Patents
Sitemap › C07 - Organic chemistry › C07C - Acyclic or carbocyclic compounds › C07C 405 - Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins
Patents for C07C 405 - Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins (3,702)
07/1999
07/01/1999WO1999032441A1 13-oxa prostaglandins for the treatment of glaucoma and ocular hypertension
05/1999
05/27/1999WO1999025358A1 Cyclopentane heptan(ene)oic acid, 2-heteroarylalkenyl derivatives as therapeutic agents
05/27/1999CA2310630A1 Cyclopentane heptan(ene)oic acid, 2-heteroarylalkenyl derivatives as therapeutic agents
05/25/1999US5906989 Cyclopentane(ENE) heptenoic or heptanoic acids and derivatives thereof useful as therapeutic agents
05/06/1999WO1999021830A1 Process for stereoselective synthesis of prostacyclin derivatives
05/06/1999EP0912507A1 Cyclopentan(en)oic acid, 2-alkenyl derivatives as therapeutic agents in the treatment of ocular hypertension
05/06/1999CA2847985A1 Process for stereoselective synthesis of prostacyclin derivatives
05/06/1999CA2307163A1 Process for stereoselective synthesis of prostacyclin derivatives
04/1999
04/28/1999EP0737184B1 Cyclopentane(ene) heptenoic or heptanoic acids and derivatives thereof useful as therapeutic agents
04/13/1999CA2099667C Agent for treating hepatic diseases
04/06/1999US5892099 Autoimmune disease, bone disorders, liver damage, cardiovascular disorders
04/06/1999US5891910 Cytoprotective drugs
03/1999
03/30/1999US5889052 Use of cloprostenol and fluprostenol analogues to treat glaucoma and ocular hypertension
03/30/1999CA2144313C 4-hydroxy-2-cyclopentenone derivative and carcinostatic and osteogenesis promoter containing the same
03/23/1999US5886035 Difluoroprostaglandin derivatives and their use
03/23/1999US5886034 Antiulcer agents
03/18/1999WO1999012899A1 A process for making prostaglandin f analogs
03/18/1999WO1999012898A1 Aromatic c16-c20-substituted tetrahydro prostaglandins useful as fp agonists
03/18/1999WO1999012897A1 A process for making epoxide intermediates
03/18/1999WO1999012896A1 Aromatic c16-c20-substituted tetrahydro prostaglandins useful as fp agonists
03/18/1999WO1999012895A1 Aromatic c16-c20-substituted tetrahydro prostaglandins useful as fp agonists
03/18/1999WO1998058911A3 Prostaglandin agonists
03/18/1999CA2303797A1 A process for making epoxide intermediates
02/1999
02/25/1999WO1998052915A3 Leukotriene b4 derivatives, in particular oximo-ltb4 antagonists
02/25/1999WO1998052912A3 Leukotriene b4 antagonists, in particular 3-carba-tetrahydronaphthalene-ltb4 antagonists
02/23/1999US5874634 Substituted cyclopentene derivatives and method for preparing the same
02/02/1999US5866602 Keto-substituted tetrahydrofuran analogs of prostaglandins as ocular hypotensives
12/1998
12/30/1998WO1998058911A2 Prostaglandin agonists
12/30/1998WO1998058910A1 Prostaglandin pharmaceutical compositions
12/24/1998DE19722846A1 Leukotrien-B¶4¶-Derivate, insbesondere 7-Methylcyclohexyl-LTB¶4¶-Antagonisten Leukotriene B¶4¶ derivatives, in particular 7-methylcyclohexyl-LTB¶4¶ antagonists
12/23/1998WO1998057930A1 Keto-substituted tetrahydrofuran analogs of prostaglandins as ocular hypotensives
12/15/1998US5849791 Prostaglandin derivatives for the treatment of glaucoma or ocular hypertension
