Patents
Patents for C07H 21 - Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids (89,892)
10/1988
10/12/1988EP0285950A2 A drug delivery conjugate
10/12/1988EP0149634B1 Process for the definite cross-linking of double helix dna fragments by means of a linkage dna as well as oligonucleotides used as linkage dna
10/11/1988US4777270 Macrocyclic polyether carboxylic acids
10/06/1988WO1988007581A1 Novel proteolytic enzymes
10/06/1988WO1988007544A1 Inhibitors for replication of retroviruses and for the expression of oncogene products
10/06/1988WO1988007543A1 Human tissue factor related dna segments, polypeptides and antibodies
10/06/1988WO1988007542A1 Poly(deoxyribonucleotides), pharmaceutical compositions, use and preparation of the poly(deoxyribonucleotides)
10/05/1988EP0285263A2 Activated RNase L as a marker for virus infections
10/05/1988EP0285058A2 Modified labeled nucleotides and polynucleotides and methods of preparing, utilizing and detecting same
10/05/1988EP0285057A2 Modified labeled nucleotides and polynucleotides and methods of preparing, utilizing and detecting same
10/04/1988US4775624 Constructed dna; cardiovascular disorders
10/04/1988US4775622 Expression, processing and secretion of heterologous protein by yeast
10/04/1988CA1242701A1 Means for sequential solid phase organic synthesis and methods using the same
10/04/1988CA1242657A1 Derivatised nucleic acid sequences
10/04/1988CA1242627A1 Method for detection of polymorphic restriction sites and nucleic acid sequences
09/1988
09/28/1988EP0284362A2 Molecular markers
09/28/1988EP0268636A4 Fc receptor for immunoglobulin.
09/28/1988EP0222889A4 Cytidine analogs.
09/28/1988EP0158758B1 Probe containing a modified nucleic acid recognizable by specific antibodies and the use to detect and characterize a homologous dna sequence
09/27/1988US4774180 Genetic engineering, dna sequence
09/21/1988EP0283327A2 Peptides with the immunological properties of HIV-2
09/21/1988EP0282899A2 Human manganese superoxide dismutase (hMn-SoD)
09/21/1988EP0282733A2 Method of enumerating escherichia coli
09/20/1988US4772691 Chemically cleavable nucleotides
09/20/1988US4772594 Prodrug compounds, process for the preparation thereof and sustained release preparation comprising the same
09/14/1988EP0281673A1 Plasmid for production of membrane protein, bacterium containing same, monoclonal antibody therefore, and method for the identification of haemophilus influenzae
09/14/1988EP0104217B1 Coding dna fragments for polypeptides containing at least one antigenic determinant of the papillomavirus particularly of the la hpv type and corresponding polypeptides
09/07/1988WO1988006634A1 A method of detection of carcinogenic human papillomavirus
09/07/1988WO1988006633A1 Polycationic supports for nucleic acid purification, separation and hybridization
09/07/1988EP0281390A2 Polycationic supports for nucleic acid purification, separation and hybridization
09/07/1988EP0281069A1 Production of human granulocyte-macrophage colony stimulating factor
09/06/1988US4769239 Vaccine against varicella-zoster virus
08/1988
08/31/1988EP0280407A2 Process for the production of recombinant polypeptides with porcine growth hormone activity
08/30/1988US4767701 Poly I:C covalently bonded to polymer for diagnostic purposes
08/30/1988US4767670 Chromatographic supports for separation of oligonucleotides
08/25/1988WO1988006186A2 cDNAs ENCODING SOMATOTROPIN, EXPRESSION VECTORS AND HOSTS
08/24/1988EP0279582A2 DNA sequences to target proteins to the mammary gland for efficient secretion
08/23/1988EP0215942A4 Polynucleotide assay reagent and method.
08/23/1988CA1240990A1 Heptaose compounds
08/23/1988CA1240986A1 Tricyclic antidepressant drug immunogens, antibodies, labeled conjugates, and related derivatives
08/23/1988CA1240940A1 A-factor and its processing signals
08/17/1988EP0278776A2 Methods and deoxyribonucleic acid for the preparation of tissue factor protein
08/17/1988EP0278513A2 Process of preparing single-stranded DNA
08/17/1988CN87108308A Polypeptides and production thereof
08/16/1988US4764593 Manufacture and expression of genes for urogastrone and polypeptide analogs thereof
08/16/1988CA1240629A1 Deoxyribonucleic acid molecules useful as probes for detecting deleterious genes incorporated into chromosomal dna
08/11/1988WO1988003807A3 Production and use of a novel t-cell suppressor factor
08/10/1988EP0277212A1 Diagnostic assay for inhibitor of tissue-type and urokinase-type plasminogen activators, and gene coding for the inhibitor.
