| Patents for C07C 405 - Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins (3,702) |
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| 11/23/1988 | EP0119949B1 Carbacyclins, process for their manufacture and their use as pharmaceutical compounds |
| 11/17/1988 | EP0290919A1 Optically active octynols and their application in the production of prostaglandins |
| 11/17/1988 | EP0290675A1 Allenic prostacyclins |
| 11/08/1988 | US4783480 6-keto-prostaglandin E1 derivatives |
| 11/02/1988 | EP0289349A1 Prostaglandins of the F series |
| 10/25/1988 | US4780568 Isobutyric acid and other impurities |
| 10/25/1988 | US4780562 Processes and intermediates for making 16-phenoxy and 16-substituted phenoxy-prostatrienoic acid derivatives and their stereoisomers |
| 10/18/1988 | US4778904 Intermediates for making 16-phenoxy- and 16-(substituted phenoxy)-prostatrienoic acid derivatives |
| 10/18/1988 | CA1243313A2 Prostaglandins |
| 10/18/1988 | CA1243312A1 Prostaglandins |
| 10/11/1988 | US4777275 Chemical intermediate for prostaglandine |
| 10/11/1988 | US4777271 Isocarbacyclin derivatives and process for production thereof |
| 10/11/1988 | US4777184 Prostaglandin derivatives, their preparation and use |
| 09/28/1988 | EP0284547A1 6-Oxo prostaglandin-E derivatives, their preparation and pharmaceuticals containing them |
| 09/28/1988 | EP0284180A1 Prostaglandins E and anti ulcers containing same |
| 09/28/1988 | CN88101278A Process for optical resolution bicyclo (3,3,0)-octa-3,7-dione-2-carboxylic ester and 7-ketal |
| 09/27/1988 | US4774341 Bicyclo(3.3.0)octane derivative and preparation thereof |
| 09/22/1988 | WO1988007050A1 New process for the antipodal separation of bicyclo[3.3.0]octane-3,7-dion-2-carboxylic acid esters and their 7-monocetals |
| 09/22/1988 | WO1988007037A1 6-oxoprostaglandin-e derivatives, process for their production and their pharmaceutical application |
| 09/07/1988 | EP0281239A2 Prostaglandins of the D series, and tranquilizers and soporifics containing the same |
| 08/30/1988 | CA1241324A1 Interphenylene carbacyclin derivatives |
| 08/23/1988 | US4766147 Antitumor agents |
| 08/16/1988 | US4764528 Anticoagulants |
| 08/09/1988 | US4762936 Anticoagulant, prostaglandin intermediate |
| 08/09/1988 | US4762935 Precursors and synthesis of methyl-9-oxo-11α,16-dihydroxy-16-vinyl-5-cis-13-trans-prostadienoates |
| 07/27/1988 | EP0276124A2 Prostaglandin derivatives, their preparation and their therapeutic use |
| 07/27/1988 | EP0107693B1 2,3,4-trinor-1,5-inter-m-phenylene-prostacyclin-i2 analogues, process for the preparation thereof and pharmaceutical compositions containing the same |
| 07/14/1988 | WO1988005042A1 Compositions containing sulphur prostaglandines |
| 07/12/1988 | US4757087 Antiulcer agents |
| 07/06/1988 | EP0273216A2 Prostacyclin analogue and anti-ulcer composition containing it as active ingredient |
| 07/05/1988 | US4755531 Thiol esters of 4,5-allenyl prostaglandins and use thereof as antigastric secretion agents |
| 06/28/1988 | US4754059 Omega cycloalkyl prostaglandins |
| 06/28/1988 | US4754055 Allenic prostacyclins |
| 06/22/1988 | EP0272201A1 Stereospecific ketoreduction of bicyclooctanedione-carboxylic-acid esters by microorganisms |
| 06/15/1988 | EP0271433A1 Racemate cleavage of 7-alpha-acyloxy-6-beta-hydroxy-methyl-2-oxabicyclo[3.3.0]octan-3-ones by stereospecific enzymatic acylate hydrolysis |
| 06/15/1988 | EP0271432A2 Racemate cleavage of 3-acyloxy-bicyclo[3.3.0]octan-7-on-2-carboxylic-acid esters by stereospecific enzymatic or microbiological acylate hydrolysis |
| 06/08/1988 | EP0270481A1 Process for the preparation of optically active carbacyclin intermediates |
| 06/07/1988 | CA1237718A1 Ester and amide derivatives of 13,14-didehydro- prostaglandins |
| 05/25/1988 | EP0268548A2 Reduction of ketonic carbacyclin intermediates |
| 05/25/1988 | EP0268389A2 Cyclopenthyl ethers and their preparation and pharmaceutical formulation |
| 05/24/1988 | CA1237127A1 9-substituted carbacyclin analogs |
| 05/19/1988 | WO1988003570A1 RACEMIC SEPARATION OF 7alpha-ACYLOXY-6beta-HYDROXYMETHYL-2-OXABICYCLO[3.3.0]OCTANE-3-ONES BY STEREO-SPECIFIC ENZYMATIC ACYLATE HYDROLYSIS |
| 05/19/1988 | WO1988003568A1 Stereospecific keto-reduction of bicyclooctandione-carboxylic acid esters by microorganisms |
| 05/19/1988 | WO1988003567A1 Racemic dissociation of 3-acyloxilic-bicyclo[3.3.0]octane-7-one-2-carboxylic acid esters by stereospecific enzyme or microbiolog ical acylate hydrolysis |
| 05/19/1988 | WO1988003527A1 Improved keto-reduction of carbacycline intermediates |
