Patents for C07D 453 - Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids (5,704) |
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02/05/2003 | CN1100535C Pharmaceutical agents for treatment of emesis |
02/04/2003 | US6514977 For treating p38 kinase mediated disorders |
01/30/2003 | WO2003007949A1 Bridged piperidine derivatives as melanocortin receptor agonists |
01/29/2003 | EP1278758A1 Combretastatin a-1 phosphate and combretastatin b-1 phosphate prodrugs |
01/29/2003 | EP1278735A1 2,4-di(hetero-)arylamino(-oxy)-5-substituted pyrimidines as antineoplastic agents |
01/23/2003 | WO2003006371A1 N,n-dinitramide salts as solubilizing agents for biologically active agents |
01/23/2003 | WO2003006019A1 Medicinal composition for treatment of interstitial cystitis |
01/23/2003 | CA2453179A1 N,n-dinitramide salts as solubilizing agents for biologically active agents |
01/22/2003 | CN1099419C Azebicyclic compound |
01/16/2003 | WO2003004493A1 Novel compounds, their preparation and use |
01/16/2003 | US20030013876 Process for the synthesis of gonadotropin releasing hormone antagonists |
01/16/2003 | CA2448913A1 Sulfone containing bicyclic aromatic ring compounds, their preparation and use as nicotinic acetyl-chloine receptors |
01/15/2003 | EP0820451B1 Novel heterocyclic compounds |
01/09/2003 | US20030008867 Compounds |
01/08/2003 | EP1272182A2 Use of sabcomeline in the treatment of anxiety |
01/08/2003 | CN1390216A Polymorphsof crystalline (2-benzhycrryl-1-azabicyclo [2,2,2] oct-3-YC)-(5-isopropyl-2-methoxybenzyl)-ammoniumchloride as NK-1 receptor antagonists |
01/03/2003 | WO2003000682A1 (pyrimidyl)(phenyl)substituted fused heteroaryl p38 inhibiting and pkg kinase inhibiting compounds |
01/03/2003 | WO2002040058A3 Hydroxyapatite-targeting poly(ethylene glycol) and related polymers |
01/03/2003 | CA2450555A1 (pyrimidyl)(phenyl)substituted fused heteroaryl p38 inhibiting and pkg kinase inhibiting compounds |
01/02/2003 | US20030004208 Squalene synthetase inhibitors; antilipemic agents, anticholesterol agents |
01/02/2003 | EP1268470A1 Dual molecules containing a peroxide derivative, synthesis and therapeutic applications thereof |
01/02/2003 | EP1268051A2 Dosing form for reagents, use of said dosing form in organic chemical synthesis and production of said dosing form |
12/31/2002 | US6500840 Central nervous system disorders |
12/27/2002 | WO2002102766A2 Combretastatin a-3 prodrug |
12/27/2002 | CA2418102A1 Combretastatin a-3 prodrug |
12/24/2002 | CA2131019C Nitrosation process |
12/19/2002 | WO2002100858A2 Quinuclidine-substituted heteroaromatic compounds as ligands at nicotinic acetylcholine receptors |
12/19/2002 | US20020193405 For prophylaxis and therapy of diseases, such as cell proliferation or apoptosis mediated diseases |
12/19/2002 | CA2445471A1 Quinuclidine-substituted heteroaromatic compounds as ligands at nicotic acetylcholine receptors |
12/11/2002 | CN1384100A Benzo-1,3-dioxole and benzofuran substituted pentazane derivative |
12/10/2002 | US6492516 Pharmaceutically acceptable salts thereof which exhibit utility for the treatment of cytokine mediated diseases such as arthritis. |
12/10/2002 | US6492386 Treating a disease or condition in a mammal, wherein the alpha 7 nicotinic-acetylcholine receptor is implicated |
12/10/2002 | US6492385 Quinuclidine-substituted heteroaryl moieties for treatment of disease |
12/10/2002 | US6492355 Adamantane derivatives |
12/05/2002 | WO2002096855A2 Anticholinergic compounds and methods of use |
12/05/2002 | WO2002064124A3 Medicament formulation containing a muscarinic agonist |
