Patents
Patents for C07C 405 - Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins (3,702)
03/1994
03/17/1994WO1994005631A1 9-chloroprostaglandin esters and amides and their use in the preparation of drugs
03/17/1994WO1994005619A1 4-hydroxy-2-cyclopentenone derivative and carcinostatic and osteogenesis promoter containing the same
03/08/1994US5292754 Treatment for hypertension or glaucoma in eyes
03/03/1994DE4229053A1 Pharmaceutical prepns. for promotion of skin circulation - contg. 9-chloro-prostaglandin derivs.
03/03/1994DE4229051A1 Pharmaceutical prepns. for treatment of elevated intraocular pressure - contg. 9-chloro-prostaglandin derivs.
03/03/1994DE4229050A1 New esters and amides of 9-chloro-prostaglandins - useful, e.g., in treatment of glaucoma and as diuretic agents
03/03/1994DE4229048A1 New ester(s) of 9-chloro-prostaglandin(s) - useful in treatment of glaucoma and as diuretic agents
03/01/1994US5290811 Use of 15-keto-prostaglandin compound for improvement of encephalic function
02/1994
02/24/1994DE4227790A1 Leukotriene B4 derivs. with a cyclohexane ring - with antiinflammatory, antiallergic, antiproliferative and antimycotic properties for treating e.g. eczema, asthma, colitis
02/22/1994US5288754 Polar C-1 esters of prostaglandins
02/22/1994US5288514 Linking a protected 2-aminobenzophenone to a substrate; deprotecting and reacting with an amino acid; cyclization; removal from substrate; screening
02/15/1994US5286889 Transmetalations from zirconium to copper intermediates
02/08/1994US5284858 Prostaglandins E and anti ulcers containing same
02/03/1994WO1994002457A1 Prostaglandin derivative
02/03/1994CA2140853A1 Prostaglandin derivatives
02/01/1994US5283349 2,6,7-trisubstituted-3-methylenebicyclo(3.3.0)-octanes, and process for production thereof
01/1994
01/18/1994CA1326238C Keto-reduction of carbacyclin intermediates
01/11/1994CA1326022C 6-oxoprostaglandin-e derivatives, method for their manufacture and their use as pharmaceuticals
01/11/1994CA1326021C Prostaglandin derivatives, their preparation and their therapeutic use
01/06/1994WO1993014743A3 Polar c-1 esters of prostaglandins
01/06/1994WO1992009573A3 Cyclopentane ether derivatives, methods for preparing them and their use in pharmaceuticals
12/1993
12/28/1993US5274130 Process for production of prostaglandin intermediates
12/23/1993WO1993026053A1 Micromechanical thermoelectric sensor element
12/15/1993EP0574185A2 PGE1 analogs
12/14/1993US5270049 2-decarboxyl-2-aminoalkyl-prostaglandins as ocular hypotensives
11/1993
11/10/1993EP0569046A1 Prostaglandin derivatives for the treatment of glaucoma or ocular hypertension
11/09/1993CA1324129C Prostaglandins of the f series
10/1993
10/26/1993US5256686 Phenylalkan(en)oic acid
10/20/1993EP0565730A1 Remedy for hepatic disease
10/19/1993CA1323364C Prostaglandins e and anti ulcer agents containing same
10/14/1993DE4139868A1 Leukotriene B4 derivs. with antiinflammatory and antiallergic properties
10/12/1993US5252763 Higher order cuprate complexes from alkyne, zirconocene chloride hydride, alkyllithium and cuprous cyanide
10/12/1993US5252605 Promotion of wound-healing with 15-keto-prostaglandin compounds
10/05/1993CA1322749C Prostaglandins of the d series, and tranquilizers and soporifics containing the same
09/1993
09/29/1993EP0562006A1 Homo-prostaglandin derivatives as ocular hypotensives
09/28/1993US5248788 Intermediates for prostaglandins
09/14/1993CA1322197C 9-halogen-(z) prostaglandin derivatives, process for their production and their use as pharmaceutical agents
08/1993
08/19/1993WO1993016041A1 Process for producing prostaglandin e
08/10/1993US5234953 9-Deoxy-2'9-methano-3-oxa-4,5,6-trinor-3,7'-(1'3-inter-phenylene) -13,14-dihydroprostaglandin F1; vasodilation
08/05/1993WO1993014743A2 Polar c-1 esters of prostaglandins
07/1993
07/08/1993WO1993013062A1 Halogenated tetraenyl prostaglandin derivatives
07/06/1993US5225439 Prostaglandins E and anti ulcers containing same
06/1993
06/29/1993US5223537 Method and composition for treatment of gastric and duodenal disorders
06/22/1993US5221799 New 15-dehydroxy-16-oxoprostaglandins
06/22/1993US5221763 13,14-dihydro-15-keto-PGFs and salts
06/22/1993US5221689 Stereospecific; hypotensive agents, anticoagulants
06/10/1993WO1993011105A1 Leukotriene-b4 derivatives, process for preparing the same and medicaments
06/10/1993CA2122992A1 Leukotriene-b derivatives, process for preparing the same and medicaments
06/09/1993EP0544899A1 Prostaglandins.
