Patents
Patents for C07D 453 - Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids (5,704)
08/1998
08/06/1998WO1998033788A1 Matrix metalloproteinase inhibitors
08/05/1998CN1189829A Piperazino derivatives as neurokinin antagonists
08/04/1998CA2149242C Quinuclidine derivative for treatment of inflammatory and gastrointestinal disorders
07/1998
07/30/1998WO1998032758A1 Single pot process for producing (z)-azabicyclo oxime ethers
07/30/1998CA2270884A1 Single pot process for producing (z)-azabicyclo oxime ethers
07/29/1998EP0854720A1 Nk-1 receptor antagonists for prevention of neurogenic inflammation in gene therapy
07/23/1998WO1998031661A1 Benzamidine derivatives
07/23/1998CA2278180A1 Benzamidine derivatives
07/22/1998EP0853621A1 Novel substituted azacyclic or azabicyclic compounds
07/14/1998US5780494 Piperidinyl-terminated alkylamino ethynl alanine amino diol compounds for treatment of hypertension
07/14/1998US5780466 Substituted heterocyclic compounds method of preparing them and pharmaceutical compositions in which they are present
07/14/1998CA2158130C Process and intermediates for preparing azabicyclo(2.2.2)octan-3-imines
07/08/1998EP0851759A1 Compounds and methods
07/07/1998US5777122 Alkaloids treated with oxidation with air in ether or tetrahydrofuran
07/01/1998EP0850236A1 Piperazino derivatives as neurokinin antagonists
06/1998
06/30/1998US5773619 Process for the preparation of azabicycloc derivatives
06/30/1998US5773575 Reacting a carboxylic acid and amine with coupling agent
06/30/1998US5773450 Fluoroalkoxybenzylamino derivatives of nitrogen containing heterocycles
06/30/1998US5773444 Quinazolines as inhibitors of endothelin converting enzyme
06/23/1998US5770608 Heterocyclic derivatives
06/17/1998EP0847992A1 Benzamide derivatives, useful as cell differentiation inducers
06/17/1998EP0689549B1 New urea derivates, their preparation and their use
06/17/1998CN1038748C Method for prepn. of sulfonamide fibrinogen receptor antagonists
06/10/1998EP0603229B1 Quinuclidine esters process and intermediates for their preparation and pharmaceutical compositions containing them
06/10/1998CN1184469A 1 -phenylpyrazole-3 -carboxamides acting on neurotensin receptors
06/09/1998US5763457 Method for treating anxiety
06/03/1998CN1183781A Novel heterocyclic compounds
05/1998
05/28/1998WO1998022466A1 PROCESS FOR PREPARING MeO-Peg-PROTECTED DIHYDROQUININE OR DIHYDROQUINIDINE DERIVATIVES, NEW DIHYDROQUININE OR DIHYDROQUINIDINE DERIVATIVES AND THEIR USE
05/28/1998DE19750007A1 New poly:alkylene glycol-modified quinine or quinidine derivatives
05/26/1998CA2052073C Sulfonamide fibrinogen receptor antagonists
05/20/1998EP0674636B1 Quinuclidine derivatives as squalene synthase inhibitors
05/20/1998EP0608336B1 Azabicyclo arylacetylene and arylenyne oximes as cholinergic agents and methods of treatment
05/20/1998CN1182082A Preparation of pyrimidine derivatives
05/13/1998EP0841326A1 Process for the preparation of pyrimidine derivatives
05/13/1998EP0840735A1 Resolution of 1-azabicyclo 2.2.2]octan-3-amine, 2-(diphenylmethyl)-n- 2-methoxy-5-(1-methylethyl)phenyl]methyl]
05/13/1998EP0840732A1 Substituted benzolactam compounds as substance p antagonists
05/12/1998US5750538 1,2,5-thiadiazol-4-yl-1-azabicyclic derivatives
05/12/1998CA2030718C Tricyclic compounds
05/07/1998WO1998018788A1 Piperazino derivatives as neurokinin antagonists
05/07/1998WO1998018326A1 Compounds, compositions and methods for treating antibiotic-resistant infections
05/07/1998CA2270123A1 Compounds, compositions and methods for treating antibiotic-resistant infections
05/05/1998US5747522 Anticoagulants; antiinflammatory agents; antitumor agents
04/1998
04/28/1998US5744607 Basic derivatives of glutamic acid and aspartic acid as gastrin or cholecystokinin antagonists
04/28/1998US5744606 Process for the preparation of optically active 3-quinuclidinol
04/28/1998US5744493 3-amidopyrazole derivatives and pharmaceutical compositions containing them
04/28/1998US5744491 3-amidopyrazole derivatives, process for preparing these and pharmaceutical compositions containing them
04/28/1998US5744480 Antiinflammatory agents, nervous system disorders
04/22/1998EP0836604A1 Novel substituted azabicyclic compounds
04/21/1998US5741819 Arylsulfonylaminobenzene derivatives and the use thereof as factor Xa inhibitors
04/21/1998US5741797 Heteroatom substituted alkyl benzylaminoquinuclidines
04/21/1998US5741715 Quinidine immunoassay and reagents
