Patents
Patents for C07D 453 - Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids (5,704)
08/1990
08/16/1990EP0382687A2 Benzofused-N-containing heterocycle derivatives
08/07/1990US4946787 Double coated liposome complex made up of polyanion and a lipid
08/06/1990CA2009300A1 Benzofused-n-containing heterocycle derivatives
08/01/1990EP0379806A2 Pyrimidines and their pharmaceutical acceptable salts, and their use as medicines
07/1990
07/31/1990US4945098 Novel propane-1,3-diol derivatives and use
07/18/1990EP0378111A1 Isoxazole derivatives having anti-serotonin activity, their preparation process and compositions containing them
07/17/1990US4942160 Analgesics, antiinflammatory agents
07/10/1990US4940795 Heterocyclic spiro compounds and methods for preparing the same
07/10/1990US4940705 Viricides
07/10/1990US4940703 Spirocyclic compounds incorporating five-membered rings with two heteroatoms for treating psychotic disorders, etc.
06/1990
06/29/1990CA2006944A1 Pyrimidines and their pharmaceutical acceptable salts, and their use as medicines.
06/26/1990US4937247 Emetic agents, analgesics
06/26/1990US4937239 Azabicycloalkane oxime & azabicycloalkene oxime muscarinic agents
06/26/1990US4937236 Anxiolytic N-substituted benzamides
06/20/1990CN1043130A Quinuclidine therapeutic agents
06/19/1990US4935511 Benzoxazine and benzoxazepine carboxamide 5-HT3 antagonists
06/14/1990WO1990006309A1 Heteroazabenzobicyclic carboxamide 5-ht3, antagonists
06/14/1990WO1990006113A1 Substituted saturated and unsaturated indole quinoline and benzazepine carboxamides and their use as pharmacological agents
06/12/1990US4933445 Antiemetics, gastrointestinal disorders
05/1990
05/31/1990WO1990005729A1 Quinuclidine therapeutic agents
05/31/1990WO1990005525A1 Quinuclidine derivatives as substance p antagonists
05/30/1990EP0370415A1 Quinuclidines, their pharmaceutical use and process for their preparation
05/29/1990US4929625 Ethers
05/16/1990EP0305297B1 Derivatives of aza-z-bicyclooctane-caboxylicacid-3, processes for their preparation and pharmaceutical compositions containing them
05/15/1990US4925942 Preparation of quinuclidine-3-methanol
05/08/1990US4924010 Gastrointestinal disorders
05/02/1990EP0366561A2 1-Azabicycloalkane derivatives, process for their preparation and their use as medicines
05/02/1990EP0366304A2 Heterocyclic derivatives, process for their preparation and pharmaceutical compositions containing them
05/01/1990US4921982 5-halo-2,3-dihydro-2,2-dimethylbenzofuran-7-carboxylic acids useful as intermediates for 5-HT3 antagonists
05/01/1990US4921860 Quinuclidyl- and tropanyl-pyridyl ethers as 5-HT3 receptor antagonists
04/1990
04/28/1990CA2001686A1 Novel derivatives of 1-azabicycloalkanes, process for their preparation and uses as drugs
04/24/1990US4920227 Emetic agents
04/24/1990US4920219 Substituted saturated and unsaturated indole quinoline and benzazepine carboxamides and their use as pharmacological agents
04/24/1990US4920127 Substituted indoles and their use as 5-HT3 receptor antagonists
04/18/1990EP0363466A1 Novel compounds
04/17/1990CA1267898A2 Substituted benzoic acid alkylene bridged piperidyl amides
04/13/1990CA2000041A1 Compounds
04/11/1990EP0363085A2 Novel compounds
04/11/1990EP0362299A1 Bicyclic compounds, their use as pharmaceuticals, their preparation, and intermediates useful in their preparation
04/04/1990EP0361629A2 Heterocyclic compounds
04/03/1990CA2000042A1 Compounds
03/1990
03/28/1990EP0360642A2 Aza-2-bicyclooctane (2,2,2) carboxylic-3-acid derivatives for the treatment of vascular disorders
03/20/1990US4910207 Method of treating psychosis with N-quinuclidinyl-benzamides
03/13/1990US4908370 Antianxiety agents
03/08/1990WO1990002123A1 Amino-substituted bridged azabicyclic quinolone carboxylic acids and esters
02/1990
02/28/1990EP0356193A2 Amino-substituted bridged azabicyclic quinolone carboxylic acids and esters
02/28/1990EP0356152A1 Quaternary ammonium salts
02/20/1990US4902817 Process for the synthesis of alpha n alkylated amino acids and esters thereof, application to the synthesis of carboxyalkyl dipeptides
02/20/1990US4902693 Anti-allergic esters, acetal ethers, thioethers and nitrogen substituted derivatives of bicyclic compounds
02/14/1990EP0354301A2 Process for the preparation of quinuclidine-3-methanol
02/13/1990CA1265802A1 3-amino quinuclidine derivatives, the process for preparing same and the application thereof in therapeutics
02/07/1990EP0353372A1 Antischizophrenic-S-N-(1-azabicyclo[2.2.2.]oct-3-yl) benzamides and thiobenzamides
