| Patents for C07H 21 - Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids (89,892) |
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| 05/16/1989 | US4831124 Recombinant cDNA construction method and hybrid nucleotides useful in cloning |
| 05/16/1989 | US4831120 Method for recovering a purified animal growth hormone or polypeptide analog thereof from a bacterial cell |
| 05/16/1989 | CA1254114A1 Displacement polynucleotide assay employing recombination protein and diagnostic kit |
| 05/14/1989 | EP0317077A1 Nucleic acid multimers and amplified nucleic acid hybridization assays using same |
| 05/10/1989 | EP0315499A1 Nucleoside derivatives, particularly of 2'-deoxycytidine, and their use in the synthesis of oligonucleotides |
| 05/10/1989 | EP0315254A1 Protein 7B2, recombinant DNA, cDNA and mRNA, and a method of detecting the mRNA |
| 05/10/1989 | EP0315081A2 Anti-coagulating protein PP4-x, its preparation and use |
| 05/10/1989 | CN1032741A Double-stranded rna correction of aberrant metabolic pathways associated with uncontrolled tumor cell |
| 05/10/1989 | CN1032740A Elaboration of host defense mediators into biological fluids by systemic ds rna treatment |
| 05/09/1989 | US4828979 Biotinylated |
| 05/09/1989 | CA1253777A1 Nucleic acid hybridization assay employing immobilized rna probes |
| 05/05/1989 | WO1989003891A1 Nucleic acid multimers and amplified nucleic acid hybridization assays using same |
| 05/05/1989 | WO1989003849A1 Oligonucleotide-polyamide conjugates |
| 05/05/1989 | WO1989003687A1 Composition and method for treating cancers characterized by over-expression of the c-fms proto-oncogene |
| 05/05/1989 | WO1989003683A1 2',5'-phosphorothioate oligoadenylates and antiviral uses thereof |
| 05/03/1989 | EP0313919A2 A novel synthesis of chemiluminescence labels for immuno assays |
| 04/26/1989 | EP0313219A2 Non-nucleotide linking reagents for nucleotide probes |
| 04/26/1989 | EP0313104A2 Purification, production and use of tumor necrosis factors |
| 04/25/1989 | US4824945 Hypocholesterolemically active RNA fractions |
| 04/25/1989 | US4824782 DNA base sequence, method for preparing a recombinant plasmid including the DNA base sequence, and breeding method for enhancing the protein-secreting ability of a microorganism by introducing thereinto the recombinant plasmid |
| 04/25/1989 | US4824775 Cells labeled with multiple Fluorophores bound to a nucleic acid carrier |
| 04/20/1989 | WO1989003217A1 ANTIVIRAL APPLICATION OF alpha OLIGONUCLEOTIDES |
| 04/19/1989 | EP0312248A2 Acridinium ester labelling and purification of nucleotide probes |
| 04/19/1989 | EP0312121A2 Yeast strains producing cellulolytic enzymes and methods and means for constructing them |
| 04/18/1989 | US4822742 Reaction tray for membrane hybridizations |
| 04/18/1989 | US4822731 Process for labeling single-stranded nucleic acids and hybridizaiton probes |
| 04/12/1989 | EP0311273A1 Transformation system for Penicillium |
| 04/12/1989 | EP0310913A2 DNA isolation procedure |
| 04/12/1989 | CN1032367A Dna construction with preceding sequence of kluyveromyces x-factor directing heterologous polypeptide excretion |
| 04/11/1989 | US4820812 Oligonucleotide derivatives and production thereof |
| 04/11/1989 | US4820638 Novel alpha interferon species produced by recombinant means |
| 04/06/1989 | WO1989002933A1 Non-nucleotide reagents for substituting termini of oligonucleotides |
| 04/06/1989 | WO1989002932A1 A covalent oligonucleotide-horseradish peroxidase conjugate |
| 04/06/1989 | WO1989002931A1 Oligonucleotide functionalizing reagents and methods |
| 04/06/1989 | WO1989002921A1 Artificial dna base pair analogues |
| 04/06/1989 | WO1989002896A1 Acridinium ester labelling and purification of nucleotide probes |
| 04/05/1989 | EP0310312A2 Non-nucleotide reagents for substituting termini of oligonucleotides |
| 04/05/1989 | EP0310229A1 Selective amplification of target polynucleotide sequences |
| 04/05/1989 | EP0310030A1 Cloning of DNA encoding transcription factor S-11 and utilization of the DNA |
| 04/05/1989 | EP0309862A1 Stilbene synthase gene |
| 04/05/1989 | EP0309548A1 Human tissue factor related dna segments, polypeptides and antibodies |
| 04/04/1989 | US4818692 Method and reagent compositions for determining alpha amylase using a blocked and labeled substrate |
| 04/04/1989 | US4818681 Fast and specific immobilization of nucleic acids to solid supports |
| 03/29/1989 | EP0309006A1 N-substituted-4,9-dioxa-1,12-dodecanediamines useful for preparing nucleic acid intercalators |
| 03/29/1989 | EP0270651A4 Novel deoxyribonucleoside phosphoramidites and their use for the preparation of oligonucleotides. |
| 03/28/1989 | US4816571 Genetic engineering method |
| 03/28/1989 | US4816569 Nucleotide derivative |
| 03/28/1989 | US4816397 Genetic engineering |
