Patents
Patents for C07D 453 - Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids (5,704)
05/1992
05/30/1992CA2097190A1 Compounds and processes for preparing optically pure multicyclic oxy-containing ring compounds having at least two chiral centers
05/20/1992EP0486266A1 Heat resistant herapathite and process for producing the same
05/19/1992US5114947 Benzofuran-7-carboxamides as anxiolytic agents
05/12/1992US5112385 Useful in rice paddies
05/05/1992US5110828 Azabicyclo oxime derivatives
04/1992
04/28/1992USRE33907 Anti-spasmodic agents having a heterocyclic ring
04/21/1992US5106851 Benzofused-n-containing heterocycle derivatives
04/21/1992US5106843 Treatment of migraine, emesis, anxiety, gastrointestinal disorders, psychological disorders
04/15/1992EP0232328B1 Zwitterionic bicyclic compounds and their salts, solvates, hydrates and esters
04/01/1992EP0478363A2 Novel sulfonamide fibrinogen receptor antagonists
04/01/1992EP0478362A2 Fibrinogen receptor antagonists
04/01/1992CN1059908A Primidine derivatives and medicine
03/1992
03/28/1992CA2052043A1 Fibrinogen receptor antagonists
03/25/1992WO1992005146A1 Stereoselective preparation of acid sensitive amides and intermediates useful in said preparation
03/25/1992EP0477049A1 Amido-3-pyrazole derivatives, process for their preparation and pharmaceutical compositions containing them
03/25/1992CN1059724A Tricyclic compounds
03/25/1992CA2092179A1 Stereoselective preparation of acid sensitive amides and intermediates useful in said preparation
03/24/1992US5098909 5-ht3 receptor antagonists for treatment of cough and bronchoconstriction
03/24/1992US5098888 Cholinergic agents and antispasmodic agents
03/17/1992US5096901 Pharmacologically active amides and esters containing an azabicycloalkane moiety
03/07/1992WO1992004346A1 Antimuscarinic bronchodilators
03/05/1992WO1992003433A1 Heterocyclic compounds and their preparation and use
03/05/1992WO1991016322A3 Heterocyclic chiral ligands and method for catalytic asymmetric dihydroxylation of olefins
03/04/1992EP0473442A1 A substituted pyrazine and its salts, compositions containing them and their use in medicine
03/01/1992WO1992004347A1 Indole derivative and medicine
03/01/1992WO1992004333A1 Pyrimidine derivative and medicine
03/01/1992CA2090037A1 Indole derivatives and drugs
03/01/1992CA2090027A1 Pyrimidine derivatives and drugs
03/01/1992CA2050264A1 Substituted pyrazine and its salts, compositions containing them and their use in medicine
02/1992
02/25/1992US5091536 Soluble magnesium hydrides, method of preparing them, and use thereof
02/25/1992US5091397 1-aza-bicyclico(2.2.1)heptanes
02/18/1992CA1296004C Aza-indole derivatives
02/12/1992EP0470668A1 A process for preparing enantiomers of compounds having muscarinic activity
02/09/1992CA2048315A1 Process for preparing enantiomers of compounds having muscarinic activity
02/06/1992WO1992001675A2 Substituted bicyclic bis-aryl compounds exhibiting selective leukotriene b4 antagonist activity, their preparation and use in pharmaceutical compositions
02/05/1992EP0338010B1 Pharmaceutical compositions for treatment of hyperproliferate skin disease
02/05/1992CN1058405A 奎宁环衍生物 Quinuclidine derivatives
02/05/1992CN1058396A Diaminotrifluoromethylpyridine derivatives, process for their production and phospholipase a2 inhibitor containing them
02/04/1992US5086179 Process for the preparation of optically pure amides
02/01/1992CA2048178A1 Engineered antibodies
01/1992
01/29/1992EP0468054A1 Benzenesulfonamide derivative
01/28/1992US5084452 2-azabicyclo(2,2,2)octane-3-carboxylic acid derivatives for the treatment of disorders of the cerebral circulation
01/28/1992CA1294964C Berban derivatives as a -adrenergic antagonists
01/25/1992CA2087848A1 Substituted bicyclic bis-aryl compounds exhibiting selective leukotriene b4 antagonist activity, their preparation and use in pharmaceutical compositions
01/24/1992WO1992001688A1 Quinuclidine derivatives
01/22/1992EP0467709A2 Use of an ATP-sensitive potassium channel blocker to treat neuronal insult
01/21/1992US5082843 Pyrazinyl and pyridazinyl ethers
01/21/1992CA2044855A1 Method for treating insult to neurons prone to parkinson's degeneration employing an atp-sensitive potassium channel blocker
01/15/1992EP0465913A2 Diaminotrifluoromethylpyrimidine derivatives, process for their production and phospholipase A2 inhibitor containing them
01/14/1992CA1294281C Specific 5-ht--antagonists
01/07/1992US5079360 Processes for preparing bicyclic compounds and intermediates thereof
12/1991
12/25/1991CN1057259A Piperidyloxy-and quinuclidinyloxy-isoxazole derivatives, their preparation and their therapeutic use
12/17/1991US5073557 Cognition activators, stimulants of central muscarinic acetylc holine receptors
