Patents for C07H 21 - Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids (89,892) |
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10/12/1988 | EP0285950A2 A drug delivery conjugate |
10/12/1988 | EP0149634B1 Process for the definite cross-linking of double helix dna fragments by means of a linkage dna as well as oligonucleotides used as linkage dna |
10/11/1988 | US4777270 Macrocyclic polyether carboxylic acids |
10/06/1988 | WO1988007581A1 Novel proteolytic enzymes |
10/06/1988 | WO1988007544A1 Inhibitors for replication of retroviruses and for the expression of oncogene products |
10/06/1988 | WO1988007543A1 Human tissue factor related dna segments, polypeptides and antibodies |
10/06/1988 | WO1988007542A1 Poly(deoxyribonucleotides), pharmaceutical compositions, use and preparation of the poly(deoxyribonucleotides) |
10/05/1988 | EP0285263A2 Activated RNase L as a marker for virus infections |
10/05/1988 | EP0285058A2 Modified labeled nucleotides and polynucleotides and methods of preparing, utilizing and detecting same |
10/05/1988 | EP0285057A2 Modified labeled nucleotides and polynucleotides and methods of preparing, utilizing and detecting same |
10/04/1988 | US4775624 Constructed dna; cardiovascular disorders |
10/04/1988 | US4775622 Expression, processing and secretion of heterologous protein by yeast |
10/04/1988 | CA1242701A1 Means for sequential solid phase organic synthesis and methods using the same |
10/04/1988 | CA1242657A1 Derivatised nucleic acid sequences |
10/04/1988 | CA1242627A1 Method for detection of polymorphic restriction sites and nucleic acid sequences |
09/28/1988 | EP0284362A2 Molecular markers |
09/28/1988 | EP0268636A4 Fc receptor for immunoglobulin. |
09/28/1988 | EP0222889A4 Cytidine analogs. |
09/28/1988 | EP0158758B1 Probe containing a modified nucleic acid recognizable by specific antibodies and the use to detect and characterize a homologous dna sequence |
09/27/1988 | US4774180 Genetic engineering, dna sequence |
09/21/1988 | EP0283327A2 Peptides with the immunological properties of HIV-2 |
09/21/1988 | EP0282899A2 Human manganese superoxide dismutase (hMn-SoD) |
09/21/1988 | EP0282733A2 Method of enumerating escherichia coli |
09/20/1988 | US4772691 Chemically cleavable nucleotides |
09/20/1988 | US4772594 Prodrug compounds, process for the preparation thereof and sustained release preparation comprising the same |
09/14/1988 | EP0281673A1 Plasmid for production of membrane protein, bacterium containing same, monoclonal antibody therefore, and method for the identification of haemophilus influenzae |
09/14/1988 | EP0104217B1 Coding dna fragments for polypeptides containing at least one antigenic determinant of the papillomavirus particularly of the la hpv type and corresponding polypeptides |
09/07/1988 | WO1988006634A1 A method of detection of carcinogenic human papillomavirus |
09/07/1988 | WO1988006633A1 Polycationic supports for nucleic acid purification, separation and hybridization |
09/07/1988 | EP0281390A2 Polycationic supports for nucleic acid purification, separation and hybridization |
09/07/1988 | EP0281069A1 Production of human granulocyte-macrophage colony stimulating factor |
09/06/1988 | US4769239 Vaccine against varicella-zoster virus |
08/31/1988 | EP0280407A2 Process for the production of recombinant polypeptides with porcine growth hormone activity |
08/30/1988 | US4767701 Poly I:C covalently bonded to polymer for diagnostic purposes |
08/30/1988 | US4767670 Chromatographic supports for separation of oligonucleotides |
08/25/1988 | WO1988006186A2 cDNAs ENCODING SOMATOTROPIN, EXPRESSION VECTORS AND HOSTS |
08/24/1988 | EP0279582A2 DNA sequences to target proteins to the mammary gland for efficient secretion |
08/23/1988 | EP0215942A4 Polynucleotide assay reagent and method. |
08/23/1988 | CA1240990A1 Heptaose compounds |
08/23/1988 | CA1240986A1 Tricyclic antidepressant drug immunogens, antibodies, labeled conjugates, and related derivatives |
08/23/1988 | CA1240940A1 A-factor and its processing signals |
08/17/1988 | EP0278776A2 Methods and deoxyribonucleic acid for the preparation of tissue factor protein |
08/17/1988 | EP0278513A2 Process of preparing single-stranded DNA |
08/17/1988 | CN87108308A Polypeptides and production thereof |
08/16/1988 | US4764593 Manufacture and expression of genes for urogastrone and polypeptide analogs thereof |
08/16/1988 | CA1240629A1 Deoxyribonucleic acid molecules useful as probes for detecting deleterious genes incorporated into chromosomal dna |
08/11/1988 | WO1988003807A3 Production and use of a novel t-cell suppressor factor |