06/03/1993DE4139869A1 New cyclobutyl derivs. as leukotriene-5-B4 antagonists - used to treat contact dermatitis eczema, neuro-dermatitis etc.
06/01/1993US5216183 Antitumor, anticarcinogenic agents; bone formation accelerators
05/1993
05/26/1993CN1072408A Process for preparing 13, 14-dihydro-15(r)-17-phenyl-18'19'20-trinor-pgf 2 alpha esters
05/19/1993EP0541594A1 Cyclopentane derivatives, process for producing them and their pharmaceutical use.
05/19/1993EP0541593A1 Cyclopentane derivatives, process for producing them and their pharmaceutical use.
05/18/1993US5212200 Prostaglandins
04/1993
04/28/1993EP0340247B1 New process for the antipodal separation of bicyclo 3.3.0]octane-3,7-dion-2-carboxylic acid esters and their 7-monocetals
04/27/1993US5206416 Isocarbacyclin derivative
04/26/1993WO1993007876A1 Remedy for hepatic disease
04/20/1993US5204371 Cytoprotective agents
04/15/1993DE4134156A1 9-substituierte bicyclo(3.3.0)octan-derivate, verfahren zu ihrer herstellung und ihre pharmazeutische verwendung 9-substituted bicyclo (3.3.0) octane derivatives, process for their production and their pharmaceutical use
04/12/1993WO1993007118A1 9-substituted bicyclo[3.3.0]octane derivatives, for use as txa2 antagonists
04/12/1993CA2097930A1 9-substituted bicyclo[3.3.0]octane derivatives, for use as txa2 antagonists
04/06/1993US5200530 Keto reduction of carbacyclin intermediates
03/1993
03/17/1993EP0532218A1 Process for production of prostaglandin intermediates
03/10/1993EP0214975B1 Process for the determination of small quantities of drugs, body substances or other chemical substances in a biological material
03/02/1993US5190973 20-alkyl-7-oxoprostacyclin derivatives useful as pharmaceuticals
03/02/1993US5190964 5-fluorocarbacyclins, their preparation and pharmaceutical use
02/1993
02/16/1993US5187286 Antiinflammatory agents, antiallergens
02/04/1993WO1993001816A1 Method and composition for treatment of gastric and duodenal disorders and new pge2-derivatives
02/04/1993CA2114023A1 Method and composition for treatment of gastric and duodenal disorders and new pge2-derivatives
01/1993
01/19/1993US5180844 Chemical intermediates for prostaglandins
01/07/1993WO1993000329A1 Chemical process
01/05/1993US5177251 Halogenated tetraenyl prostaglandin derivatives
12/1992
12/29/1992US5175338 Isocarbacyclin derivatives and their pharmaceutically acceptable salts thereof
12/23/1992WO1992022334A1 Platelet receptor antagonists useful in detecting intravascular platelet aggregation
12/15/1992CA1311490C Process of preparing higher order cuprate complexes
12/09/1992EP0190233B1 New carbacyclines, preparation thereof and drug containing them
12/08/1992US5169960 Process for the production of E/Z mixtures of 2-(bicyclo[3.3.0]octan-3-ylidene)-acetic acid derivatives with predominant E or Z portion
12/02/1992EP0516181A1 Novel sulfonamide derivatives
12/02/1992EP0516180A1 Novel sulfonamide derivatives
12/01/1992US5168101 Hypotensives, anticoagulants, cardiovascular and brain disorders
11/1992
11/24/1992US5166382 Transmetalations from zirconium to copper intermediates
11/24/1992US5166369 Oxytocics or urogenital disorders
11/24/1992US5166178 Ocular hypotensive agents
11/24/1992US5166174 For duodenal ulcers or gastric ulcers
11/18/1992WO1992020648A1 Ocular hypotensive 2-decarboxyl-2-acylthioalkyl prostaglandin derivatives
11/18/1992CA2102295A1 Ocular hypotensive 2-decarboxyl-2-acylthioalkyl prostaglandin derivatives
11/17/1992US5164412 5-hetero-6-oxo-pge-derivatives
11/11/1992EP0213129B1 New 9-halogen-prostaglandine
11/10/1992US5162353 Carbacyclins, processes for their preparation, and their use as medicinal agents
10/1992
10/29/1992WO1992018472A1 Prostaglandin e1 analogue
10/29/1992WO1992010193A3 Homo-prostaglandin derivatives as ocular hypotensives
10/27/1992US5159102 7-thiaprostaglandins E, and process for producing same
10/23/1992WO1992018473A1 Prostaglandin e1 analogue
10/23/1992CA2109109A1 Prostaglandin e1 analogues
10/20/1992US5157052 Method for inhibiting ige production
10/20/1992US5157042 3-oxa-5-fluoro-carbacyclins, their preparation and use as medicinal agents
10/20/1992CA1309087C Cyclodextrin clathrates of carbacyclin derivatives and their use as medicinal agents
10/15/1992WO1992008465A3 2-decarboxyl-2-aminoalkyl-prostaglandins as ocular hypotensives
10/13/1992US5155104 Phenylalkan(en)oic acid
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