - Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids (89,892) |
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| 05/09/2000 | US6060057 Cloning and sequencing of allergens of Dermatophagoides (house dust mite) |
| 05/04/2000 | WO2000024927A1 Methods and means for isolating and purifying nucleic acids on surfaces |
| 05/04/2000 | WO2000024885A2 p53 MORPHOLINO-BASED ANTISENSE |
| 05/04/2000 | WO2000024404A1 Thio-modified aptamer synthetic methods and compositions |
| 05/04/2000 | WO1999060146A9 Adeno-associated virus vectors and uses thereof |
| 05/04/2000 | CA2771000A1 Processes and means for the isolation and purification of nucleic acids at surfaces |
| 05/03/2000 | EP0997477A2 MHC complexes and uses thereof |
| 05/03/2000 | EP0996743A2 Compositions and methods for detecting vancomycin resistant enterococci by cycling probe reactions |
| 05/03/2000 | EP0996631A1 Modified nucleic acid analogues |
| 05/03/2000 | EP0996627A1 Method for solution phase synthesis of oligonucleotides and peptides |
| 05/03/2000 | EP0996626A1 Glycine transporter |
| 05/03/2000 | EP0996460A1 TREATMENT OF ACUTE LUNG INJURY AND FIBROSIS WITH ANTAGONISTS OF $g(a)v$g(b)6 |
| 05/03/2000 | EP0669977B1 Transformed endothelial cells |
| 05/03/2000 | EP0624100B1 Dna encoding a human serotonin receptor (5-ht 4b) and uses thereof |
| 05/03/2000 | EP0620863B1 Manipulating nucleic acid sequences |
| 05/03/2000 | EP0383803B1 Oligonucleotide-polyamide conjugates |
| 05/02/2000 | US6057435 Nucleic acid coding for polypeptide which binds to receptor tyrosine kinase containing immunoglobulin-like and epidermal growth factor homology domains expressed in vascular endothelial cells; diagnosis/imaging; angiogenesis inhibition |
| 05/02/2000 | US6057431 Amidite derivatives and oligonucleotide derivatives |
| 05/02/2000 | US6057133 Fusion protein associated with cell growth and regulation; for the activation of bone marrow propagation; for treatment of cancer, asthma and inflammation |
| 05/02/2000 | US6057100 Nucleotide sequences immoblilzed to solid support; for screening and preferential detection of nuclic acids |
| 05/02/2000 | US6057096 Photocleavable agents and conjugates for the detection and isolation of biomolecules |
| 05/02/2000 | CA2207065C Strand displacement amplification using boronated nucleotides |
| 05/02/2000 | CA2104014C Structural gene of pneumococcal protein |
| 05/02/2000 | CA1340978C Purification, cloning and characterization of the gene for interleukin 1 |
| 04/27/2000 | WO2000023577A1 Method for producing chiral carboxylic acids from nitriles with the assistance of a nitrilase or microorganisms which contain a gene for the nitrilase |
| 04/27/2000 | WO2000023458A1 Dna-templated combinatorial library chemistry |
| 04/27/2000 | WO2000023456A1 Functionalized pyrimidine derivatives |
| 04/27/2000 | WO2000023087A1 Polyspecific binding molecules and uses thereof |
| 04/27/2000 | DE19940752A1 Use of an illumination matrix that can be controlled to generate a freely adjustable illumination pattern to produce a microchip |
| 04/27/2000 | CA2346989A1 Dna-templated combinatorial library chemistry |
| 04/27/2000 | CA2315104A1 Functionalized pyrimidine derivatives |
| 04/26/2000 | EP0995800A1 Probes for the diagnosis of infections caused by bacteroides fragilis |
| 04/26/2000 | EP0994951A1 Polynucleotides and their use for detecting resistance to streptogramin a or to streptogramin b and related compounds |
| 04/26/2000 | EP0994728A1 Recombinant antibodies specific for beta-amyloid ends, dna encoding and methods of use thereof |
| 04/26/2000 | CN1251616A Large scale genotyping of diseases and diagnostic test for spinocerebellar ataxia type 6 |
