Patents
Patents for C07C 405 - Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins (3,702)
01/1985
01/29/1985CA1181747A1 Prostacyclin derivatives
01/16/1985EP0131441A2 5-Alkylidene-2-halo-4-substituted-2-cyclopentenone and process for production thereof
01/15/1985US4493846 Antiulcer, hypotensive, vasodilation, antiallergens, and anticoagulant agent
01/08/1985CA1180701A1 Prostacyclin derivatives and their manufacture and use
01/08/1985CA1180700A1 Prostaglandin 1 in2 xx derivatives and process for their production
12/1984
12/25/1984US4490555 9-Substituted carbacyclin analogs
12/25/1984US4490549 Enlarged-hetero-ring prostacyclin analogs
12/25/1984US4490548 Enlarged-hetero-ring prostacyclin analogs
12/25/1984US4490538 Enlarged-hetero-ring prostacyclin analogs
12/25/1984US4490537 Based on the cyclopenta /b/ pyran ring; anticoagulants; antiinflammatory agents;
12/20/1984WO1984004917A1 7-fluoroprostaglandins and process for their preparation
12/18/1984US4489092 Oxytocics, abortion
12/11/1984US4487961 Antiulcer, antiasthma, anticoagulants
12/11/1984US4487960 9-Substituted carbacyclin analogs
12/11/1984US4487953 Abortion
12/11/1984CA1179335A2 5Z-9-DEOXY-6,9-EPOXY-5-IODO-PGF 1N/.alpha. XX
12/04/1984US4486598 Antiulcer, anticoagulant, antiasthma
10/1984
10/30/1984US4479966 6,9-Methano-PGI2 analogues
10/30/1984US4479945 Inter-m-phenylene-prostacyclin analogues and use thereof in inhibiting blood platelet aggregation
10/17/1984EP0122019A2 A prostaglandin analogue
10/16/1984US4477684 11-Deoxy-11α-alkyl-PGE compounds from PGA compounds by lithium alkylation
10/16/1984US4477388 Vinylstannyl derivatives
10/09/1984CA1175822A1 2,5-inter-o-phenylene-3,4-dinor-pgf and pgi compounds
10/02/1984US4474979 Alkynylation with lithium cuprate compound
10/02/1984US4474966 19-Hydroxy-7a-homo-PGI1 and 19-hydroxy-19-methyl-7a-homo-PGI1 compounds
09/1984
09/26/1984EP0119949A1 Carbacyclins, process for their manufacture and their use as pharmaceutical compounds
09/25/1984US4473587 Prostaglandin E1 analogues
09/04/1984CA1173826A1 15-deoxy-16-hydroxy-16-substituted prostanoic acids and congeners
08/1984
08/28/1984US4468395 Prostaglandins and prostacyclins, processer for their preparation and their use as medicaments
08/21/1984US4466980 Thiaprostaglandin E1 derivatives, process for production thereof, and pharmaceutical use thereof
08/21/1984US4466914 Process for the conversion of primary and secondary alcohols to their corresponding thiols and thiol esters
08/15/1984EP0115954A2 Bicyclooctane derivatives and their production and use
08/15/1984EP0115844A1 3-Oxaprostaglandins
08/07/1984US4464388 Use of prostaglandin analogues to treat cytodamage
08/07/1984CA1172192A1 16-amino-prostaglandin derivatives, their acid addition salts and a process for the preparation thereof
08/02/1984WO1984002902A1 Prostacyclines and process for their preparation
07/1984
07/31/1984CA1171785A1 Method of inducing cytoprotection
07/24/1984US4461917 Prostaglandin analog
07/18/1984EP0113577A1 Process for preparing prostacyclins
07/18/1984EP0113561A2 Prostaglandin intermediates, their synthesis and their conversion to prostaglandins
07/11/1984EP0113311A1 5-Fluorocarbacyclins, process for their preparation and their use as medicines
07/04/1984EP0112633A2 Novel 5-thiaprostaglandin, process for production thereof, and pharmaceutical use thereof
07/04/1984EP0112451A2 Prostaglandin and hydroxylated fatty acid ester formulations
07/03/1984US4458091 Prostaglandins
06/1984
06/27/1984EP0111955A1 Prostaglandin intermediates
06/26/1984US4456768 Chemical synthesis
06/26/1984CA1169871A1 Process for the preparation of new heterocyclic compounds
06/19/1984US4455421 Antifertility, antiulcer agents; tetrazole derivatives
06/12/1984US4454339 9-Fluoroprostaglandin derivatives, and use as medicinal agents
06/05/1984US4452994 Complexing prostaglandins, steroids and subsequent decomposition
05/1984
05/29/1984US4451483 2,3,4-Trinor-m-inter-phenylene-prostaglandin derivatives and compositions and method for inhibiting blood platelet aggregation
05/29/1984CA1168155A1 Acetal stabilized prostaglandin compositions
05/16/1984EP0108451A2 Novel prostaglandin analogues
05/08/1984US4447428 Prostanoid compounds and pharmaceutical compositions
05/01/1984US4446147 Azaprostacyclins, their preparation and pharmaceutical use
04/1984
04/25/1984EP0106576A2 Novel 5-membered cyclic compounds, process for the production thereof, and pharmaceutical use thereof
04/24/1984US4444788 Pharmaceutically active 9-chloroprostaglandins
04/24/1984US4444691 11-Cyano-prostaglandins of the F-series
04/18/1984EP0105651A1 Bicyclo(3.3.0)octane derivatives
04/18/1984EP0105288A1 Carbacycline, preparation and utilization thereof.
