Patents
Patents for C07C 405 - Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins (3,702)
07/2009
07/22/2009CN101486699A Prostaglandin synthesis
06/2009
06/30/2009US7553875 to stimulate hair growth, restore hair color to depigmented hair, alopecia; side effects reduction; (16-(3-chlorophenoxy)-17,18,19,20-tetranor PGF2 alpha ) cyclopropyl amide
06/30/2009US7553874 Prostaglandin analog compositions and methods to treat epithelial-related conditions
06/25/2009WO2009078965A1 An improved process to prepare treprostinil, the active ingredient in remodulin®
06/25/2009CA2710205A1 An improved process to prepare treprostinil, the active ingredient in remodulin
06/23/2009US7550508 Prostaglandin analog compositions and methods to treat epithelial-related conditions
06/17/2009EP1871381B1 Therapeutic substituted cyclopentanones
06/17/2009EP1267883B1 Bile secretion promoting composition for liver transplantation containing a 15-keto-prostaglandin
06/11/2009WO2009073432A1 Substituted cyclopentanes having prostaglandin activity
06/11/2009CA2706879A1 Substituted cyclopentanes having prostaglandin activity
06/10/2009CN101454281A Prostaglandin ep4 agonists
06/02/2009US7541382 Prostaglandin analog compositions and methods to treat epithelial-related conditions
05/2009
05/06/2009EP2054540A2 Tagging reagents and methods for hydroxylated compounds
04/2009
04/21/2009CA2225761C Difluoroprostaglandin derivatives and their use
04/15/2009EP1694641B1 Prostaglandin synthesis
04/14/2009US7517912 to stimulate hair growth, restore hair color to depigmented hair, alopecia; side effects reduction; 17-phenyl trinor PGF2 alpha cyclopropyl methyl amide
04/08/2009EP2043993A2 Cyclopentane derivatives as antiglaucoma agents
04/07/2009US7514474 Prostaglandin analog compositions and methods to treat epithelial-related conditions
04/02/2009US20090088366 Nitrosated and nitrosylated prostaglandins, compositions and methods of use
03/2009
03/19/2009WO2009035565A1 Prostaglandin analogues for implant devices and methods
03/18/2009CN100469765C Prostaglandin nitrooxyderivatives
03/04/2009CN101379051A Method for preparing prostaglandin derivative
03/03/2009US7498458 Process for the preparation of prostaglandins and analogues thereof
02/2009
02/25/2009EP2027085A1 Prostaglandin ep4 agonists
02/25/2009EP1716113B1 Ep2- receptor agonists
02/11/2009EP2021322A2 Therapeutic cyclopentane derivatives
01/2009
01/29/2009US20090030076 Prostaglandin derivatives
01/27/2009CA2334355C Prostaglandin derivatives
01/22/2009US20090022787 Pharmaceutical composition comprising 11-deoxy- prostaglandin compound and method for stabilizing the compound
01/20/2009CA2364944C C16 unsaturated fp-selective prostaglandins analogs
01/08/2009WO2009006370A1 Therapeutic substituted cyclopentanes for reducing intraocular pressure
01/08/2009WO2009005172A1 Pharmaceutical combination of nsaid and prostaglandin compound
01/08/2009WO2009005171A1 Pharmaceutical combination of opioid and prostaglandin compound
01/08/2009CA2692572A1 Therapeutic substituted cyclopentanes for reducing intraocular pressure
01/08/2009CA2691107A1 Pharmaceutical combination of nsaid and prostaglandin compound
01/08/2009CA2691102A1 Pharmaceutical combination of opioid and prostaglandin compound
12/2008
12/11/2008WO2007123818A3 Organic nitric oxide enhancing salts of prostaglandins, compositions and methods of use
12/10/2008CN101318948A Lubiprostone1 crystal, preparation method and uses thereof
12/04/2008WO2008146105A1 Prostaglandin pharmaceutical compositions
12/02/2008US7459583 13,14-dihydro-16,16-difluoro-prostaglandin E1; cathartic inducing effect; halogenated bioactive lipid; for relieving or preventing constipation, cleansing the gastrointestinal tract; side effect reduction
12/02/2008CA2333038C Sleep-inducing preparation
11/2008
11/26/2008CN101312946A 9-chloro-15-deoxyprostaglandin derivatives, process for their preparation and their use as medicaments
11/11/2008US7449595 Nitrosated and nitrosylated prostaglandins, compositions and methods of use
11/11/2008US7449469 Improved pharmacological activity and tolerability; glaucoma; ocular hypertension
11/04/2008CA2229183C Endothelin antagonist
10/2008
10/29/2008EP1085012B1 Process for producing a purified prostaglandin derivative
10/22/2008EP1981867A2 Method for preparing prostaglandin derivative
10/02/2008US20080241078 Compositions and methods for treating hair loss using c16-c20 aromatic tetrahydro prostaglandins
09/2008
09/17/2008CN101265226A Compounds and methods for delivery of prostacyclin analogs
08/2008
