Patents
Patents for C07H 21 - Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids (89,892)
10/1991
10/23/1991EP0452420A1 End-attachment of oligonucleotides to polyacrylamide solid supports for capture and detection of nucleic acids
10/22/1991US5059538 Recombinant plasmid inserted with herpes simplex virus gene
10/17/1991WO1991015500A1 Oligonucleotide analogs
10/17/1991WO1991015234A1 Recombinant bile salt activated lipases
10/17/1991WO1991013075A3 Method and reagent for determining specific nucleotide variations
10/16/1991EP0451878A1 Modifying plants by genetic engineering to combat or control insects
10/15/1991US5057426 Method for separating long-chain nucleic acids
10/15/1991US5057412 Cleaving pyrimidine rionucleoside diester producing coeneyme for further reaction
10/15/1991CA1290664C Solution-phase single hybridization assay for detecting polynucleotide sequences
10/10/1991WO1991015499A1 2'-o-alkyl nucleotides and polymers containing them
10/10/1991DE4037363A1 New 2-O-alkyl nucleotide(s) and polymers contg. them - for nuclease-resistant anti-sense probes and to treat viral infection including herpes influenza and AIDS and cancer
10/09/1991EP0450370A1 Branch migration of nucleotides
10/09/1991EP0450060A1 Dna sequencing
10/09/1991EP0450048A1 Stable mammalian cell lines that express aromatase
10/09/1991EP0449980A1 Sequential peptide and oligonucleotide synthesis using immunoaffinity techniques
10/09/1991EP0449972A1 Triple stranded nucleic acid and methods of use
10/09/1991EP0449968A1 PROCESS FOR THE PREPARATION OF HUMAN DNase
10/09/1991EP0414809A4 Plant defense gene regulatory elements
10/08/1991US5055393 Labeled oligonucleotides capable of hybridizing with male specific sequences
10/08/1991US5055392 Cloning of dna encoding transcription factor s-11
10/08/1991CA1290481C Graft copolymers of crosslinked polymers and polyoxyethylene, processes for their production, and their usage
10/08/1991CA1290267C Human anti-inflammatory phospholipase inhibitor protein
10/07/1991CA2039814A1 Species determination of spruce seedlots using dna restriction fragment length polymorphism
10/02/1991EP0448667A1 A dna fragment encoding a rubber polymerase and its related products
10/02/1991EP0448609A1 In vitro mutagenesis.
10/01/1991US5053326 Hybridization method and probe
10/01/1991CA1289901C Vector with multiple promoters
09/1991
09/30/1991WO1991014696A1 Oligonucleotide-transport agent disulfide conjugates
09/30/1991CA2079109A1 Oligonucleotide-transport agent disulfide conjugates
09/25/1991EP0447442A1 Method for polymerase activity determination.
09/22/1991WO1991014436A1 Reagents and methods for modulating gene expression through rna mimicry
09/22/1991CA2078659A1 Reagents and methods for modulating gene expression through rna mimicry
09/19/1991WO1991013902A2 Site-specific functionalization of oligodeoxynucleotides for non-radioactive labelling
09/19/1991WO1991013897A1 Multichromophore fluorescent probes
09/18/1991EP0446931A1 Human ciliary neuronotrophic factor, DNA sequence encoding the factor, and production of the factor by recombinant technology
09/18/1991EP0446245A1 Electrochemiluminescent assays
09/18/1991CN1054616A Dna fragment encoding polypeptide having nitrile hydratase activity, transformant containing gene and process for production amides using transformant
09/17/1991US5049656 Capping
09/17/1991US5049488 Method and nucleic acid for the preparation of lecithin:cholesterol acyltransferase
09/15/1991CA2038208A1 Process for the isolation and expression of the human ciliary neuronotrophic factor by recombinant dna technology
09/11/1991EP0445681A2 Preparation of a thrombin-binding substance
09/11/1991EP0445646A2 DNA fragment encoding a polypeptide having nitrile hydratase activity, a transformant containing the DNA fragment and a process for the production of amides using the transformant
09/11/1991EP0188479B1 Lymphokine production and purification
09/10/1991US5047524 Solid phase syntheisis o nonsuelladle porous polystyrene support by phosphoramide or hydrogen phosphonate chemistry
09/10/1991US5047523 Nucleic acid probe for detection of neisseria gonorrhoea
09/10/1991US5047519 Chain Terminating Substrates For DNA Sequencing
09/10/1991US5047345 Composition for isolating and purifying nucleic acid and improved method using same
09/10/1991US5047336 DNA sequences, recombinant DNA molecules and processes for producing mullerian inhibiting substance-like polypeptides
09/10/1991US5047334 To produce proteins consisting of specific dna system
09/10/1991CA1288709C Immobilization of nucleic acids on derivatized nylon supports
09/10/1991CA1288708C Immobilization of nucleic acids on solvolyzed nylon supports
09/07/1991CA2037499A1 Preparation of a thrombin-binding substance
09/05/1991WO1991013080A1 Pseudonucleosides and pseudonucleotides and their polymers
09/05/1991WO1991013077A1 Calcium channel compositions and methods
09/05/1991WO1991013075A2 Method and reagent for determining specific nucleotide variations
09/05/1991WO1991012811A1 Oligonucleotide therapies for modulating the effects of herpesviruses
09/05/1991CA2074523A1 Oligonucleotide therapies for modulating the effects of herpesviruses
09/04/1991EP0444119A1 PROCESS FOR PRODUCING cDNA.