12/10/1998DE19722853A1 Leukotrien-B¶4¶-Antagonisten, insbesondere 3-Carba-Tetrahydronaphthalin-LTB¶4¶-Antagonisten B¶4¶ leukotriene antagonists, in particular 3-carba-tetrahydronaphthalene-LTB¶4¶ antagonists
12/10/1998DE19722845A1 Leukotrien-B¶4¶-Derivate, insbesondere Interphenylen-7-Methylcyclohexyl-LTB¶4¶-Antagonisten Leukotriene B¶4¶ derivatives, in particular interphenylene 7-methylcyclohexyl-LTB¶4¶ antagonists
12/08/1998CA2030345C Use of 15-keto-prostaglandin compound for improvement of encephalic function
11/1998
11/26/1998WO1998052916A1 Novel leukotriene-b derivatives, method for the production and use thereof
11/26/1998WO1998052915A2 Leukotriene b4 derivatives, in particular oximo-ltb4 antagonists
11/26/1998WO1998052914A1 Leukotriene b4 derivatives, in particular 7-methylcyclohexyl-ltb4 antagonists
11/26/1998WO1998052912A2 Leukotriene b4 antagonists, in particular 3-carba-tetrahydronaphthalene-ltb4 antagonists
11/26/1998DE19722848A1 Leukotrien-B¶4¶-Derivate, insbesondere Oximo-LTB¶4¶-Antagonisten Leukotriene B¶4¶ derivatives, in particular oximo-LTB¶4¶ antagonists
11/26/1998CA2291123A1 Leukotriene b4 derivatives, in particular oximo-ltb4 antagonists
11/26/1998CA2291112A1 Leukotriene b4 derivatives, in particular 7-methylcyclohexyl-ltb4 antagonists
11/05/1998WO1998039293A3 13-thia prostaglandins for use in glaucoma therapy
11/04/1998EP0874816A1 Process for the preparation of prostaglandin e1
10/1998
10/28/1998EP0716648B1 New 9-chloro-prostaglandin derivatives
10/06/1998US5817694 Oxytocics
09/1998
09/30/1998CN1194266A Omega-naphthenic base prostaglandin E2 derivatives
09/29/1998CA2176763C Misoprostol
09/15/1998US5807892 Use of certain prostaglandin analogues to treat glaucoma and ocular hypertension
09/11/1998WO1998039293A2 13-thia prostaglandins for use in glaucoma therapy
09/11/1998CA2276666A1 13-thia prostaglandins for use in glaucoma therapy
08/1998
08/26/1998EP0860430A2 Omega-cycloalkyl-prostaglandin E2 derivatives
08/25/1998US5798378 Treatment of ocular hypertension
08/20/1998WO1998020880A3 11-Halo prostaglandins for the treatment of glaucoma or ocular hypertension
08/18/1998US5795914 Phenylalkan(en)oic acid
08/13/1998WO1998034916A1 11,15-o-dialkylprostaglandin e derivatives, process for producing the same, and drugs containing the same as the active ingredient
08/04/1998CA2228828A1 Omega-cycloalkyl-prostaglandin e2 derivatives
07/1998
07/29/1998EP0855389A2 A 3,7-dithiaprostanoic acid derivative
07/21/1998US5783602 Leukotriene-B4 derivatives, process for their production and their use as pharmaceutical agents
07/16/1998WO1998021181A3 15-fluoro prostaglandins as ocular hypotensives
07/15/1998CN1187486A Difluoroprostaglundin Derivatives and their use
07/01/1998EP0850926A2 Difluoroprostaglandin derivatives and their use
06/1998
06/30/1998US5773654 7-(5-substituted cyclopentyl) and (5-substituted cyclopentenyl) heptyl alcohols, heptylamines and heptanoic acid amides, and method of lowering intraocular pressure in the eye of a mammal by administration of these compounds
06/25/1998WO1998021182A3 Use of cis-δ4 analogs of prostaglandins as ocular hypotensives
06/23/1998US5770759 13,14-dihydro-15-keto-pgf's; vasopressors
06/17/1998EP0847276A2 Method for effecting vasodilation with (1,5-inter)aryl prostaglandin derivatives
05/1998
