Patents for C07H 21 - Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids (89,892) |
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10/31/1990 | EP0394261A1 Novel thrombolytic proteins |
10/30/1990 | US4966964 Inhibitors of angiogenin |
10/27/1990 | CA2013800A1 Amplification of nucleic acid sequences using oligonucleotides of random sequence as primers |
10/24/1990 | EP0393744A1 Methods of extracting, amplifying and detecting a nucleic acid from PBMC blood fraction |
10/24/1990 | EP0393502A1 Soluble interferon-gamma receptors and methods for their production |
10/24/1990 | EP0393431A1 Homologues of Alzheimer protease inhibitor prepared genetechnologically, host-strains and expression vectors for their preparation and use as a medicament |
10/23/1990 | US4965350 Fluorescent detectors |
10/23/1990 | US4965349 Hydrolysis of linking group with mixture of alcohol, water, and hindered amine |
10/23/1990 | US4965190 Methods for the identification of mutations in the human phenylalanine hydroxylase gene using DNA probes |
10/21/1990 | CA2014990A1 Method of inhibiting induction of latent or chronic viral infection |
10/19/1990 | WO1990012802A1 Novel oligodeoxynucleotides with 5'-linked chemical groups, method of production thereof and use thereof |
10/19/1990 | CA2049361A1 Oligodeoxynucleotides with 5'-linked chemical groups, method of product thereof and use thereof |
10/19/1990 | CA2014752A1 Soluble interferon-gamma receptors and methods for their production |
10/18/1990 | WO1990012096A1 Method for enhancing transmembrane transport of exogenous molecules |
10/18/1990 | WO1990012024A1 Method of synthesizing oligonucleotides adaptable to large scale syntheses |
10/18/1990 | WO1990012022A1 Polynucleotide phosphorodithioates as therapeutic agents for retroviral infections |
10/18/1990 | WO1990012020A1 Coumarin derivatives for use as nucleotide crosslinking reagents |
10/18/1990 | WO1990008828A3 Molecular methods of hybrid seed production |
10/18/1990 | DE3905448C1 Process for the synthesis of macromolecules of specific chain length, structure and sequence |
10/18/1990 | CA2051692A1 Method of synthesizing oligonucleotides adaptable for large scale syntheses |
10/18/1990 | CA2014855A1 Amplified nucleic acid hybridization assays for hbv |
10/17/1990 | EP0392546A2 Process for determination of a complete or a partial contents of very short sequences in the samples of nucleic acids connected to the discrete particles of microscopic size by hybridization with oligonucleotide probes |
10/17/1990 | EP0391957A1 A METHOD OF SIMULTANEOUSLY PRODUCING A LARGE NUMBER OF Leu?17 -VIP-ANALOGS AND NEW Leu?17 -VIP-ANALOGS |
10/17/1990 | CA2013316A1 Methods of extracting, amplifying and detecting a nucleic acid from whole blood or pbmc fraction |
10/16/1990 | US4963532 dsRNA-based prevention of viral escape |
10/16/1990 | US4963477 Probe containing a modified nucleic acid, recognizable by specific antibodies and use of this probe and theses specific antibodies to detect and characterize a homologous DNA sequence |
10/10/1990 | EP0391039A1 A DNA probe for Lactobacillus delbrueckii |
10/10/1990 | EP0391022A2 Signal peptide for the secretion of peptides in Escherichia coli, method for obtaining it and its use |
10/10/1990 | EP0390910A1 Hapten derivatized captured membran and diagnostic assays using such membrane. |
10/09/1990 | US4962029 Covalent oligonucleotide-horseradish peroxidase conjugate |
10/04/1990 | WO1990011322A2 Method and reagent for sulfurization of organophosphorous compounds |
10/04/1990 | WO1990011092A1 Expression of exogenous polynucleotide sequences in a vertebrate |
10/04/1990 | WO1990011089A1 Nanbv diagnostics and vaccines |
