Patents
Patents for C07C 405 - Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins (3,702)
02/2015
02/18/2015EP2837621A1 Processes for the preparation of isomer free prostaglandins
02/17/2015US8957240 Method for the purification of prostaglandins
02/03/2015CA2847985C Process for stereoselective synthesis of prostacyclin derivatives
02/03/2015CA2589864C 12-aryl prostaglandin analogs
01/2015
01/29/2015US20150031898 Process for preparation of prostaglandin f2 alpha analogues
01/15/2015US20150018400 Treatment of inflammatory bowel disease
01/14/2015EP2822927A1 PROCESS FOR PREPARATION OF PROSTAGLANDIN F2alpha ANALOGUES
01/06/2015US8927280 Compositions and methods for promoting the generation of definitive endoderm
10/2014
10/21/2014US8865766 Ester derivatives of bimatoprost compositions and methods
09/2014
09/30/2014US8846958 Process for the preparation of lubiprostone
09/24/2014EP2781505A1 Positively charged water-soluble prodrugs of prostaglandins and related compounds with very high skin penetration rates
09/23/2014CA2628413C Prostaglandins and analogues as agents for lowering intraocular pressure
09/02/2014CA2549056C Prostaglandin synthesis
08/2014
08/21/2014US20140235665 Anti-constipation composition
07/2014
07/03/2014WO2014106204A1 Tromethamine salt of bimatoprost acid in crystalline form, methods for preparation, and methods for use thereof
06/2014
06/19/2014US20140171496 Composition and method for promoting hair growth
06/19/2014US20140171388 Compound for treating cartilage disorders
06/18/2014DE69331233C5 2-zykloalkyl-oder arylalkyl-derivate von nicht-säure, zyklopentane-heptanoic-säure 2-cycloalkyl or arylalkyl-derivatives of non-acid, heptanoic acid-zyklopentane
06/17/2014US8754122 Geminal dialkyl prostanoids
06/11/2014EP2740724A1 Compound for treating cartilage disorders
06/10/2014US8748657 Process to prepare treprostinil
06/05/2014WO2014083367A1 Process for the preparation of travoprost
06/03/2014CA2588056C 2,3,4-substituted cyclopentanones as therapeutic agents
05/2014
05/28/2014EP2735566A1 Method for preparing prostaglandin derivative
05/28/2014CN101379051B 用于制备前列腺素衍生物的方法 The method for preparing prostaglandin derivatives for
05/21/2014CN103813809A 聚合物缀合的前列腺素类似物 Polymer conjugated prostaglandin analogs
05/15/2014US20140135503 Novel processes for the preparation of prostaglandin amides
05/14/2014CN103787942A 一种制备鲁比前列酮的中间体、其制备方法以及通过其制备鲁比前列酮的方法 An intermediate lubiprostone preparation, preparation and a method for their preparation by lubiprostone in
05/07/2014CN102007098B 治疗性的取代的环戊烷 Treatment of a substituted cyclopentane
05/06/2014CA2307163C Process for stereoselective synthesis of prostacyclin derivatives
04/2014
04/30/2014EP2723714A1 Novel processes for the preparation of prostaglandin amides
04/30/2014CN102099330B Nitric oxide donating prostamides
04/01/2014US8686035 Composition and method for promoting hair growth
03/2014
03/26/2014CN103664726A Deuterated bimatoprost or derivative thereof and preparation method and application of deuterated bimatoprost or derivative thereof
03/25/2014US8680327 Methods for manufacturing tetranor-prostaglandin D, J, E, A and F metabolites
03/20/2014WO2014040457A1 Intermediate of limaprost, preparation method thereof and preparation method of limaprost therefrom
03/19/2014CN103649047A Novel processes for the preparation of prostaglandin amides
03/12/2014CN102050808B Preparation method for prostaglandin intermediate
02/2014
02/19/2014EP2696899A1 Polymer conjugated prostaglandin analogues
02/19/2014CN103588692A Method of purification of prostaglandins including fluorine atoms by preparative high performance liquid chromatography
02/13/2014WO2014023256A1 Process for preparation of tafluprost and intermediates thereof
02/12/2014CN103570599A Preparation method of prostaglandin A1
02/11/2014US8648213 Prostamides for the treatment of glaucoma and related diseases
01/2014
01/30/2014US20140031428 Method for treating schizophrenia
01/22/2014CN102336693B Carboprost tromethamine crystals, preparation method and application thereof
01/09/2014WO2012164324A9 Novel processes for the preparation of prostaglandin amides
12/2013
12/31/2013US8618086 Compositions and methods for treating hair loss using C16-C20 aromatic tetrahydro prostaglandins
12/25/2013EP2675786A1 Ester derivatives of bimatoprost compositions and methods
12/18/2013CN103459368A Ester derivatives of bimatoprost compositions and methods
