Patents for C07C 405 - Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins (3,702) |
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02/18/2015 | EP2837621A1 Processes for the preparation of isomer free prostaglandins |
02/17/2015 | US8957240 Method for the purification of prostaglandins |
02/03/2015 | CA2847985C Process for stereoselective synthesis of prostacyclin derivatives |
02/03/2015 | CA2589864C 12-aryl prostaglandin analogs |
01/29/2015 | US20150031898 Process for preparation of prostaglandin f2 alpha analogues |
01/15/2015 | US20150018400 Treatment of inflammatory bowel disease |
01/14/2015 | EP2822927A1 PROCESS FOR PREPARATION OF PROSTAGLANDIN F2alpha ANALOGUES |
01/06/2015 | US8927280 Compositions and methods for promoting the generation of definitive endoderm |
10/21/2014 | US8865766 Ester derivatives of bimatoprost compositions and methods |
09/30/2014 | US8846958 Process for the preparation of lubiprostone |
09/24/2014 | EP2781505A1 Positively charged water-soluble prodrugs of prostaglandins and related compounds with very high skin penetration rates |
09/23/2014 | CA2628413C Prostaglandins and analogues as agents for lowering intraocular pressure |
09/02/2014 | CA2549056C Prostaglandin synthesis |
08/21/2014 | US20140235665 Anti-constipation composition |
07/03/2014 | WO2014106204A1 Tromethamine salt of bimatoprost acid in crystalline form, methods for preparation, and methods for use thereof |
06/19/2014 | US20140171496 Composition and method for promoting hair growth |
06/19/2014 | US20140171388 Compound for treating cartilage disorders |
06/18/2014 | DE69331233C5 2-zykloalkyl-oder arylalkyl-derivate von nicht-säure, zyklopentane-heptanoic-säure 2-cycloalkyl or arylalkyl-derivatives of non-acid, heptanoic acid-zyklopentane |
06/17/2014 | US8754122 Geminal dialkyl prostanoids |
06/11/2014 | EP2740724A1 Compound for treating cartilage disorders |
06/10/2014 | US8748657 Process to prepare treprostinil |
06/05/2014 | WO2014083367A1 Process for the preparation of travoprost |
06/03/2014 | CA2588056C 2,3,4-substituted cyclopentanones as therapeutic agents |
05/28/2014 | EP2735566A1 Method for preparing prostaglandin derivative |
05/28/2014 | CN101379051B 用于制备前列腺素衍生物的方法 The method for preparing prostaglandin derivatives for |
05/21/2014 | CN103813809A 聚合物缀合的前列腺素类似物 Polymer conjugated prostaglandin analogs |
05/15/2014 | US20140135503 Novel processes for the preparation of prostaglandin amides |
05/14/2014 | CN103787942A 一种制备鲁比前列酮的中间体、其制备方法以及通过其制备鲁比前列酮的方法 An intermediate lubiprostone preparation, preparation and a method for their preparation by lubiprostone in |
05/07/2014 | CN102007098B 治疗性的取代的环戊烷 Treatment of a substituted cyclopentane |
05/06/2014 | CA2307163C Process for stereoselective synthesis of prostacyclin derivatives |
04/30/2014 | EP2723714A1 Novel processes for the preparation of prostaglandin amides |
04/30/2014 | CN102099330B Nitric oxide donating prostamides |
04/01/2014 | US8686035 Composition and method for promoting hair growth |
03/26/2014 | CN103664726A Deuterated bimatoprost or derivative thereof and preparation method and application of deuterated bimatoprost or derivative thereof |
03/25/2014 | US8680327 Methods for manufacturing tetranor-prostaglandin D, J, E, A and F metabolites |
03/20/2014 | WO2014040457A1 Intermediate of limaprost, preparation method thereof and preparation method of limaprost therefrom |
03/19/2014 | CN103649047A Novel processes for the preparation of prostaglandin amides |
03/12/2014 | CN102050808B Preparation method for prostaglandin intermediate |
02/19/2014 | EP2696899A1 Polymer conjugated prostaglandin analogues |
02/19/2014 | CN103588692A Method of purification of prostaglandins including fluorine atoms by preparative high performance liquid chromatography |
02/13/2014 | WO2014023256A1 Process for preparation of tafluprost and intermediates thereof |
02/12/2014 | CN103570599A Preparation method of prostaglandin A1 |
02/11/2014 | US8648213 Prostamides for the treatment of glaucoma and related diseases |
01/30/2014 | US20140031428 Method for treating schizophrenia |
01/22/2014 | CN102336693B Carboprost tromethamine crystals, preparation method and application thereof |
01/09/2014 | WO2012164324A9 Novel processes for the preparation of prostaglandin amides |
12/31/2013 | US8618086 Compositions and methods for treating hair loss using C16-C20 aromatic tetrahydro prostaglandins |
12/25/2013 | EP2675786A1 Ester derivatives of bimatoprost compositions and methods |
12/18/2013 | CN103459368A Ester derivatives of bimatoprost compositions and methods |
