Patents for C07C 405 - Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins (3,702) |
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01/16/1990 | US4894336 Cultures, microorganisms, hydrolytic enzymes |
01/10/1990 | EP0349658A1 New prostanoids and their use for increasing the birth rate in animal females |
01/09/1990 | CA1264320A1 Prostaglandin analogues, process for their preparation and pharmaceutical compositions containing them |
12/19/1989 | US4888358 13,14-dihydroprostaglandin C-type derivatives |
12/13/1989 | EP0345951A1 Tracheobronchodilator |
12/12/1989 | US4886903 Process for production of prostaglandins D2 |
12/12/1989 | US4886788 Cyclodextrin clathrates of carbacyclin derivatives and their use as medicinal agents |
12/06/1989 | EP0344235A1 Prostaglandin derivatives for the treatment of glaucoma or ocular hypertension. |
11/28/1989 | CA1263382A1 Carbacyclins, processes for their production and their use as medicinal agents |
11/08/1989 | EP0340247A1 New process for the antipodal separation of bicyclo 3.3.0]octane-3,7-dion-2-carboxylic acid esters and their 7-monocetals. |
10/25/1989 | EP0338796A2 2-Substituted-2-cyclopentenones |
10/18/1989 | EP0173753B1 6-substituted prostaglandin e1's and process for their preparation |
10/11/1989 | EP0336522A2 Thromboxane antagonists for use in the treatment of hormone-dependent neoplasias |
10/04/1989 | EP0335827A1 Process for the preparation of bicyclo(3.3.0)octan-3-one derivatives |
10/03/1989 | US4871869 Intermediate for prostacyclin |
10/03/1989 | US4871772 Process for making a stable pharmaceutical preparation of prostagladin E compounds, and/or 15R forms thereof |
09/26/1989 | US4870104 Antiulcer, luteolytic |
09/26/1989 | CA1261827A1 Tetraenyl prostaglandins |
09/26/1989 | CA1261826A1 13-aza-14-oxo-txa.sub.2 analogues |
09/13/1989 | EP0332178A1 2-cyclopentenone derivatives |
09/13/1989 | EP0215860B1 9-halogenprostaglandines, process for their manufacture |
09/12/1989 | US4866205 5-hydroxy-2-(3-hydroxy-4,4-dimethyl-1-octenyl)-3 -methylcyclopentane acetic acid and derrivatives; cardiovascular agents, oxytocics |
09/05/1989 | US4863961 Tetraenyl prostaglandins |
08/23/1989 | EP0134246B1 Prostacyclines and process for their preparation |
08/02/1989 | EP0325869A1 Novel processes and intermediates |
07/26/1989 | EP0324815A1 New 9-substituted carbocycline derivatives, process for manufacturing them and their use as drugs |
07/25/1989 | US4851523 Cyclopentyl ethers and their preparation and pharmaceutical formulation |
07/18/1989 | US4849535 Production of cyclopentenylheptanoic acid derivatives |
07/12/1989 | EP0323913A2 Processes for the preparation of optically active bicyclo [3.3.0]octane |
07/11/1989 | US4847370 Cyclopentyl ethers and their preparation and pharmaceutical formulation |
07/11/1989 | US4847369 Antiulcer agents; antisecretory agents |
07/11/1989 | US4847293 Tetraenyl prostaglandins |
07/04/1989 | US4845282 Process for prostaglandin E1 production, and novel delta 7-prostaglandins E and 7-hydroxyprostaglandins E |
06/20/1989 | US4841091 Process for producing 16-substituted prostaglandin es. |
06/20/1989 | US4840968 Reacting prostaglandin hydophobic ester with ethyldiisopropylamine |
06/20/1989 | CA1256029A1 Process for making a stable pharmaceutical preparation of prostaglandin e compounds, and/or 15r thereof |
06/13/1989 | US4839388 Prostacyclins and pharmaceuticals containing the same |
06/06/1989 | US4837363 Gastric acid secretion inhibitors, antiulcer agents |
06/06/1989 | US4837342 Stability |
06/06/1989 | US4837234 Prostaglandins |
06/06/1989 | CA1255298A1 Prostaglandin analogues |
05/23/1989 | US4833271 Structurally defined oligomers and preparation thereof for the protection of oxidative phosphorylation and which exhibit ionophoretic activity |
05/23/1989 | US4833157 Antiulcer agents |
05/02/1989 | US4827017 Novel carbacyclins, processes for their production and their use as medicinal agents |
05/02/1989 | CA1253494A1 12,16 - DIFLUOROPROSTAGLANDIN F.SUB.2.alpha. COMPOUNDS |
05/02/1989 | CA1253493A1 Bicycloheptane substituted ethers |
04/26/1989 | EP0312906A2 Novel sulfonamide derivatives |
04/26/1989 | EP0173754B1 7-thiaprostaglandin e 1?'s and process for their preparation |
04/25/1989 | US4824993 Cyclopentyl ethers and their preparation and pharmaceutical formulation |
04/20/1989 | WO1989003384A1 Prostaglandin derivatives for the treatment of glaucoma or ocular hypertension |
