Patents
Patents for C07C 405 - Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins (3,702)
04/2001
04/04/2001EP1088816A2 Use of certain prostaglandin analogues to treat glaucoma and ocular hypertension
04/03/2001US6211233 Prostaglandin pharmaceutical compositions
03/2001
03/22/2001WO2001019790A1 Prostaglandin derivatives
03/22/2001WO2001019789A1 Prostaglandin derivatives
03/22/2001CA2384715A1 Prostaglandin derivatives
03/21/2001EP1085012A1 Process for producing purified prostaglandin derivative
03/20/2001US6204287 Treating vision defects
03/15/2001WO2001017957A1 Prostaglandin e analogues
03/15/2001CA2384148A1 Prostaglandin e analogues
03/14/2001EP1083168A1 Prostaglandin derivative
03/14/2001EP1082961A1 Sleep inducing agent
03/14/2001EP1082299A1 C11 oxymyl and hydroxylamino prostaglandins useful as medicaments
03/08/2001WO2000061588A8 Novel intermediate for the synthesis of prostaglandins
03/07/2001EP0847276B1 Method for effecting vasodilation with (1,5-inter)aryl prostaglandin derivatives
02/2001
02/27/2001CA2012267C Interphenylene 7-oxabicycloheptyl substituted heterocyclic amide prostaglandin analogs useful in the treatment of thrombotic and vasospastic disease
02/22/2001WO2001012596A1 Prostaglandin derivatives
02/22/2001CA2382265A1 Prostaglandin derivatives
02/20/2001US6191291 Oxidation of a substituted cyclopentadiene derivative with an oxidizing agent to form oxirane ring containing substituted cyclopentadiene derivative
02/14/2001EP1075464A1 Novel process
02/13/2001US6187813 Prostaglandin derivatives for the treatment of glaucoma or ocular hypertension
02/07/2001CN1283184A Process for stereo selective synthesis of prostacyclin derivatives
02/06/2001US6184250 Use of cloprostenol and fluprostenol analogues to treat glaucoma and ocular hypertension
01/2001
01/10/2001EP1066254A1 C11 oxymyl and hydroxylamino prostaglandins useful as fp agonists
01/09/2001US6172109 Side effect reduction; administering topically
01/02/2001US6169111 Conformationally rigid aryl prostaglandins for use in glaucoma therapy
12/2000
12/12/2000US6160129 Cyclopentane heptan(ene)oic acid, 2-heteroarylalkenyl derivatives as therapeutic agents
12/12/2000US6160013 14-aza prostaglandins for the treatment of glaucoma and ocular hypertension
12/12/2000US6160012 Leukotriene B4 derivatives, in particular oximo-LTB4 - antagonists
11/2000
11/22/2000CN1058706C Prostaglandin derivative
10/2000
10/19/2000WO2000061777A1 Process for the preparation of prostaglandin precursors
10/19/2000WO2000061588A1 Novel intermediate for the synthesis of prostaglandins
10/19/2000WO2000061550A1 Prostaglandin e1 derivatives
10/19/2000CA2369662A1 Prostaglandin e1 derivatives
10/11/2000EP1042283A1 $g(v)-CYCLOALKYL-PROSTAGLANDIN E 2? DERIVATIVES
10/11/2000CN1269786A Aromatic C16-C20 substituted tetrahydro prostaglandins useful as EP agonists
10/11/2000CN1269785A Aromatic C16-C20 substituted tetrahydro prostaglandius useful as EP agonists
10/11/2000CN1269784A Aromatic C16-C20 substituted tetrahydro prostagladins useful as FP agonists
10/11/2000CN1269783A Process for making epoxide intermediates
10/05/2000WO2000057701A1 Prostaglandin compounds, compositions and methods of treating peripheral vascular disease and pulmonary hypertension
10/05/2000CA2359652A1 Novel prostaglandin compounds and derivatives thereof, compositions containing the same and method of using the same for the treatment of peripheral vascular disease and pulmonaryhypertension
09/2000
09/27/2000EP0778269B1 Prostaglandins and process for producing the same
09/26/2000US6124344 Cyclopentane heptan(ene)oic acid, 2-heteroarylalkenyl derivatives as therapeutic agents
09/08/2000WO2000051980A1 C16 unsaturated fp-selective prostaglandins analogs
09/08/2000WO2000051979A1 C16 unsaturated fp-selective prostaglandins analogs
09/08/2000WO2000051978A1 Nitrosated and nitrosylated prostaglandins, compositions and metods of use
09/08/2000WO2000051977A1 Aldehyde intermediates for the preparation of prostaglandin derivatives
09/06/2000EP1032395A1 Cyclopentane heptan(ene)oic acid, 2-heteroarylalkenyl derivatives as therapeutic agents
08/2000
08/29/2000US6110969 Useful for prevention and/or treatment of autoimmune disease, organ transplantation, asthma, abnormal bone formation, neuron cell death, liver damage, abortion, premature birth or retina neuropathy of glaucoma
08/29/2000CA2012081C 2,5,6,7-tetranor-4,8-inter-m-phenylene pgi 2 derivatives
08/22/2000US6107338 Aromatic C16 -C20 -substituted tetrahydro prostaglandins useful as FP agonists
08/09/2000EP1025083A1 Process for stereoselective synthesis of prostacyclin derivatives