12/05/2013 | US20130324606 Ester Derivatives of Bimatoprost Compositions and Methods |
11/07/2013 | WO2013164729A1 An improved and scalable process for preparation of prostaglandin derivatives and intermediates thereof |
10/30/2013 | CN103373947A Green synthesis method for dinoprostone (prostaglandin PGE2) |
10/01/2013 | US8546114 Processes for the preparation of optically active cyclopentenones and cyclopentenones prepared therefrom |
09/25/2013 | CN103319390A Alprostadil compound and composition thereof |
09/12/2013 | WO2013133730A1 PROCESS FOR PREPARATION OF PROSTAGLANDIN F2α ANALOGUES |
09/11/2013 | CN103288698A Novel method for synthetizing prostaglandin analogue |
09/10/2013 | US8530519 Method for promoting upper gastrointestinal bicarbonate secretion |
09/04/2013 | CN101721708B ED-71 preparation |
08/21/2013 | EP2628725A1 Prostaglandins and analogues as agents for lowering intraocular pressure |
08/21/2013 | CN102050772B Bimatoprost crystal as well as preparation method and purposes thereof |
08/20/2013 | CA2515631C 10,10-dialkyl prostanoic acid derivatives as agents for lowering intraocular pressure |
08/15/2013 | WO2013118058A1 Amine salts of prostaglandin analogs |
08/13/2013 | US8507274 Compositions and methods for promoting the generation of definitive endoderm |
08/08/2013 | US20130202704 Use of mexiprostil in the treatment of inflammatory bowel disease and/or of irritable bowel syndrome |
08/06/2013 | US8501793 Blood flow promoters for cauda equina tissues |
07/18/2013 | WO2013104317A1 Crystal form of prostaglandin analogue, and preparation method and use thereof |
07/03/2013 | CN101903324B Process to prepare treprostinil, the active ingredient in Remodulin |
06/27/2013 | WO2013093528A1 Process for the preparation of travoprost |
06/12/2013 | CN102126998B Endothelin antagonist |
06/12/2013 | CN101795692B Therapeutic substituted cyclopentanes for reducing intraocular pressure |
06/04/2013 | US8455547 Substituted cyclopentanes having prostaglandin activity |
05/22/2013 | CN101921220B Pharmaceutical compositions for treating diseases with bone mass loss having EP4 agonist as the active ingredient |
05/16/2013 | WO2013040068A3 Process for preparing synthetic prostacyclins |
05/07/2013 | CA2534645C Composition and method for promoting hair growth |
04/24/2013 | CN103058907A Preparation method of lubiprostone or midbody thereof |
04/24/2013 | CN101265226B Compounds and methods for delivery of prostacyclin analogs |
04/17/2013 | EP2580192A2 Methods for manufacturing tetranor-prostaglandin d, j, e, a and f metabolites |
04/17/2013 | CN102020625B High-purity lubiprostone, preparation method and application thereof |
04/09/2013 | US8414904 Ophthalmic oil-in-water emulsions containing prostaglandins |
03/21/2013 | WO2013040068A2 Process for preparing synthetic prostacyclins |
03/21/2013 | US20130072695 Prostaglandin synthesis and intermediates for use therein |
03/06/2013 | CN102351767B Alprostadil compound and preparation method thereof |
02/14/2013 | WO2013021935A1 Compound for treating cartilage disorders |
02/07/2013 | US20130035393 Method for treating schizophrenia |
02/06/2013 | EP2554550A1 Method for inhibiting hiv replication in mammal and human cells |
01/23/2013 | CN101555221B Producing method of prostaglandin F-type derivant |
01/16/2013 | CN102884075A Method for inhibiting HIV replication in mammal and human cells |
01/16/2013 | CN102875586A Method for preparing key intermediate of limaprost |
01/02/2013 | CN101827598B Pharmaceutical combination of opioid and prostaglandin compound |
12/26/2012 | EP2536705A1 Polymorphic forms of lubiprostone |
12/12/2012 | CN102816100A Crystal form of prostaglandin analogue, and preparation method and application thereof |
12/12/2012 | CN102816099A High-purity carboprost tromethamine, and preparation method and application thereof |
12/06/2012 | WO2012164324A1 Novel processes for the preparation of prostaglandin amides |
12/06/2012 | CA2837261A1 Novel processes for the preparation of prostaglandin amides |
12/05/2012 | CN1893977B Remedies for diseases with bone mass loss having ep4 agonist as the active ingredient. |
11/28/2012 | CN101107225B 12-aryl prostaglandin analogs |
11/15/2012 | WO2011120474A8 Method for inhibiting hiv replication in mammal and human cells |
11/08/2012 | US20120283451 Process for the preparation of f-series prostaglandins |
11/01/2012 | WO2012146085A1 Intermediate for synthesizing prostaglandin medicines and preparation method therefor |
10/31/2012 | EP2516412A1 Processes for the purification of lubiprostone |