| Patents for C07C 405 - Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins (3,702) |
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| 09/07/2005 | CN1665782A Prostaglandin derivatives |
| 09/01/2005 | US20050192451 stereospecific alkyl halide containing 15S-alcohol group such as (S)-3-(protected hydroxy)-5-(bromo or iodo)-1-phenyl pentane; novel chemical intermediate |
| 08/09/2005 | US6927300 Process for the preparation of Latanoprost |
| 07/28/2005 | WO2005068421A1 Prostaglandin nitrooxyderivatives |
| 07/28/2005 | US20050164992 Treating inflammatory bowel disease by administering prostaglandin derivatives such as (3-{(1R,4S,5S)-5-(3-chloro-benzo[b]thiophen-2-yl)-3-hydroxy-pent-1-enyl]-4-hydroxy-3,3-dimethyl-2-oxo-cyclopentylsulfanyl}-propylsulfanyl)-acetic acid methyl ester |
| 07/14/2005 | US20050154220 Particularly Latanoprost; 1,4 addition of a cuprate reagent of a protected 5-iodo-3-hydroxy-4-pentenylbenzene; stereoselective reduction; protection of hydroxyl groups; dihydroxylation; reduction; diol cleavage; Wittig reaction: esterification or amidation; and deprotection; intermediates |
| 07/13/2005 | EP1553083A1 Prostaglandin derivatives |
| 07/13/2005 | CN1639117A Preparation of prostamides |
| 07/07/2005 | WO2005061449A1 Ep2 receptor agonists |
| 06/30/2005 | WO2005058812A2 Prostaglandin synthesis |
| 06/30/2005 | CA2854783A1 Prostaglandin synthesis |
| 06/30/2005 | CA2549056A1 Prostaglandin synthesis |
| 06/22/2005 | CN1206976C Compositions and method for treating hair loss using C16-C20 aromatic tetrahydro prostaglandins |
| 06/16/2005 | WO2005053707A1 Blood flow promoters for cauda equina tissues |
| 06/09/2005 | US20050124588 2-Decarboxy-2-phosphinico prostaglandin derivatives and methods for their preparation and use |
| 06/09/2005 | US20050124587 2-Decarboxy-2-phosphinico prostaglandin derivatives and methods for their preparation and use |
| 06/02/2005 | WO2005049558A1 Novel prostamides for the treatment of glaucoma and related diseases |
| 06/02/2005 | CA2546013A1 Novel prostamides for the treatment of glaucoma and related diseases |
| 05/31/2005 | CA2324343C C11 oxymyl and hydroxylamino prostaglandins useful as medicaments |
| 05/25/2005 | EP1066254B1 C11 oxymyl and hydroxylamino prostaglandins useful as fp agonists |
| 05/19/2005 | US20050107477 Synthetic method and novel chemical compounds |
| 05/19/2005 | US20050107463 Novel prostamides for the treatment of glaucoma and related diseases |
| 05/17/2005 | US6894175 Drugs, cosmetics |
| 05/17/2005 | CA2147502C Novel 7-(5-substituted cyclopentyl) and (5-substituted cyclopentenyl) heptyl alcohols, heptylamines and heptanoic acid amides, and method of lowering intraocular pressure in the eye of a mammal by administration of these novel compounds |
| 05/10/2005 | CA2303801C Aromatic c16-c20-substituted tetrahydro prostaglandins useful as fp agonists |
| 04/13/2005 | CN1196678C Prostaglandin E1 derivatives |
| 04/05/2005 | US6875787 Vision defects; reducing pressure in eyes |
| 03/24/2005 | WO2005026109A1 Cyclopentane heptan(ene)oic acid, 2-thiocarbamoyloxy and carbamoyloxy compounds as therapeutic agents |
| 03/24/2005 | CA2537794A1 Cyclopentane heptan(ene)oic acid, 2-thiocarbamoyloxy and carbamoyloxy compounds as therapeutic agents |
| 03/16/2005 | EP1514548A2 Use of cloprostenol fluprostenol, and their analogues to treat glaucoma and ocular hypertension |
| 03/16/2005 | EP1097922B1 5-thia-omega-substituted phenyl-prostaglandin e derivatives, process for producing the same and drugs containing the same as the active ingredient |
