Patents
Patents for C07C 405 - Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins (3,702)
08/1995
08/09/1995EP0666256A1 Prostaglandine derivative
08/09/1995EP0665751A1 Novel 7-(5-substituted cyclopentyl) and (5-substituted cyclopentenyl) heptyl alcohols, heptylamines and heptanoic acid amines, and method of lowering intraocular pressure in the eye of a mammal by administration of these novel compounds
08/09/1995EP0562016B1 2-decarboxyl-2-alkoxyalkyl prostaglandins as ocular hypotensives
08/09/1995CN1106385A 13,14-dihydro-PGF2beta and its isopropyl ester
08/03/1995WO1995020563A1 New leukotriene b4 derivatives, methods of preparing them and their use as drugs
08/03/1995WO1995020562A1 Leukotriene b4 derivatives, methods of preparing them and their use as drugs
08/03/1995CA2182191A1 New leukotriene b4 derivatives, methods of preparing them and their use as drugs
07/1995
07/27/1995WO1995019964A1 Ep2-receptor agonists as agents for lowering intraocular pressure
07/26/1995EP0664281A1 ISOCARBACYCLIN WITH MODIFIED $g(a)-CHAIN AND PROCESS FOR PRODUCING THE SAME
07/20/1995WO1995019340A1 7-thiaprostaglandins and process for producing the same
07/20/1995CA2158350A1 7-thiaprostaglandins and method of production thereof
07/12/1995EP0662075A1 Prostaglandin analog for treating osteoporosis
07/06/1995WO1995018102A1 Cyclopentane(ene) heptenoic or heptanoic acids and derivatives thereof useful as therapeutic agents
07/06/1995WO1995018101A1 Prostaglandin derivative, salt thereof, and use thereof
07/06/1995CA2179981A1 Prostaglandin derivative, salt thereof, and use thereof
07/05/1995EP0660716A1 Non-acidic cyclopentane heptanoic acid, 2-cycloalkyl or arylalkyl derivatives as therapeutic agents
06/1995
06/28/1995EP0659728A1 4-hydroxy-2-cyclopentenone derivative and carcinostatic and osteogenesis promoter containing the same
06/27/1995US5428062 Side effect reduction
06/22/1995DE4343776A1 New oxo-prostaglandin sulphonamide analogues
06/20/1995US5426115 Use of 15-keto-prostaglandin compound for improvement of encephalic function
06/16/1995CA2138181A1 Use of certain prostaglandin analogues to treat glaucoma and ocular hypertension
06/14/1995EP0656889A1 9-chloroprostaglandin esters and amides and their use in the preparation of drugs
06/06/1995US5422368 With omega chain having a ring as end group, side effect reduction
05/1995
05/24/1995CN1028529C Interphenylene 7-oxabicycloheptyl substituted heterocyclic amide prostaglandin analogs useful in treatment of thrombotic and vasospastic disease
05/10/1995EP0652211A1 Prostaglandin derivative
05/10/1995EP0652208A1 Phenylalkan(en)oic acids with leukotriene B4 antagonistic activity
05/10/1995EP0510154B1 9-HALOGEN-11(Beta)-HYDROXY PROSTAGLANDIN DERIVATIVE, PROCESS FOR PRODUCING IT AND ITS USE AS A MEDICAMENT
05/09/1995US5414016 New leukotriene-B4 derivatives, process for their production and their use as pharmaceutical agents
05/03/1995EP0541594B1 Cyclopentane derivatives, process for producing them and their pharmaceutical use
04/1995
04/27/1995WO1995011229A1 1,11-DIESTERS OF PROSTAGLANDIN-F2α HAVING A POLAR ESTER GROUP AT C-1
04/27/1995CA2174241A1 1,11-diesters of prostaglandin-f2.alpha. having a polar ester group at c-1
04/25/1995US5409911 Prostaglandin analog for treating osteoporosis
04/11/1995US5405988 9-substituted bicyclo[3.3.0]octane derivatives, process for their production and their pharmaceutical use
04/11/1995US5405870 Carbacyclin compounds; pharmaceutical compositions and method of use
03/1995
03/29/1995EP0645056A1 Micromechanical thermoelectric sensor element.