05/27/1998EP0656889B1 9-chloroprostaglandin esters and amides and their use in the preparation of drugs
05/26/1998US5756818 Hydrogenation; protecting; deprotecting; clathrates
05/22/1998WO1998021182A2 Use of cis-δ4 analogs of prostaglandins as ocular hypotensives
05/22/1998WO1998021181A2 15-fluoro prostaglandins as ocular hypotensives
05/22/1998WO1998021180A1 Conformationally rigid aryl- or heteroaryl prostaglandins for use in glaucoma therapy
05/22/1998WO1998021179A1 Process for the preparation of prostaglandins
05/22/1998WO1998020880A2 11-halo prostaglandins for the treatment of glaucoma or ocular hypertension
05/22/1998CA2271035A1 Process for the preparation of prostaglandins
05/22/1998CA2269855A1 15-fluoro prostaglandins as ocular hypotensives
05/22/1998CA2269853A1 Use of cis-.delta.4 analogs of prostaglandins as ocular hypotensives
05/20/1998CN1182136A Production technology of material medicine for prostaglandin E1
05/13/1998EP0627416B1 Process for producing prostaglandin e
05/12/1998US5750784 Method for effecting vasodilation with (1,5-inter) aryl prostaglandin derivatives
04/1998
04/22/1998EP0741686B1 New leukotriene b4 derivatives, methods of preparing them and their use as drugs
04/14/1998US5739161 Prostaglandins; diarrhea side effect reduction
04/08/1998EP0562006B1 Homo-prostaglandin derivatives as ocular hypotensives
04/07/1998CA2003260C Process for the production of carbacyclin derivatives by stereoselective introduction of the 5,6 double bond
04/01/1998CN1177956A Process for preparing prostaglandin E1, E2 and analogs thereof using furylcopper reagents
03/1998
03/26/1998WO1998012175A1 Fluorinated prostaglandin derivatives and medicines
03/24/1998US5731452 7-thiaprostaglandins and method of production thereof
03/04/1998EP0825980A1 Cyclopentane heptan(ene)oic acid, 2-heteroarylakenyl derivatives as therapeutic agents for the treatment of ocular hypertension
02/1998
02/24/1998US5721273 Use of certain 9-halo-13,14-dihydroprostaglandins to treat glaucoma and ocular hypertension
02/10/1998US5716989 Bicyclo 3.3.0!octane derivatives, process for their production and their pharmaceutical use
01/1998
01/27/1998CA2037009C 15-dehydroxy-16-oxoprostaglandins
01/07/1998EP0815076A1 Process for preparing prostaglandin e1, e2 and analogs thereof using furylcopper reagents
12/1997
12/16/1997US5698733 Use of 9-deoxy prostaglandin derivatives to treat glaucoma
12/16/1997US5698590 Treatment of peripheral circulatory disorders and ulcers and for blood flow maintenance after surgery
12/04/1997WO1997045405A1 Cyclopentan(en)oic acid, 2-alkenyl derivatives as therapeutic agents in the treatment of ocular hypertension
12/04/1997CA2256404A1 Cyclopentan(en)oic acid, 2-alkenyl derivatives as therapeutic agents in the treatment of ocular hypertension
11/1997
11/25/1997US5690957 Prostaglandin derivatives
11/19/1997EP0807634A2 Misoprostol, process for its preparation using an organometallic cuprate complex
11/18/1997US5688819 Cyclopentane heptanoic acid, 2-cycloalkyl or arylalkyl derivatives as therapeutic agents
11/04/1997US5684177 Preparing an organometallic cuprate complex carrying an organic unsaturated ligand
10/1997
10/29/1997CN1163568A Use of 9-deoxy prostaglandin derivatives to treat glaucoma
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