08/10/1988EP0135532B1 Method of producing and selectively isolating proteins and polypeptides, recombinant and expression vector therefor and fusion protein able to bind to the constant region of immunoglobulins
08/10/1988CN88100542A Precursor protein of apc polypeptide, dna coding for this, and diagnostic use of dna and of protein
08/09/1988US4762791 Human immune interferon
08/09/1988US4762779 Labeling by bonding a phosphoramidite of a hydroxylamine
08/03/1988EP0276723A2 Precursor protein of APC polypeptide, DNA coding therefor and diagnostic use of the DNA and protein
08/03/1988EP0276330A1 Recombinant plasmid dnas, coding for synthesis of polypeptide substances for a vaccine against hepatitis a
08/02/1988US4761371 Genetic engineering
07/1988
07/28/1988WO1988005440A1 Peptides having immunological properties 2-hiv-2
07/28/1988WO1988005300A1 Antiviral agent
07/27/1988EP0276138A2 Chromatographic supports for separation of oligonucleotides
07/27/1988EP0275856A1 New plasminogen activators
07/27/1988EP0275689A1 Modified pertussis exotoxin
07/27/1988EP0275305A1 Dna sequences coding for modified factor viii:c and modified factor viii:c-like polypeptides and processes for producing these polypeptides in high yields
07/26/1988US4760023 Complimentary strand of polydeoxyribonucleotide
07/26/1988US4760017 Arabinonucleic acid probes for DNA/RNA assays
07/20/1988EP0274700A1 Substrates for hydrolases
07/19/1988US4758516 Molecular cloning and characterization of a further gene sequence coding for human relaxin
07/19/1988US4758507 Products displaying the antigenicity of hepatitis B virus e antigens and methods of producing those antigens
07/14/1988WO1988005074A1 Porous wafer for segmented synthesis of biopolymers
07/14/1988WO1988004932A1 Vaccines and diagnostic assays for haemophilus influenzae
07/14/1988WO1988002406A3 Methods of regulating metabolic stability of proteins
07/12/1988US4757141 Conjugates with oligonucleotides
07/12/1988US4757055 Binding herpes virus with nonionic oligonucleoside alkyl or arylphosphonate complementary to base sequence of virus
07/06/1988EP0273373A2 Novel peptides and production thereof
07/06/1988EP0273115A2 Chemiluminescent acridinium and phenanthridinium salts
07/05/1988US4755363 Alternatively employing batch-wise, vapor diffusion or free interface diffusion procedures
06/1988
06/30/1988WO1988004690A1 New plasminogen activators
06/30/1988WO1988004689A1 Primary biliary cirrhosis autoantigen
06/29/1988EP0272928A2 Compositions and methods for the synthesis and assay of enkephalinase
06/29/1988EP0272321A1 A DNA SEQUENCE ENCODING THE $i(MAS) ONCOGENE, POLYPEPTIDES ENCODED THEREFROM, AND DIAGNOSTIC AND OTHER METHODS BASED THEREON
06/28/1988US4754065 Precursor to nucleic acid probe
06/28/1988US4753985 Oligopeptides recovered from a synthesizing gel
06/28/1988US4753795 Modified (80-113) beta interferons
06/28/1988CA1238591A1 Recombinant dna cosmid shuttle vectors
06/21/1988CA1238277A1 Antiviral nucleosides
06/16/1988WO1988004324A1 Pulmonary hydrophobic surfactant-associated proteins
06/16/1988WO1988004301A1 alpha OLIGONUCLEOTIDES
06/16/1988WO1988004300A1 Rna ribozyme polymerases, dephosphorylases, restriction endoribonucleases and methods
06/15/1988EP0270946A2 Chromogenic acridinone enzyme substrates
06/15/1988EP0270651A1 Novel deoxyribonucleoside phosphoramidites and their use for the preparation of oligonucleotides.
06/15/1988EP0270611A1 TRANSLATION OF mRNA.
06/14/1988US4751313 Nonradioactive labeling
06/08/1988EP0270017A2 Method of isolating and purifying nucleic acids from biological samples
06/08/1988EP0269677A1 ASSAYS AND ANTIBODIES FOR N-$i(myc) PROTEINS
06/08/1988EP0124562B1 Process for the production of oligonucleotides
06/08/1988CN87108073A Detection of htlvi and htlvii viruses by hybridization
06/07/1988US4749650 Guanosine, xanthosine production
06/07/1988CA1237685A1 Process for amplifying nucleic acid sequences
06/02/1988WO1988003926A1 Enhancing gamma-carboxylation of recombinant vitamin k-dependent proteins
06/02/1988WO1988003807A2 Production and use of a novel t-cell suppressor factor
06/01/1988EP0269445A2 Process for detecting HTLVI and HTLVII viruses by hybridization
06/01/1988EP0269072A2 Cloning of DNA encoding human gip precursor and expression of the precursor