Patents
Patents for C07H 21 - Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids (89,892)
02/1993
02/04/1993WO1993002093A1 Modified phosphorous intermediates for providing functional groups on the 5' end of oligonucleotides
02/03/1993EP0525917A2 Double-stranded RNA correction of aberrant metabolic pathways associated with uncontrolled tumor cell and virus growth cycles
02/03/1993EP0525882A1 Quantification of nucleic acid
02/03/1993EP0525821A2 Methods and structures employing non-radioactive chemically-labeled polynucleotide probes
02/03/1993EP0525181A1 Novel lanthanide chelate-conjugated oligonucleotides.
02/03/1993EP0525076A1 Recombinant bile salt activated lipases
02/03/1993EP0524997A1 2'-o-alkyl nucleotides and polymers containing them.
02/03/1993EP0524942A1 Method of synthesizing sulfurized oligonucleotide analogs
02/03/1993EP0288513B1 Hybridization assay and means to be used in the assay
02/02/1993US5183885 Method for chromatographic separation of synthetic phosphorothioate oligonucleotides
02/02/1993US5183748 By synthesizing the complementary strand of a single-stranded DNA piece enzymatically
02/02/1993CA1313359C Method of isolating and purifying nucleic acids from biological samples
01/1993
01/27/1993EP0524864A1 Method for immobilizing a nucleic acid fragment by passive adsorption on a solid support, solid support obtained therefrom and its utilisation
01/27/1993EP0524604A2 Process for the preparations of S-(+)-2,2-dimethyl-cyclopropane carboxamid by genetically engineered microorganismes
01/26/1993US5182366 Simplified method of forming identifiable sequences of amino acids
01/21/1993WO1993001204A1 Method and compounds for rna synthesis
01/21/1993DE4223438A1 Cyclische oligonucleotidphosphorthioate Cyclic oligonucleotidphosphorthioate
01/20/1993EP0523978A1 Modified phosphorous intermediates for providing functional groups on the 5' end of oligonucleotides
01/20/1993EP0523557A1 Immobilisation of nucleic acids
01/20/1993EP0523140A1 Reagents and methods for modulating gene expression through rna mimicry
01/20/1993CN1068035A Abrogation of uiral resistance to nucleoside analogues by double-stranded rnas
01/20/1993CN1068017A Yogourt
01/19/1993US5180820 Nucleic acid sequence code
01/19/1993US5180668 Hirudin derivative
01/17/1993CA2073989A1 Immobilization of nucleic acids
01/12/1993US5179200 Nucleosides
01/12/1993US5178859 Monoclonal antibodies for binding an antigen of Borrelia and epitopes
01/12/1993CA1312567C Yeast strains with reduced intracellular atp levels
01/07/1993WO1993000447A1 Amplification of target nucleic acids using gap filling ligase chain reaction
01/07/1993WO1993000352A1 Sequence-specific binding polymers for duplex nucleic acids
01/07/1993WO1992019770A3 Process for the in vitro diagnosis of chromosomal anomalies correlated with cmt1a disease
01/07/1993EP0521586A1 FSH and other recombinant hormones
01/07/1993EP0506830A4 Uncharged morpholino-based polymers having phosphorous-containing chiral intersubunit linkages
01/07/1993EP0484440A4 Efficient directional genetic cloning system
01/07/1993EP0418309A4 Oligonucleotide analogs containing sulfur
01/05/1993US5177198 Process for preparing oligoribonucleoside and oligodeoxyribonucleoside boranophosphates
01/05/1993US5177196 Used for diagnostic and chemotherapeutic purposes
01/05/1993US5176996 Method for making synthetic oligonucleotides which bind specifically to target sites on duplex DNA molecules, by forming a colinear triplex, the synthetic oligonucleotides and methods of use
12/1992
12/30/1992EP0520014A1 Multichromophore fluorescent probes
12/30/1992EP0395672B1 Antiviral application of alpha oligonucleotides
12/29/1992WO1993001286A2 Localized oligonucleotide therapy
12/29/1992US5175273 Pyridinone or pyrimidinone nucleoside bases containing fused aromatic polycyclic rings
12/29/1992US5175209 Porous wafer for segmented synthesis of biopolymers
12/29/1992US5175082 Method of characterizing genomic dna
12/29/1992US5174962 Apparatus for determining DNA sequences by mass spectrometry
12/23/1992WO1992022671A1 Polynucleotide determination with selectable cleavage sites
12/23/1992WO1992022303A1 Selective inhibition of leukemic cell proliferation by bcr-abl antisense oligonucleotides
12/23/1992EP0519463A1 Synthetic, catalytic oligonucleotides
12/23/1992CA2110591A1 Polynucleotide determination with selectable cleavage sites
12/23/1992CA2103377A1 Selective inhibition of leukemic cell proliferation by bcr-abl antisense oligonucleotides
12/22/1992US5173294 Purified antiserum which recognizes homophilus influenzae outer membrane protein for treating diseases caused by pathogen
12/16/1992EP0518443A1 Recombinant proteins of viruses associated with lymphadenopathy syndrome and/or acquired immune deficiency syndrome
12/16/1992EP0518096A1 Yogurt containing living microorganisms
12/16/1992EP0517859A1 Oligonucleotide therapies for modulating the effects of herpesviruses
12/16/1992EP0517829A1 Improved chimeric toxins
12/16/1992EP0517796A1 Oligonucleotide analogs.
