Patents for C07C 405 - Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins (3,702) |
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10/06/1992 | US5153220 Tetraenyl prostanoic acid derivatives as prodrugs for the treatment of peptic ulcer disease |
09/29/1992 | US5151444 Ocular hypotensive agents |
09/29/1992 | CA1308100C Processes and intermediates |
09/29/1992 | CA1308027C Stable prostaglandin-containing composition |
09/22/1992 | US5149711 2-cyclopentenone derivatives |
09/17/1992 | DE4108351A1 Neue leukotrien-b(pfeil abwaerts)4(pfeil abwaerts)-derivate, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel New leukotriene b (Down Arrow) 4 (down arrow) derivatives, process for their production and their use as drug |
09/16/1992 | EP0503887A2 Promotion of wound-healing with 15-keto-prostaglandin compounds |
09/13/1992 | WO1992016504A1 New leukotriene b4 derivatives, method for preparing them and their use as drugs |
09/13/1992 | CA2082818A1 Leukotriene b4 derivatives, method for preparing them and their use as drugs |
09/02/1992 | EP0501426A1 Alpha-methylenecyclopentanone derivative and process for producing the same |
08/20/1992 | WO1992013836A1 2-decarboxyl-2-hydroxyalkyl-5-trans prostaglandin f derivatives |
08/20/1992 | WO1992010473A3 2-decarboxyl-2-alkoxyalkyl prostaglandins as ocular hypotensives |
08/18/1992 | US5139491 2-decarboxyl-2-alkoxyalkyl prostaglandins as ocular hypotensives |
08/11/1992 | US5137915 Prostaglandins of the d series, and tranquilizers and soporifics containing the same |
07/29/1992 | EP0496548A1 Carbacyclin analogs |
07/23/1992 | WO1992008697A3 9-HALOGEN-11β-HYDROXY PROSTAGLANDIN DERIVATIVE, PROCESS FOR PRODUCING IT AND ITS USE AS A MEDICAMENT |
07/23/1992 | CA2056039A1 Carbacyclin analogs |
07/22/1992 | EP0495069A1 A method for synthesis of prostaglandin derivatives. |
07/08/1992 | EP0494063A2 Method for inhibiting IgE production |
07/08/1992 | EP0344235B1 Prostaglandin derivatives for the treatment of glaucoma or ocular hypertension |
06/28/1992 | CA2058457A1 Method for inhibiting ige production |
06/25/1992 | WO1992010473A2 2-decarboxyl-2-alkoxyalkyl prostaglandins as ocular hypotensives |
06/25/1992 | CA2096945A1 2-decarboxyl-2-alkoxyalkyl prostaglandins as ocular hypotensives |
06/23/1992 | US5124343 Prostaglandins; cardiovascular disorders, anticoagulants, hypotensive agents |
06/23/1992 | US5124267 Complexing with antibody; mass spectrometry |
06/17/1992 | DE4039893A1 Prepn. of cyclic cpds. which are biologically active - by reacting phenyl sulphoximine with alkal(ine earth) alcoholate or amine salt |
06/11/1992 | WO1992010193A2 Homo-prostaglandin derivatives as ocular hypotensives |
06/11/1992 | CA2096944A1 Homo-prostaglandin derivatives as ocular hypotensives |
06/09/1992 | US5120870 Emulsion of lipid containing a prostaglandin analogue |
06/09/1992 | US5120719 Conjugate of prostaglandin and polysaccharide |
05/29/1992 | WO1992008465A2 2-decarboxyl-2-aminoalkyl-prostaglandins as ocular hypotensives |
05/29/1992 | CA2095430A1 2-decarboxyl-2-aminoalkyl-prostaglandins as ocular hypotensives |
05/27/1992 | DE4037941A1 Cyclopentanetherderivate, verfahren zu ihrer herstellung und ihre pharmazeutische verwendung Cyclopentanetherderivate, processes for their preparation and their pharmaceutical use |
05/26/1992 | US5117042 15-keto-prostaglandin compound for improvement of encephalic function |
05/26/1992 | US5117037 Cis-bicyclo[4,3.0]non-2-end derivatives |
