| Patents for C07C 405 - Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins (3,702) |
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| 05/15/1991 | EP0259468B1 Cyclodextrinclathrates of carbacycline derivatives and their use as medicinal drugs |
| 05/15/1991 | EP0163672B1 20-alkyl-7-oxoprostacycline derivatives and production process thereof |
| 05/07/1991 | US5013758 Hypotensive, anticoagulant, bronchodilator |
| 05/02/1991 | EP0424915A2 Methods for producing prostaglandins and for purifying the same |
| 04/24/1991 | EP0423697A2 Emulsion of lipid containing a prostaglandin analogue |
| 04/23/1991 | CA1283409C2 Process and intermediates for making 16-phenoxy- and 16-substituted phenoxy-prostatrienoic acid derivatives and their stereoisomers |
| 04/23/1991 | CA1283408C2 Processes and intermediates for making 16-phenoxy- and 16-substituted phenoxy-prostatrienoic acid derivatives and their steroisomers |
| 04/20/1991 | WO1991005766A1 2-substituted 2-cyclopentenone and carcinostatic agent and osteogenesis promoter containing the same as active ingredient |
| 04/20/1991 | CA2044179A1 2-substituted-2-cyclopentenone compound and anticancer agent and bone formation accelerator comprising same as active ingredient |
| 04/09/1991 | US5006539 Thromborane inhibitor |
| 04/02/1991 | US5004752 Hypotensive agents, antiulcer, antisecretory agents |
| 03/26/1991 | US5002972 Compound and composition of substituted hexenoic acid derivatives useful for treating thromboxane A2 mediated diseases |
| 03/19/1991 | US5001153 Ocular hypotensive agents |
| 03/13/1991 | EP0416064A1 20-alkyl-13,14,18,18,19,19-hexadehydro-3-oxa-isocarbacycline derivatives and their pharmaceutical use |
| 02/27/1991 | CN1011783B Process for preparation of cyclopentyl ethers |
| 02/19/1991 | US4994584 Reducing number of processes for protecting carboxyl group in the chain and hydroxyl groups on the ring |
| 02/19/1991 | US4994274 Treating glaucoma |
| 02/12/1991 | US4992581 Novel methods of manufacturing thromboxane A2 antagonists |
| 02/12/1991 | CA1280112C Prostaglandin i2 analogue and pharmaceutical containing the same |
| 02/06/1991 | CN1048980A Intraocular pressure reducing 11, 15-diacyl prostaglandins |
| 01/30/1991 | EP0410786A1 Intraocular pressure reducing 11,15-diacyl prostaglandins |
| 01/30/1991 | EP0247202B1 Isocarbacyclin derivatives and process for their preparation |
| 01/28/1991 | CA2020252A1 Intraocular pressure reducing 11, 15-diacyl prostaglandins |
| 01/24/1991 | DE3923797A1 9-fluor-prostaglandin-derivate, verfahren zu ihrer herstellung und ihre pharmazeutische verwendung 9-fluoro-prostaglandin derivatives, to processes for their preparation and their pharmaceutical use |
| 01/17/1991 | DE3923798A1 (delta)(pfeil hoch)8(pfeil hoch)-und(delta)(pfeil hoch)9(pfeil hoch)-prostaglandin-derivate, verfahren zu ihrer herstellung und ihre pharmazeutische verwendung (Delta) (arrow up) 8 (arrow up) -and (delta) (arrow up) 9 (arrow up) -prostaglandin derivatives, process for their production and their pharmaceutical use |
| 01/15/1991 | WO1991001303A1 Δ8 and Δ9-PROSTAGLANDINE DERIVATES, THEIR PROCESS OF PRODUCTION AND THEIR PHARMACEUTICAL USE |
| 01/15/1991 | WO1991001302A1 9-fluor-prostaglandine derivates, their process of production and their pharmaceutical use |
| 01/15/1991 | CA2036386A1 9-fluoroprostaglandin derivatives, process for their production and their pharmaceutical use |
| 01/15/1991 | CA2036383A1 8-and 9-prostaglandin derivatives, process for their production and their pharmaceutical use |