02/07/1990EP0353371A1 Memory enhancing-R-N-(1-azabicyclo[2.2.2] oct-3-yl) benzamides and thiobenzamides
01/1990
01/31/1990EP0353189A1 Copper and nickel dihalogenide complexes, process for their preparation and their use
01/30/1990US4897487 Process for preparing intermediates for pharmaceutically useful bicyclic compounds
01/30/1990US4897355 Lipisome-polyanion complex
01/10/1990EP0350130A2 New substituted 1,7-annelated 1H-indazoles
01/09/1990US4892872 Benzoxazine compounds and pharmaceutical use thereof
12/1989
12/12/1989US4886808 Indazolyl carboxylic acid amides useful for treating migraine clusters headache, trigeminal neuralgia or emesis
12/05/1989CA1263654A1 Zwitterionic bicyclic compounds and their salts, solvates, hydrates and esters
11/1989
11/21/1989US4882327 Certain heterocyclic N-substituted carboxamides
11/14/1989US4880802 Substituted basic 2-aminotetralin useful as cardiotonic agents
11/08/1989EP0340270A1 5-ht 3? receptor antagonists for treatment of cough and bronchoconstriction
11/02/1989WO1989010364A1 Dibenzofurancarboxamides
11/02/1989EP0339950A2 Dibenzofurancarboxamides, their use as pharmaceutical agents, a composition containing the same, and a process for the preparation thereof
10/1989
10/31/1989US4877794 2-Alkoxy-n-(1-azabicyclo(2.2.2)oct-3-yl) benzamide and thiobenzamide compositions and the use thereof to treat schizophrenia
10/31/1989US4877780 Antiemetic N-substituted benzamides
10/25/1989EP0338723A1 Novel compounds
10/19/1989DE3810552A1 Esters and amides of indole-, benzo[b]thiophene or benzo[b]furancarboxylic acids or 4-amino-2-methoxybenzoic acids with N-heterocyclic or N-heterobicyclic alcohols or amines, processes for their preparation, pharmaceutical compositions containing them and applicator for administration thereof
10/18/1989EP0337547A1 Spirocyclic compounds incorporating five-membered rings with two heteroatoms
10/05/1989WO1989009217A1 Novel compounds
10/03/1989US4871744 Certain 2,3-dihydro-indole-1-carboxamido-N-[8-azabicyclo(3.2.1)octan-3-yl]de
09/1989
09/26/1989US4870181 Process for the preparation of 2-alkoxy-N-(1-azabicyclo[2.2.2])octan-3-yl)aminobenzamides
09/20/1989EP0332647A1 New benzimidazole derivatives a process for production thereof and a pharmaceutical composition containing the same
09/06/1989EP0330826A2 Use of pyridin-2-ethers or pyridin-2-thioethers with a nitrogen-containing cycloaliphatic ring as agents with an antidepressant activity
09/05/1989US4863921 Gastrointestinal disorders
09/05/1989US4863919 Method of enhancing memory or correcting memory deficiency with arylamido(and arylthiomido)-azabicycloalkanes
08/1989
08/16/1989EP0328200A1 Five-membered ring systems with bonded azacyclic ring substituents
08/15/1989US4857535 Anti-spasmodic agents having a heterocyclic ring
08/15/1989US4857517 Gastrointestinal and nervous system disorders
08/09/1989EP0327335A1 Arylamido(and arylthioamido)-azabicycloalkanes for enhancing memory or correcting memory deficiency
08/09/1989EP0327155A2 Pyrazines, pyrimidines and pyridazines, useful in the treatment of senile dementia
08/08/1989US4855290 Derivatives of quinuclidine
08/01/1989US4853376 Gastrointestinal disorders
07/1989
07/25/1989US4851416 Berban derivatives as α2 -adrenergic antagonists
07/25/1989US4851407 Novel treatment
07/25/1989CA1257870A1 Benzoic acid piperidyl ester derivatives
07/13/1989WO1989006225A1 Ligand-accelerated catalytic asymmetric dihydroxylation
07/12/1989EP0323864A2 Lipophilic oxadiazoles
07/05/1989EP0323077A1 Heterocyclic compounds
07/05/1989CN1033629A Heterocyclic ring spiroring compounds and process for preparing same
07/04/1989US4845092 Of visceral pain in mammals, humans
06/1989
06/28/1989EP0322182A2 Azabicyclic compounds, process for their preparation and pharmaceutical compositions containing them
06/28/1989EP0322016A1 1,7-Annelated indolecarboxylic acid esters and -amides
06/27/1989US4843074 1-azabicyclo[2.2.2]octan-3-yl 2-aryl-3-azacyclo-2-hydroxypropionates and their quaternary salts
06/21/1989EP0320753A2 Derivatives of cyclic aminoacids, their preparation, compounds containing them, and their use
06/01/1989WO1989004660A1 5-ht3 receptor antagonists for treatment of cough and bronchoconstriction
05/1989
05/24/1989EP0316718A2 Azacyclic compounds and their preparation and use
05/10/1989EP0315390A2 Novel 4-oxobenzotriazines and 4-oxoquinazolines
05/03/1989EP0313974A1 N-substituted derivatives of 1-desoxynojirimycine and 1-desoxymannonojirimycine, process for their preparation and their use as pharmaceuticals
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