12/16/1992EP0517704A1 Primers and process for detecting human papillomavirus genotypes by pcr.
12/15/1992CA1311428C Deoxyribonucleoside phosphoramidites in which an aliphatic amino group is attached to the sugar ring and their use for the preparation of oligonucleotides containing aliphatic amino groups, fluorescent dyes, and other detectable moieties
12/10/1992WO1992021692A1 Oligo-2'-deoxynucleotides and their use as drugs with an antiviral action
12/10/1992WO1992021691A1 2',5'-nucleotide analogs as antiviral agents
12/10/1992WO1992021353A1 Compositions and delivery systems for transdermal administration of neutral oligomers
12/10/1992WO1992014821A3 Nestin expression as an indicator of neuroepithelial tumors
12/10/1992CA2110040A1 Compositions and delivery systems for transdermal administration of neutral oligomers
12/08/1992WO1992022561A1 A process for synthesis of silyl alcohols
12/08/1992WO1992021689A1 Silyl phosphorylating reagents and methods of using them
12/08/1992US5169941 DNA sequences coding for the DR β-chain locus of the human lymphocyte antigen complex and polypeptides, diagnostic typing processes and products related thereto
12/08/1992CA2107911A1 Silyl phosphorylating reagents and methods of using them
12/08/1992CA2107909A1 A process for the synthesis of silyl alcohols
12/08/1992CA1311201C Desazapurine-nucleoside derivatives, processes for the preparation thereof, pharmaceutical compositions containing them and the use thereof fornucleic acid sequencing and as antiviral agents
12/07/1992WO1992021375A1 Causative agent of the mystery swine disease, vaccine compositions and diagnostic kits
12/06/1992WO1992021690A1 Purine base modified 2'-deoxyribonucleosides, use in triplex forming oligonucleotides and process for preparing the same
12/06/1992CA2088787A1 Purine base modified 2'-deoxyribonucleosides, use in triplex forming oligonucleotides and process for preparing the same
12/02/1992EP0516396A1 Eimeria acervulina dna probes
12/02/1992EP0515569A1 Calcium channel compositions and methods
12/02/1992EP0515395A1 Sapphyrins, derivatives and synthesis
12/02/1992EP0450048A4 Stable mammalian cell lines that express aromatase
12/01/1992US5168049 Production of streptavidin-like polypeptides
11/1992
11/30/1992CA2069583A1 Eimeria acervulina dna probes
11/26/1992WO1992020823A1 Backbone modified oligonucleotide analogs
11/26/1992WO1992020822A1 Backbone modified oligonucleotide analogues
11/26/1992WO1992020821A1 cDNA-PHOTOFLUOR PROBE AND METHODS OF MAKING, ASSAYING AND USING SAME
11/26/1992WO1992020801A1 Novel antipathogenic peptides and compositions containing same
11/26/1992WO1992020703A1 The use of nucleic acid analogues in diagnostics and analytical procedures
11/26/1992WO1992020702A1 Peptide nucleic acids
11/26/1992WO1992020698A1 Sequence specific dna binding drugs
11/26/1992WO1992020348A1 Treatment of colorectal carcinoma with antisense oligonucleotides to c-myb proto-oncogene
11/26/1992DE4117186A1 Oligo-2'-desoxynukleotide und ihre verwendung als arzneimittel mit antiviraler wirksamkeit Oligo-2'-deoxynucleotides and their use as medicaments having antiviral efficacy
11/26/1992CA2109829A1 Treatment of colorectal carcinoma with antisense oligonucleotides to c-myb proto-oncogene
11/26/1992CA2109805A1 The use of nucleic acid analogues in diagnostics and analytical procedures
11/26/1992CA2103378A1 Backbone modified oligonucleotide analogues
11/26/1992CA2083272A1 Novel antipathogenic peptides and compositions containing same
11/25/1992EP0514513A1 Method and means for oligonucleotide synthesis.
11/25/1992EP0514488A1 Retinoid receptor compositions and methods
11/25/1992EP0427745A4 Solid phase assembly and reconstruction of biopolymers
11/24/1992US5166387 Method of synthesizing sulfurized oligonucleotide analogs with thiuram disulfides
11/24/1992US5166330 Process for the preparation of nucleoside alkyl-aralkyl- and aryl-phosphonites and -phosphonates
11/24/1992US5166315 Sequence-specific binding polymers for duplex nucleic acids
11/24/1992CA1310600C Oligonucleotide functionalizing reagents and methods
11/22/1992CA2103464A1 Backbone modified oligonucleotide analogs
11/19/1992EP0513849A2 Zea mays plants and transgenic Zea mays plants regenerated from protoplasts or protoplast-derived cells