08/27/2008EP1960353A2 Prostaglandins and analogues as agents for lowering intraocular pressure
08/06/2008CN100408039C 止痒剂 Antipruritics
08/05/2008US7407987 Compositions and methods for treating hair loss using C16-C20 aromatic tetrahydro prostaglandins
07/2008
07/31/2008WO2008091810A1 Substituted arylcylopentenes as therapeutic agents
07/31/2008CA2675632A1 Substituted arylcyclopentenes as therapeutic agents
07/10/2008WO2007140380A3 Tagging reagents and methods for hydroxylated compounds
07/08/2008US7396946 Compound for treatment of external secretion disorders
06/2008
06/19/2008US20080146821 Internal 1,15-Lactones Of Fluprostenol And Related Prostaglandin F2a Analogs And Their Use In The Treatment Of Glaucoma And Intraocular Hypertension
06/12/2008WO2007127639A3 Prodrug derivatives of acids using alcohols with homotopic hydroxy groups and methods for their preparation and use
06/05/2008US20080132543 Therapeutic and Delivery Methods of Prostaglandin Ep4, Agonists
05/2008
05/14/2008EP1920764A1 Fluprostenol isopropyl ester for use in the treatment of glaucoma and ocular hypertension
05/14/2008CN101180096A Method and composition for treating mucosal disorders
05/07/2008EP1917239A1 Fluoroprostaglandins nitroderivatives
04/2008
04/15/2008US7358275 cloprostenol or latanoprost; topical use; highly crystalline structures that are easy to formulate into ophthalmic solutions; The hydrolysis of these analogs releases only the active PGF2 alpha analog free acid, without the production of toxic and irritant small aliphatic alcohol coproducts
03/2008
03/20/2008US20080070978 cloprostenol or latanoprost; topical use; highly crystalline structures that are easy to formulate into ophthalmic solutions; hydrolysis of these analogs does not have toxic and irritant small aliphatic alcohol coproducts; hypotensive agent for intraocular pressure
03/19/2008EP1899295A2 Prostaglandin derivatives
03/06/2008WO2007140136A3 Therapeutic cyclopentane derivatives
03/06/2008WO2007000641A8 Prostaglandin derivatives
03/06/2008US20080058392 Prostaglandin derivatives
02/2008
02/27/2008EP1891005A2 Process for preparation of 13,14-dihydro-pgf2 alpha derivatives
02/27/2008EP1389116B1 Cathartic-inducing composition
02/21/2008US20080045596 Ep2 Receptor Agonists
02/13/2008EP1886992A1 Method for preparing prostaglandin derivative
02/07/2008US20080033036 Composition and Method for Promoting Hair Growth
01/2008
01/24/2008WO2007091697A3 Method for preparing prostaglandin derivative
01/16/2008CN101107225A 12-aryl prostaglandin analogs
01/02/2008EP1871381A2 Therapeutic substituted cyclopentanones
12/2007
12/27/2007WO2007130902A3 Therapeutic cyclopentane derivatives
12/12/2007CN101085756A Endothelin antagonist
12/06/2007CA2667854A1 Tagging reagents and methods for hydroxylated compounds
12/06/2007CA2652990A1 Therapeutic cyclopentane derivatives
12/05/2007EP1861169A2 Method and composition for treating mucosal disorders
12/04/2007US7304186 Synthetic method and novel chemical compounds
11/2007
11/28/2007EP1858592A2 Treatment of inflammatory bowel disease
11/15/2007CA2651045A1 Therapeutic cyclopentane derivatives
10/2007
10/11/2007WO2007115001A1 Prostaglandin ep4 agonists
10/11/2007CA2648159A1 Prostaglandin ep4 agonists
09/2007
09/25/2007US7273946 Nitroxy derivatives, e.g., 4-(nitrooxy)butyl [1R-[1 alpha (Z),2 alpha (R*),3 alpha ,5 alpha ]]-7-[3,5-dihydroxy-2-(3-hydroxy-5-phenylpentyl)cyclopentyl]-5-heptenoate; used for the treatment of glaucoma and ocular hypertension
09/20/2007US20070219256 Cyclopentane heptan(ene)oic acid, 2-thiocarbamoyloxy and 2-carbamoyloxy compounds as therapeutic agents
09/19/2007CN100337632C Endothelin antagonist
09/11/2007US7268239 Process for the preparation of prostaglandins and analogues thereof
08/2007
08/22/2007EP1819670A1 12-aryl prostaglandin analogs
08/16/2007CA2856659A1 Prostaglandin derivatives
08/16/2007CA2819844A1 Prostaglandin derivatives
08/16/2007CA2637797A1 Method for preparing prostaglandin derivative
08/08/2007EP1816121A1 9-Chloro-15-deoxyprostaglandin derivatives, process for their preparation and their use as medicaments
08/08/2007EP1814848A1 2,3,4-substituted-cyclopentanones as therapeutic agents
08/07/2007US7253295 Chloride channel opener
08/01/2007EP1812387A1 2,3,4-substituted cyclopentanones as therapeutic agents
07/2007
07/26/2007WO2007056087A8 Prostaglandins and analogues as agents for lowering intraocular pressure
07/25/2007EP1810967A1 Processes and intermediates for the preparations of prostaglandins
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