Patents
Patents for C07H 21 - Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids (89,892)
02/1989
02/01/1989EP0301961A1 Specific secretion-excretion-antigens from toxoplasma gondii, expression products therefrom, production processes therefor and their diagnostic and prophylactic applications
02/01/1989EP0301900A2 L'utilisation de riboside ou ribotide de l'AICA pour la fabrication d'un médicament contre la crise cardiaque ou l'infarctus du myocarde aux patients souffrant d'athérosclerosis.
02/01/1989EP0301899A2 Nucleic acid capture reagent
02/01/1989EP0301669A1 DNA constructs containing a Kluyveromyces alpha-factor leader sequence for directing secretion of heterologous derivatives
02/01/1989EP0301289A1 Humaner Papillomvirus Typ 41
01/1989
01/31/1989US4801542 Expression of biologically active PDGF analogs in eucaryotic cells
01/26/1989WO1989000582A2 Human granulocyte-macrophage colony stimulating factor and muteins thereof
01/26/1989WO1989000577A1 Digestion method
01/26/1989EP0227795A4 Method for performing nucleic acid hybridization assays.
01/25/1989EP0300687A2 Method of inhibiting human immunodeficiency virus
01/25/1989EP0300680A2 Doublestranded RNA correction of abnormalities in circulating immune complexes and monocyte function
01/18/1989EP0299810A1 Process for the production of polypeptides by recombinant DNA
01/18/1989EP0299782A2 Expression vectors for the production of human Granulocyte-Macrophage Colony Stimulation Factor in a mammalian cell host(18.05.92)
01/18/1989EP0299745A2 Double-stranded RNA correction of RNase L deficiency
01/18/1989EP0299552A1 A process for transforming cells
01/18/1989EP0299082A1 Antiviral agent
01/18/1989EP0298982A1 Protecting groups for organic synthesis.
01/18/1989CN1030424A Nucleic acid derivatives and process for preparing them
01/18/1989CN1030423A 核酸衍生物 Nucleic acid derivatives
01/17/1989CA1248895A1 Nucleic acid reagents, a method for their preparation and their use
01/12/1989WO1989000192A1 Production of kallikrein
01/12/1989WO1989000191A1 Novel thrombolytic proteins
01/12/1989DE3822406A1 Verfahren zur herstellung von nucleinsaeurederivaten und verfahren zur herstellung von diese enthaltenden medizinischen zusammensetzungen Process for the preparation of nucleic acid derivatives and process for preparing these medicinal compositions containing
01/12/1989DE3822405A1 Nucleinsaeurederivate Nucleic acid derivatives
01/12/1989DE3720754C1 Isolation of specific RNA and/or DNA
01/11/1989EP0298656A1 Polynucleotide probes
01/11/1989EP0298516A2 Azo dyestuff glycosides and a method for their manufacture
01/04/1989EP0297913A2 Production of Kallikrein
01/04/1989EP0297807A1 Novel prokaryotic expression and secretion system
01/04/1989EP0297291A2 Outer membrane protein F of Pseudomonas aeruginosa
01/04/1989EP0124561B1 Process for producing oligonucleoside phosphonates
01/04/1989CN1030140A Activated ribonucleic acid enzyme l used for the mark of virus infection
01/03/1989US4795828 Functionalized intermediate for the synthesis of alpha-functionalized derivatives and labeled conjugates of procaimamide and NAPA
01/03/1989US4795805 Derivative of adult T cell leukemia virus antigen peptide
01/03/1989US4795803 Adhesin antigens, antibodies and DNA fragment encoding the antigen, methods and means for diagnosis and immunization etc.