10/04/1990 | DE3910151A1 5'-Bromo-2'-deoxyuridine-labelled DNA or RNA probes |
10/04/1990 | CA2489769A1 Expression of exogenous polynucleotide sequences in a vertebrate |
10/04/1990 | CA2357538A1 Expression of exogenous polynucleotide sequences in a vertebrate |
10/03/1990 | EP0390518A2 Novel compositions and protocols applicable to genetic analysis |
10/03/1990 | EP0389521A1 2',5'-phosphorothioate oligoadenylates and antiviral uses thereof |
10/03/1990 | CA2013580A1 Method for enhancing transmembrane transport of exogenous molecules |
10/02/1990 | US4960700 Compositions and methods for the synthesis and assay of a mammalian enkephalinase |
09/26/1990 | EP0389066A1 Inhibition resistant 5-enolpyruvyl-3-phosphoshikimate synthetase and plant materials containing it |
09/26/1990 | EP0389063A2 Process for isolating nucleic acid |
09/26/1990 | EP0389034A1 Hog cholera virus vaccine and diagnostic |
09/25/1990 | US4959463 Coupling ribonucleotides or deoxyribonucleotides though phosphonate groups |
09/25/1990 | US4959353 Promotion of corneal stroma wound healing with human epidermal growth factor prepared from recombinant DNA |
09/25/1990 | US4959309 Fast photochemical method of labelling nucleic acids for detection purposes in hybridization assays |
09/23/1990 | CA2271603A1 Process for isolating nucleic acid |
09/20/1990 | WO1990010699A1 MOLECULAR CLONING OF GENOMIC AND cDNA SEQUENCES ENCODING CELLULAR RECEPTORS FOR POLIOVIRUS |
09/20/1990 | WO1990010637A1 Method for purifying nucleic acids |
09/19/1990 | EP0388232A1 NANBV diagnostics and vaccines |
09/19/1990 | EP0388171A2 Methods for purification, amplification and detection of a nucleic acid |
09/19/1990 | EP0387915A1 F antigens of the human immunodeficiency virus, and their applications |
09/19/1990 | EP0387914A1 Envelope antigens of the human immuno-deficiency virus, and their applications |
09/19/1990 | EP0387775A1 Genetic construct for inhibiting RNA function |
09/19/1990 | EP0387668A1 Intercellular adhesion molecule - 2 and its binding ligands |
09/19/1990 | EP0387452A2 Method of preparing nucleotide probes using a hybridizable complementary element |
09/18/1990 | WO1990011367A1 IMMUNOGLOBULIN A1 PROTEASES (IgA1 PROTEASES), METHOD OF GENE-TECHNOLOGICALLY PRODUCING THIS TYPE OF ENZYME AND VACCINES CONTAINING THE ENZYMES AND FRAGMENTS THEREOF FOR IMMUNIZING AGAINST BACTERIAL MENINGITIS AND OTHER DISEASES CAUSED BY IgA1 PROTEASE-PRODUCING BACTERIA |
09/18/1990 | US4958013 Cholesteryl modified oligonucleotides |
09/18/1990 | US4957858 Replicative RNA reporter systems |
09/18/1990 | CA2049984A1 Immunoglobulin al proteases (iga1 proteases), method of gene-technologically producing this type of enzyme and vaccines containing the enzymes and fragments thereof for immunizingagainst bacterial meningitis and other diseases caused by iga1 protease-producing bacteria |
09/17/1990 | CA2483289A1 Hepatitis c diagnostics and vaccines |
09/17/1990 | CA2011818A1 Methods for purification, amplification and detection of a nucleic acid |
09/15/1990 | WO1990010713A1 Method for stabilizing the hybridization of complementary polynucleotide sequences |
09/15/1990 | CA2050913A1 Complementary base sequence hybridization stabilization process |
09/12/1990 | EP0386987A1 Method and reagent for sulfurization of organophosphorous compounds |
09/12/1990 | EP0386563A1 Antisense-oligonucleotides for inhibiting the transactivator target sequence (TAR) and the synthesis of the transactivator protein (Tat) of HIV-I, and their use |
09/12/1990 | EP0386229A1 Support-bound oligonucleotides. |
09/12/1990 | EP0386228A1 Replicative rna-based amplification/detection systems. |