09/04/1991EP0263155B1 A process for obtaining chemically defined and reproducible polydeoxyribonucleotides
09/03/1991WO1991013090A1 Improved chimeric toxins
09/03/1991CA1288363C Process and apparatus for the purification of synthetic oligonucleotides
08/1991
08/28/1991EP0298982B1 Protecting groups for organic synthesis
08/28/1991EP0256055B1 Recombinant dna sequences, vectors containing them and method for the use thereof
08/28/1991EP0198015B1 Production of streptavidin-like polypeptides
08/27/1991US5043272 Amplification of nucleic acid sequences using oligonucleotides of random sequence as primers
08/27/1991US5043271 DNA encoding rabbit TNE, vector having said DNA inserted thereinto, host transformed with said vector, rabbit TNF polypeptide, and process for production thereof
08/22/1991WO1991012258A1 Retinoid receptor compositions and methods
08/21/1991EP0441991A1 A DNA probe for Lactobacillus helveticus
08/21/1991EP0365657A4 Dna encoding androgen receptor protein
08/14/1991EP0441763A2 Heparin-binding growth factor
08/14/1991EP0441252A2 Alkaline phosphatase enzymes having improved specific activity for use in indicator reagents
08/14/1991EP0440647A1 Labeled nucleic acid probe
08/14/1991DE4003880A1 Synthetic human antibody library
08/13/1991US5039796 Using phosphoramine compound
08/13/1991US5038852 Apparatus and method for performing automated amplification of nucleic acid sequences and assays using heating and cooling steps
08/08/1991WO1991011535A1 Inhibition of transcription by double-stranded oligonucleotides
08/08/1991DE4002897A1 Synthetic human antibody library
08/08/1991CA2035826A1 Alkaline phosphatase enzymes having improved specific activity for use in indicator reagents
08/07/1991EP0440146A2 Preparation and use of synthetic human antibody gene bank (synthetic human antibody libraries)
08/07/1991EP0143849B1 Process and apparatus for scission treatment of deoxyribonucleic acid
08/07/1991CN1053642A 传染性支气管炎病毒疫苗 Infectious bronchitis virus vaccine
08/06/1991US5037806 Biologically active method using somatotropins
08/06/1991US5037751 Ability for stereoselective hydrolysis of naproxen ester; gene encoded enzyme
08/06/1991CA1287311C Recombinant dna provided with hepatitis b virus gene, mammalian cells transformed with cloned viral dna, and production of hepatitis b virus proteins
07/1991
07/31/1991EP0439182A2 Improved method of amplifying target nucleic acids applicable to both polymerase and ligase chain reactions
07/31/1991EP0439036A2 Energy transferring system
07/31/1991EP0175776B1 Hybridization histochemistry
07/31/1991CN1053446A Production of recombinant polypeptides by bovine species and transgenic methods
07/31/1991CN1053360A Diagnosis and treatment of neuro-cognitive disorders associated with systemic immunological malfuction
07/30/1991US5035998 Hydrolase substrates
07/30/1991US5035996 Process for controlling contamination of nucleic acid amplification reactions
07/26/1991CA2033692A1 Energy transfer systems
07/25/1991WO1991010746A1 Dna-dependent rna polymerase transcripts as reporter molecules for signal amplification in nucleic acid hybridization assays
07/25/1991WO1991010682A1 Proteins produced by human lymphocytes, dna sequence coding these proteins, and pharmaceutical and biological uses thereof
07/25/1991WO1991010675A1 Primers and process for detecting human papillomavirus genotypes by pcr
07/25/1991WO1991010671A1 Compositions and methods for detecting and modulating rna activity and gene expression
07/25/1991WO1991010426A1 Conjugates of biologically stable polymers and polynucleotides for treating systemic lupus erythematosus
07/25/1991CA2070632A1 Use of dna-dependent rna polymerase transcripts as reporter molecules for signal amplification in nucleic acid hybridization assays
07/24/1991EP0438259A1 Conjugates of biologically stable polymers and polynucleotides for treating systemic lupus erythematosus
07/24/1991EP0438203A2 Nucleoside derivatives and their use in oligonucleotide synthesis