Patents
Patents for C07H 21 - Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids (89,892)
03/1992
03/29/1992WO1992006176A1 Surface expression libraries of randomized peptides
03/29/1992CA2092803A1 Surface expression libraries of randomized peptides
03/25/1992EP0476071A1 Exonuclease-resistant oligonucleotides and methods for preparing the same
03/25/1992EP0476014A1 Very large scale immobilized polymer synthesis.
03/25/1992CN1059659A Diagnosis and treatment of viral hepatitis
03/24/1992US5098828 Immunoassay and testing
03/24/1992US5098823 Chromosome-specific nucleic acid probe for familial polyposis coli
03/22/1992CA2069096A1 Enzymatic synthesis of oligonucleotides
03/21/1992WO1992005186A1 Modified internucleoside linkages
03/21/1992CA2092002A1 Modified internucleoside linkages
03/19/1992WO1992004446A1 Cloning of chicken anaemia dna
03/19/1992WO1992004445A1 Cloning and sequencing of allergens of dermatophagoides (house dust mite)
03/19/1992WO1992004366A1 Method and apparatus for the rapid synthesis of substrate-bound or free peptides or oligonucleotides, flat material synthesized in this way and the use of such material
03/19/1992WO1992004358A1 Method and reagent for sulfurization of organophosphorous compounds
03/19/1992DE4029244A1 Prepn. of dansyl-ethoxy carbonyl chloride hydrochloride
03/18/1992EP0475443A2 Chemical synthesis of oligonucleotides
03/18/1992EP0475394A2 Rat C-type natriuretic peptide cDNA and precursor protein
03/18/1992EP0303625B1 Polypeptide competitor for immunoglobulin e
03/18/1992EP0216786B1 Purification, production and use of tumor necrosis factors
03/17/1992US5097097 Triazinylaminofluoresceins
03/17/1992CA1297437C Process for the preparation of protease inhibitors
03/17/1992CA1297432C Nucleic acid capture reagent
03/17/1992CA1297431C Process for the isolation of nucleic acids
03/17/1992CA1297430C Process for obtaining chemically defined and reproducible polydeoxyribonucleotide
03/12/1992DE4027675A1 Verfahren zur schnellen synthese von grossen zahlen traegergebundener oder freier peptide Method for the rapid synthesis of large numbers traegergebundener or free peptide
03/11/1992EP0473576A1 SHORT THERAPEUTIC dsRNA OF DEFINED STRUCTURE
03/11/1992EP0435877A4 Polynucleotides that encode the human proteoglycan peptide core of the effector cells of the immune response
03/11/1992EP0365663A4 Methods for detecting nucleic acid sequences
03/11/1992EP0205506B1 A method of transforming fungi with a vector
03/11/1992EP0200757B1 Promotion of wound healing with human epidermal growth factor prepared from recombinant dna
03/05/1992WO1992003577A1 Oligo(alpha-arabinofuranosyl nucleotides) and alpha-arabinofuranosyl precursors thereof
03/05/1992WO1992003568A1 Sugar modified oligonucleotides that detect and modulate gene expression
03/05/1992WO1992003464A1 Solid support synthesis of 3'-tailed oligonucleotides via a linking molecule
03/05/1992WO1992003456A1 Oligonucleotides for modulating the effects of cytomegalovirus infections
03/05/1992WO1992003139A1 Oligonucleotide modulation of cell adhesion
03/04/1992EP0472987A1 Antimicrobial peptides active against plant pathogens, their use and screening methods pertaining thereto
03/04/1992EP0472648A1 Crosslinking oligonucleotides
03/03/1992US5093246 Rna ribozyme polymerases, dephosphorylases, restriction endoribo-nucleases and methods
03/03/1992US5093245 Labeling by simultaneous ligation and restriction
03/03/1992US5093241 C-terminal cat fusion protein and process of preparation by recombinant dna
03/03/1992US5093232 Nucleic acid probes
03/03/1992CA1296664C Oligonucleoside alkyl or arylphosphonate derivatives capable of crosslinking with or cleaving nucleic acids
03/03/1992CA1296663C Arabinonucleic acid probes for dna/rna assays
02/1992
02/26/1992EP0472434A2 Antisense oligonucleotides complementary to the macromolecular synthesis operon of bacteria, and their uses in diagnosis and therapy
02/25/1992WO1992003461A1 Methods of synthesizing oligonucleotides with random codons
02/25/1992US5091518 Beta retinoic acid response elements compositions and assays
02/25/1992US5091374 Administering to a patient infected with human immunodeficiency virus a mismatched RNA being a complex of a polyiosinate and a polycytidylate or a copolynuceotide
02/25/1992CA1296272C Superoxide dismutase cloning and expression in microorganisms
02/25/1992CA1296242C Competitive homogeneous assay
02/20/1992WO1992002535A1 Automated system for polynucleotide synthesis and purification
02/20/1992WO1992002531A1 Novel polyamine conjugated oligonucleotides
