Patents
Patents for C07C 405 - Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins (3,702)
10/1992
10/06/1992US5153220 Tetraenyl prostanoic acid derivatives as prodrugs for the treatment of peptic ulcer disease
09/1992
09/29/1992US5151444 Ocular hypotensive agents
09/29/1992CA1308100C Processes and intermediates
09/29/1992CA1308027C Stable prostaglandin-containing composition
09/22/1992US5149711 2-cyclopentenone derivatives
09/17/1992DE4108351A1 Neue leukotrien-b(pfeil abwaerts)4(pfeil abwaerts)-derivate, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel New leukotriene b (Down Arrow) 4 (down arrow) derivatives, process for their production and their use as drug
09/16/1992EP0503887A2 Promotion of wound-healing with 15-keto-prostaglandin compounds
09/13/1992WO1992016504A1 New leukotriene b4 derivatives, method for preparing them and their use as drugs
09/13/1992CA2082818A1 Leukotriene b4 derivatives, method for preparing them and their use as drugs
09/02/1992EP0501426A1 Alpha-methylenecyclopentanone derivative and process for producing the same
08/1992
08/20/1992WO1992013836A1 2-decarboxyl-2-hydroxyalkyl-5-trans prostaglandin f derivatives
08/20/1992WO1992010473A3 2-decarboxyl-2-alkoxyalkyl prostaglandins as ocular hypotensives
08/18/1992US5139491 2-decarboxyl-2-alkoxyalkyl prostaglandins as ocular hypotensives
08/11/1992US5137915 Prostaglandins of the d series, and tranquilizers and soporifics containing the same
07/1992
07/29/1992EP0496548A1 Carbacyclin analogs
07/23/1992WO1992008697A3 9-HALOGEN-11β-HYDROXY PROSTAGLANDIN DERIVATIVE, PROCESS FOR PRODUCING IT AND ITS USE AS A MEDICAMENT
07/23/1992CA2056039A1 Carbacyclin analogs
07/22/1992EP0495069A1 A method for synthesis of prostaglandin derivatives.
07/08/1992EP0494063A2 Method for inhibiting IgE production
07/08/1992EP0344235B1 Prostaglandin derivatives for the treatment of glaucoma or ocular hypertension
06/1992
06/28/1992CA2058457A1 Method for inhibiting ige production
06/25/1992WO1992010473A2 2-decarboxyl-2-alkoxyalkyl prostaglandins as ocular hypotensives
06/25/1992CA2096945A1 2-decarboxyl-2-alkoxyalkyl prostaglandins as ocular hypotensives
06/23/1992US5124343 Prostaglandins; cardiovascular disorders, anticoagulants, hypotensive agents
06/23/1992US5124267 Complexing with antibody; mass spectrometry
06/17/1992DE4039893A1 Prepn. of cyclic cpds. which are biologically active - by reacting phenyl sulphoximine with alkal(ine earth) alcoholate or amine salt
06/11/1992WO1992010193A2 Homo-prostaglandin derivatives as ocular hypotensives
06/11/1992CA2096944A1 Homo-prostaglandin derivatives as ocular hypotensives
06/09/1992US5120870 Emulsion of lipid containing a prostaglandin analogue
06/09/1992US5120719 Conjugate of prostaglandin and polysaccharide
05/1992
05/29/1992WO1992008465A2 2-decarboxyl-2-aminoalkyl-prostaglandins as ocular hypotensives
05/29/1992CA2095430A1 2-decarboxyl-2-aminoalkyl-prostaglandins as ocular hypotensives
05/27/1992DE4037941A1 Cyclopentanetherderivate, verfahren zu ihrer herstellung und ihre pharmazeutische verwendung Cyclopentanetherderivate, processes for their preparation and their pharmaceutical use
05/26/1992US5117042 15-keto-prostaglandin compound for improvement of encephalic function
05/26/1992US5117037 Cis-bicyclo[4,3.0]non-2-end derivatives
05/26/1992US5116869 2-substituted-2-cyclopentenones