12/05/2002 | CA2443346A1 Anticholinergic compounds and methods of use |
12/03/2002 | US6489477 Nmda nr2b antagonists. accordingly, another aspect of the invention is the treatment of pain, migraine, depression, anxiety, schizophrenia, parkinson's disease, or stroke--maladies that are amenable to amelioration through |
11/28/2002 | WO2002094790A1 Fused heterocyclic compound and medicinal use thereof |
11/27/2002 | EP1259512A1 Pteridine compounds for the treatment of psoriasis |
11/27/2002 | EP1259508A1 Novel biarylcarboxamides |
11/26/2002 | US6486172 Quinuclidine-substituted aryl compounds for treatment of disease |
11/21/2002 | WO2002022598A8 Quinolinone derivatives as tyrosine kinase inhibitors |
11/21/2002 | US20020173507 Antiproliferative agents; apoptosis; anticancer agents |
11/21/2002 | US20020173494 Ammonium salts of inositol hexaphosphate, and uses thereof |
11/20/2002 | EP0892780B1 M-AMIDINO PHENYL ANALOGS AS FACTOR Xa INHIBITORS |
11/20/2002 | EP0699199B1 Heteroatom substituted alkyl benzylaminoquinuclidines as substance p antagonists |
11/19/2002 | US6482834 Quinoline and quinoxaline compounds which inhibit platelet-derived growth factor and/or p56lck tyrosine kinases |
11/14/2002 | US20020169208 Oxybutynin analogs; antichloinergic agents; side effect reduction; short half-life; water-soluble metabolites; incontinence; mydriatic and bronchodilator agents; respiratory system disorders; antiperspirants |
11/13/2002 | EP1256573A1 Process for producing stereoisomer of pyrrolidine derivative |
11/13/2002 | EP1256568A1 Intermediates for the preparation of enantiomerically pure cyclopentane and cyclopentene beta amino acids |
11/12/2002 | US6479510 N-((2s,3r)-2-methyl-1-azabicyclo(2.2.2)oct-3-yl)-4-(4-hydroxyp henoxy)- benzamide for example; treating diseases of the alpha-7-nicotinic acetylcholine receptor i.e. schizophrenia, or psychosis |
11/12/2002 | US6479480 1h-indole derivatives bearing an optionally substituted phenyl moiety at the 2-position of the indole ring system and a methylene-linked heterocyclic moiety at the 3-position of the indole ring system; schizophrenia treatment |
11/07/2002 | WO2002088114A2 Heteroaryl ofefinic azacyclic and heteroaryl acetylenic azacyclic compounds for the treatment of cns disorders |
11/07/2002 | US20020165393 Kinetic resolutions of chiral 2- and 3-substituted carboxylic acids |
11/07/2002 | US20020165251 Such as 1-phenylsulfonyl-4-piperazinylindole hydrochloride for treatment or prophylaxis of disease mediated by serotonin related receptor, obesity, and/or central nervous system disorder |
11/06/2002 | EP1254123A1 2-benzothiazolyl urea derivatives and their use as protein kinase inhibitors |
11/06/2002 | EP1254115A2 Cannabinoid receptor modulators, their processes of preparation, and use of cannabinoid receptor modulators for treating respiratory and non-respiratory diseases |
11/06/2002 | EP0788473B1 Novel high enantio-selective process for producing pure enantiomeric cyclopentane and cyclopentene-beta-amino acids |
10/31/2002 | WO2002085901A1 Substituted azabicyclic moieties for the treatment of disease (nicotinic acethylcholine receptor agonists) |
10/31/2002 | WO2002085848A2 Synthesis of pancratistatin prodrugs |
10/31/2002 | WO2002053564A3 Quinuclidine derivatives and their use as m3 antagonists |
10/31/2002 | US20020161252 Zinc complex with a chiral ligand, such as diethylzinc((S,S)-N-N'-ethylene-bis-(1-phenylethylamine)) |
10/31/2002 | CA2444471A1 Synthesis of pancratistatin prodrugs |
10/31/2002 | CA2439960A1 Substituted azabicyclic moieties for the treatment of disease (nicotinic acethylcholine receptor antagonists) |