12/1988
12/29/1988WO1988010303A1 Preparation of novel protein sweeteners
12/29/1988WO1988010297A1 Cloning of mite allergens
12/29/1988WO1988010264A1 Nucleoside derivatives
12/28/1988CN88101606A Treatment of human viral infection by dsrna combined with viral inhibitors
12/27/1988US4794075 Method for locating and purifying DNA containing single base mismatches
12/27/1988US4793995 Modified (1-56) beta interferons
12/15/1988WO1988009820A1 Dna sequences, recombinant dna molecules and processes for producing lymphocyte function associated antigen-3
12/15/1988WO1988009812A1 Nucleotide sequences coding for polypeptides exercising a larvicidal effect in lepidoptera
12/15/1988WO1988009810A1 Novel amphiphilic nucleic acid conjugates
12/14/1988EP0294659A1 Human papillomavirus nucleic acid hybridization probes and methods for employing the same
12/13/1988CA1246474A1 Hybrid plasmids having a streptomycetes replicon and an escherichia coli replicon
12/07/1988EP0294349A2 A fibronectin binding protein as well as its preparation
12/07/1988EP0294196A2 Chemical capping by phosphitylation during oligonucleotide synthesis
12/07/1988EP0293514A1 The cloning and utilization of aminotransferase genes
12/07/1988EP0293443A1 Construction of synthetic dna and its use in large polypeptide synthesis
12/07/1988EP0293391A1 Cloned streptococcal genes encoding protein g and their use to construct recombinant microorganisms to produce protein g
12/06/1988US4789737 Oligonucleotide derivatives and production thereof
12/06/1988US4789636 Hybrids
12/01/1988WO1988009387A1 A method for detecting the predisposition to retinoblastoma and a method for detecting a retinoblastoma gene defect in tumors using a retinoblastoma gene probe
12/01/1988WO1988009375A1 Method for the preparation of polypeptides by dna recombinants
12/01/1988WO1988009372A1 Novel fusion proteins containing glutathione-s-transferase
12/01/1988WO1988009201A1 Process and device for separating and cleaning molecules
12/01/1988DE3717211A1 Vorrichtung und verfahren zur trennung und reinigung von molekuelen Apparatus and method for separation and purification of molecules
11/1988
11/30/1988EP0293266A2 A method for detecting the predisposition to retinoblastoma and a method for detecting a retinoblastoma gene in tumors using a retinoblastoma gene probe
11/30/1988EP0293249A1 Novel fusion protein
11/30/1988EP0292879A2 An episomal vector for the expression of selected DNA fragments coding for polypeptides in mammalian cells and methods for the production thereof
11/30/1988EP0292837A1 Polycationic buffers and method for gel electrophoresis of nucleic acids
11/30/1988EP0292803A2 Process for the production of a HMG-CoA-reductase-like protein
11/30/1988EP0292802A2 Process for the preparation of double stranded DNA
11/23/1988EP0292435A1 Zea mays plants and transgenic zea mays plants regenerated from protoplasts or protoplast-derived cells
11/23/1988EP0291686A2 Inhibitors of angiogenin
11/23/1988EP0291633A1 Use of 3'-azido-3'-deoxythymidine in the treatment or prophylaxis of human retroviral infections
11/23/1988EP0291586A2 Recombinant hepatitis B surface antigen and vaccine containing it
11/23/1988CN88102568A Method for preparing the xenogeneic albumen from streptomyces
11/22/1988US4786724 Nucleoside trichlorodimethylethyl phosphite esters
11/22/1988US4786718 Detecting human bladder cancer
11/17/1988EP0290978A1 Reaction tray for membrane hybridizations
11/17/1988EP0290583A1 -g(a) OLIGONUCLEOTIDES.
11/15/1988US4784956 Vector
11/15/1988US4784948 Production of streptococcal m protein immunogens and molecular probes
11/15/1988CA1244786A1 Synthesis of amino-derivitized oligonucleotides
11/09/1988EP0290419A2 DNA clone of human thrombomodulin
11/09/1988EP0290123A1 Genetically engineered DNA sequences, organisms comprising such sequences, and methods utilising such organisms
11/09/1988EP0289995A1 Cloning of DNA encoding human motilin precursor and expression of the precursor
11/09/1988EP0289936A2 Method for the preparation of foreign proteins in streptomyces
11/09/1988EP0289619A1 Process for synthesizing oligonucleotides and compounds for forming high-molecular protective group
11/09/1988EP0289586A1 Enhancing gamma-carboxylation of recombinant vitamin k-dependent proteins
11/09/1988CN86108803A Improved yeast strains
11/07/1988EP0275305A4 Dna sequences coding for modified factor viii:c and modified factor viii:c-like polypeptides and processes for producing these polypeptides in high yields.
11/03/1988WO1988006186A3 cDNAs ENCODING SOMATOTROPIN, EXPRESSION VECTORS AND HOSTS
11/02/1988EP0288513A1 Hybridization assay and means to be used in the assay.
11/02/1988EP0152459B1 Process for producing oligonucleotides
10/1988
10/26/1988EP0288163A2 Oligodeoxynucleotides as inhibitors of the replication of retroviruses and the expression of oncogenes
10/26/1988EP0287961A2 Process for the preparation of nucleic acids
10/26/1988EP0287820A1 Human relaxin analogues
10/26/1988EP0287576A1 Method to control and produce novel biopolymers
10/26/1988CN88102038A Desazapurine-nucleoside derivatives, process for the preparation thereof, pharmaceutical compositions containing them and the use thereof for nucleic acid sequencing and as antiviral agents
10/25/1988US4780530 Antiviral, antitumor agents
10/25/1988US4780504 Supports useful in solid phase synthesis of oligonucleotides
10/25/1988US4780405 Carbonic anhydrase inhibitor-tagged nucleic acid probes
10/19/1988EP0286958A2 Process and means for the determination of nucleic acids
10/19/1988EP0286898A2 Modified labeled nucleotides and polynucleotides and methods of preparing, utilizing and detecting same
10/18/1988US4778761 Vaccines, diagnosis
10/12/1988EP0286224A2 Treatment of human viral infection by dsRNA combined with viral inhibitors
10/12/1988EP0286028A2 Derivatives of disazapurine nucleosides, process for their preparation and their use in the sequence analysis of nucleic acids and as antiviral agents