Patents
Patents for C07C 405 - Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins (3,702)
03/2011
03/02/2011EP1814848B9 2,3,4-substituted-cyclopentanones as therapeutic agents
03/02/2011EP1417975B1 Remedies for diseases with bone mass loss having ep4 agonist as the active ingredient
03/02/2011CN101085756B Endothelin antagonist
02/2011
02/22/2011CA2551409C Prostaglandin nitrooxyderivatives
02/02/2011EP2279169A2 Therapeutic compounds
02/01/2011CA2446994C Prostanoic acid derivatives as agents for lowering intraocular pressure
02/01/2011CA2446386C 3, 7 or 3 and 7 thia or oxa prostanoic acid derivatives as agents for lowering intraocular pressure
01/2011
01/26/2011CN101959854A Substituted cyclopentanes having prostaglandin activity
01/20/2011US20110015238 Blood flow promoters for cauda equina tissues
01/20/2011CA2768154A1 Synthesis of prostanoids
01/19/2011EP2275419A2 A lubiprostone crystal, its preparation process and its use
01/19/2011EP2274279A1 Nitric oxide donating prostamides
01/19/2011EP2274266A2 Process for the preparation of prostaglandin analogues and intermediates thereof
01/13/2011WO2011005505A2 Method for the purification of prostaglandins
01/13/2011US20110009370 Method to enhance tissue regeneration
01/06/2011WO2010096123A3 Amino acid salts of prostaglandins
01/05/2011EP1812387B1 2,3,4-substituted cyclopentanones as therapeutic agents
01/04/2011CA2362132C Novel intermediate for the synthesis of prostaglandins
12/2010
12/29/2010EP2265576A1 Therapeutic substituted cyclopentanes
12/22/2010EP2263674A1 10,10-dialkyl prostanoic acid derivatives as agents for lowering intraocular pressure
12/22/2010CN1894209B Prostaglandin synthesis
12/22/2010CN101921220A Remedies for diseases with bone mass loss having EP4 agonist as the active ingredient
12/21/2010US7855226 Treatment of inflammatory bowel disease
12/07/2010CA2492260C Prostaglandin derivatives
12/07/2010CA2404767C Bile secretion promoting composition containing a 15-keto prostaglandin
12/01/2010EP2255829A2 Pharmaceutical composition for treatment of diseases associated with decrease in bone mass comprising EP4 agonist as active ingredient
12/01/2010CN101903324A Process to prepare treprostinil, the active ingredient in Remodulin
11/2010
11/24/2010EP2252570A1 An improved process to prepare treprostinil, the active ingredient in remodulin ®
11/16/2010US7833995 Blood flow promoters for cauda equina tissues
11/03/2010EP2245005A1 Substituted cyclopentanes having prostaglandin activity
10/2010
10/27/2010EP2243771A2 Composition and method for promoting hair growth
09/2010
09/30/2010WO2010109476A2 Improved process for the preparation of prostaglandins and analogues thereof
09/29/2010EP2231162A1 Substituted cyclopentanes having prostaglandin activity
09/28/2010CA2477080C Preparation of prostamides
09/08/2010CN101827598A Pharmaceutical combination of opioid and prostaglandin compound
09/02/2010WO2010097672A1 Process for the preparation of prostaglandin derivatives
09/02/2010CA2751686A1 Process for the preparation of prostaglandin derivatives
08/2010
08/26/2010WO2010096123A2 Amino acid salts of prostaglandins
08/26/2010CA2739571A1 Amino acid salts of prostaglandins
08/10/2010US7772278 Nitrosated and nitrosylated prostaglandins, compositions and methods of use
08/04/2010CN101795692A Therapeutic substituted cyclopentanes for reducing intraocular pressure
07/2010
07/28/2010EP1814848B1 2,3,4-substituted-cyclopentanones as therapeutic agents
07/27/2010US7763652 such as 9-Deoxy-9 beta -chloro-16,17,18,19,20-pentanor-15-cyclohexyl-2,2,3,3,13,14-hexadehydro-6-thia-prostaglandin F1, useful as drugs for sleep induction
07/22/2010WO2009078965A8 An improved process to prepare treprostinil, the active ingredient in remodulin®
07/21/2010EP2208724A1 Process for purification of latanoprost, synthetic analogue of prostaglandin PGF 2alfa
07/01/2010US20100168216 Prostaglandin pharmaceutical compositions
06/2010
06/16/2010CN1867310B Composition and method for promoting hair growth
06/09/2010CN101721708A ED-71 preparation
05/2010
05/27/2010US20100130507 Prostaglandin derivatives
05/12/2010CN101704777A Method for removing trans isomers with double bond at 5,6-positions from prost compounds
04/2010
04/07/2010EP2170819A1 Prostaglandin pharmaceutical compositions
04/07/2010EP2170345A1 Therapeutic substituted cyclopentanes for reducing intraocular pressure
03/2010
03/31/2010CN101686984A Pharmaceutical combination of nsaid and prostaglandin compound
