Patents for C07C 405 - Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins (3,702) |
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04/04/2001 | EP1088816A2 Use of certain prostaglandin analogues to treat glaucoma and ocular hypertension |
04/03/2001 | US6211233 Prostaglandin pharmaceutical compositions |
03/22/2001 | WO2001019790A1 Prostaglandin derivatives |
03/22/2001 | WO2001019789A1 Prostaglandin derivatives |
03/22/2001 | CA2384715A1 Prostaglandin derivatives |
03/21/2001 | EP1085012A1 Process for producing purified prostaglandin derivative |
03/20/2001 | US6204287 Treating vision defects |
03/15/2001 | WO2001017957A1 Prostaglandin e analogues |
03/15/2001 | CA2384148A1 Prostaglandin e analogues |
03/14/2001 | EP1083168A1 Prostaglandin derivative |
03/14/2001 | EP1082961A1 Sleep inducing agent |
03/14/2001 | EP1082299A1 C11 oxymyl and hydroxylamino prostaglandins useful as medicaments |
03/08/2001 | WO2000061588A8 Novel intermediate for the synthesis of prostaglandins |
03/07/2001 | EP0847276B1 Method for effecting vasodilation with (1,5-inter)aryl prostaglandin derivatives |
02/27/2001 | CA2012267C Interphenylene 7-oxabicycloheptyl substituted heterocyclic amide prostaglandin analogs useful in the treatment of thrombotic and vasospastic disease |
02/22/2001 | WO2001012596A1 Prostaglandin derivatives |
02/22/2001 | CA2382265A1 Prostaglandin derivatives |
02/20/2001 | US6191291 Oxidation of a substituted cyclopentadiene derivative with an oxidizing agent to form oxirane ring containing substituted cyclopentadiene derivative |
02/14/2001 | EP1075464A1 Novel process |
02/13/2001 | US6187813 Prostaglandin derivatives for the treatment of glaucoma or ocular hypertension |
02/07/2001 | CN1283184A Process for stereo selective synthesis of prostacyclin derivatives |
02/06/2001 | US6184250 Use of cloprostenol and fluprostenol analogues to treat glaucoma and ocular hypertension |
01/10/2001 | EP1066254A1 C11 oxymyl and hydroxylamino prostaglandins useful as fp agonists |
01/09/2001 | US6172109 Side effect reduction; administering topically |
01/02/2001 | US6169111 Conformationally rigid aryl prostaglandins for use in glaucoma therapy |
12/12/2000 | US6160129 Cyclopentane heptan(ene)oic acid, 2-heteroarylalkenyl derivatives as therapeutic agents |
12/12/2000 | US6160013 14-aza prostaglandins for the treatment of glaucoma and ocular hypertension |
12/12/2000 | US6160012 Leukotriene B4 derivatives, in particular oximo-LTB4 - antagonists |
11/22/2000 | CN1058706C Prostaglandin derivative |
10/19/2000 | WO2000061777A1 Process for the preparation of prostaglandin precursors |
10/19/2000 | WO2000061588A1 Novel intermediate for the synthesis of prostaglandins |
10/19/2000 | WO2000061550A1 Prostaglandin e1 derivatives |
10/19/2000 | CA2369662A1 Prostaglandin e1 derivatives |
10/11/2000 | EP1042283A1 $g(v)-CYCLOALKYL-PROSTAGLANDIN E 2? DERIVATIVES |
10/11/2000 | CN1269786A Aromatic C16-C20 substituted tetrahydro prostaglandins useful as EP agonists |
10/11/2000 | CN1269785A Aromatic C16-C20 substituted tetrahydro prostaglandius useful as EP agonists |
10/11/2000 | CN1269784A Aromatic C16-C20 substituted tetrahydro prostagladins useful as FP agonists |
10/11/2000 | CN1269783A Process for making epoxide intermediates |
10/05/2000 | WO2000057701A1 Prostaglandin compounds, compositions and methods of treating peripheral vascular disease and pulmonary hypertension |
10/05/2000 | CA2359652A1 Novel prostaglandin compounds and derivatives thereof, compositions containing the same and method of using the same for the treatment of peripheral vascular disease and pulmonaryhypertension |
09/27/2000 | EP0778269B1 Prostaglandins and process for producing the same |
09/26/2000 | US6124344 Cyclopentane heptan(ene)oic acid, 2-heteroarylalkenyl derivatives as therapeutic agents |
09/08/2000 | WO2000051980A1 C16 unsaturated fp-selective prostaglandins analogs |
09/08/2000 | WO2000051979A1 C16 unsaturated fp-selective prostaglandins analogs |
09/08/2000 | WO2000051978A1 Nitrosated and nitrosylated prostaglandins, compositions and metods of use |
09/08/2000 | WO2000051977A1 Aldehyde intermediates for the preparation of prostaglandin derivatives |
09/06/2000 | EP1032395A1 Cyclopentane heptan(ene)oic acid, 2-heteroarylalkenyl derivatives as therapeutic agents |
08/29/2000 | US6110969 Useful for prevention and/or treatment of autoimmune disease, organ transplantation, asthma, abnormal bone formation, neuron cell death, liver damage, abortion, premature birth or retina neuropathy of glaucoma |
08/29/2000 | CA2012081C 2,5,6,7-tetranor-4,8-inter-m-phenylene pgi 2 derivatives |
08/22/2000 | US6107338 Aromatic C16 -C20 -substituted tetrahydro prostaglandins useful as FP agonists |