12/05/2013US20130324606 Ester Derivatives of Bimatoprost Compositions and Methods
11/2013
11/07/2013WO2013164729A1 An improved and scalable process for preparation of prostaglandin derivatives and intermediates thereof
10/2013
10/30/2013CN103373947A Green synthesis method for dinoprostone (prostaglandin PGE2)
10/01/2013US8546114 Processes for the preparation of optically active cyclopentenones and cyclopentenones prepared therefrom
09/2013
09/25/2013CN103319390A Alprostadil compound and composition thereof
09/12/2013WO2013133730A1 PROCESS FOR PREPARATION OF PROSTAGLANDIN F2α ANALOGUES
09/11/2013CN103288698A Novel method for synthetizing prostaglandin analogue
09/10/2013US8530519 Method for promoting upper gastrointestinal bicarbonate secretion
09/04/2013CN101721708B ED-71 preparation
08/2013
08/21/2013EP2628725A1 Prostaglandins and analogues as agents for lowering intraocular pressure
08/21/2013CN102050772B Bimatoprost crystal as well as preparation method and purposes thereof
08/20/2013CA2515631C 10,10-dialkyl prostanoic acid derivatives as agents for lowering intraocular pressure
08/15/2013WO2013118058A1 Amine salts of prostaglandin analogs
08/13/2013US8507274 Compositions and methods for promoting the generation of definitive endoderm
08/08/2013US20130202704 Use of mexiprostil in the treatment of inflammatory bowel disease and/or of irritable bowel syndrome
08/06/2013US8501793 Blood flow promoters for cauda equina tissues
07/2013
07/18/2013WO2013104317A1 Crystal form of prostaglandin analogue, and preparation method and use thereof
07/03/2013CN101903324B Process to prepare treprostinil, the active ingredient in Remodulin
06/2013
06/27/2013WO2013093528A1 Process for the preparation of travoprost
06/12/2013CN102126998B Endothelin antagonist
06/12/2013CN101795692B Therapeutic substituted cyclopentanes for reducing intraocular pressure
06/04/2013US8455547 Substituted cyclopentanes having prostaglandin activity
05/2013
05/22/2013CN101921220B Pharmaceutical compositions for treating diseases with bone mass loss having EP4 agonist as the active ingredient
05/16/2013WO2013040068A3 Process for preparing synthetic prostacyclins
05/07/2013CA2534645C Composition and method for promoting hair growth
04/2013
04/24/2013CN103058907A Preparation method of lubiprostone or midbody thereof
04/24/2013CN101265226B Compounds and methods for delivery of prostacyclin analogs
04/17/2013EP2580192A2 Methods for manufacturing tetranor-prostaglandin d, j, e, a and f metabolites
04/17/2013CN102020625B High-purity lubiprostone, preparation method and application thereof
04/09/2013US8414904 Ophthalmic oil-in-water emulsions containing prostaglandins
03/2013
03/21/2013WO2013040068A2 Process for preparing synthetic prostacyclins
03/21/2013US20130072695 Prostaglandin synthesis and intermediates for use therein
03/06/2013CN102351767B Alprostadil compound and preparation method thereof
02/2013
02/14/2013WO2013021935A1 Compound for treating cartilage disorders
02/07/2013US20130035393 Method for treating schizophrenia
02/06/2013EP2554550A1 Method for inhibiting hiv replication in mammal and human cells
01/2013
01/23/2013CN101555221B Producing method of prostaglandin F-type derivant
01/16/2013CN102884075A Method for inhibiting HIV replication in mammal and human cells
01/16/2013CN102875586A Method for preparing key intermediate of limaprost
01/02/2013CN101827598B Pharmaceutical combination of opioid and prostaglandin compound
12/2012
12/26/2012EP2536705A1 Polymorphic forms of lubiprostone
12/12/2012CN102816100A Crystal form of prostaglandin analogue, and preparation method and application thereof
12/12/2012CN102816099A High-purity carboprost tromethamine, and preparation method and application thereof
12/06/2012WO2012164324A1 Novel processes for the preparation of prostaglandin amides
12/06/2012CA2837261A1 Novel processes for the preparation of prostaglandin amides
12/05/2012CN1893977B Remedies for diseases with bone mass loss having ep4 agonist as the active ingredient.
11/2012
11/28/2012CN101107225B 12-aryl prostaglandin analogs
11/15/2012WO2011120474A8 Method for inhibiting hiv replication in mammal and human cells
11/08/2012US20120283451 Process for the preparation of f-series prostaglandins
11/01/2012WO2012146085A1 Intermediate for synthesizing prostaglandin medicines and preparation method therefor
10/2012
10/31/2012EP2516412A1 Processes for the purification of lubiprostone
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