Patents for C07C 405 - Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins (3,702) |
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03/02/2011 | EP1814848B9 2,3,4-substituted-cyclopentanones as therapeutic agents |
03/02/2011 | EP1417975B1 Remedies for diseases with bone mass loss having ep4 agonist as the active ingredient |
03/02/2011 | CN101085756B Endothelin antagonist |
02/22/2011 | CA2551409C Prostaglandin nitrooxyderivatives |
02/02/2011 | EP2279169A2 Therapeutic compounds |
02/01/2011 | CA2446994C Prostanoic acid derivatives as agents for lowering intraocular pressure |
02/01/2011 | CA2446386C 3, 7 or 3 and 7 thia or oxa prostanoic acid derivatives as agents for lowering intraocular pressure |
01/26/2011 | CN101959854A Substituted cyclopentanes having prostaglandin activity |
01/20/2011 | US20110015238 Blood flow promoters for cauda equina tissues |
01/20/2011 | CA2768154A1 Synthesis of prostanoids |
01/19/2011 | EP2275419A2 A lubiprostone crystal, its preparation process and its use |
01/19/2011 | EP2274279A1 Nitric oxide donating prostamides |
01/19/2011 | EP2274266A2 Process for the preparation of prostaglandin analogues and intermediates thereof |
01/13/2011 | WO2011005505A2 Method for the purification of prostaglandins |
01/13/2011 | US20110009370 Method to enhance tissue regeneration |
01/06/2011 | WO2010096123A3 Amino acid salts of prostaglandins |
01/05/2011 | EP1812387B1 2,3,4-substituted cyclopentanones as therapeutic agents |
01/04/2011 | CA2362132C Novel intermediate for the synthesis of prostaglandins |
12/29/2010 | EP2265576A1 Therapeutic substituted cyclopentanes |
12/22/2010 | EP2263674A1 10,10-dialkyl prostanoic acid derivatives as agents for lowering intraocular pressure |
12/22/2010 | CN1894209B Prostaglandin synthesis |
12/22/2010 | CN101921220A Remedies for diseases with bone mass loss having EP4 agonist as the active ingredient |
12/21/2010 | US7855226 Treatment of inflammatory bowel disease |
12/07/2010 | CA2492260C Prostaglandin derivatives |
12/07/2010 | CA2404767C Bile secretion promoting composition containing a 15-keto prostaglandin |
12/01/2010 | EP2255829A2 Pharmaceutical composition for treatment of diseases associated with decrease in bone mass comprising EP4 agonist as active ingredient |
12/01/2010 | CN101903324A Process to prepare treprostinil, the active ingredient in Remodulin |
11/24/2010 | EP2252570A1 An improved process to prepare treprostinil, the active ingredient in remodulin ® |
11/16/2010 | US7833995 Blood flow promoters for cauda equina tissues |
11/03/2010 | EP2245005A1 Substituted cyclopentanes having prostaglandin activity |
10/27/2010 | EP2243771A2 Composition and method for promoting hair growth |
09/30/2010 | WO2010109476A2 Improved process for the preparation of prostaglandins and analogues thereof |
09/29/2010 | EP2231162A1 Substituted cyclopentanes having prostaglandin activity |
09/28/2010 | CA2477080C Preparation of prostamides |
09/08/2010 | CN101827598A Pharmaceutical combination of opioid and prostaglandin compound |
09/02/2010 | WO2010097672A1 Process for the preparation of prostaglandin derivatives |
09/02/2010 | CA2751686A1 Process for the preparation of prostaglandin derivatives |
08/26/2010 | WO2010096123A2 Amino acid salts of prostaglandins |
08/26/2010 | CA2739571A1 Amino acid salts of prostaglandins |
08/10/2010 | US7772278 Nitrosated and nitrosylated prostaglandins, compositions and methods of use |
08/04/2010 | CN101795692A Therapeutic substituted cyclopentanes for reducing intraocular pressure |
07/28/2010 | EP1814848B1 2,3,4-substituted-cyclopentanones as therapeutic agents |
07/27/2010 | US7763652 such as 9-Deoxy-9 beta -chloro-16,17,18,19,20-pentanor-15-cyclohexyl-2,2,3,3,13,14-hexadehydro-6-thia-prostaglandin F1, useful as drugs for sleep induction |
07/22/2010 | WO2009078965A8 An improved process to prepare treprostinil, the active ingredient in remodulin® |
07/21/2010 | EP2208724A1 Process for purification of latanoprost, synthetic analogue of prostaglandin PGF 2alfa |
07/01/2010 | US20100168216 Prostaglandin pharmaceutical compositions |
06/16/2010 | CN1867310B Composition and method for promoting hair growth |
06/09/2010 | CN101721708A ED-71 preparation |
05/27/2010 | US20100130507 Prostaglandin derivatives |
05/12/2010 | CN101704777A Method for removing trans isomers with double bond at 5,6-positions from prost compounds |
04/07/2010 | EP2170819A1 Prostaglandin pharmaceutical compositions |
04/07/2010 | EP2170345A1 Therapeutic substituted cyclopentanes for reducing intraocular pressure |