| 01/08/1991 | US4983753 Precursors and synthesis of di-(methyl)-16,16-(dimethyl)-11-alpha,15-alpha beta-dihydroxy-9-oxo-2,13-trans,trans-prostadienoates |
| 01/08/1991 | US4983629 11-haloprostane derivatives, processes for their preparation and their use as medicinal agents |
| 01/08/1991 | US4983627 Novel 6-alkyl and 6.8-dialkylbicyclo(4.2.0)octane derivatives |
| 01/02/1991 | EP0405116A2 Phenylalkan(en)oic acids |
| 01/01/1991 | US4981872 Prostaglandin derivatives, their preparation and their therapeutic use |
| 12/27/1990 | CA1278311C2 Prostaglandins |
| 12/18/1990 | US4978775 Process for producing bicyclo[3.3.0]octanes |
| 12/11/1990 | US4977163 Antiasthmatics; cardiovascular disorders |
| 11/29/1990 | WO1990014329A1 Leukotriene b4 derivatives, process for producing them and their use as drugs |
| 11/29/1990 | CA2033187A1 Leukotriene-b derivatives, process for their production and their use as pharmaceutical agents |
| 11/28/1990 | EP0399839A2 Intraocular pressure reducing 15-acyl prostaglandins |
| 11/28/1990 | EP0399633A1 Leukotriene B4 derivatives, process for their preparation and their use as medicines |
| 11/28/1990 | CN1010587B Method for new salts preparation |
| 11/27/1990 | CA1276931C2 Process and intermediates for making 16-phenoxy- and 16-substituted phenoxy-prostatrienoic acid derivatives and their stereoisomers |
| 11/25/1990 | CA2014038A1 Intraocular pressure reducing 15-acyl prostaglandins |
| 11/20/1990 | US4971987 New carbacycline, process for their production and their use as a drug |
| 11/07/1990 | EP0396024A2 Esters, medicaments containing them and preparation of these esters and medicaments |
| 11/05/1990 | CA2012921A1 Esters, medicaments containing them and process for the preparation of these esters and medicaments |
| 11/01/1990 | WO1990012576A1 Liquid prostaglandin composition |
| 10/23/1990 | CA1275407C 9-halogen prostaglandins, processes for their manufacture and useas pharmaceuticals |
| 10/17/1990 | CN1046163A Interphenylene 7-oxabicycloheptyl substituted heterocyclic amide prostaglandin analogs useful in treatment of thrombotic and vasospastic disease |
| 10/10/1990 | EP0391652A1 Interphenylène 7-oxabicycloheptyl substituted heterocyclic amide prostaglandin analogs useful in the treatment of thrombotic and vasopastic disease |
| 10/09/1990 | CA1275095A1 Carbacyclins, processes for their preparation and their use as pharmaceuticals |
| 10/09/1990 | CA1275094A1 Cyclopentyl ethers and their preparation and pharmaceutical formulation |
| 10/09/1990 | CA1275093A1 Carbacyclins, processes for their manufacture and their use as pharmaceuticals |
| 10/04/1990 | WO1990011276A1 Novel process for producing optically active bicyclo [3.3.0] -octane derivatives |
| 10/04/1990 | WO1990011275A1 20-alkyl-13,14,18,18,19,19-hexadehydro-3-oxa-isocarbacycline derivatives and their pharmaceutical use |
| 09/26/1990 | EP0389162A1 2,5,6,7-Tetranor-4,8-inter-m-phenylene PGI2 derivatives |
| 09/26/1990 | EP0148953B1 7-fluoroprostaglandins and process for their preparation |
| 09/25/1990 | CA1274512A1 Prostaglandins |
| 09/20/1990 | DE3909329A1 20-alkyl-13,14,18,18,19,19-hexadehydro-3- oxa-isocarbacyclin-derivate und ihre pharmazeutische verwendung 20-alkyl-13,14,18,18,19,19-hexadehydro-3-oxa-isocarbacyclin derivatives and their pharmaceutical use |
| 09/20/1990 | DE3909325A1 Neues verfahren zur herstellung von optisch aktiven bicyclo(3.3.0)octan-derivaten New process for production of optically active bicyclo (3.3.0) octane derivatives |
| 09/18/1990 | US4958037 Precursors and synthesis of methyl-9-oxo-11α, 16-dihydroxy-16-vinyl-5-cis-13-trans-prostadienoates |
