Patents
Patents for C07H 21 - Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids (89,892)
05/1990
05/08/1990US4923804 Chromogens, indoxyl-b-d-glucuronide, glucuronidase activity
05/08/1990CA1268721A1 Hydrid promoters let and lec
05/07/1990CA2002380A1 Mixed ligand complexes and uses thereof as binding agents and probes to dna
05/03/1990WO1990004786A1 Hapten derivatized capture membrane and diagnostic assays using such membrane
05/03/1990WO1990004640A1 cDNAs CODING FOR THE η SUBUNIT OF THE HIGH-AFFINITY RECEPTOR FOR IMMUNOGLOBULIN E
05/03/1990WO1990004410A1 A novel family of high affinity, modified antibodies for cancer treatment
05/02/1990EP0365997A2 A novel family of high affinity, modified antibodies for cancer treatment
05/02/1990EP0365668A1 Device for carrying out a sequence of chemical reactions.
05/02/1990EP0365663A1 Methods for detecting nucleic acid sequences
05/02/1990EP0365657A1 Dna encoding androgen receptor protein
05/02/1990EP0135587B1 Defined sequence single strand oligonucleotides incorporating reporter groups, process for the chemical synthesis thereof, and nucleosides useful in such synthesis
05/01/1990US4922101 Radiation image-reading method
05/01/1990CA1268404A1 Polynucleotide assay reagent and method
04/1990
04/25/1990EP0364509A1 Cellular toxic conjugates
04/25/1990EP0224577B1 Method for derivitization of polynucleotides
04/24/1990US4920048 Method for stabilizing extra-chromosomal elements in bacteria during cultivation
04/19/1990WO1990004030A1 Sequences of nucleotides coding for a protein having an ureasic activity
04/17/1990US4917887 Viricides
04/17/1990CA2000810A1 Hapten derivatized capture membrane and diagnostic assays using such membrane
04/11/1990EP0363059A1 Antiviral oligomers
04/11/1990EP0362290A1 Cloning of mite allergens
04/11/1990EP0108787B1 The manufacture and expression of structural genes
04/10/1990US4916073 Complementary dna
04/10/1990US4916071 Poly-kringle plasminogen activator
04/10/1990US4916070 Fibrin-specific antibodies and method of screening for the antibodies
04/10/1990EP0289586A4 Enhancing gamma-carboxylation of recombinant vitamin k-dependent proteins.
04/05/1990WO1990003384A1 Antiviral oligomers
04/05/1990WO1990003383A1 Phosphorothioate and normal oligodeoxynucleotides with 5'-linked acridine
04/05/1990WO1990003382A1 Support-bound oligonucleotides
04/05/1990WO1990003381A1 Method of synthesis of alpha oligoribonucleotides and compounds useful for the method
04/05/1990WO1990003370A1 DERIVATIVES OF PYRAZOLO[3,4-d]PYRIMIDINE
04/04/1990EP0362179A2 Recombinant saccharomyces
04/04/1990EP0361768A2 Enzyme-nucleic acid hydrazone and hydrazide conjugate compositions, probes and methods
04/04/1990EP0361284A2 T cell growth factor
04/04/1990EP0360940A2 Polynucleotide determination with selectable cleavage sites
04/03/1990US4914210 Oligonucleotide functionalizing reagents
03/1990
03/28/1990EP0360676A1 Method for sequencing of nucleic acids
03/28/1990EP0360626A1 Process for the synthesis of alpha-oligoribonucleotides, and components useful in the process
03/28/1990EP0360257A2 RNA catalyst for cleaving specific RNA sequences
03/27/1990US4912207 Genetic engineering
03/27/1990US4912092 Prevent tissue damage; administering purine nucleoside
03/22/1990WO1990002820A1 Replicative rna-based amplification/detection systems
03/22/1990WO1990002819A1 Replicative rna-based amplification detection systems
03/22/1990WO1990002747A1 Red-shifted phthalocyanine and tetrabenztriazaporphyrin reagents
03/21/1990EP0359225A2 Reagents for the preparation of 5'-tagged oligonucleotides
03/20/1990US4910300 Method for making nucleic acid probes
03/20/1990CA1266950A1 Method and apparatus for multipolymer synthesis systems
03/14/1990CN1040321A Therapeutic uses of 2,5-oligoadenylate derivatives
03/13/1990US4908453 Reagents for the preparation of 5'-biotinylated oligonucleotides
03/13/1990US4908405 Graft copolymers of crosslinked polymers and polyoxyethylene, processes for their production, and their usage
03/13/1990CA1266628A1 Manufacture and expression of structural genes
03/13/1990CA1266627A1 Use of a recombinant dna comprising a nucleotide sequence coding for a given polypeptide under the control of an adenovirus promoter
03/08/1990WO1990002207A1 Cloned nephritis antigen