| 03/28/1989 | US4816389 Probe for DNA and a process for the detection of "shigellae" and entero-invasive strains of Escherichia coli |
| 03/23/1989 | WO1989002475A1 Polyaldehydic polynucleotides in use as probes, their preparation and use |
| 03/23/1989 | WO1989002439A1 Non-nucleotide linking reagents for nucleotide probes |
| 03/23/1989 | WO1989002436A1 Method for fixing and separating molecules comprising at least one natural or synthetic dna fragment |
| 03/22/1989 | EP0308378A2 Tumor necrosis factor (TNF)inhibitory protein and its purification |
| 03/22/1989 | EP0308066A2 Promotion of host defense by systemic dsRNA treatment |
| 03/22/1989 | EP0307730A2 Expression of mutarotase |
| 03/22/1989 | EP0307513A2 Pulmonary hydrophobic surfactant-associated proteins |
| 03/15/1989 | EP0307171A1 Recombinant dna expression vectors and dna compounds that encode insopenicillin n synthetase from aspergillus nidulans |
| 03/15/1989 | CN1031651A Diagnosis and treatment of double-stranded rna deficiency states |
| 03/14/1989 | US4812559 Vaccine against varicella-zoster virus |
| 03/14/1989 | US4812512 Solid phase synthesis of oligonucleotides |
| 03/14/1989 | CA1251119A1 Hybridization histochemistry |
| 03/14/1989 | CA1251016A1 Polynucleotide synthesizing apparatus |
| 03/09/1989 | WO1989001978A1 Specific dna molecular probes for bos-type male genome |
| 03/09/1989 | WO1989001946A1 Biological materials, processes for producing biological materials and for using such materials in therapy |
| 03/09/1989 | WO1989001941A1 Chemical process for obtaining labelled oligonucleotides and biological applications |
| 03/08/1989 | EP0306347A2 Diagnosis of double-stranded RNA deficiency states |
| 03/08/1989 | EP0305929A2 Membranes with bound oligonucleotides and peptides |
| 03/07/1989 | US4810643 Production of pluripotent granulocyte colony-stimulating factor |
| 03/07/1989 | US4810636 Chromogenic acridinone enzyme substrates |
| 03/01/1989 | EP0305229A1 Viral vector and recombinant DNA encoding one or more structural proteins (HA,F and/or NP) of a morbillivirus |
| 03/01/1989 | EP0305201A2 Protected biotin derivatives |
| 03/01/1989 | EP0305145A2 Methods and probes for detecting nucleic acids |
| 03/01/1989 | CN1031325A Topically active compositions of double stranded rnas |
| 02/28/1989 | US4808708 Chemical intermediates for polynucleotides |
| 02/28/1989 | US4808520 Hybridizing with nucleic acid, then with nucleoside triphosphate in presence of enzyme |
| 02/23/1989 | WO1989001481A1 Chromosome-specific nucleic acid probe for familial polyposis coli |
| 02/23/1989 | WO1989000582A3 Human granulocyte-macrophage colony stimulating factor and muteins thereof |
| 02/22/1989 | EP0304215A2 Phosphorylating reagents and method of using the same |
| 02/22/1989 | EP0303925A1 High repressible sequence for control of expression |
| 02/22/1989 | EP0216860A4 Stereoregular polynucleotide-binding polymers. |
| 02/21/1989 | US4806631 Immobilization of nucleic acids on solvolyzed nylon supports |
| 02/21/1989 | US4806546 Immobilization of nucleic acids on derivatized nylon supports |
| 02/21/1989 | US4806492 Polypeptide tumor inhibitors and antibodies thereto |
| 02/21/1989 | US4806463 Administering complementary segments of oligonucleotide necessary for reporduction or gene expression |
| 02/15/1989 | EP0303516A2 Topically active compositions of double-stranded RNAs |
| 02/15/1989 | EP0303033A2 Molecular cloning and characterization of a further gene sequence coding for human relaxin |
| 02/15/1989 | EP0303028A1 Method for preparing single chain urokinase |
| 02/15/1989 | EP0302881A1 Polynucleotide probes on solid support through photo-labile linkage |
| 02/14/1989 | CA1250099A1 Immunogens, antibodies, labeled conjugates and related derivatives for lidocaine and analogs thereof |
| 02/14/1989 | CA1249975A1 Non-radioactive biological probes |
| 02/09/1989 | WO1989001050A1 Selective amplification of target polynucleotide sequences |
| 02/09/1989 | WO1989001035A1 Process and device for purification of m-13 phage dna |
| 02/09/1989 | WO1989000854A1 Methods for increasing extracellular adenosine and for stabilizing mast cells |
| 02/09/1989 | DE3724951A1 Pharmaceutical composition containing modified deoxyribonucleic acid and its use |
| 02/08/1989 | EP0302758A1 Viral expression inhibitors |
| 02/08/1989 | EP0302456A1 New tissue plasminogen activator |
| 02/08/1989 | EP0302175A2 Modified labeled nucleotides and polynucleotides and methods of preparing, utilizing and detecting same |
| 02/07/1989 | US4803297 Alkylating intercalation compounds for nucleic acid labels; stability; medical diagnosis; immunoassay |
| 02/02/1989 | DE3724442A1 Verfahren und vorrichtung zur reinigung von m-13-phagen-dna Method and apparatus for the purification of M-13 phage DNA |
| 02/01/1989 | EP0301968A1 Human papilloma virus nucleic acid probes |