05/26/1992 | US5116869 2-substituted-2-cyclopentenones |
05/24/1992 | WO1992009573A2 Cyclopentane ether derivatives, methods for preparing them and their use in pharmaceuticals |
05/24/1992 | CA2096848A1 Cyclopentane ether derivatives, methods for preparing them and their use in pharmaceuticals |
05/19/1992 | US5114972 Synthesis and uses of new ascorbic acid derivatives which have anti-oxidant and anti-cancer activities |
05/19/1992 | CA1301100C Resolution of racemates of 3-acyloxy- bicyclo-[3.3.0]-octane-7-one-2-carboxylic acid esters by stereo-specific enzymatic or microbiological acylate hydrolysis |
05/14/1992 | DE4036140A1 9-halogen-11ss-hydroxy-prostaglandinderivate, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel 9-halo-11ß-hydroxy-prostaglandin derivatives, to processes for their preparation and their use as medicaments |
05/12/1992 | US5113014 Multistage reaction of cycloalkylsilyleneone in the presence of a Lewis acid with an unsaturated silyl ether or alcohol and an unsaturated aldehyde in a catalyst followed by acetylation and reduction |
05/10/1992 | WO1992008697A2 9-HALOGEN-11β-HYDROXY PROSTAGLANDIN DERIVATIVE, PROCESS FOR PRODUCING IT AND ITS USE AS A MEDICAMENT |
05/10/1992 | CA2073462A1 9-halogen-11beta-hydroxy-prostaglandin derivatives, process for their production and their use as pharmaceutical agents |
04/28/1992 | US5109021 Prostaglandin analogues, process for their preparation and pharmaceutical compositions containing them |
04/21/1992 | US5107014 Prostaglandin I analogue |
04/21/1992 | US5106869 Prostaglandins of the f series |
04/07/1992 | US5102793 Treating with a culture product to form optically active 3alpha-hydroxy prostacyclin compound |
03/19/1992 | WO1992004312A1 Process for making e/z mixtures of 2-(6-alkyl-bicyclo-[3.3.0]-octane-3-ylidene)-acetic acid derivatives with a preponderant proportion of the e-isomers |
03/12/1992 | DE4028864A1 Verfahren zur herstellung von e/z-mischungen von 2-(6-alkyl-bicyclo-(3.3.0)-octan-3-yliden) -essigsaeure-derivaten mit ueberwiegendem anteil des e-isomeren Process for the preparation of e / z of mixtures of 2- (6-alkyl-bicyclo (3.3.0) octane-3-ylidene) with a predominant proportion of e-isomeric acetic acid derivatives |
03/03/1992 | US5093490 Stereospecific synthesis |
02/26/1992 | EP0471856A1 15-deoxyprostaglandin derivative |
02/18/1992 | US5089524 Tetraenyl prostanoic acid derivatives as prodrugs for the treatment of peptic ulcer disease |
02/12/1992 | EP0470251A1 Liquid prostaglandin composition |
02/09/1992 | WO1992002496A1 A method for synthesis of prostaglandin derivatives |
02/04/1992 | US5086071 2,5,6,7-tetranor-4,8-inter-m-phenylene pgi2 derivatives |
02/04/1992 | US5086065 Leukotriene antagonists |
01/30/1992 | DE4024347A1 Cyclopentanderivate, verfahren zu ihrer herstellung und ihre pharmazeutische verwendung Cyclopentadiene derivatives, processes for their preparation and their pharmaceutical use |
01/30/1992 | DE4024345A1 Cyclopentenderivate, verfahren zu ihrer herstellung und ihre pharmazeutische verwendung Cyclopentene derivatives, processes for their preparation and their pharmaceutical use |
01/29/1992 | EP0324815B1 New 9-substituted carbocycline derivatives, process for manufacturing them and their use as drugs |
01/28/1992 | WO1992002495A1 Cyclopentane derivatives, process for producing them and their pharmaceutical use |
01/28/1992 | WO1992002494A1 Cyclopentane derivatives, process for producing them and their pharmaceutical use |