| 09/12/1990 | EP0386901A1 Novel 5-hetero-6-oxo-PGE derivatives |
| 09/11/1990 | CA1273919A1 Prostaglandin derivatives, their preparation and use |
| 09/04/1990 | US4954524 Hypotensive, anticoagulant, cardiovascular |
| 08/29/1990 | EP0384747A1 Pharmaceutical or veterinary preparations of substituted hexenoic acid derivatives |
| 08/20/1990 | CA2010505A1 5-hetero-6-oxo-pge derivatives |
| 07/31/1990 | US4945106 Prostaglandins |
| 07/26/1990 | WO1990002728A3 6-oxo-9-fluor-prostaglandin derivatives, process for producing them and their use as drugs |
| 07/04/1990 | EP0215949B1 Process for preparing 16-substituted prostaglandin e's |
| 06/28/1990 | WO1990006917A1 Novel thromboxane a2 antagonists |
| 06/20/1990 | EP0373915A1 Novel thromboxane A2 antagonists |
| 06/20/1990 | EP0373612A2 Process for preparing allenic prostanoic acid derivatives |
| 06/19/1990 | US4935446 Prostaglandin analogues, process for their preparation and pharmaceutical compositions containing them |
| 06/13/1990 | CA2005243A1 Process for preparing allenic prostanoic acid derivatives |
| 06/05/1990 | CA1269936A1 Prostaglandins |
| 05/31/1990 | WO1990005720A1 Process for producing carbacyclin derivatives by stereoselective introduction of the 5.6 double bond |
| 05/29/1990 | US4929740 Process for making 16-phenoxy- and 16-(substituted phenoxy)-prostatrienoic acid derivatives |
| 05/23/1990 | EP0369563A1 Process for the preparation of carbacyclin derivatives by stereoselective introduction of the 5,6 double bond |
| 05/23/1990 | EP0369463A2 Conjugate of prostaglandin and polysaccharide |
| 05/18/1990 | CA2002965A1 Conjugate of prostaglandin and polysaccharide |
| 05/16/1990 | EP0208755B1 Thromboxane antagonists in the treatment of hormone-dependent neoplasias |
| 05/15/1990 | US4925956 Novel process for manufacturing optically active carbacyclin intermediates |
| 05/01/1990 | US4921995 Process for producing 16-substituted prostaglandines |
| 04/18/1990 | EP0364417A1 Prostaglandin derivatives for the treatment of glaucoma or ocular hypertension |
| 04/18/1990 | EP0198829B1 9-halogen-prostaglandine derivatives, preparation process and utilization thereof as drugs |
| 04/17/1990 | US4918202 10-substituted-5,9-dioxatricyclo(6.4.0.0(2,6))dodecane-4-one |
| 04/17/1990 | CA1267892A1 Processes and intermediates for making 16-phenoxy- and 16-substituted phenoxy-prostatrienoic acid derivatives and their stereoisomers |
| 04/11/1990 | EP0362686A2 Method for preparing the (+)-isomer of cloprostenol |
| 04/10/1990 | US4916238 Process for preparing allenic prostanoic acid derivatives |
| 04/04/1990 | EP0361772A2 Cyclopentyl ethers and their preparation and pharmaceutical formulation |
| 03/27/1990 | US4912235 Unnatural prostaglandin configuration |
| 03/22/1990 | WO1990002728A2 6-oxo-9-fluor-prostaglandin derivatives, process for producing them and their use as drugs |
| 03/22/1990 | WO1990002553A1 Prostaglandin derivatives for the treatment of glaucoma or ocular hypertension |
| 03/22/1990 | DE3831222A1 6-oxo-9-fluor-prostaglandin-derivate verfahren zu ihrer herstellung und ihre pharmazeutische verwendung 6-oxo-9-fluoro-prostaglandin derivatives processes for their preparation and their pharmaceutical use |
| 03/06/1990 | US4906663 6-fluoroprostaglandins |
| 02/27/1990 | US4904820 Process for substituting a hydrocarbon group |
| 02/20/1990 | US4902717 Prostaglandins |
| 02/07/1990 | EP0353917A1 Precursor of prostaglandin and production thereof |
| 01/16/1990 | US4894473 Process for preparing 7-(2-hexyl-5-hydroxy-cyclopentyl)-heptanoic acid |