08/10/1988 | EP0277212A1 Diagnostic assay for inhibitor of tissue-type and urokinase-type plasminogen activators, and gene coding for the inhibitor. |
08/10/1988 | EP0135532B1 Method of producing and selectively isolating proteins and polypeptides, recombinant and expression vector therefor and fusion protein able to bind to the constant region of immunoglobulins |
08/10/1988 | CN88100542A Precursor protein of apc polypeptide, dna coding for this, and diagnostic use of dna and of protein |
08/09/1988 | US4762791 Human immune interferon |
08/09/1988 | US4762779 Labeling by bonding a phosphoramidite of a hydroxylamine |
08/03/1988 | EP0276723A2 Precursor protein of APC polypeptide, DNA coding therefor and diagnostic use of the DNA and protein |
08/03/1988 | EP0276330A1 Recombinant plasmid dnas, coding for synthesis of polypeptide substances for a vaccine against hepatitis a |
08/02/1988 | US4761371 Genetic engineering |
07/28/1988 | WO1988005440A1 Peptides having immunological properties 2-hiv-2 |
07/28/1988 | WO1988005300A1 Antiviral agent |
07/27/1988 | EP0276138A2 Chromatographic supports for separation of oligonucleotides |
07/27/1988 | EP0275856A1 New plasminogen activators |
07/27/1988 | EP0275689A1 Modified pertussis exotoxin |
07/27/1988 | EP0275305A1 Dna sequences coding for modified factor viii:c and modified factor viii:c-like polypeptides and processes for producing these polypeptides in high yields |
07/26/1988 | US4760023 Complimentary strand of polydeoxyribonucleotide |
07/26/1988 | US4760017 Arabinonucleic acid probes for DNA/RNA assays |
07/20/1988 | EP0274700A1 Substrates for hydrolases |
07/19/1988 | US4758516 Molecular cloning and characterization of a further gene sequence coding for human relaxin |
07/19/1988 | US4758507 Products displaying the antigenicity of hepatitis B virus e antigens and methods of producing those antigens |
07/14/1988 | WO1988005074A1 Porous wafer for segmented synthesis of biopolymers |
07/14/1988 | WO1988004932A1 Vaccines and diagnostic assays for haemophilus influenzae |
07/14/1988 | WO1988002406A3 Methods of regulating metabolic stability of proteins |
07/12/1988 | US4757141 Conjugates with oligonucleotides |
07/12/1988 | US4757055 Binding herpes virus with nonionic oligonucleoside alkyl or arylphosphonate complementary to base sequence of virus |
07/06/1988 | EP0273373A2 Novel peptides and production thereof |
07/06/1988 | EP0273115A2 Chemiluminescent acridinium and phenanthridinium salts |
07/05/1988 | US4755363 Alternatively employing batch-wise, vapor diffusion or free interface diffusion procedures |
06/30/1988 | WO1988004690A1 New plasminogen activators |
06/30/1988 | WO1988004689A1 Primary biliary cirrhosis autoantigen |
06/29/1988 | EP0272928A2 Compositions and methods for the synthesis and assay of enkephalinase |
06/29/1988 | EP0272321A1 A DNA SEQUENCE ENCODING THE $i(MAS) ONCOGENE, POLYPEPTIDES ENCODED THEREFROM, AND DIAGNOSTIC AND OTHER METHODS BASED THEREON |
06/28/1988 | US4754065 Precursor to nucleic acid probe |
06/28/1988 | US4753985 Oligopeptides recovered from a synthesizing gel |
06/28/1988 | US4753795 Modified (80-113) beta interferons |
06/28/1988 | CA1238591A1 Recombinant dna cosmid shuttle vectors |
06/21/1988 | CA1238277A1 Antiviral nucleosides |
06/16/1988 | WO1988004324A1 Pulmonary hydrophobic surfactant-associated proteins |
06/16/1988 | WO1988004301A1 alpha OLIGONUCLEOTIDES |
06/16/1988 | WO1988004300A1 Rna ribozyme polymerases, dephosphorylases, restriction endoribonucleases and methods |
06/15/1988 | EP0270946A2 Chromogenic acridinone enzyme substrates |
06/15/1988 | EP0270651A1 Novel deoxyribonucleoside phosphoramidites and their use for the preparation of oligonucleotides. |
06/15/1988 | EP0270611A1 TRANSLATION OF mRNA. |
06/14/1988 | US4751313 Nonradioactive labeling |
06/08/1988 | EP0270017A2 Method of isolating and purifying nucleic acids from biological samples |
06/08/1988 | EP0269677A1 ASSAYS AND ANTIBODIES FOR N-$i(myc) PROTEINS |
06/08/1988 | EP0124562B1 Process for the production of oligonucleotides |
06/08/1988 | CN87108073A Detection of htlvi and htlvii viruses by hybridization |
06/07/1988 | US4749650 Guanosine, xanthosine production |
06/07/1988 | CA1237685A1 Process for amplifying nucleic acid sequences |
06/02/1988 | WO1988003926A1 Enhancing gamma-carboxylation of recombinant vitamin k-dependent proteins |
06/02/1988 | WO1988003807A2 Production and use of a novel t-cell suppressor factor |
06/01/1988 | EP0269445A2 Process for detecting HTLVI and HTLVII viruses by hybridization |
06/01/1988 | EP0269072A2 Cloning of DNA encoding human gip precursor and expression of the precursor |