Patents
Patents for C07H 21 - Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids (89,892)
06/1988
06/01/1988EP0268946A2 Method for separating long-chain nucleic acids
06/01/1988EP0268636A1 Fc receptor for immunoglobulin.
05/1988
05/31/1988US4748118 Construction of arsenic resistance vectors for Thiobacillus ferrooxidans
05/25/1988EP0268561A2 Production and use of a novel T-cell suppressor factor
05/25/1988EP0267996A1 New nucleotide derivatives
05/19/1988WO1988003563A1 Fusion proteins and particles
05/19/1988WO1988003533A1 Construction of synthetic dna and its use in large polypeptide synthesis
05/18/1988EP0267521A2 Method for the detection of nucleic acid hybrids
05/17/1988US4745054 Enzyme labels
05/11/1988EP0266399A1 Replicative rna reporter systems.
05/10/1988US4744037 Polynucleotide synthesizing apparatus
05/10/1988CA1236410A1 Nucleic acid hybridization assay
05/05/1988WO1988003172A1 DNA EXPRESSING Fc RECEPTOR PROTEIN
05/05/1988WO1988003149A1 Process for synthesizing oligonucleotides and compounds for forming high-molecular protective group
05/05/1988WO1988003032A1 Diagnosis of and vaccine for japanese encephalitis virus and related viruses
05/04/1988EP0266168A2 Compositions and methods for the synthesis of oligonucleotides having 5'-phosphorylated termini
05/04/1988EP0266099A2 Oligonucleoside alkyl or arylphosphonate derivatives capable of crosslinking with or cleaving nucleic acids
05/04/1988EP0265519A1 Electrochemiluminescent assays.
05/04/1988CN87104489A Herbicid resistance plant consisting glutathione s-transferase
04/1988
04/27/1988CN87104424A Human erythropoietin gene high level expression in stably transfected mammalian cells
04/27/1988CN87102927A Improvements in genetic probes
04/21/1988WO1988002784A1 Hybridization assay and means to be used in the assay
04/20/1988EP0263933A1 A cDNA coding for carcinoembryonic antigen
04/20/1988EP0111005B1 Fucosyl antigens, a process for their preparation and antibodies for recognising them, a cancer diagnosing kit containing the fucosyl antigens and a method for determination of cancer associated carbohydrate linkages
04/20/1988EP0053135B1 Production of ifn-gamma
04/19/1988US4739045 Process for the dissolution of nucleotides and polynucleotides
04/19/1988US4739044 Method for derivitization of polynucleotides
04/19/1988US4738928 Method for cloning genes
04/19/1988US4738845 Viricides, antitumor agents
04/19/1988US4738844 Antivcral, antitumor, immunomodulatory agents
04/13/1988EP0263740A1 Coupling conjugates between RNA or DNA sequences and a protein, method for their preparation and their biological use
04/12/1988US4737454 Fast photochemical method of labelling nucleic acids for detection purposes in hybridization assays
04/12/1988US4736866 Recombinant activated oncogene; early transgenic animal patent
04/12/1988CA1235079A1 Process for the preparation of nucleoside alkyl-, aralkyl- and aryl-phosphonites and -phosphonates
04/07/1988WO1988002407A1 Recombinant dna clone encoding laminin receptor
04/07/1988WO1988002406A2 Methods of regulating metabolic stability of proteins
04/06/1988EP0263072A2 Novel lymphokine related peptides
04/06/1988EP0262212A1 Biotinylated psoralens
03/1988
03/30/1988EP0262043A1 DNA sequence vectors, recombinant viruses and method of using recombinant vaccinia viruses capable of multiplying in CHO cells
03/30/1988EP0261625A2 Human B-cell differentiation factor and process of producing said factor
03/30/1988EP0261283A1 Amino-derivatized phosphite and phosphate linking agents, phosphoramidite precursors and useful conjugates thereof
03/29/1988US4734363 Genetic engineering
03/29/1988US4734362 Process for purifying recombinant proteins, and products thereof
03/29/1988CA1234547A1 Process for the dissolution of nucleotides and polynucleotides in non-aqueous solvents and mixed non-aqueous/aqueous solvent systems, solutions thereby obtained and their use
03/24/1988WO1988002004A1 Amino-derivatized phosphite and phosphate linking agents, phosphoramidite precursors, and useful conjugates
03/23/1988EP0261009A1 DNA sequence exercizing a function characterized by an overproduction of extracellular proteins from different bacillus strains, and vectors containing this sequence
03/23/1988EP0260610A2 Monoclonal antibodies against human tumour necrotic factor (TNF), and their use
03/16/1988EP0260032A2 Compounds for the cleavage at a specific position of RNA, oligomers employed for the formation of said compounds, and starting materials for the synthesis of said oligomers
03/16/1988EP0259632A1 Expression of biologically active PDGF analogs in eucaryotic cells
03/15/1988US4731325 Arrays of alternating nucleic acid fragments for hybridization arrays
03/15/1988CA1234061A1 Labeled dna
03/15/1988CA1234060A1 Process for the preparation of oligonucleotides
03/10/1988WO1988001649A1 Single polypeptide chain binding molecules
03/09/1988EP0259186A2 Non-radioactive nucleic acid hybridization probes
03/02/1988EP0258118A1 Process for stabilizing a plasmid contained in a bacterial strain, and strain obtained
03/02/1988EP0257095A1 Construction and applications of polyproteins
03/01/1988US4728609 Recombinant growth hormone releasing factor
03/01/1988US4728502 Apparatus for the chemical synthesis of oligonucleotides
02/1988
02/25/1988WO1988001304A1 Dna encoding the t cell surface protein t4 and use of fragments of t4 in the treatment of aids
02/25/1988WO1988001295A1 Dna sequence exerting a function of overproduction of exocellular proteins by various strains of bacillus, and vectors containing such sequence
02/25/1988WO1988001273A1 Diagnostic assay for inhibitor of tissue-type and urokinase-type plasminogen activators, and gene coding for the inhibitor
02/24/1988EP0256654A2 Chimeric murine/human immunoglobulin specific for tumour-associated 17-1A Antigen
02/24/1988EP0256630A1 Specific probes for the identification of mutations in the human phenylalanine hydroxylase gene
02/24/1988EP0256223A1 Herbicide tolerant plants containing a glutathione-S-transferase gene
02/24/1988EP0256055A1 Recombinant dna sequences, vectors containing them and method for the use thereof.
