Patents
Patents for C07H 21 - Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids (89,892)
06/1992
06/12/1992CA2098187A1 Methods for labelling oligonucleotides
06/12/1992CA2057475A1 3'-(2')-amino- or thiol-modified, fluorescent dye-coupled nucleosides, nucleotides and oligonucleotides, and a process for the preparation and the use thereof
06/11/1992WO1992009705A1 Triplex-forming oligomers containing modified bases
06/11/1992WO1992009693A1 Human parainfluenza virus type 4a fusion protein and gene which codes for the same
06/11/1992WO1992009615A1 Method and means for oligonucleotide synthesis
06/11/1992WO1992002534A3 Compounds and methods for inhibiting gene expression
06/11/1992CA2057292A1 Labelled, modified oligonucleotides
06/10/1992EP0489058A1 Cystic fibrosis gene
06/10/1992EP0437576A4 Homologous recombination for universal donor cells and chimeric mammalian hosts
06/10/1992EP0425563A4 Process for amplifying and detecting nucleic acid sequences
06/09/1992US5120837 Dna encoding phe a feedback inhibition resistant enzyme analogues
06/09/1992CA1303033C Solution phase nucleic acid sandwich assay and polynucleotide probes useful therein
06/07/1992WO1992010092A1 Very large scale immobilized polymer synthesis
06/07/1992CA2097708A1 Very large scale immobilized polymer synthesis
06/03/1992EP0488479A1 DNA sequences, recombinant DNA molecules and processes for producing swine growth hormone-like polypeptides
06/03/1992EP0487718A1 NUCLEIC ACID PROBES with negatively charged haptens which are attached to the probe via a hydrazine binding moiety
06/03/1992EP0487709A1 Dna probes and primers for detection of b. burgdorferi using the polymerase chain reaction.
06/03/1992EP0487694A1 Oligonucleotide functionalization method
06/03/1992EP0452420A4 End-attachment of oligonucleotides to polyacrylamide solid supports for capture and detection of nucleic acids
06/03/1992EP0333832B1 Artificial dna base pair analogues
06/02/1992US5118802 DNA-reporter conjugates linked via the 2' or 5'-primary amino group of the 5'-terminal nucleoside
06/02/1992US5118800 Oligonucleotides possessing a primary amino group in the terminal nucleotide
06/02/1992US5118622 Polypeptide possessing isoamylase activity, and its use in the hydrolysis of amylaceous substances
06/02/1992US5118605 Polynucleotide determination with selectable cleavage sites
05/1992
05/29/1992WO1992008717A1 Substituted 1,3-oxathiolanes and substituted 1,3-dithiolanes with antiviral properties
05/28/1992CA2030967A1 Modular procedure used with a engineered dna implant for physical mapping/overlapping chromosomes with ready for gene isolation/ ready for sequencing contigs
05/27/1992EP0487512A1 Production of heterodimeric human fertility hormones
05/27/1992EP0486580A1 Process and device for separating and detecting constituents of a mixture of substances by temperature gradient gel electrophoresis.
05/26/1992CA1301675C Polycistronic expression vector construction
05/26/1992CA1301673C Method for derivitization of polynucleotides
05/21/1992WO1992008729A1 Antisense nucleic acid derivative
05/21/1992CA2096658A1 Anti-sense nucleic acid derivative
05/20/1992EP0428707A4 Steroid modified oligonucleotides
05/20/1992CN1061245A Bioassay for detention of b. burgdorferi
05/19/1992US5114711 Covalently linked polypeptide cell modulators such as interferon-lymphotoxin conjugates
05/16/1992CA2055302A1 Specific microbial strain detection method
05/14/1992WO1992007942A1 Polypeptides involved in the expression of resistance to glycopeptidic antibiotics
05/14/1992WO1992007882A1 Non-aromatic organic polymeric reagents for solid phase synthesis of oligomers
05/14/1992CA2094595A1 Non-aromatic organic polymeric reagents for solid phase synthesis of oligomers
05/13/1992EP0485156A1 Methods and compounds for labeling DNA with xanthine and lower alkyl substituted xanthine derivatives and reagents for the in situ detection of chromosomes
05/13/1992EP0485155A1 Novel labeling reagents useful for the chemical attachment of nitrophenyl derivative ligands to DNA probes
05/13/1992EP0484440A1 Efficient directional genetic cloning system
05/13/1992EP0386228A4 Replicative rna-based amplification/detection systems
05/12/1992US5113005 Process for synthesis of silyl alcohols
05/12/1992US5112974 Mixed ligand complexes and uses thereof as binding agents to DNA
05/12/1992US5112963 Modified oligonucleotides
05/12/1992US5112962 Oxalyl derivative provides quick release of product using mild conditions
05/12/1992US5112753 Method of identification and preparation of probes for pestiviruses, oligonucleotides and probes thus obtained and a method of detection of pestiviruses