04/16/1998WO1998015551A1 Quinuclidine derivatives as antagonists of muscarinic receptors
04/07/1998CA2146259C Substituted benzylaminoquinuclidines
04/07/1998CA2084193C 3-amino-2-aryl quinuclidines
04/07/1998CA2003441C Quinuclidine therapeutic agents
04/01/1998EP0831800A1 ARYLSULFONYLAMINOBENZENE DERIVATIVES AND THE USE THEREOF AS FACTOR Xa INHIBITORS
03/1998
03/31/1998CA2116356C Antimuscarinic bronchodilators
03/25/1998CN1177353A Novel quinuclidine derivatives having tricyclic fused hereto ring
03/24/1998US5731323 Quinuclidine derivatives as squalene synthase inhibitors
03/19/1998WO1998010761A1 Carbapenem antibacterial compounds, compositions containing such compounds and methods of treatment
03/19/1998CA2264605A1 Carbapenem antibacterial compounds, compositions containing such compounds and methods of treatment
03/18/1998EP0829480A2 Tetrazolyl-substituted quinuclidines as substance P antagonists
03/11/1998EP0636125B1 Basic derivatives of glutamic acid and aspartic acid as gastrin or cholecystokinin antagonists
03/10/1998US5726313 Substituted arylaliphatic compounds, method of preparing them and pharmaceutical compositions in which they are present
03/10/1998US5726193 Method for treating anxiety
03/05/1998WO1998008845A1 Herbicidal s-substituted 1,2,4,6-thiatriazines
03/05/1998WO1998008826A1 Piperazino derivatives as neurokinin antagonists
03/03/1998US5723483 Substituted 1-phenyl-3-pyrazolecarboxamides active on neurotensin receptors, their preparation and pharmaceutical compositions containing them
03/03/1998US5723468 6-membered ring fused imidazoles as muscarinic agents
03/03/1998US5723103 Altered 5-ht-3 or neurotransmitter receptor function
02/1998
02/26/1998WO1998007722A1 Quaternary ammonium compounds as tachykinin antagonist
02/26/1998WO1998007420A1 Neuropeptide-y ligands
02/26/1998CA2268051A1 Neuropeptide-y ligands
02/25/1998CN1174504A Piperidines, pyrrolidines and hexahydro -1H -azepines promote release of growth hormone
02/25/1998CN1037513C Prep. of Pyrimidines and their pharmaceutical acceptable salts
02/24/1998US5721255 Useful for preventing pain, anxiety, migrane, schizophrenia, asthma, rheumatoid arthritis, fibrositis, or ulcerative colitis in mammal
02/24/1998US5721251 Piperidine, pyrrolidine and hexahydro-1H-azepines promote release of growth hormone
02/18/1998EP0823906A1 Piperazino derivatives as neurokinin antagonists
02/18/1998CN1173867A Indolyl neuropeptide Y receptor antagonists
02/17/1998US5719156 Piperazino derivatives as neurokinin antagonists
02/17/1998US5719150 Alzheimer's disease
02/12/1998WO1998005659A1 Azabicyclic carbamoyloxy mutilin derivatives for antibacterial use
02/12/1998WO1998005644A1 New compounds having a selective antitumour, antiviral, antiparasite and antifungic activity, which block biosynthesis of phosphorilcholine by selective inhibition of intracellular choline kinase or its use as second messenger in cellular proliferation
02/12/1998CA2262460A1 Azabicyclic carbamoyloxy mutilin derivatives for antibacterial use
02/11/1998CN1173132A Dihydropyrimidines and uses thereof
02/10/1998US5716965 Substituted 3-aminoquinuclidines
02/05/1998WO1998004517A1 Arylcycloalkane carboxylic esters, their use, pharmaceutical compositions and preparation
02/05/1998WO1998004258A1 Formulation for the treatment and/or prophylaxis of dementia
02/05/1998CA2261692A1 Arylcycloalkane carboxylic esters, their use, pharmaceutical compositions and preparation
02/05/1998CA2261233A1 Formulation for the treatment and/or prophylaxis of dementia
02/04/1998EP0821671A1 Arylsulfonyl hydroxamic acid derivatives as mmp and tnf inhibitors
02/04/1998CN1172483A Substituted heterocyclic compounds, preparation method thereof and pharmaceutical compositions containing same
02/04/1998CN1037269C Method for preparing 3 -quinuclidinyl ester
02/03/1998US5714496 Quinuclidine derivatives as squalene synthase inhibitors
02/03/1998CA2098989C Process and intermediates for preparing azabicyclo(2.2.2)octan-3-imines
01/1998
01/28/1998EP0820451A1 Novel heterocyclic compounds
01/28/1998EP0820444A1 1-phenylpyrazole-3-carboxamides acting on neurotensin receptors
01/27/1998US5712288 Quaternary basic amides, method of preparing them and pharmaceutical compositions in which they are present
01/27/1998US5712287 Method of treating urinary bladder dysfunctions
01/27/1998US5712284 Azalicyclooctane derivatives as anti-arrhythmic agents
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