08/09/2000 | EP1025083A1 Process for stereoselective synthesis of prostacyclin derivatives |
08/01/2000 | CA2019335C Phenylalkan (en)oic acids |
07/26/2000 | EP1021402A1 Aromatic c16-c20-substituted tetrahydro prostaglandins useful as fp agonists |
07/19/2000 | CN1260778A Prostaglandin pharmaceutical compositions |
06/28/2000 | EP1012138A1 A process for making epoxide intermediates |
06/28/2000 | EP1012137A1 Aromatic c 16?-c 20?-substituted tetrahydro prostaglandins useful as fp agonists |
06/28/2000 | EP1012136A1 Aromatic c 16?-c 20?-substituted tetrahydro prostaglandins useful as fp agonists |
06/14/2000 | EP1008588A1 11,15-o-dialkylprostaglandin e derivatives, process for producing the same, and drugs containing the same as the active ingredient |
05/30/2000 | US6069269 Process for the preparation of prostaglandin E1 |
05/23/2000 | US6066751 Intermediate can be coupled with oxygen, carbon, sulfur, and nitrogen nucleophiles, in the presence of a base or a lewis acid, in a ring-opening process to provide 13,14-dihydro prostaglandin a, e, and f derivatives |
04/13/2000 | WO2000020386A1 Stannane synthesis of prostanoids |
04/11/2000 | US6048895 Antagonists of prostaglandin f for treating bone fractures and diseases and glaucoma |
04/05/2000 | EP0989972A1 Prostaglandin pharmaceutical compositions |
03/30/2000 | WO1999067212A3 Active carbon filter as an oxidation inhibitor for prostane derivatives |
03/28/2000 | US6043275 3,7-dithiaprostanoic acid derivative |
03/23/2000 | WO2000015608A1 φ-SUBSTITUTED PHENYL-PROSTAGLANDIN E DERIVATIVES AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT |
03/15/2000 | EP0985663A1 A 3.7-dithiaprostanoic acid derivative |
03/14/2000 | US6037364 Cyclopentane heptan(ene)oic acid, 2-heteroarylalkenyl derivatives as therapeutic agents |
03/08/2000 | EP0983235A2 Leukotriene b 4? derivatives, in particular oximo-ltb 4? antagonists |
03/08/2000 | EP0983234A1 Leukotriene b 4? derivatives, in particular 7-methylcyclohexyl-ltb 4? antagonists |
02/29/2000 | US6030999 Prostaglandin derivatives for the treatment of glaucoma or ocular hypertension |
02/15/2000 | US6025518 Substituted cyclopentene derivatives and method for preparing the same |
01/27/2000 | WO2000003980A1 5-THIA-φ-SUBSTITUTED PHENYL-PROSTAGLANDIN E DERIVATIVES, PROCESS FOR PRODUCING THE SAME AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT |
01/26/2000 | EP0974580A1 Omega-cycloalkyl-prostaglandin E1 derivatives |
01/26/2000 | EP0643051B1 Process for Producing Alfa, Beta-Unsaturated Ketones |
01/11/2000 | US6013823 Trans-pentavalent 2-15-deoxy-16-hydroxy-16-methyl-PGE1 methyl ester (B-407) |
01/05/2000 | EP0968183A2 13-thia prostaglandins for use in glaucoma therapy |
12/29/1999 | WO1999067212A2 Active carbon filter as an oxidation inhibitor for prostane derivatives |
12/29/1999 | CA2335781A1 Oxidation inhibitors for prostane derivatives |
12/23/1999 | DE19828881A1 Industrial preparation of prostane derivatives, especially iloprost, having reduced content of decomposition products |
12/14/1999 | US6001877 Of given formula, which acts as an antagonist of leukotrienes; administering to treat leukotriene-b4 induced diseases, such as allergies and inflammation |
12/09/1999 | WO1999062877A1 Process for producing purified prostaglandin derivative |
12/02/1999 | WO1999061419A1 Prostaglandin derivative |
12/02/1999 | WO1999061029A1 Sleep inducing agent |
12/01/1999 | CN1237157A Lis-'delta'4 analogs of prostaglandins as ocular hypotensives |
11/23/1999 | US5990346 Prostaglandins and processes for production thereof |
11/23/1999 | US5990138 Cyclopentane (ene) heptenoic or heptanoic acids and derivatives thereof useful as therapeutic agents |
11/16/1999 | US5985920 Difluoroprostaglandin derivatives and their use |
11/02/1999 | US5977173 Aromatic C16 -C20 -substituted tetrahydro prostaglandins useful as FP agonists |
10/26/1999 | US5972991 Cyclopentane heptan(ene) oic acid, 2-heteroarylalkenyl derivatives as therapeutic agents |
10/07/1999 | WO1999050242A1 C11 oxymyl and hydroxylamino prostaglandins useful as fp agonists |
10/07/1999 | WO1999050241A1 C11 oxymyl and hydroxylamino prostaglandins useful as medicaments |
09/29/1999 | EP0944593A2 $i(CIS)-$g(D)?4 ANALOGS OF PROSTAGLANDINS AS OCULAR HYPOTENSIVES |
09/22/1999 | EP0943607A1 Process for the preparation of prostaglandins |
09/10/1999 | WO1999044990A1 Novel process |
09/10/1999 | CA2327332A1 Novel process |
09/01/1999 | EP0938472A2 15-fluoro prostaglandins as ocular hypotensives |
07/22/1999 | WO1999021830A8 Process for stereoselective synthesis of prostacyclin derivatives |
07/21/1999 | EP0930296A1 Fluorinated prostaglandin derivatives and medicines |
07/08/1999 | WO1999033794A1 φ-CYCLOALKYL-PROSTAGLANDIN E2 DERIVATIVES |