05/24/1992WO1992009573A2 Cyclopentane ether derivatives, methods for preparing them and their use in pharmaceuticals
05/24/1992CA2096848A1 Cyclopentane ether derivatives, methods for preparing them and their use in pharmaceuticals
05/19/1992US5114972 Synthesis and uses of new ascorbic acid derivatives which have anti-oxidant and anti-cancer activities
05/19/1992CA1301100C Resolution of racemates of 3-acyloxy- bicyclo-[3.3.0]-octane-7-one-2-carboxylic acid esters by stereo-specific enzymatic or microbiological acylate hydrolysis
05/14/1992DE4036140A1 9-halogen-11ss-hydroxy-prostaglandinderivate, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel 9-halo-11ß-hydroxy-prostaglandin derivatives, to processes for their preparation and their use as medicaments
05/12/1992US5113014 Multistage reaction of cycloalkylsilyleneone in the presence of a Lewis acid with an unsaturated silyl ether or alcohol and an unsaturated aldehyde in a catalyst followed by acetylation and reduction
05/10/1992WO1992008697A2 9-HALOGEN-11β-HYDROXY PROSTAGLANDIN DERIVATIVE, PROCESS FOR PRODUCING IT AND ITS USE AS A MEDICAMENT
05/10/1992CA2073462A1 9-halogen-11beta-hydroxy-prostaglandin derivatives, process for their production and their use as pharmaceutical agents
04/1992
04/28/1992US5109021 Prostaglandin analogues, process for their preparation and pharmaceutical compositions containing them
04/21/1992US5107014 Prostaglandin I analogue
04/21/1992US5106869 Prostaglandins of the f series
04/07/1992US5102793 Treating with a culture product to form optically active 3alpha-hydroxy prostacyclin compound
03/1992
03/19/1992WO1992004312A1 Process for making e/z mixtures of 2-(6-alkyl-bicyclo-[3.3.0]-octane-3-ylidene)-acetic acid derivatives with a preponderant proportion of the e-isomers
03/12/1992DE4028864A1 Verfahren zur herstellung von e/z-mischungen von 2-(6-alkyl-bicyclo-(3.3.0)-octan-3-yliden) -essigsaeure-derivaten mit ueberwiegendem anteil des e-isomeren Process for the preparation of e / z of mixtures of 2- (6-alkyl-bicyclo (3.3.0) octane-3-ylidene) with a predominant proportion of e-isomeric acetic acid derivatives
03/03/1992US5093490 Stereospecific synthesis
02/1992
02/26/1992EP0471856A1 15-deoxyprostaglandin derivative
02/18/1992US5089524 Tetraenyl prostanoic acid derivatives as prodrugs for the treatment of peptic ulcer disease
02/12/1992EP0470251A1 Liquid prostaglandin composition
02/09/1992WO1992002496A1 A method for synthesis of prostaglandin derivatives
02/04/1992US5086071 2,5,6,7-tetranor-4,8-inter-m-phenylene pgi2 derivatives
02/04/1992US5086065 Leukotriene antagonists
01/1992
01/30/1992DE4024347A1 Cyclopentanderivate, verfahren zu ihrer herstellung und ihre pharmazeutische verwendung Cyclopentadiene derivatives, processes for their preparation and their pharmaceutical use
01/30/1992DE4024345A1 Cyclopentenderivate, verfahren zu ihrer herstellung und ihre pharmazeutische verwendung Cyclopentene derivatives, processes for their preparation and their pharmaceutical use
01/29/1992EP0324815B1 New 9-substituted carbocycline derivatives, process for manufacturing them and their use as drugs
01/28/1992WO1992002495A1 Cyclopentane derivatives, process for producing them and their pharmaceutical use
01/28/1992WO1992002494A1 Cyclopentane derivatives, process for producing them and their pharmaceutical use