03/09/2010US7674921 cloprostenol or latanoprost; topical use; highly crystalline structures that are easy to formulate into ophthalmic solutions; hydrolysis of these analogs releases only the active PGF2 alpha analog free acid, without the production of toxic and irritant small aliphatic alcohol coproducts
03/04/2010US20100056808 Prostaglandin synthesis and intermediates for use therein
03/04/2010US20100056807 Prostaglandin synthesis and intermediates for use therein
03/02/2010CA2292836C Prostaglandin pharmaceutical compositions
02/2010
02/28/2010CA2639240A1 Prostaglandin synthesis and intermediates for use therein
02/25/2010US20100048945 Process for the acylation of organic hydroxy compounds
01/2010
01/14/2010US20100010239 Process for the Production of Prostaglandins and Prostaglandin Analogs
01/14/2010US20100010222 Pharmaceutical composition for treatment of diseases associated with decrease in bone mass comprising ep4 agonist as active ingredient
01/13/2010EP2143712A1 Improved Process for the Production of Prostaglandins and Prostaglandin Analogs
01/13/2010EP1211242B1 Prostaglandin derivatives
12/2009
12/17/2009WO2009132093A3 Substituted arylcyclopentenes as therapeutic agents
12/08/2009US7629345 Improved pharmacological activity and tolerability; glaucoma; ocular hypertension
12/01/2009CA2384718C Prostaglandin derivatives
11/2009
11/26/2009WO2009142967A1 Therapeutic prostaglandin compounds used as ocular hypotensive agents
11/26/2009CA2724474A1 Therapeutic prostaglandin compounds used as ocular hypotensive agents
11/19/2009US20090285786 Method to modulate hematopoietic stem cell growth
11/12/2009WO2009137413A1 Therapeutic cyclopentane derivatives
11/12/2009WO2009137411A1 Therapeutic compounds
11/12/2009WO2009136281A1 Nitric oxide donating prostamides
11/12/2009WO2009117467A3 Therapeutic compounds
11/12/2009CA2728227A1 Therapeutic cyclopentane derivatives
11/12/2009CA2723704A1 Nitric oxide donating prostamides
11/11/2009EP2114875A1 Substituted arylcylopentenes as therapeutic agents
10/2009
10/29/2009WO2009132093A2 Substituted arylcyclopentenes as therapeutic agents
10/29/2009WO2009131977A1 Therapeutic compounds
10/29/2009CA2731279A1 Therapeutic compounds
10/29/2009CA2722403A1 Substituted arylcyclopentenes as therapeutic agents
10/27/2009US7608637 Prevention and treatment of bone disorders with EP4 agonistfor compounds posessing prostaglandins structure
10/14/2009CN101555221A Producing method of prostaglandin F-type derivant
10/14/2009CN100548977C Prostaglandin-like compound and its uses for treatment of external secretion disorders
10/08/2009WO2009121228A2 A lubiprostone crystal, its preparation process and its use
10/08/2009US20090252685 High penetration prodrug compositions of prostaglandins and related compounds
09/2009
09/24/2009WO2009117467A2 Therapeutic compounds
09/24/2009WO2009117388A1 Therapeutic substituted cyclopentanes
09/24/2009CA2718900A1 Therapeutic substituted cyclopentanes
09/24/2009CA2718713A1 Therapeutic compounds
09/22/2009CA2454584C Pharmaceutical composition for treatment of diseases associated with decrease in bone mass comprising ep4 agonist as active ingredient
09/17/2009WO2009114467A1 Therapeutic cyclopentane derivatives
09/15/2009CA2336952C 5-thia-.omega.-substituted phenyl-prostaglandin e derivatives, process for producing the same and drugs containing the same as the active ingredient
09/10/2009US20090227672 Non-acidic cyclopentane heptanoic acid, 2-cycloalkyl or arylalkyl derivatives as therapeutic agents
09/08/2009US7585889 cloprostenol or latanoprost; topical use; highly crystalline structures that are easy to formulate into ophthalmic solutions; hydrolysis of these analogs does not have toxic and irritant small aliphatic alcohol coproducts; hypotensive agent for intraocular pressure
08/2009
08/26/2009EP1553083B1 Prostaglandin derivatives
08/13/2009WO2009100057A1 Substituted cyclopentanes having prostaglandin activity
08/13/2009CA2713958A1 Substituted cyclopentanes having prostaglandin activity
08/06/2009US20090197962 Substituted cyclopentanes having prostaglandin activity
08/05/2009EP2084124A1 Positively charged water-soluble prodrugs of prostaglandins and related compounds with very high skin penetration rates
08/04/2009CA2221110C Cyclopentane heptan(ene)oic acid, 2-heteroarylalkenyl derivatives as therapeutic agents for the treatment of ocular hypertension
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