03/08/1990WO1990002203A1 Detection of human tumor progression and drug resistance
03/07/1990EP0357336A2 Method for detection of specific nucleic acid sequences
03/07/1990EP0357157A2 Procaryotic carbonyl hydrolases and mutants thereof, and methods for producing and using them
03/07/1990EP0357127A1 Gene replacement as a tool for the construction of aspergillus strains
03/07/1990EP0357119A2 A method for enhancing production of secondary metabolites using clustered biosynthetic genes
03/07/1990EP0357028A2 Nucleic-acid fragments from eucaryotic genomes, method for their production and their use in the detection of restriction fragment length polymorphisms (RFLPs)
03/07/1990EP0357024A2 Dipoprotein I (OMPI) from Pseudomonas aeruginosa
03/07/1990EP0357011A2 Detection and amplification of target nucleic acid sequences
03/07/1990CN1040220A Method for amplification of nucleotide sequences
02/1990
02/28/1990EP0356021A2 A method for the amplification of nucleotide sequences
02/28/1990EP0355266A2 Apparatus for performing repetitive chemical reactions
02/27/1990US4904582 Novel amphiphilic nucleic acid conjugates
02/26/1990EP0248896A4 Amplified hybridization assay.
02/21/1990CN1039722A Diagnosing and treating viral infections associated with chronic fatigue
02/14/1990CN1039618A Method of detecting nucleotide sequences
02/13/1990US4900822 New hydrolase substrates
02/13/1990US4900659 Nucleotide sequence composition and method for detection of Neisseria gonorrhoeae and method for screening for a nucleotide sequence that is specific for a genetically distinct group
02/13/1990CA1265756A1 Carriers, the process for their preparation, the intermediates obtained, their use in the synthesis of oligonucleotides and the nucleosides and oligonucleotides binded to the carriers thus obtained
02/08/1990WO1990001069A1 Process for amplifying and detecting nucleic acid sequences
02/08/1990WO1989009788A3 Biosynthetic osteogenic proteins and osteogenic devices containing them
02/08/1990WO1989009787A3 Osteogenic devices
02/07/1990EP0353985A2 Nucleic acid probe for detection of neisseria gonorrhoea
02/07/1990EP0353290A1 Selective inhibition of gene expression by photoactivatable oligonucleotides
02/06/1990US4898951 Aromatic amines
01/1990
01/31/1990EP0353124A1 Process for labelling a nucleic-acid probe and set of reagents for carrying out the process
01/31/1990EP0352904A1 Tissue plasminogen activator analogues
01/31/1990CN1039250A Porous wafer for segmented synthesis of biopolymers
01/30/1990US4897471 Consensus human leukocyte interferon
01/25/1990WO1990000626A1 Solid phase assembly and reconstruction of biopolymers
01/25/1990WO1990000624A1 Antisense oligonucleotide antibiotics complementary to the macromolecular synthesis operon, methods of treating bacterial infections and methods for identification of bacteria
01/25/1990WO1990000622A1 Oligonucleotide hybridization probes and means for the synthesis of the most preferred probes
01/25/1990WO1990000606A1 Polynucleotides that encode the human proteoglycan peptide core of the effector cells of the immune response
01/25/1990WO1990000569A1 Acid-labile subunit (als) of insulin-like-growth factor (igf) binding protein complex
01/25/1990WO1990000565A1 Interleukin ii analogs
01/25/1990WO1990000558A1 Leader sequence inducing a post-translational modification of polypeptides in bacteria, and gene therefor
01/25/1990WO1990000556A1 Synthetic hiv protease gene and method for its expression
01/24/1990EP0352089A2 A modified human PSTI
01/23/1990US4895955 Non-radioactive carbodiimide precursor to nucleic acid probes
01/23/1990US4895800 Biosynthesis, pichia, genetic engineering
01/23/1990CA1264738A1 Treatment of tumors in mammals
01/23/1990CA1264686A1 Portable inducible control system
01/18/1990DE3824110A1 Process for the preparation and purification of oligo- and polynucleotide sequences phosphorylated on their 5-ends and reagents for carrying out the process
01/17/1990EP0155950B1 Oligonucleotide polymeric support system
01/16/1990US4894443 Polypeptides, antibodies
01/16/1990US4894338 Dna, gene expression, cloning
01/16/1990US4894325 Targets, polynucleotied, genetic engineering
01/16/1990CA1264452A1 Large scale production of dna probes