12/17/1991CA1293256C2 Substituted benzoic acid alkylene bridged pyridil derivatives
12/04/1991EP0459568A2 Substituted oxadiazoles and thiadiazoles for use in the treatment of glaucoma and novel compounds having such use
12/03/1991US5070095 Antianxiety agents
12/02/1991WO1991018899A1 3-amino-2-aryl quinuclidines, process for their preparation and pharmaceutical compositions containing them
12/01/1991CA2043385A1 Substituted oxadiazoles and thiadiazoles for use in the treatment of glaucoma and novel compounds having such use
11/1991
11/27/1991EP0458214A1 Bicyclic 1-azacycloalcanes
11/21/1991EP0457243A1 Novel tricyclic compounds
11/21/1991DE4116582A1 New bi:cyclic 1-aza-cycloalkane 5HT antagonists - for treating Alzheimer's disorders, and for improving memory
11/20/1991CA2042860A1 Bicyclic 1-aza-cycloalkanes
11/15/1991CA2042443A1 Tricyclic compounds
11/13/1991EP0456519A1 Piperidyloxy- and quinuclidinyloxy- isoxazole derivatives, their preparation and their therapeutic use
11/12/1991CA2042336A1 Piperidyloxy-and quinuclidinyloxy-isoxazole, derivatives, their preparation and their therapeutic use
11/05/1991US5063231 Gastrointestinal
11/05/1991US5063230 Substituted saturated and unsaturated indole quinoline and benzazepine carboxamides and their use as pharmacological agents
10/1991
10/31/1991WO1991016322A2 Heterocyclic chiral ligands and method for catalytic asymmetric dihydroxylation of olefins
10/28/1991WO1991017161A1 Isoquinoline amides and esters as 5 ht3 receptor antagonists
10/28/1991CA2081350A1 Isoquinoline amides and esters as 5 ht3 receptor antagonists
10/24/1991WO1991016888A1 Spiro[benzofurancycloalkane]carboxamides as 5ht3 antagonists
10/24/1991CA2081011A1 Spiro[benzofurancycloalkane]carboxamides as 5ht3 antagonists
10/16/1991EP0452101A2 Spiro bridged and unbridged heterocyclic compounds
10/09/1991EP0450757A2 Use of 5-hydroxytryptamine-antagonists in the treatment of mental disorders originating in childhood
10/09/1991EP0450345A1 Indole derivatives
10/08/1991US5055469 Antisecretory agents
10/03/1991WO1991014686A1 Azacyclic or azabicyclic compounds, their preparation and use
10/03/1991CA2078791A1 Azacyclic or azabicyclic compounds, their preparation and use
09/1991
09/25/1991CA2038908A1 Indole derivatives
09/19/1991WO1991013885A1 1-azabicyclic compounds, processes and pharmaceutical compositons containing them
09/17/1991US5049556 Certain N-azabicyclo-2,3-dihydro-indole-1-carboxamides having anti-emetic properties, further found useful in treating headaches, neuralgia and anxiety
09/17/1991US5049386 N-ω,(ω-1)-dialkyloxy)- and N-(ω,(ω-1)-dialkenyloxy)Alk-1-YL-N,N,N-tetrasubstituted ammonium lipids and uses therefor
09/11/1991EP0446078A1 Silver halide photographic materials
09/11/1991EP0445731A1 Azabicyclo and azacyclo oxime and amine cholinergic agents and pharmaceutically acceptable salts thereof
09/10/1991CA1288776C Process for the preparation of 2-alkoxy-n-(1- azabicyclo[2.2.2]octan-3-yl) aminobenzamides
09/10/1991CA1288774C 1,2-dialkoxy-w-trialkylammonium cationic surfactants
09/05/1991WO1991013071A1 Novel trisubstituted pyrrols, process for their production and medicaments containing these compounds
09/05/1991WO1991009593A3 5-ht3 antagonists for treatment of nausea, bradycardia of hypotension associated with myocardial instability
08/1991
08/29/1991DE4005969A1 Neue trisubstituierte pyrrole, verfahren zu ihrer herstellung sowie arzneimittel, die diese verbindungen enthalten New trisubstituted pyrroles, process for their production and with drug containing these compounds
08/20/1991US5041549 Heterocyclic spiro compounds and methods for preparing the same
08/20/1991US5041456 Pharmaceutically useful 3-(indol-3-yl)-1,2,4-oxa- and thiadiazoles substituted in the 5-position by an amino containing group
08/17/1991WO1991012254A1 Substituted urea compounds and their preparation and use
08/17/1991CA2074803A1 Substituted urea compounds and their preparation and use
08/09/1991WO1991012237A1 Benzenesulfonamide derivative
08/09/1991CA2050591A1 Benzenesulfonamide derivatives
08/07/1991CN1053607A Hiv protease inhibitors useful for treatment of aids
07/1991
07/30/1991US5036076 Use of 2-azabicyclo[2.2.2]octane-3-carboxylic acid derivatives for the treatment of migraine
07/24/1991EP0438311A2 Di- and tripeptide renin inhibitors
07/23/1991US5034398 1H-indazole-3-carboxamide-N-2-azabicyclo[2.2.2]octanes useful for treating anxiety, psychosis, neuralgia, migraine and cluster headaches
07/20/1991CA2034524A1 Di- and tripeptide renin inhibitors containing non-peptidal conformationally-constrained tripeptide mimic for leu10-val11-ile12
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