03/31/2010 | CN101686984A Pharmaceutical combination of nsaid and prostaglandin compound |
03/09/2010 | US7674921 cloprostenol or latanoprost; topical use; highly crystalline structures that are easy to formulate into ophthalmic solutions; hydrolysis of these analogs releases only the active PGF2 alpha analog free acid, without the production of toxic and irritant small aliphatic alcohol coproducts |
03/04/2010 | US20100056808 Prostaglandin synthesis and intermediates for use therein |
03/04/2010 | US20100056807 Prostaglandin synthesis and intermediates for use therein |
03/02/2010 | CA2292836C Prostaglandin pharmaceutical compositions |
02/28/2010 | CA2639240A1 Prostaglandin synthesis and intermediates for use therein |
02/25/2010 | US20100048945 Process for the acylation of organic hydroxy compounds |
01/14/2010 | US20100010239 Process for the Production of Prostaglandins and Prostaglandin Analogs |
01/14/2010 | US20100010222 Pharmaceutical composition for treatment of diseases associated with decrease in bone mass comprising ep4 agonist as active ingredient |
01/13/2010 | EP2143712A1 Improved Process for the Production of Prostaglandins and Prostaglandin Analogs |
01/13/2010 | EP1211242B1 Prostaglandin derivatives |
12/17/2009 | WO2009132093A3 Substituted arylcyclopentenes as therapeutic agents |
12/08/2009 | US7629345 Improved pharmacological activity and tolerability; glaucoma; ocular hypertension |
12/01/2009 | CA2384718C Prostaglandin derivatives |
11/26/2009 | WO2009142967A1 Therapeutic prostaglandin compounds used as ocular hypotensive agents |
11/26/2009 | CA2724474A1 Therapeutic prostaglandin compounds used as ocular hypotensive agents |
11/19/2009 | US20090285786 Method to modulate hematopoietic stem cell growth |
11/12/2009 | WO2009137413A1 Therapeutic cyclopentane derivatives |
11/12/2009 | WO2009137411A1 Therapeutic compounds |
11/12/2009 | WO2009136281A1 Nitric oxide donating prostamides |
11/12/2009 | WO2009117467A3 Therapeutic compounds |
11/12/2009 | CA2728227A1 Therapeutic cyclopentane derivatives |
11/12/2009 | CA2723704A1 Nitric oxide donating prostamides |
11/11/2009 | EP2114875A1 Substituted arylcylopentenes as therapeutic agents |
10/29/2009 | WO2009132093A2 Substituted arylcyclopentenes as therapeutic agents |
10/29/2009 | WO2009131977A1 Therapeutic compounds |
10/29/2009 | CA2731279A1 Therapeutic compounds |
10/29/2009 | CA2722403A1 Substituted arylcyclopentenes as therapeutic agents |
10/27/2009 | US7608637 Prevention and treatment of bone disorders with EP4 agonistfor compounds posessing prostaglandins structure |
10/14/2009 | CN101555221A Producing method of prostaglandin F-type derivant |
10/14/2009 | CN100548977C Prostaglandin-like compound and its uses for treatment of external secretion disorders |
10/08/2009 | WO2009121228A2 A lubiprostone crystal, its preparation process and its use |
10/08/2009 | US20090252685 High penetration prodrug compositions of prostaglandins and related compounds |
09/24/2009 | WO2009117467A2 Therapeutic compounds |
09/24/2009 | WO2009117388A1 Therapeutic substituted cyclopentanes |
09/24/2009 | CA2718900A1 Therapeutic substituted cyclopentanes |
09/24/2009 | CA2718713A1 Therapeutic compounds |
09/22/2009 | CA2454584C Pharmaceutical composition for treatment of diseases associated with decrease in bone mass comprising ep4 agonist as active ingredient |
09/17/2009 | WO2009114467A1 Therapeutic cyclopentane derivatives |
09/15/2009 | CA2336952C 5-thia-.omega.-substituted phenyl-prostaglandin e derivatives, process for producing the same and drugs containing the same as the active ingredient |
09/10/2009 | US20090227672 Non-acidic cyclopentane heptanoic acid, 2-cycloalkyl or arylalkyl derivatives as therapeutic agents |
09/08/2009 | US7585889 cloprostenol or latanoprost; topical use; highly crystalline structures that are easy to formulate into ophthalmic solutions; hydrolysis of these analogs does not have toxic and irritant small aliphatic alcohol coproducts; hypotensive agent for intraocular pressure |
08/26/2009 | EP1553083B1 Prostaglandin derivatives |
08/13/2009 | WO2009100057A1 Substituted cyclopentanes having prostaglandin activity |
08/13/2009 | CA2713958A1 Substituted cyclopentanes having prostaglandin activity |
08/06/2009 | US20090197962 Substituted cyclopentanes having prostaglandin activity |
08/05/2009 | EP2084124A1 Positively charged water-soluble prodrugs of prostaglandins and related compounds with very high skin penetration rates |
08/04/2009 | CA2221110C Cyclopentane heptan(ene)oic acid, 2-heteroarylalkenyl derivatives as therapeutic agents for the treatment of ocular hypertension |