04/19/1989 | EP0312055A2 6-Fluoroprostaglandins |
04/18/1989 | US4822909 Using aminosulfur trifluoride florinating agent |
04/18/1989 | US4822804 5,6,7,-trinor-4,8-inter-m-phenylene 2-nor PGI2 derivatives and anti-ulcer, anti-thrombotic and anti-hypertensive pharmaceutical compositions containing them |
04/18/1989 | CA1252781A1 Allenic prostacyclins |
04/18/1989 | CA1252780A1 Carbacyclin derivatives, process for their preparation and compositions containing them |
04/11/1989 | US4820728 Tetraenyl prostaglandins |
04/11/1989 | CA1252461A1 Bicyclooctane derivatives and their production and use |
04/05/1989 | EP0310409A2 Prostaglandin derivatives |
03/28/1989 | US4816472 Antisecretory agents |
03/28/1989 | CA1251788A1 Sulfur-containing 6-ketoprostaglandins |
03/22/1989 | EP0308135A2 Ocular hypotensive agents |
03/21/1989 | US4814490 Bicyclic olefin with alkyl acetoxymercurio carboxylate |
03/14/1989 | US4812475 New method of treatment using prostaglandin analogues |
03/14/1989 | US4812457 Prostaglandin derivatives |
03/14/1989 | CA1251202A1 Carbacylin derivatives |
03/14/1989 | CA1251201A1 9-halogen prostaglandins |
03/14/1989 | CA1251200A1 Carbacyclins, processes for their manufacture and their use as medicaments |
03/07/1989 | US4810805 Intermediates for prostac6yclins |
03/07/1989 | CA1250835A1 .alpha. CHAIN DIENIC PROSTANOIC ACID DERIVATIVES |
03/07/1989 | CA1250834A1 5-fluoro-carbacyclins, process for their manufacture and their use as medicaments |
02/23/1989 | WO1989001470A1 Process for producing e/z mixtures of 2-(bicyclo[3.3.0]octane-3-ylidene) acetic acid derivatives with predominant e or z moieties |
02/21/1989 | US4806668 Producing 5-chloro-3-hydroxycyclopentyl aldehydes |
02/21/1989 | CA1250285A1 Intermediates for the preparation of prostaglandin analogues |
02/15/1989 | EP0303562A1 Process for the preparation of E/Z mixtures of 2-(bicyclo[3.3.0]octan-3-ylidene) acetic-acid derivatives with a major proportion of E or Z isomer |
02/14/1989 | US4804787 Processes and intermediates for making 16-phenoxy and 16-substituted phenoxy-prostatrienoic acid derivatives |
02/09/1989 | WO1989000990A1 New 9-substituted carbocycline derivatives, process for manufacturing them and their use as drugs |
02/08/1989 | EP0181409B1 15(r+s)-fluorine-11,15-didesoxyprostaglandin e 1? derivatives |
02/07/1989 | CA1249842A1 Method for preparing ( )s-2-hydroxy-2-methyl-hexanoic acid |
01/26/1989 | WO1989000559A1 9-halogen-(z)-prostaglandin derivatives, process for manufacturing them, and their use as drugs |
01/26/1989 | DE3724190A1 9-Halo-3-oxa-(Z)- DELTA <5>-prostaglandin derivatives, process for their preparation, and their use as medicaments |
01/26/1989 | DE3724189A1 9-Halo-(Z)- DELTA <4>-prostaglandin derivatives, process for their preparation and their use as medicaments |
01/18/1989 | EP0299914A1 9-Halogen (Z) prostaglandin derivatives, process for their production and their use as medicines |
01/11/1989 | EP0157883B1 Process for preparing prostaglandin d 2?'s |
01/10/1989 | US4797506 Antiulcer agents |
01/10/1989 | CA1248527A1 Cyclopentyl ethers and their preparation and pharmaceutical formulation |
01/10/1989 | CA1248526A1 [3.2.0]bicycloheptanone oxime ethers with valuable therapeutic properties |
01/10/1989 | CA1248525A1 Carbacyclins, process for their manufacture and their use as medicaments |
12/29/1988 | WO1988010252A1 Prostaglandin derivates, their process and pharmaceutical compositions |
12/21/1988 | EP0295284A1 Compositions containing sulphur prostaglandines |
12/20/1988 | US4792617 Lower intraocular pressure |
12/20/1988 | US4792550 Thromboxane antagonist-hypotensive agent; cardiovascular, nervous system disorders; antiallergens |
12/14/1988 | EP0294757A2 Process of preparing higher order cuprate complexes |
12/13/1988 | CA1246594A1 Prostaglandins |
12/13/1988 | CA1246561A1 Prostaglandin derivatives |
12/13/1988 | CA1246560A1 Intermediates for making 16-phenoxy and 16- substituted phenoxy-prostatrienoic acid derivatives |
12/13/1988 | CA1246558A1 Carbacyclin amides, process for their manufacture and their use as medicaments |
12/13/1988 | CA1246557A1 Carbacyclin esters, process for their manufacture and their use as medicaments |
12/06/1988 | US4789685 9-fluoroprostaglandin derivatives, their preparation and use as medicinal agents |
11/29/1988 | US4788319 Prostaglandin intermediates |
11/29/1988 | CA1245646A1 Carbacyclins, process for their manufacture and their use as medicaments |