| 03/10/2005 | US20050054689 prostaglandin derivatives such as (Z)-7-((1R,2S,3R)-2-Butylcarbamoyloxymethyl-3-hydroxy-5-oxo-cyclopentyl)-hept-5-enoic acid methyl ester, administering to mammals for treatment of ocular hypertension; hypotensive agents |
| 02/23/2005 | CN1190417C Prostaglandin Derivatives |
| 02/17/2005 | WO2005013928A1 Composition and method for promoting hair growth |
| 02/17/2005 | US20050038123 Process and intermediates to prepare latanoprost |
| 02/17/2005 | CA2534645A1 Composition and method for promoting hair growth |
| 02/15/2005 | CA2303764C Aromatic c16-c20-substituted tetrahydro prostaglandins useful as fp agonists |
| 02/08/2005 | US6852880 Preparing a 4-(6-carboxy-2-hexenyl)-5-(3-hydroxy-optionally substituted alkyl)-1,3-cyclopentanediol from an alkyl halide containing 15S-alcohol and a 2-(6-carboxy-2-hexenyl)-4-protected hydroxycyclopent-2-ene-1-one |
| 01/27/2005 | US20050020686 Remedies for diseases with bone mass loss having ep4 agonist as the active ingredient |
| 01/26/2005 | EP1385819A4 Process for preparing prostaglandin derivatives and stereospecific starting material thereof |
| 01/26/2005 | EP0943607B1 Process for the preparation of prostaglandins |
| 12/22/2004 | EP1487772A2 Cyclopentenone derivatives, their preparation and use in medicine |
| 12/09/2004 | US20040249172 Process for the preparationof prostaglandins and analogues thereof |
| 12/01/2004 | EP1480949A2 Preparation of prostamides |
| 11/25/2004 | US20040235958 10,10-dialkyl prostanoic acid derivatives as agents for lowering intraocular pressure |
| 11/24/2004 | EP1159265B1 C-16 unsaturated fp-selective prostaglandins analogs |
| 11/23/2004 | US6822112 Prostaglandin derivatives |
| 11/03/2004 | EP1159266B1 C-16 unsaturated fp-selective prostaglandins analogs |
| 11/03/2004 | CN1173945C 5-thia-omega-substituted phenyl-prostaglandin E derivatives, process for producing same and drugs containing same as active ingredient |
| 10/26/2004 | CA2040468C Process for preparing prostaglandin analogs using organozirconium compounds |
| 10/21/2004 | WO2003074481A8 Preparation of prostamides |
| 10/14/2004 | WO2004087724A1 PROCESS FOR PRODUCING α,ß,Ϝ-SUBSTITUTED CYCLOPENTANONE DERIVATIVE |
| 10/13/2004 | CN1170817C 前列腺素e类似物 E prostaglandin analogs |
| 10/07/2004 | US20040198817 Use of cloprostenol and fluprostenol analogues to treat glaucoma and ocular hypertension |
| 09/29/2004 | CN1533385A Process for preparation of prostaglandins and analogues thereof |
| 09/29/2004 | CN1533372A Process and intermediates to prepare latanoprost |
| 09/02/2004 | WO2004074240A1 Prostaglandin derivatives |
| 09/02/2004 | US20040171873 Process for the preparation of 17-phenyl-18,19,20-thinor-pgf 2a and its derivatives |
| 08/26/2004 | WO2004071428A2 10,10-dialkyl prostanoic acid derivatives as agents for lowering intraocular pressure |
| 08/26/2004 | US20040167190 Prostagladin derivatives for the treatment of glaucoma or ocular hypertension |
| 08/26/2004 | CA2515631A1 10,10-dialkyl prostanoic acid derivatives as agents for lowering intraocular pressure |
| 08/12/2004 | US20040157901 Vision defects; reducing pressure in eyes |
| 08/11/2004 | CN1161362C Novel intermediate for synthesis of prostaglandins |
| 08/10/2004 | CA2150287C Agent for treating hepato-biliary diseases |
| 07/20/2004 | US6765117 Preparing 9-deoxy-pgf1-type compounds, less steps; cyclization of an intermediate comprising a benzene substituted with a triple bond and a double bond |
| 07/07/2004 | EP1012136B1 Aromatic c 16?-c 20?-substituted tetrahydro prostaglandins useful as fp agonists |
