Patents
Patents for C07D 453 - Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids (5,704)
07/1993
07/22/1993WO1993014090A1 Heterocyclic compounds and their preparation and use
07/22/1993WO1993014089A1 Heterocyclic compounds and their preparation and use
07/22/1993CA2127251A1 Heterocyclic compounds and their preparation and use
07/21/1993EP0551963A2 Use of heterocyclic derivatives for the manufacture of medicaments
07/20/1993US5229403 Enzyme inhibitors, antiinflammatory
07/20/1993CA1320448C Method of enhancing memory or correcting memory deficiency with arylamido (and arylthioamido)-azabicycloalkanes
07/14/1993EP0550587A1 Stereoselective preparation of acid sensitive amides and intermediates useful in said preparation
07/13/1993US5227543 Facilitation of turnover in the ADH by additives which catalyze the hydrolysis of the OS(VI) glycolate esters
07/13/1993US5227394 Muscarinic cholinergic agonists, cognition activators, analgesics
07/13/1993US5227386 Indole derivatives
07/08/1993WO1993013096A1 Quinuclidine derivatives as squalene synthase inhibitors
07/08/1993WO1993013083A1 Oxadiazole derivatives having acetylcholinesterase-inhibitory and muscarinic agonist activity
07/08/1993CA2126976A1 Oxadiazole derivatives having acetylcholinesterase-inhibitory and muscarinic agonist activity
06/1993
06/29/1993US5223511 Benzimidazoline-2-oxo-1-carboxylic acid compounds useful as 5-HT receptor antagonists
06/24/1993CA2085913A1 Heterocyclic derivatives
06/22/1993US5221593 Silver halide photographic materials containing novel nucleating agent
06/16/1993EP0546181A1 Indole derivatives and their use as serotonin antagonists
06/15/1993US5219849 Substituted pyrazines, pyrimidines and pyridazines for use in the treatment of glaucoma
06/09/1993EP0544779A1 Heterocyclic compounds and their preparation and use
06/08/1993US5217975 Azabicyclic compounds for treating dementia
06/02/1993EP0543969A1 Heterocyclic chiral ligands and method for catalytic asymmetric dihydroxylation of olefins
06/01/1993US5216163 Process for preparing azabicyclo[2.2.2]octan-3-imines
06/01/1993US5215974 Antisecretory agents for gastrointestinal disorders; water solubility, chemical stability
06/01/1993US5215918 Acid anhydride esterification; preferential enzymatic hydrolysis with a subtilisin protease
06/01/1993CA1318595C 2-alkoxy-n-(1-azabicyclo[2.2.2]oct-3-yl) benzamides and thiobenzamides
05/1993
05/18/1993US5212185 Piperidinyl-terminated alkylamino ethynyl alanine amino diol compounds for treatment of hypertension
05/13/1993WO1993009116A1 Quinuclidine compound and medicinal use thereof
05/13/1993WO1993009115A1 Biphenylylquinuclidines, useful as squalene synthetase inhibitors
05/12/1993EP0541407A1 Nitrogen containing bicyclic derivatives, method for their preparation and pharmaceutical compositions containing them
05/12/1993EP0540604A1 Substituted bicyclic bis-aryl compounds exhibiting selective leukotriene b 4? antagonist activity, their preparation and use in pharmaceutical compositions
05/12/1993CN1071916A 2,3-phthalazine containing ether or sulfide group at 1-position and process for preparing same
05/06/1993DE4234933A1 New phthalazine derivs.
05/05/1993EP0539805A1 Phthalazines substituted on position 1 by an ether or a thioether group and process for their preparation
05/05/1993CN1071667A Phenothiazine quaternary ammonium derivative and process for preparing their composition
05/04/1993US5208036 Complexing a liposomal composition with a quaternary ammonium diether
05/01/1993CA2081819A1 Phthalazines containing an ether or thioether group in the 1-position and a process for their preparation
05/01/1993CA2081674A1 Heterocyclic compounds
04/1993
04/29/1993WO1993008192A1 Azabicyclo arylacetylene and arylenyne oximes as cholinergic agents and methods of treatment
04/29/1993WO1993008186A1 Pyridine-3-carboxylic acid esters or amides useful as 5-ht3 antagonists
04/29/1993WO1993007871A1 Methods for the treatment of hyperlipidemia using azaspiranes
04/27/1993US5206246 Anxiolytic-R-n(1-azabicyclo[2.2.2]oct-3-yl) benzamides and thiobenzamides
04/27/1993US5206235 Animal growth regulators; stimulants
04/21/1993CN1071168A Fused tricycle nitrogen containing heterocycles
04/15/1993WO1993007142A1 New ligands for asymmetric dihydroxylation: multiple cinchona alkaloid units attached to a central heterocyclic core
04/14/1993EP0536817A1 Azabicyclic compounds as tachykinin antagonists
04/14/1993CN1070911A Therapeutic compounds
04/13/1993US5202333 Tricyclic 5-HT3 receptor antagonists
04/13/1993US5202318 Tricyclic compounds acting at serotonin receptor subtypes
04/06/1993US5200419 Substituted tetrazoles and derivatives thereof acting at muscarinic receptors