08/01/2000CA2019335C Phenylalkan (en)oic acids
07/2000
07/26/2000EP1021402A1 Aromatic c16-c20-substituted tetrahydro prostaglandins useful as fp agonists
07/19/2000CN1260778A Prostaglandin pharmaceutical compositions
06/2000
06/28/2000EP1012138A1 A process for making epoxide intermediates
06/28/2000EP1012137A1 Aromatic c 16?-c 20?-substituted tetrahydro prostaglandins useful as fp agonists
06/28/2000EP1012136A1 Aromatic c 16?-c 20?-substituted tetrahydro prostaglandins useful as fp agonists
06/14/2000EP1008588A1 11,15-o-dialkylprostaglandin e derivatives, process for producing the same, and drugs containing the same as the active ingredient
05/2000
05/30/2000US6069269 Process for the preparation of prostaglandin E1
05/23/2000US6066751 Intermediate can be coupled with oxygen, carbon, sulfur, and nitrogen nucleophiles, in the presence of a base or a lewis acid, in a ring-opening process to provide 13,14-dihydro prostaglandin a, e, and f derivatives
04/2000
04/13/2000WO2000020386A1 Stannane synthesis of prostanoids
04/11/2000US6048895 Antagonists of prostaglandin f for treating bone fractures and diseases and glaucoma
04/05/2000EP0989972A1 Prostaglandin pharmaceutical compositions
03/2000
03/30/2000WO1999067212A3 Active carbon filter as an oxidation inhibitor for prostane derivatives
03/28/2000US6043275 3,7-dithiaprostanoic acid derivative
03/23/2000WO2000015608A1 φ-SUBSTITUTED PHENYL-PROSTAGLANDIN E DERIVATIVES AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT
03/15/2000EP0985663A1 A 3.7-dithiaprostanoic acid derivative
03/14/2000US6037364 Cyclopentane heptan(ene)oic acid, 2-heteroarylalkenyl derivatives as therapeutic agents
03/08/2000EP0983235A2 Leukotriene b 4? derivatives, in particular oximo-ltb 4? antagonists
03/08/2000EP0983234A1 Leukotriene b 4? derivatives, in particular 7-methylcyclohexyl-ltb 4? antagonists
02/2000
02/29/2000US6030999 Prostaglandin derivatives for the treatment of glaucoma or ocular hypertension
02/15/2000US6025518 Substituted cyclopentene derivatives and method for preparing the same
01/2000
01/27/2000WO2000003980A1 5-THIA-φ-SUBSTITUTED PHENYL-PROSTAGLANDIN E DERIVATIVES, PROCESS FOR PRODUCING THE SAME AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT
01/26/2000EP0974580A1 Omega-cycloalkyl-prostaglandin E1 derivatives
01/26/2000EP0643051B1 Process for Producing Alfa, Beta-Unsaturated Ketones
01/11/2000US6013823 Trans-pentavalent 2-15-deoxy-16-hydroxy-16-methyl-PGE1 methyl ester (B-407)
01/05/2000EP0968183A2 13-thia prostaglandins for use in glaucoma therapy
12/1999
12/29/1999WO1999067212A2 Active carbon filter as an oxidation inhibitor for prostane derivatives
12/29/1999CA2335781A1 Oxidation inhibitors for prostane derivatives
12/23/1999DE19828881A1 Industrial preparation of prostane derivatives, especially iloprost, having reduced content of decomposition products
12/14/1999US6001877 Of given formula, which acts as an antagonist of leukotrienes; administering to treat leukotriene-b4 induced diseases, such as allergies and inflammation
12/09/1999WO1999062877A1 Process for producing purified prostaglandin derivative
12/02/1999WO1999061419A1 Prostaglandin derivative
12/02/1999WO1999061029A1 Sleep inducing agent
12/01/1999CN1237157A Lis-'delta'4 analogs of prostaglandins as ocular hypotensives
11/1999
11/23/1999US5990346 Prostaglandins and processes for production thereof
11/23/1999US5990138 Cyclopentane (ene) heptenoic or heptanoic acids and derivatives thereof useful as therapeutic agents
11/16/1999US5985920 Difluoroprostaglandin derivatives and their use
11/02/1999US5977173 Aromatic C16 -C20 -substituted tetrahydro prostaglandins useful as FP agonists
10/1999
10/26/1999US5972991 Cyclopentane heptan(ene) oic acid, 2-heteroarylalkenyl derivatives as therapeutic agents
10/07/1999WO1999050242A1 C11 oxymyl and hydroxylamino prostaglandins useful as fp agonists
10/07/1999WO1999050241A1 C11 oxymyl and hydroxylamino prostaglandins useful as medicaments
09/1999
09/29/1999EP0944593A2 $i(CIS)-$g(D)?4 ANALOGS OF PROSTAGLANDINS AS OCULAR HYPOTENSIVES
09/22/1999EP0943607A1 Process for the preparation of prostaglandins
09/10/1999WO1999044990A1 Novel process
09/10/1999CA2327332A1 Novel process
09/01/1999EP0938472A2 15-fluoro prostaglandins as ocular hypotensives
07/1999
07/22/1999WO1999021830A8 Process for stereoselective synthesis of prostacyclin derivatives
07/21/1999EP0930296A1 Fluorinated prostaglandin derivatives and medicines
07/08/1999WO1999033794A1 φ-CYCLOALKYL-PROSTAGLANDIN E2 DERIVATIVES
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