| 04/25/2000 | US6054568 Polymer of nucleobases capable of watson/crick basepairing connected together by linkers and having terminating groups; for nucleic acid analogs which may be used in annealing, ligation, sequencing, cleavage and primer extension reactions |
| 04/25/2000 | US6054439 Antisense olignucleotides having tumorigenicity-inhibiting activity |
| 04/25/2000 | US6054431 Anti-gram-positive bacterial methods and materials |
| 04/25/2000 | US6054321 Forming three-dimensional structure of a fluorescent protein, constructing model of other fluorescent protein using first as template, making mutants by replacing amino acid(s) within 5 angstroms of any atom of chromophore |
| 04/25/2000 | US6054313 For diagnosis of persistant hyperinsulinemic hypoglycemia of infancy; for screening drugs and antidiabetic agents; for gene therapy |
| 04/25/2000 | US6054309 Ceramide glucosyltransferase |
| 04/25/2000 | US6054305 Pyruvate orthophosphate dikinase gene, recombinant DNA, and process for producing pyruvate orthophosphate dikinase |
| 04/25/2000 | US6054279 Detection of nucleic acids by fluorescence quenching |
| 04/25/2000 | US6054273 Inhibitors of alternative alleles of genes as a basis for cancer therapeutic agents |
| 04/25/2000 | US6054132 A purified toxin in diagnostic testing for detecting peptic ulceration and gastric malignancy, and as a vaccine for providing immunologic protection against bacterial infection |
| 04/25/2000 | US6054130 Non-splicing variants of gp350/220 |
| 04/25/2000 | US6054035 DNA sample preparation and electrophoresis analysis apparatus |
| 04/25/2000 | CA2169283C Method of nucleic acid sequence selection |
| 04/25/2000 | CA2015671C Phosphonomethoxytetrahydrofuranyl-purine/pyrimidine derivatives |
| 04/20/2000 | WO2000022172A1 Nucleic acid arrays |
| 04/20/2000 | WO2000022169A1 DETECTION USING Snz AND Sno GENES AND PROTEINS |
| 04/20/2000 | WO2000021974A1 Nucleotide compounds including a rigid linker |
| 04/20/2000 | WO2000021967A1 Functionalized silicon compounds, their synthesis and use |
| 04/20/2000 | WO1999067619A3 Compounds and methods for detecting biomolecules |
| 04/20/2000 | WO1999061653A3 Light-mediated regional analysis of biologic material |
| 04/20/2000 | DE19848129A1 New nucleic acid sequence encoding Alcaligenes faecalis nitrilase polypeptide useful for converting racemic nitriles to chiral carboxylic acids |
| 04/20/2000 | DE19846077A1 Identifying trypanosome-binding nucleic acids and related peptides, useful for treatment and diagnosis of trypanosomal infections comprises treating a nucleic acid with trypanosomes |
| 04/19/2000 | EP0785941B1 Porphyrin labeling of polynucleotides |
| 04/19/2000 | EP0586520B1 Backbone modified oligonucleotide analogs |
| 04/19/2000 | EP0222835B2 Oral vaccines |
| 04/18/2000 | US6051760 Synthetic DNA sequence having enhanced insecticidal activity in maize |
| 04/18/2000 | US6051719 Dibenzorhodamine dyes |
| 04/18/2000 | US6051699 Process for the synthesis of oligomeric compounds |
| 04/18/2000 | US6051698 Vascular endothelial growth factor (VEGF) nucleic acid ligand complexes |
| 04/18/2000 | US6051696 Process for typing of HCV isolates |
| 04/18/2000 | US6051407 A dna encoding a protein; regulating the production of cellulose in prokaryotic and eukaryotic cells |
| 04/18/2000 | US6051406 Keratan sulfate 6-sulfotransferase and DNA coding for the same |
| 04/18/2000 | US6051380 Hybridizing dna in an electrophoresis system using a low conductivity, zwitterionic buffer; transporting dna toward a microlocation where ph of buffer is below the isoelectric point, enhancing hybridization of dna to probe |
| 04/18/2000 | US6051222 Cancer diagnosis; genetic engineering |