04/01/1993WO1993006099A1 Fused tricyclic nitrogen containing heterocycles as substance p receptor antagonists
04/01/1993WO1993006098A1 Quinuclidine esters process and intermediate for their preparation and pharmaceutical compositions containing them
04/01/1993WO1993006092A1 Piperazinyl (sulfonyl)amide derivatives of camphor as oxytocin antagonists
03/1993
03/31/1993CN1070399A Substituted amide derivatives of piperizinylcamphorsulfonyl oxytocin antagonists
03/30/1993US5198435 Antiinflammatory, antiallergen
03/28/1993CA2079185A1 Dicyclic nitrogens derivatives, preparation process thereof and pharmaceutical compositions containing them
03/24/1993EP0533516A2 Amides of 1-(alkoxybenzyl)piperazines, processes for their preparation and pharmaceutical compositions containing them
03/24/1993EP0533280A1 Novel medical use for tachykinin antagonists
03/24/1993EP0533242A2 Substituted derivatives of piperazinylcamphorsulfonyl oxytocin antagonists
03/24/1993EP0533241A2 Substituted alkyl derivatives of piperazinylcamphorsulfonyl oxytocin antagonists
03/24/1993EP0533240A2 Substituted amine derivatives of piperazinylcamphorsulfonyl oxytocin antagonists
03/24/1993EP0533048A1 Process for the preparation of lactams
03/17/1993EP0532097A1 Piperazinyl(sulfon)amide derivatives of camphor as oxytocin antagonists
03/17/1993CN1069971A Novel sulfonamide fibrinogen receptor antagonists
03/17/1993CN1020102C Preparation for bicyclic carboxylic ether and bicyclic carboxylic amide
03/17/1993CA2078264A1 Substituted derivatives of piperizinylcamphorsulfonyl oxytocin antagonists
03/17/1993CA2078263A1 Substituted alkyl derivatives of piperizinylcamphorsulfonyl oxytocin antagonists
03/17/1993CA2078025A1 Substituted amine derivatives of piperizinylcamphorsulfonyl oxytocin antagonists
03/16/1993US5194605 Cyclic renin inhibitors containing 2-substituted (3S,4S)-4-amino-5-cyclohexyl-3-hydroxy pentanoic acid, 2-substituted (3S,4S)-5-cyclohexyl-3,4-di-hydroxy pentanoic acid or 2-substituted (4S,5S)-5-amino-6-cyclohexyl-4-hydroxyhexanoic acid or its analogs
03/14/1993CA2077922A1 Substituted amide derivatives of piperizinylcamphorsulfonyl oxytocin antagonists
03/10/1993EP0530353A1 New imidazopyridines as serotonergic 5-ht 3? antagonists
03/09/1993US5192770 Serotonergic alpha-oxoacetamides
03/03/1993EP0529462A1 Benzodioxan derivatives
02/1993
02/23/1993US5189061 Fungicide
02/23/1993CA2076573A1 Benzodioxane derivatives
02/21/1993CA2076443A1 1-(alcoxybenzyl)piperazins amidic compounds, process for their preparation and pharmaceutical compositions containing same
02/18/1993WO1993003029A1 (-) and (+) 10-(1-azabicyclo[2.2.2.]oct-3-yl-methyl)-10 h-phenothiazine quaternary ammonium derivatives, pharmaceutical compositions containing them and process for their preparation
02/18/1993CA2114844A1 (-) and (+) 10-(1-azabicyclo[2.2.2.]oct-3-yl-methyl)-10 h-phenothiazine quaternary ammonium derivatives, pharmaceutical compositions containing them and process for their preparation
02/16/1993US5187164 Psychological disorders, antiemetics
02/10/1993EP0526582A1 Heterocyclic chiral ligands and method for catalytic asymmetric dihydroxylation of olefins
02/10/1993EP0526545A1 Isoquinoline amides and esters as 5 ht3 receptor antagonists
02/09/1993US5185333 Benzazine compounds and pharmaceutical uses thereof
02/03/1993EP0525879A1 Pyrazole derivatives
02/03/1993CN1068571A Substituted 3-aminoquinuclidines
02/02/1993US5183893 Alzheimer's disease and learning enhancement
02/02/1993US5183822 Substituted 3,4-annelated benzimidazol-2(1h)-ones
01/1993
01/27/1993CA2074601A1 Pyrazole derivatives
01/26/1993US5182283 Alzheimer's disease
01/19/1993US5180823 Intramolecular Cyclization
01/13/1993EP0523013A2 Use of benzimidazoline-2-oxo-1-carboxylic acid derivatives in the treatment of organic mental diseases
01/07/1993WO1993000331A1 Fluoroalkoxybenzylamino derivatives of nitrogen containing heterocycles
01/06/1993CN1067655A Fluoroalkoxybenzylamino derivatives of nitrogen containing heterocycles
01/06/1993CA2072676A1 Azabicyclic compounds, pharmaceutical compositions containing them and their use in therapy
01/05/1993US5177084 1-Azabicycles, Treating Mental Disorders
01/05/1993CA2072911A1 Use of benzimidazoline-2-oxo-1-carboxylic acid derivatives
12/1992
12/30/1992EP0520555A1 Azabicyclic compounds, pharmaceutical compositions containing them and their use in therapy
12/30/1992CN1067428A 奎宁环衍生物 Quinuclidine derivatives
12/25/1992CA2071800A1 Azabicyclic compounds, pharmaceutical compositions containing them and their use in therapy
12/23/1992WO1992022294A1 Immunomodulatory azaspiranes
12/23/1992CA2110577A1 Immunomodulatory azaspiranes
12/16/1992EP0518676A2 Cyclic renin inhibitors
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