04/17/1984US4443478 Prostaglandin analogues
04/04/1984EP0104631A2 Clavulone derivatives, process for preparing the same, and use of said compounds
03/1984
03/27/1984US4439365 Novel hydroxy substituted prostanoic acids, esters, congeners, intermediates and process
03/21/1984EP0103445A2 Process for production of prostaglandins E or F, and novel 7-(thiocarbo-acyloxy) prostaglandins E or F
03/20/1984US4438136 Prostaglandins
03/20/1984US4438132 4-Oxo-PGI2 compounds, their use in inhibition of thrombii and their production
03/20/1984US4438112 Prostaglandins, anticoagulants, antiasthma
03/20/1984US4438111 Prostaglandins, anticoagulants, antiasthma
03/13/1984US4436934 Synergistic combination with anagrelide; thromboxane synthetase inhibitors
03/13/1984CA1163586A1 16-amino-18,19,20-trinor-prostaglandin derivatives, acid addition salts and a process for the preparation thereof
03/07/1984EP0102230A2 Novel 6-nitroprostaglandin derivatives, process for production thereof, and use thereof
02/1984
02/22/1984EP0100900A1 Novel (3.2.0.) bicycloheptanone oxime ethers with valuable therapeutic properties
02/15/1984EP0100630A2 Prostaglandin E1 analogues
02/14/1984US4431833 Prostaglandin and hydroxylated fatty acid ester formulations
02/07/1984US4430345 6-aldoxime or ketoxime bicyclo(2,2,1)-neptanes for treatment of thrombosis
02/01/1984EP0099850A1 Novel carbacyclin esters, process for the preparation thereof, and their use as medicinal agents
02/01/1984EP0099673A2 Prostaglandin D derivatives, process for their preparation and compositions containing them
02/01/1984EP0099672A2 Trans-Delta 2-prostaglandin D derivatives, process for their preparation and compositions containing them
02/01/1984EP0099538A1 Carbacyclines, process for their preparation and their use as medicines
01/1984
01/31/1984US4429166 Cyclization of ketone with leaving group with base-generated carbanion
01/31/1984US4429148 Prostaglandins; bronchodilators, hyptotensives
01/24/1984US4427614 3-Hydroxybutyric acid polymers
01/18/1984EP0098794A1 Carbacyclines, process for their preparation and their use as medicines
01/18/1984EP0098793A1 Carbacycline amides, process for their preparation and their use as medicines
01/17/1984CA1160628A2 6-KETO AND 5-HEMIKETAL-PGF IN1.alpha. XX, METHYL ESTERS
01/17/1984CA1160627A1 9-deoxy-6,9-epoxyprostaglandins
01/11/1984EP0098141A2 Prostaglandin D analogues, process for their preparation and compositions containing them
01/10/1984US4425359 Antiulcer, luteolytic, abortion induction
01/10/1984US4425358 Anticoagulants, hypotensives
01/04/1984EP0097439A2 A crystalline prostaglandin salt
01/03/1984US4424374 Bicycloheptane derivatives
01/03/1984US4424350 2-Decarboxy-2-tetrazolyl-PGI2 compounds
01/03/1984CA1159821A1 Methylated prostaglandin derivatives
12/1983
12/28/1983EP0097023A2 Prostaglandin D derivatives, process for their preparation and compositions containing them
12/27/1983US4423068 (3.2.0) Bicycloheptanone oxime ethers with therapeutic properties
12/27/1983US4423067 Carbacyclins, their preparation and use
12/27/1983CA1159452A1 (5e)-9-deoxy-6,9-epoxy-prostaglandin derivatives
12/13/1983US4420632 Composition and process
11/1983
11/30/1983EP0094951A1 New prostacyclins and preparation method thereof.
11/29/1983US4418206 9-Deoxy-9-methylene derivatives of (dl)-16-phenoxy and 16-phenoxy substituted prostatriene compounds
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