02/23/1988US4727138 Human immune interferon
02/16/1988US4725677 Process for the preparation of oligonucleotides
02/16/1988US4725557 Production of fucosyl antigens and antibodies for recognizing same determination of cancer associated carbohydrate linkage using same and kit for the determination
02/11/1988WO1988000973A1 Recombinant plasmid dnas, coding for synthesis of polypeptide substances for a vaccine against hepatitis a
02/11/1988WO1988000948A1 Method to control and produce novel biopolymers
02/11/1988WO1988000831A1 Dna sequences coding for modified factor viii:c and modified factor viii:c-like polypeptides and processes for producing these polypeptides in high yields
02/10/1988EP0255771A1 Recombinant dna encoding mature human protein s.
02/03/1988EP0255231A1 Human erythropoietin gene: high level expression in stably transfected mammalian cells
02/02/1988US4722897 Viral enhancer DNA segments
01/1988
01/28/1988WO1988000593A1 Nucleic acid detection probes containing deoxy-2' adenosine derivatives
01/28/1988EP0244471A4 Lanthanide chelate-tagged nucleic acid probes.
01/27/1988EP0254646A1 Probes containing 2'-deoxy-adenosine derivatives for nucleic acids
01/27/1988EP0254345A2 Immune interferon
01/27/1988EP0254249A1 Preparation of binding factor related polypeptides
01/27/1988CN86108579A Mammalian interleukin-4
01/26/1988US4721672 CDNA and gene for human angiogenin (angiogenesis factor) and methods of expression
01/26/1988US4721669 Chemical probes for left-handed DNA and chiral metal complexes as Z-specific anti-tumor agents
01/20/1988EP0253701A1 Variants of lav viruses, their dna- and protein components and their uses, particularly for diagnostic purposes and for the preparation of immunogenic compositions
01/20/1988EP0253693A1 Vaccine containing the AIDS virus F protein
01/20/1988EP0253455A1 Method for the preparation of proteins with factor VIII activity by microbial host cells; expression vectors, host cells, antibodies
01/20/1988EP0253193A2 Method for mutagenesis by oligonucleotide-directed repair of a strand break
01/20/1988CN87103688A Process for obtaining chemically defined and reproducible polydeoxy-ribonucleotide
01/19/1988CA1231651A1 Recombinant dna expression vectors useful in bacillus and other host cells
01/19/1988CA1231650A1 Defined sequence single strand oligonucleotides incorporating reporter groups, process for the chemical synthesis thereof, and nucleosides useful in such synthesis
01/14/1988WO1988000241A1 Human erythropoietin gene: high level expression in stably transfected mammalian cells
01/14/1988WO1988000201A1 Novel deoxyribonucleoside phosphoramidites and their use for the preparation of oligonucleotides
01/13/1988EP0252683A2 Process and reagents for DNA sequence analysis
01/13/1988EP0252531A1 Structural phosphoprotein (pp 150) of human cytomegalovirus, its preparation and use
01/13/1988EP0252405A2 3-methoxy-4-hydroxyphenylglycol fluorescence polarization immunoassay
01/13/1988EP0252146A1 Nuclear factors associated with transcriptional regulation.
01/12/1988US4719180 Genetic engineering
01/12/1988US4719179 Six base oligonucleotide linkers and methods for their use
01/12/1988US4719177 Genetic engineering
01/07/1988EP0251786A2 Alkynylamino-nucleotides
01/07/1988EP0251575A1 Hepatitis delta diagnostics and vaccines, their preparation and use