01/28/1992CA2088161A1 Cyclopentane derivatives, process for their production and their pharmaceutical use
01/28/1992CA2088159A1 Cyclopentane derivatives, process for producing them and their pharmaceutical use
01/14/1992US5081282 Prostaglandins
01/08/1992EP0319576B1 Prostaglandin derivatives, processes for preparing them and pharmaceutical compositions containing said derivatives
01/08/1992EP0147461B1 11-halogene-prostane derivatives, process for obtaining them and utilization thereof as drugs
01/07/1992US5079259 Pharmaceutically active 9-chloroprostaglandins
12/1991
12/31/1991US5077309 Thromboxane a2 antagonist
12/24/1991US5075478 Process for preparing prostaglandins
12/17/1991US5073569 Prostaglandins of the d series, and tranquilizers and soporifics containing the same
12/10/1991US5072010 Reacting zirconium and lithium compounds, reacting product with copper/lithium complex
11/1991
11/27/1991EP0458641A2 Use of prostaglandin derivatives in the treatment of congestive heart failure
11/13/1991EP0455899A1 Prostaglandin I analogue
11/06/1991EP0455264A2 Ocular hypotensive agents
10/1991
10/23/1991EP0452843A2 Process for preparing prostaglandin analogs using organozirconium compounds
10/17/1991WO1991015493A1 Transmetalations from zirconium to copper intermediates
10/15/1991US5057621 11-substituted-16-phenoxy and 16-substituted phenoxy-prostatrienoic acid derivatives
10/08/1991US5055604 Process for preparing prostaglandin analogs using organozirconium compounds
10/08/1991US5055592 For preparation of prostaglandin derivatives
10/08/1991CA1290331C Prostacyclins and pharmaceuticals containing the same
10/02/1991EP0448726A1 2-substituted 2-cyclopentenone and carcinostatic agent and osteogenesis promoter containing the same as active ingredient
10/02/1991DE4010355A1 Bicyclo(3.3.0)octan-derivate, verfahren zu ihrer herstellung und ihre pharmazeutische verwendung Bicyclo (3.3.0) octane derivatives, process for their production and their pharmaceutical use
10/01/1991US5053526 Pharmaceuticals containing prostaglandin I2
10/01/1991US5053400 Anticoagulants; hypotensive agents; bronchodilator agents; tissue specificity
09/1991
09/29/1991WO1991014675A1 Bicyclo[3.3.)]octane derivatives, process for producing them and their pharmaceutical use
09/29/1991CA2058922A1 Bicyclo{3.3.0}octane derivatives, process for their production and their pharmaceutical use
09/19/1991WO1991013869A1 15-deoxyprostaglandin derivative
09/11/1991EP0445948A2 Prostaglandins for inhibiting cartilage damage
09/04/1991EP0444844A2 New 15-dehydroxy-16-oxoprostaglandins
08/1991
08/29/1991CA2037088A1 Prostaglandins for inhibiting cartilage damage
07/1991
07/03/1991EP0435443A2 Use of 15-keto-prostaglandin compound for improvement of encephalic function
07/03/1991EP0434832A1 D8- and D9-PROSTAGLANDINE DERIVATES, THEIR PROCESS OF PRODUCTION AND THEIR PHARMACEUTICAL USE.
07/03/1991EP0434707A1 6-oxo-9-fluor-prostaglandin derivatives, process for producing them and their use as drugs
07/02/1991US5028733 Prostaglandins
06/1991
06/27/1991WO1991009012A1 Processes for preparing prostaglandins
06/18/1991US5025034 Prostaglandins
06/12/1991EP0431571A2 Cis-Bicyclo[4.3.0]non-2-ene derivatives
06/11/1991US5023273 6-oxoprostaglandin E derivatives, process for their production and their pharmaceutical use
05/1991
05/15/1991EP0427708A1 Isocarbacyclin derivatives
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