03/22/1995EP0471856B1 15-deoxyprostaglandin derivative
03/15/1995EP0643063A2 Process for preparing a higher cuprate complex
03/15/1995EP0643051A1 PROCESS FOR PRODUCING $g(a),$g(b)-UNSATURATED KETONE
03/09/1995WO1995006634A1 New 9-chloro-prostaglandin derivatives
03/09/1995CA2170613A1 New 9-chloro-prostaglandin derivatives
02/1995
02/23/1995WO1995005178A1 Cyclopentane(ene) heptanoic or cyclopentane(ene) heptenoic acid, 2-hydrocarbyl sulfonamidomethyl and derivatives thereof as therapeutic agents
02/23/1995CA2169744A1 Cyclopentane(ene) heptanoic or cyclopentane(ene) heptenoic acid, 2-hydrocarbyl sulfonamidomethyl and derivatives thereof as therapeutic agents
02/22/1995EP0639563A2 Use of cloprostenol, fluprostenol and their analogues for the manufacture of a medicament for the treatment of glaucoma and ocular hypertension
02/14/1995CA1334425C Precursor of prostaglandin and production thereof
02/07/1995US5387608 Ocular hypotensive agents for treatment of glaucoma; smooth muscle relaxants
01/1995
01/31/1995US5385945 7-(5-substituted cyclopentyl) and (5-substituted cyclopentenyl) heptyl alcohols, heptylamines and heptanoic acid amides, and method of lowering intraocular pressure in the eye of a mammal by administration of these novel compounds
01/10/1995US5380900 α-methylenecyclopentanone derivative and process for producing the same
01/10/1995US5380709 Prostaglandins E and anti ulcers containing same
12/1994
12/28/1994EP0523151B1 Transmetalations from zirconium to copper intermediates
12/27/1994US5376683 Δ8- and Δ9-prostaglandin derivatives, process for their production and their pharmaceutical use
12/20/1994US5374654 Anticogulants, vasodilating to lower blood pressure, antisecretory agents, chemical linkage to polymeric carriers or proteins to produce antibodies
12/15/1994CA2125804A1 13,14-dihydro-pgf2.beta. and its isopropyl ester
12/14/1994EP0628545A1 13,14-Dihydro-PGF2BETA and its isopropyl ester
12/08/1994WO1994027962A1 Prostaglandin e1 analog
12/07/1994EP0627416A1 Process for producing prostaglandin e
11/1994
11/17/1994EP0624574A2 Novel prostaglandin analogue
10/1994
10/25/1994US5359095 Hydrogenation of doulbe bond in intermediate compound without deoxygenatio of allytic alcohol
10/18/1994CA1332603C 2-substituted-2-cyclopentenones
10/12/1994EP0619296A1 Phenylalkan(en)oic acids with leukotriene B4 antagonistic activity
10/04/1994US5352708 Non-acidic cyclopentane heptanoic acid, 2-cycloalkyl or arylalkyl derivatives as therapeutic agents
09/1994
09/14/1994EP0614457A1 Leukotriene-b 4? derivatives, process for preparing the same and medicaments.