09/11/1990 | US4956281 DNA sequences, recombinant DNA molecules and processes for producing lymphocyte function associated antigen-3 |
09/11/1990 | CA2048993A1 Molecular cloning of genomic and cdna sequences encoding cellular receptors for poliovirus |
09/11/1990 | CA1273862A1 Reagents and kits for quantitation of a viral nucleic acid in a biological medium and quantitation process of such viral nucleic acid |
09/08/1990 | WO1990010448A2 Covalent conjugates of lipid and oligonucleotide |
09/08/1990 | CA2049028A1 Covalent conjugates of lipid and oligonucleotide |
09/07/1990 | WO1990010649A1 Serpin resistant chymotrypsin superfamily proteases, particularly pai-1 resistant +-pa, complementary inhibitor mutants; compositions; genes; expression |
09/07/1990 | WO1990010067A1 Dna sequences coding for pth variants, pth variants, expression vector, bacterial host, use and therapeutic composition |
09/07/1990 | WO1990010013A1 TYPE oc PLATELET-DERIVED GROWTH FACTOR RECEPTOR GENE |
09/07/1990 | WO1990010011A1 Use of 2-tert.-alkylimino-2-di-c1-4-alkylamino-1,3-di-c1-3-alkylperhydro-1,3,2-diazaphosphorine for o-substitution reactions of ribonucleosides |
09/07/1990 | WO1990009802A1 Human intra-acrosomal sperm antigen for use in a contraceptive vaccine |
09/07/1990 | WO1990009737A1 Human elastase inhibitor |
09/06/1990 | DE3915462A1 Verwendung von 2-tert.-alkylimino-2-di-c(pfeil abwaerts)1(pfeil abwaerts)(pfeil abwaerts)-(pfeil abwaerts)(pfeil abwaerts)4(pfeil abwaerts)-alkylamino- 1,3-di-c(pfeil abwaerts)1(pfeil abwaerts)(pfeil abwaerts)-(pfeil abwaerts)(pfeil abwaerts)3(pfeil abwaerts)-alkyl-perhydro-1,3,2-diazaphosphorin fuer 0-substituierungsreaktionen von ribonukleosiden Use of 2-tert-alkylimino-2-di-c (down arrow) 1 (arrow down) (Down Arrow) - (arrow down) (Down Arrow) 4 (down arrow) alkylamino 1,3-di- c (Down Arrow) 1 (arrow down) (Down Arrow) - (arrow down) (Down Arrow) 3 (down arrow) alkyl-perhydro-1,3,2-diazaphosphorine for 0-substituierungsreaktionen of ribonucleosides |
09/05/1990 | EP0385558A2 Materials and methods for genome walking |
09/04/1990 | WO1990010075A1 Yeast processing system comprising a negatively charged amino acid adjacent to the processing site |
09/04/1990 | CA1273590A1 Messenger rna, production and use thereof |
09/04/1990 | CA1273589A1 Carriers, process for their preparation and the intermediates obtained, use in the synthesis of oligonucleotides linked to such carriers |
09/02/1990 | WO1990010228A1 Matrix metalloproteinase peptides: role in diagnosis and therapy |
08/29/1990 | EP0384122A2 Mutants of human antithrombin III |
08/29/1990 | EP0383803A1 Oligonucleotide-polyamide conjugates |
08/28/1990 | US4952674 Dna segment endcoding the immunogenic glycoprotein |
08/28/1990 | US4952512 Gene encoding an inhibitor of tissue-type and urokinase-type plasminogen activators |
08/25/1990 | WO1990009786A1 Heterologous block oligomers |
08/25/1990 | CA2028153A1 Heterologous block oligomers |
08/23/1990 | WO1990009393A1 Method of separating oligonucleotides from a mixture |
08/23/1990 | WO1990009180A1 Methods and compositions for treatment of cancer using oligonucleotides |
08/22/1990 | EP0383620A2 Process for making genes encoding random polymers of amino acids |
08/21/1990 | US4950745 Used in genetic engineering |
08/21/1990 | US4950652 Aids and aids-related complex |
08/21/1990 | US4950602 Analogs of nicotinamide-adenine-dinucleotide |
08/17/1990 | CA2009996A1 Process for making genes encoding random polymers of amino acids |
08/16/1990 | EP0224578B1 Compositions and methods for functionalizing nucleic acids |
08/14/1990 | US4948882 Single-stranded labelled oligonucleotides, reactive monomers and methods of synthesis |