| 06/30/2004 | EP1082299B1 C11 oxymyl and hydroxylamino prostaglandins useful as medicaments |
| 06/30/2004 | CN1509176A Cathartic composition |
| 06/24/2004 | US20040122102 compounds are potent ocular hypotensives, and are suitable for the management of glaucoma; they also are smooth muscle relaxants with broad application in systemic hypertensive and pulmonary diseases, gastrointestinal, reproduction disorders etc |
| 06/17/2004 | US20040116693 Process for preparing prostalglandin derivatives and stereospecific starting material thereof |
| 06/16/2004 | EP0695741B1 7-thiaprostaglandins and process for producing the same |
| 06/03/2004 | WO2003074481A3 Preparation of prostamides |
| 05/27/2004 | WO2004043471A1 Antipruritic drug |
| 05/26/2004 | EP1420794A1 Prostaglandin analogs as chloride channel opener |
| 05/25/2004 | US6740772 Pgd2 agonists; sleep inducing action; intracerebral transition; stability |
| 05/12/2004 | EP1417975A1 REMEDIES FOR DISEASES WITH BONE MASS LOSS HAVING EP sb 4 /sb AGONIST AS THE ACTIVE INGREDIENT |
| 04/20/2004 | US6723748 Vision disorders; topical applying |
| 04/14/2004 | EP1406854A1 Process and intermediates to prepare latanoprost |
| 04/07/2004 | EP1089970B1 Oxidation inhibitors for prostane derivatives |
| 04/07/2004 | CN1144783C Prostaglandin derivative |
| 04/07/2004 | CN1144588C 睡眠诱发剂 Sleep-inducing agent |
| 04/06/2004 | US6716876 Cyclopentane(ENE)heptenoic or heptanoic acids and derivatives thereof useful as therapeutic agents |
| 03/17/2004 | EP1397347A2 Preparation of 17-phenyl- 18, 19, 20- trinor-pgf2a and its derivatives |
| 03/16/2004 | US6706755 For treating ocular hypertension or glaucoma |
| 03/10/2004 | EP1395552A2 Cyclopentane heptan(ene) acyl sulfonamide, 2-alkyl or 2-arylalkyl, or 2-heteroarylalkenyl derivatives as therapeutic agents for the treatment of ocular hypertension |
| 03/04/2004 | US20040044045 Cyclopentane heptan(ene)oic acid, 2-heteroarylalkenyl derivatives as therapeutic agents |
| 02/25/2004 | EP1042283B1 Omega-cycloalkyl-prostaglandin e2 derivatives |
| 02/18/2004 | EP1389198A2 Process for the preparation of prostaglandins and analogues thereof |
| 02/18/2004 | EP1389116A1 Cathartic composition |
| 02/10/2004 | US6689901 Process and intermediates to prepare latanoprost |
| 02/04/2004 | EP1385819A1 Process for preparing prostaglandin derivatives and stereospecific starting material thereof |
| 02/04/2004 | EP1385526A2 3, 7 or 3 and 7 thia or oxa prostanoic acid derivatives as agents for lowering intraocular pressure |
| 01/22/2004 | WO2004007442A1 Prostaglandin derivatives |
| 01/20/2004 | US6680339 15-fluoro prostaglandins as ocular hypotensives |
| 01/08/2004 | WO2003080552A3 Cyclopentenone derivatives, their preparation and use in medecime |
| 11/27/2003 | WO2002100388A3 Cyclopentane heptan (ene) acyl sulfonamide, 2-alkyl or 2-arylalkyl, or 2-heteroarylalkenyl derivatives as therapeutic agents for the treatment of ocular hypertension |
| 11/18/2003 | US6649653 15-fluoro prostaglandins as ocular hypotensives |
| 11/11/2003 | CA2144967C Non-acidic cyclopentane heptanoic acid, 2-cycloalkyl or arylalkyl derivatives as therapeutic agents |
| 10/28/2003 | US6639111 Bind on EP4 subtype receptor selectively and binds on the other subtype receptors weakly; side-effect reduction; autoimmune diseases; asthma; bone disorders; degenerative nerve diseases; sleeping disorders; anticoagulants |
| 10/23/2003 | WO2002096868A3 Preparation of 17-phenyl- 18, 19, 20- trinor-pgf2a and its derivatives |