09/01/1994WO1994019319A1 Process for producing intermediate for 13,14-didehydroprostaglandin e
09/01/1994CA2156304A1 Process for producing intermediate for 13,14-didehydroprostaglandin e
08/1994
08/16/1994US5338844 2-substituted-2-cyclopentenone compound and anticancer agent and bone formation accelerator comprising same as active ingredient
08/10/1994EP0587770A4 Platelet receptor antagonists useful in detecting intravascular platelet aggregation
08/03/1994EP0608241A1 Method and composition for treatment of gastric and duodenal disorders and new pge 2?-derivatives
08/02/1994US5334369 Platelet receptor antagonists useful in detecting intravascular platelet aggregation
07/1994
07/26/1994US5332730 Azido derivatives of cyclopentane heptanoic or heptenoic acid
07/12/1994US5329035 Process for producing 2,3-disubstituted-4-substituted cyclopentanones, enantiomorphs, or mixtures thereof
07/12/1994US5328933 Cyclopentane heptenylnitro and heptanylnitro-2-aliphatic or aryl aliphatic derivatives and homologues
06/1994
06/29/1994EP0603800A1 Prostaglandin combinations in glaucoma therapy
06/23/1994DE4236540A1 New leukotriene B4 derivs.
06/22/1994CA2112027A1 Prostaglandin combinations in glaucoma therapy
06/16/1994DE4242390A1 New cycloaliphatic leukotriene-B4 derivs. - used as leukotriene antagonists e.g. for treating inflammation, allergy, skin disease or leukaemia
05/1994
05/26/1994WO1994008586A3 Azido derivatives of cyclopentane heptanoic or heptenoic acid
05/25/1994EP0434833B1 9-fluor-prostaglandine derivates, their process of production and their pharmaceutical use
05/18/1994EP0597095A1 Prostaglandin e1 analogue
05/17/1994US5312842 Cyclopentane heptenylsulfinylalkyl and heptanylsulfinylalkyl-2-aliphatic or aryl aliphatic derivatives
05/17/1994US5312832 Ocular hypotensive 2-decarboxyl-2-acylthioalkyl prostaglandin derivatives
05/11/1994WO1994010141A1 Cyclopentane heptenylnitro and heptanylnitro-2-aliphatic or arylaliphatic derivatives and homologous
05/11/1994WO1994009788A1 Cyclopentane heptenylsulfinylalkyl and heptanylsulfinylalkyl-2-aliphatic or aryl aliphatic derivatives
05/04/1994EP0434832B1 D8- and D9-PROSTAGLANDINE DERIVATES, THEIR PROCESS OF PRODUCTION AND THEIR PHARMACEUTICAL USE
04/1994
04/28/1994WO1994008961A1 Prostaglandin e1 analog
04/28/1994WO1994008960A1 Prostaglandin e1 analog
04/28/1994WO1994008959A1 Prostaglandine derivative
04/28/1994WO1994008587A1 Novel 7-(5-substituted cyclopentyl) and (5-substituted cyclopentenyl) heptyl alcohols, heptylamines and heptanoic acid amines, and method of lowering intraocular pressure in the eye of a mammal by administration of these novel compounds
04/28/1994WO1994008586A2 Azido derivatives of cyclopentane heptanoic or heptenoic acid
04/28/1994CA2147476A1 Prostaglandin derivatives
04/28/1994CA2147461A1 Prostaglandin e1 analogues
04/14/1994WO1994007884A1 PROCESS FOR PRODUCING α,β-UNSATURATED KETONE
04/14/1994WO1994007838A1 ISOCARBACYCLIN WITH MODIFIED α-CHAIN AND PROCESS FOR PRODUCING THE SAME
04/14/1994CA2146361A1 .alpha.-chain-modified isocarbacyclins and process for the production thereof
04/13/1994EP0591532A1 Prostaglandin e 1? analogue
03/1994
03/31/1994WO1994006750A1 Prostaglandin analog for treating osteoporosis
03/31/1994WO1994006433A1 Non-acidic cyclopentane heptanoic acid, 2-cycloalkyl or arylalkyl derivatives as therapeutic agents
03/31/1994WO1994006291A1 Solid phase and combinatorial synthesis of compounds on a solid support
03/31/1994CA2144093A1 Prostaglandin analog for treating osteoporosis
03/29/1994CA1328075C Ocular hypotensive agents
03/23/1994EP0587770A1 Platelet receptor antagonists useful in detecting intravascular platelet aggregation
03/22/1994US5296504 Prostaglandin derivatives for the treatment of glaucoma or ocular hypertension
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