| 04/18/2000 | US6051221 BRK protein tyrosine kinase and encoding nucleic acid |
| 04/18/2000 | US6051217 Administering to patient with hematopoietic or immunodeficiency |
| 04/16/2000 | CA2284857A1 G protein coupled receptor a4 |
| 04/13/2000 | WO2000020645A1 ANTISENSE OLIGONUCLEOTIDE MODULATION OF TUMOR NECROSIS FACTOR-α (TNF-α) EXPRESSION |
| 04/13/2000 | WO2000020643A1 Reverse displacement assay for detection of nucleic acid sequences |
| 04/13/2000 | WO2000020639A1 Enzymatic synthesis of oligonucleotide tags |
| 04/13/2000 | WO2000020635A1 ANTISENSE MODULATION OF INTEGRIN α4 EXPRESSION |
| 04/13/2000 | WO2000020555A2 Transformation system in the field of filamentous fungal hosts: in chrysosporium |
| 04/13/2000 | WO2000020433A1 Cytotoxic agents for the selective killing of lymphoma and leukemia cells and methods of use thereof |
| 04/13/2000 | WO2000020432A1 Antisense modulation of bcl-x expression |
| 04/13/2000 | WO2000020431A1 Improved process for oligonucleotide synthesis |
| 04/13/2000 | WO2000020430A1 Crystal of diuridine tetraphosphate or salt thereof and method for preparing the same, and method for producing said compound |
| 04/13/2000 | WO2000020031A1 Methods for identification, diagnosis, and treatment of breast cancer |
| 04/13/2000 | DE19844988A1 Parallele Festphasensynthese Parallel solid phase synthesis |
| 04/13/2000 | CA2346048A1 Methods for identification, diagnosis, and treatment of breast cancer |
| 04/13/2000 | CA2345209A1 Antisense modulation of integrin .alpha.4 expression |
| 04/13/2000 | CA2344616A1 Antisense oligonucleotide modulation of tumor necrosis factor-.alpha. (tnf-.alpha.) expression |
| 04/12/2000 | EP0992584A2 Purified mammalian FLT3 ligands and agonists and antagonists thereof |
| 04/12/2000 | EP0992511A1 Methods and compositions for determining the sequence of nucleic acid molecules |
| 04/12/2000 | EP0992506A2 Process for the sulfurisation of phosphorus-containing compounds |
| 04/12/2000 | EP0868535B1 Methods and compositions for determining the sequence of nucleic acid molecules |
| 04/12/2000 | EP0804414A4 Complementary dna and toxins |
| 04/12/2000 | CN1250369A Method of treating dry eye disease with purinergic receptor agonists |
| 04/11/2000 | US6048982 Oxazole, thiazole or imidazole cyanine dyes for labels |
| 04/11/2000 | US6048974 Nucleotide sequences that serve as clamps for preferentially binding to target polynucleotides forming stable circular structures |
| 04/11/2000 | US6048711 Human G-protein coupled receptor polynucleotides |
| 04/11/2000 | US6048699 Designing biocompatible layout test positions; providing a solution containing probes, using acoustic waves to concentrate the probes at a node intersection and binding the probes on a substrate to form test position |
| 04/11/2000 | US6048698 Producing products by bond formation of a reactant bound to nucleic acid and a free reactant, then contacting product library with target to partition products by ability to perform preselected function |
| 04/11/2000 | US6048695 Nucleic acid modified by addition of epoxide-alkoxysilane compound for immobilization to unmodified or underivatized glass surface; for hybridization microarrays for genome-wide genetic mapping and gene expression studies |
| 04/11/2000 | US6048690 Methods for electronic fluorescent perturbation for analysis and electronic perturbation catalysis for synthesis |
| 04/11/2000 | US6048687 Detecting nucleotide sequence; obtaining sample, mixing sample with reagent, incubating sample with reaction mixture to amplify nucleotide sequence, obtaining samples, adding probe, incubating with second mixture and detecting complex |