10/30/2002 | EP0799221B1 Quinazolines as inhibitors of endothelin converting enzyme |
10/30/2002 | CN1377349A Quiunclidine compounds and drugs containing the same as the active ingredient |
10/24/2002 | WO2002083670A1 Novel phase transfer catalyst and method for producing alpha-amino acid using the same |
10/24/2002 | US20020156095 Treatment of depression, anxiety, psychosis, obesity, pain, Parkinson's disease, Alzheimer's disease, neurodegenerative diseases, movement disorders, respiratory diseases, inflammatory diseases, neuropathy, immune disorders, etc. |
10/22/2002 | US6468998 Pyrrolidine compounds and medicinal utilization thereof |
10/17/2002 | WO2002081420A1 Cyclooctanone derivative and cyclodecanone derivative, and use thereof |
10/17/2002 | US20020151744 Kinetic resolutions of chiral 2-and-3-substituted carboxylic acids |
10/16/2002 | EP1248617A1 2-aza-bicyclo 2.2.2]octane nmda/nr2b antagonists |
10/16/2002 | EP0934316B1 Azabicyclic carbamoyloxy mutilin derivatives for antibacterial use |
10/15/2002 | US6465513 Multicyclic compounds which inhibit leukocyte adhesion mediated by VLA-4 |
10/15/2002 | US6465449 Heteroaromatic bicyclic derivatives useful as anticancer agents |
10/15/2002 | US6465437 Diphosphate salt of a 4″-substituted-9-deoxo-9A-AZA-9A- homoerythromycin derivative and its pharmaceutical composition |
10/09/2002 | CN1373760A Quinuclidine derivs. as muscarinic M3 receptors ligand and their use |
10/03/2002 | WO2002076981A1 Isoquinuclidine derivative, process for producing the same, and medicinal composition containing the same |
10/03/2002 | WO2002076975A1 Chemical derivatives and their use as anti-telomerase agent |
10/03/2002 | WO2002076973A1 N-aryl-substituted cyclic amine derivative and medicine containing the same as active ingredient |
10/03/2002 | WO2001023385A9 Novel tropane analogs |
10/03/2002 | WO2000034265A3 Quinoline-indole antimicrobial agents |
10/03/2002 | US20020143185 Nitrosation process |
10/03/2002 | CA2442012A1 Chemical derivatives and their use as anti-telomerase agent |
10/03/2002 | CA2441838A1 Isoquinuclidine derivatives, method of manufacturing the same and therapeutic agents containing these compounds |
10/02/2002 | CN1091768C Novel benzo-1,3-dioxolyl-and benzofuranyl substituted pyrrolidine derivatives as endothelin antagonists |
10/01/2002 | US6458985 Use of compressed CO2 in chemical reactions |
10/01/2002 | US6458948 Process for producing carboxylic acid derivative and condensing agent comprising quaternary ammonium salt |
10/01/2002 | CA2245857C 1,4-dihydropyridine compounds as bradykinin antagonists |
10/01/2002 | CA2241845C 4,5-dihydronaphth¬1,2-c|isoxazoles and derivatives thereof having cns activity |
10/01/2002 | CA2228370C Piperazino derivatives as neurokinin antagonists |
10/01/2002 | CA2089769C Heterocyclic compounds and their preparation and use |
09/26/2002 | WO2002024692A8 1-azabicyclo[2.2.2]octan-3-one derivatives and maleimide derivatives and their use for treating cancer tumors |
09/26/2002 | WO2002018334B1 Sodium channel modulators |
09/26/2002 | US20020137741 Use as topical antibiotics |
09/25/2002 | EP1243589A1 Heteroaryl-substituted pyrrole derivates, their preparation and their therapeutic uses |
09/25/2002 | EP1242396A1 New p2x 7 receptor antagonists for use in the treatment of inflammatory, immune or cardiovascular diseases |
09/25/2002 | EP0986390B1 Pharmaceutical compositions containing cinchonine dichlorhydrate |
09/25/2002 | EP0918521B1 Formulation for the treatment and/or prophylaxis of dementia |