| 05/19/1988 | WO1988003526A1 New process for manufacturing optically active carbocycline intermediates |
| 05/11/1988 | EP0266533A2 Precursors and synthesis of methyl-9-oxo-11 alpha, 16-di-hydroxy-16-vinyl-5-cis-13-transprostadienoates |
| 05/03/1988 | US4742080 Therapeutic method for producing bronchodilation by administration of 15-deoxy-16-hydroxy prostaglandin esters |
| 04/27/1988 | EP0265248A2 Cyclopentyl ethers and their preparation and pharmaceutical formulation |
| 04/27/1988 | EP0265247A1 Cyclopentyl ethers and their preparation and pharmaceutical formulation |
| 04/27/1988 | EP0098794B1 Carbacyclines, process for their preparation and their use as medicines |
| 04/26/1988 | US4740523 Interfuranylene prostacyclins |
| 04/12/1988 | US4737590 Prostaglandin intermediates |
| 04/05/1988 | US4736058 Anticoagulants, vasodilators |
| 04/05/1988 | US4735965 Crystalline amine salt; water solubility; materials handling |
| 04/05/1988 | CA1234811A1 Aminocyclopentanes and their preparation and pharmaceutical formulation |
| 03/29/1988 | US4734424 Bicycloheptane substituted diamide and its congener prostaglandin analogs |
| 03/23/1988 | EP0260719A1 Stable prostaglandin-containing composition |
| 03/22/1988 | US4733011 New intermediates for the preparation of 13-thiaprostaglandin derivatives |
| 03/22/1988 | US4732914 Prostacyclin analogs |
| 03/16/1988 | EP0259468A1 Cyclodextrinclathrates of carbacycline derivatives and their use as medicinal drugs. |
| 03/08/1988 | US4730078 Allenic prostacyclins |
| 03/08/1988 | US4730065 Bronchodilators, hypotensives, antisecretory |
| 03/08/1988 | US4730060 Carbacyclin derivatives, method of manufacturing the same and therapeutic agents containing these compounds |
| 01/26/1988 | US4721729 Novel carbacyclins, process for the preparation thereof, and their use as medicinal agents |
| 12/15/1987 | US4713477 Antisecretory agents |
| 12/08/1987 | US4711895 4-hydroxy-2-cyclopentenone, process for production thereof, pharmaceutical composition comprising it |
| 12/03/1987 | WO1987004427A3 Prostaglandin synthesis |
| 12/02/1987 | EP0247740A2 Novel isocarbacyclins and processes for production thereof |
| 12/02/1987 | EP0247202A1 Isocarbacyclin derivatives and process for their preparation |
| 11/24/1987 | US4708963 Novel carbacyclins, their preparation and use |
| 11/17/1987 | US4707555 Prostaglandin intermediates |
| 11/10/1987 | US4705806 Anticoagulants |
| 10/27/1987 | CA1228587A1 9-hydroxy substituted carbacyclin derivatives and related compounds |
| 10/22/1987 | WO1987004428A3 Prostaglandins |
| 10/14/1987 | EP0241328A1 2,4-Pentadienoic acid derivatives and platelet aggregation inhibitors containing the same |
| 10/13/1987 | US4699996 12,16-Difluoroprostaglandin F2 α compounds |
| 10/13/1987 | US4699989 7-fluoroprostaglandins and process for their production |
| 10/13/1987 | US4699921 Circulation ameliorating and antiulcer effect |
| 10/13/1987 | US4699920 9-halo-2-prostaglandin derivatives, processes for the preparation thereof and use thereof as medicinal agents |
| 10/06/1987 | US4698363 Prostacyclin analogues |
| 09/22/1987 | US4695647 Aromatic derivatives of 13-azaprostanoic acid |
| 09/16/1987 | EP0236510A1 Prostacyclins and drugs containing the same |
| 09/11/1987 | WO1987005294A1 Cyclodextrinclathrates of carbacycline derivatives and their use as medicinal drugs |
| 09/08/1987 | US4692464 Novel prostacyclin derivatives and a process for the preparation thereof |
| 09/02/1987 | EP0234576A1 Prostacyclin analogue, and blood circulation improving agent and anti-ulcer composition containing it as active ingredient |
| 09/02/1987 | EP0234158A1 (2-Chloro-3-oxo-1-alkenyl)bicyclo (3.3.0.) octene derivative and process for preparing the same |
| 08/25/1987 | US4689426 5-alkylidene-2-halo-4-substituted-2-cyclopentenone and process for production thereof |
| 08/12/1987 | EP0232126A2 6-Keto-prostaglandin E1 derivatives |
| 08/05/1987 | EP0231078A2 Prostaglandins |
| 07/30/1987 | WO1987004428A2 Prostaglandins |
| 07/30/1987 | WO1987004427A2 Prostaglandin synthesis |
| 07/29/1987 | EP0230381A2 Prostaglandin synthesis |
| 07/28/1987 | US4683330 Interphenylene carbacyclin derivatives |
| 07/28/1987 | US4683328 Tetraenyl prostaglandins |
| 07/21/1987 | US4681962 Novel 7-fluoro-dihydro PGI compounds |
| 07/21/1987 | US4681951 Prostaglandin intermediates |
| 07/14/1987 | US4680415 Intermediates for 7-fluoro dihydro PGI compounds |
| 07/14/1987 | US4680307 Carbacyclin analogs |
| 07/14/1987 | US4680288 Sulfur-containing 6-ketoprostaglandins |