05/12/1992CA1300532C Covalent oligonucleotide-horseradish peroxidase conjugate
05/09/1992WO1992008728A1 Incorporation of multiple reporter groups on synthetic oligonucleotides
05/09/1992CA2095212A1 Incorporation of multiple reporter groups on synthetic oligonucleotides
05/07/1992CA2095428A1 Test for virulent revertants in attenuated live vaccines
05/06/1992EP0483911A2 Chicken anemia virus vaccine and diagnostic reagent
05/06/1992EP0433363A4 Replicative rna-based amplification detection systems
05/06/1992EP0299082B1 Antiviral agent
05/05/1992US5110802 Oligonucleotide phosphonates and method of inhibiting a human immunodeficiency virus in vitro utilizing said oligonucleotide phosphonates
05/05/1992US5110730 Human tissue factor related DNA segments
05/05/1992CA1300052C Episomal vector for the expression of selected dna fragments coding for optional polypeptides in mammalian cells and methods for the production thereof
05/05/1992CA1300051C Phosphorylating reagents and method of using the same
05/01/1992CA2054542A1 Chicken anemia virus vaccine and diagnostic
04/1992
04/30/1992WO1992007096A1 Mehods and pharmaceutical kits useful for detecting microorganisms associated with vaginal infections
04/30/1992WO1992007065A1 Modified ribozymes
04/30/1992WO1992006988A1 Method for the production of catalytic rna in bacteria
04/30/1992CA2071854A1 Method for the production of catalytic rna in bacteria
04/29/1992EP0483115A2 Regulatory region for heterologous gene expression in yeast
04/29/1992EP0483113A2 A method of producing an enzymatically active polypeptide analog of human Cu/Zn SOD
04/29/1992EP0482671A1 Vaccine against varicella-zoster virus
04/29/1992EP0092574B1 Oligonucleotide therapeutic agent and methods of making same
04/28/1992US5109124 Nucleic acid probe linked to a label having a terminal cysteine
04/28/1992US5108921 Method for enhanced transmembrane transport of exogenous molecules
04/27/1992WO1992007864A1 Improved process for the synthesis of oligomers
04/27/1992CA2094803A1 Process for the synthesis of oligomers
04/23/1992WO1992006693A1 Dna construct for providing rna therapy
04/23/1992CA2094608A1 Dna construct for providing rna therapy
04/22/1992EP0481704A1 Amplification of midivariant DNA templates
04/22/1992EP0481215A1 Method for the detection of an HIV-1 genome by a two-step PCR method and oligonucleotide used in the same
04/21/1992US5106729 Replacing oxygen in polymer with sulfur, then complexing with metal; measuring difference in electroconductivity with tip of scanning probe microscope
04/21/1992US5106585 Chemical modification, adsorption, elution, cleavage at position of modified base
04/21/1992CA1299120C Stable dna constructs for expression of alpha-1-antitrypsin
04/21/1992CA1299119C Dna encoding a grf precursor
04/21/1992CA1299073C Nucleotide sequence composition and method for detection of neisseria gonorrhoeae and method for screening for a nucleotide sequence that is specific for genetically distinct group
04/17/1992CA2046713A1 Amplification of midivariant dna templates
04/16/1992WO1992006203A1 MUTANTS OF tPA WHICH ARE RESISTANT TO THEIR COGNATE SERPIN INHIBITOR
04/15/1992EP0480751A1 Method for labelling sugars
04/10/1992WO1992006192A1 Inhibition of viral replication
04/10/1992CA2093816A1 Inhibition of viral replication
04/08/1992EP0478708A1 Formation of triple helix complexes of double stranded dna using nucleoside oligomers
04/08/1992EP0478665A1 ANTIGENIC EPITOPES PRESENT ON MEMBRANE-BOUND BUT NOT SECRETED IgA
04/08/1992EP0378615A4 Nucleoside and polynucleotide thiophosphoramidite and phosphorodithioate compounds and processes
04/05/1992WO1992006103A1 Synthesis of oligonucleotides
04/05/1992CA2093356A1 Synthesis of oligonucleotides
04/02/1992WO1992005287A1 Enzymatic synthesis of oligonucleotides
04/02/1992WO1992005251A1 Dna sequence imparting cytoplasmic male sterility, mitochondrial genome, nuclear genome, mitochondria and plant containing said sequence and process for the preparation of hybrids
04/02/1992WO1992005195A1 Viral growth inhibition
04/02/1992WO1992005185A1 Probe compositions for chromosome identification and methods
04/02/1992WO1991019814A3 Dna probes and primers for detection of b. burgdorferi using the polymerase chain reaction
04/01/1992EP0477296A1 Prenatal bovine sex determination using male-specific oligonucleotides
04/01/1992EP0477248A1 Alpha anomer oligonucleotide compounds which inhibit retrovirus replication
04/01/1992EP0477220A1 Methods for tagging and tracing materials with nucleic acids.
03/1992
03/31/1992US5100788 Method of producing and isolating igg-binding protein a fusion peptides and a vector therefor