02/20/1992WO1992002258A1 Nuclease resistant, pyrimidine modified oligonucleotides that detect and modulate gene expression
02/20/1992CA2087731A1 Novel polyamine conjugated oligonucleotides
02/19/1992EP0471338A2 Phenytoin derivatives
02/18/1992US5089603 Antigenic epitopes present on membrane-bound but not secreted iga
02/18/1992US5089408 Glutathione peroxidase gene and process for production of the gene product
02/16/1992WO1992003051A1 Inhibition of herpesviridae infection by antisense oligonucleotides
02/16/1992CA2089476A1 Inhibition of herpesviridae infection by antisense oligonucleotides
02/14/1992WO1992003452A1 Novel nucleoside analogs
02/12/1992EP0094428B1 Control of dna sequence transcription
02/11/1992US5087617 Methods and compositions for treatment of cancer using oligonucleotides
02/11/1992CA1295568C Cloning and utilization of aminotransferase genes
02/11/1992CA1295564C Recombinant plasmid inserted with herpes simplex virus gene
02/11/1992CA1295562C DNA SEQUENCES CODING FOR THE DR.beta.-CHAIN LOCUS OF THE HUMAN LYMPHOCYTE ANTIGEN COMPLEX AND POLYPEPTIDES, DIAGNOSTIC TYPING PROCESSES AND PRODUCTS RELATED THERETO
02/11/1992CA1295559C Method for labeling polynucleotide sequences
02/11/1992CA1295558C Synthesis of long chain dna
02/11/1992CA1295535C Rapid detection of nucleic acid sequences in a sample by labeling the sample
02/10/1992WO1992002641A1 Psoralen conjugated methylphosphonate oligonucleotides as therapeutic agents for chronic myelogenous leukemia
02/10/1992WO1992002532A1 Improved non-nucleotide-based linker reagents for oligomers
02/10/1992CA2089088A1 Psoralen conjugated methylphosphonate oligonucleotides as therapeutic agents for chronic myelogenous leukemia
02/10/1992CA2089087A1 Non-nucleotide-based-linker reagents for oligomers
02/07/1992WO1992002638A1 Homogeneous assay system
02/06/1992WO1992001699A1 Pt-CONTAINING COMPOUND, PROCESS FOR ITS PREPARATION, AND APPLICATION OF SUCH COMPOUNDS
02/05/1992EP0469755A1 Method producing a polynucleotide for use in single primer amplification
02/05/1992EP0469080A1 Method of inhibiting induction of latent or chronic viral infections
02/05/1992EP0469066A1 Improved amplified nucleic acid hybridization assays for hbv.
02/05/1992EP0469042A1 Novel oligodeoxynucleotides with 5'-linked chemical groups, method of production thereof and use thereof
02/04/1992WO1992002534A2 Compounds and methods for inhibiting gene expression
02/04/1992US5085983 Detection of human tumor progression and drug resistance
02/04/1992CA2088673A1 Compounds and methods for inhibiting gene expression
02/04/1992CA1295269C Polynucleotide analogs, methods for inhibiting nucleic acid polymerases and methods for inducing synthesis of interferon
01/1992
01/28/1992WO1992002533A1 Hydroxyl-protecting groups orthogonally removable by reduction and their use in the chemical synthesis of oligonucleotides
01/28/1992WO1992002528A1 Incorporation of selectably clevable and/or abasic sites into oligonucleotide chains and reagents therefor
01/28/1992WO1992002526A1 Large comb-type branched polynucleotides
01/28/1992CA2088257A1 Incorporation of selectably clevable and/or abasic sites into oligonucleotide chains and reagents therefor
01/28/1992CA2088255A1 Hydroxyl-protecting groups orthogonally removable by reduction and their use in the chemical synthesis of oligonucleotides
01/28/1992CA2087961A1 Large comb-type branched polynucleotides
01/28/1992CA1294899C Carbonic anhydrase inhibitor-tagged nucleic acid probes
01/27/1992WO1992001704A1 Oligodeoxyribonucleotides
01/27/1992CA2083485A1 Oligodeoxyribonucleotide
01/23/1992WO1992001047A1 Methods for producing members of specific binding pairs
01/23/1992WO1992000990A1 Interleukin receptor expression inhibiting antisense oligonucleotides
01/23/1992WO1992000989A1 Non-isotopic nucleic acid labelling method
01/23/1992WO1991013902A3 Site-specific functionalization of oligodeoxynucleotides for non-radioactive labelling
01/22/1992EP0467349A1 Regulation of gene expression by employing translational inhibition utilizing mRNA interfering complementary RNA
01/22/1992EP0466816A1 Method for enhancing transmembrane transport of exogenous molecules
01/22/1992EP0418320A4 Sequencing dna; a modification of the polymerase chain reaction
01/21/1992US5082934 Coumarin derivatives for use as nucleotide crosslinking reagents
01/21/1992US5082830 End labeled nucleotide probe
01/21/1992US5082780 Oligonucleotide-enzyme conjugate that can be used as a probe in hybridization assays and polymerase chain reaction procedures