01/28/1992 | CA2088161A1 Cyclopentane derivatives, process for their production and their pharmaceutical use |
01/28/1992 | CA2088159A1 Cyclopentane derivatives, process for producing them and their pharmaceutical use |
01/14/1992 | US5081282 Prostaglandins |
01/08/1992 | EP0319576B1 Prostaglandin derivatives, processes for preparing them and pharmaceutical compositions containing said derivatives |
01/08/1992 | EP0147461B1 11-halogene-prostane derivatives, process for obtaining them and utilization thereof as drugs |
01/07/1992 | US5079259 Pharmaceutically active 9-chloroprostaglandins |
12/31/1991 | US5077309 Thromboxane a2 antagonist |
12/24/1991 | US5075478 Process for preparing prostaglandins |
12/17/1991 | US5073569 Prostaglandins of the d series, and tranquilizers and soporifics containing the same |
12/10/1991 | US5072010 Reacting zirconium and lithium compounds, reacting product with copper/lithium complex |
11/27/1991 | EP0458641A2 Use of prostaglandin derivatives in the treatment of congestive heart failure |
11/13/1991 | EP0455899A1 Prostaglandin I analogue |
11/06/1991 | EP0455264A2 Ocular hypotensive agents |
10/23/1991 | EP0452843A2 Process for preparing prostaglandin analogs using organozirconium compounds |
10/17/1991 | WO1991015493A1 Transmetalations from zirconium to copper intermediates |
10/15/1991 | US5057621 11-substituted-16-phenoxy and 16-substituted phenoxy-prostatrienoic acid derivatives |
10/08/1991 | US5055604 Process for preparing prostaglandin analogs using organozirconium compounds |
10/08/1991 | US5055592 For preparation of prostaglandin derivatives |
10/08/1991 | CA1290331C Prostacyclins and pharmaceuticals containing the same |
10/02/1991 | EP0448726A1 2-substituted 2-cyclopentenone and carcinostatic agent and osteogenesis promoter containing the same as active ingredient |
10/02/1991 | DE4010355A1 Bicyclo(3.3.0)octan-derivate, verfahren zu ihrer herstellung und ihre pharmazeutische verwendung Bicyclo (3.3.0) octane derivatives, process for their production and their pharmaceutical use |
10/01/1991 | US5053526 Pharmaceuticals containing prostaglandin I2 |
10/01/1991 | US5053400 Anticoagulants; hypotensive agents; bronchodilator agents; tissue specificity |
09/29/1991 | WO1991014675A1 Bicyclo[3.3.)]octane derivatives, process for producing them and their pharmaceutical use |
09/29/1991 | CA2058922A1 Bicyclo{3.3.0}octane derivatives, process for their production and their pharmaceutical use |
09/19/1991 | WO1991013869A1 15-deoxyprostaglandin derivative |
09/11/1991 | EP0445948A2 Prostaglandins for inhibiting cartilage damage |
09/04/1991 | EP0444844A2 New 15-dehydroxy-16-oxoprostaglandins |
08/29/1991 | CA2037088A1 Prostaglandins for inhibiting cartilage damage |
07/03/1991 | EP0435443A2 Use of 15-keto-prostaglandin compound for improvement of encephalic function |
07/03/1991 | EP0434832A1 D8- and D9-PROSTAGLANDINE DERIVATES, THEIR PROCESS OF PRODUCTION AND THEIR PHARMACEUTICAL USE. |
07/03/1991 | EP0434707A1 6-oxo-9-fluor-prostaglandin derivatives, process for producing them and their use as drugs |
07/02/1991 | US5028733 Prostaglandins |
06/27/1991 | WO1991009012A1 Processes for preparing prostaglandins |
06/18/1991 | US5025034 Prostaglandins |
06/12/1991 | EP0431571A2 Cis-Bicyclo[4.3.0]non-2-ene derivatives |
06/11/1991 | US5023273 6-oxoprostaglandin E derivatives, process for their production and their pharmaceutical use |
05/15/1991 | EP0427708A1 Isocarbacyclin derivatives |