Patents
Patents for C07H 21 - Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids (89,892)
09/1989
09/06/1989EP0144386B1 Novel preparation of nucleoside phosphoramidite intermediates
09/05/1989US4863855 Novel cloning vehicles for polypeptide expression in microbial hosts
08/1989
08/30/1989EP0330396A2 DNA sequences, recombinant DNA molecules and processes for producing lipocortins III, IV, V & VI
08/30/1989EP0330221A2 End labeled nuceotide probe
08/30/1989EP0330051A1 Human cytomegalovirus structural phosphoprotein (pp28), its preparation and use
08/30/1989CN1035126A Gene fragment coding for rabies virus glycoprotein and process for preparing rabies virus glycoprotein using the same
08/30/1989CN1035050A Double chain rna correction circulation immunity compound and mononuclear cell function disorder
08/29/1989US4861710 Recombinant DNA clone encoding laminin receptor
08/24/1989WO1989007606A1 Partly single-stranded and partly double-stranded nucleic acid probe and process for producing it
08/24/1989WO1989007603A1 Nucleic acid isolation
08/24/1989DE3804243A1 Teils einzel- und teils doppelstraengige nukleinsaeuresonde und verfahren zu ihrer herstellung Single- and double-stranded portion partly nukleinsaeuresonde and process for their production
08/23/1989EP0329311A1 Detection of mutations in nucleic acids
08/23/1989EP0329203A1 Yeast expression systems with vectors having PyK promoters, and synthesis of foreign protein
08/23/1989EP0329198A2 Ribose- and 2-deoxyribose compounds
08/22/1989US4859768 Derivatives of 2', 5'-oligoadenylate and antiviral uses thereof
08/22/1989US4859609 Binding ligand to polypeptide
08/22/1989US4859587 Recombinant herpes simplex viruses, vaccines and methods
08/22/1989CA1258673A1 Enzymic method of detecting analytes and novel substrates therefor
08/22/1989CA1258623A1 Probe containing a modified nucleic acid, recognizable by specific antibodies and use of this probe and these specific antibodies to detect and characterize a homologous dna sequence
08/17/1989DE3744785A1 Use of retrograde mirror-image antisense nucleic acids against cancers
08/15/1989US4857455 Water soluble activated capped aromatic fluorescent compounds
08/15/1989CA1258437A1 Gene for lignin degradation and uses therefor
08/09/1989EP0327429A2 Labeling by simultaneous ligation and restriction
08/09/1989EP0327391A2 Polypeptide possessing isoamylase activity, and its uses
08/09/1989EP0327360A2 Novel polypeptides and DNA encoding said polypeptides
08/08/1989US4855238 Recombinant gamma interferons having enhanced stability and methods therefor
08/08/1989US4855237 Double-stranded DNA having sequences complementary to a single-stranded DNA and derived from a bean golden mosaic virus
08/08/1989US4855231 Regulatory region for heterologous gene expression in yeast
08/08/1989US4855225 Method of detecting electrophoretically separated oligonucleotides
08/02/1989EP0325970A1 Carrier for the enzymatic or chemical and enzymatic solid phase synthesis of nucleic acids or fragments thereof
08/02/1989EP0325763A1 Apparatus and method for amplification of nucleic acids
07/1989
07/27/1989WO1989006704A1 Oligonucleotide probes for detection of periodontal pathogens
07/27/1989WO1989006702A1 Selective inhibition of gene expression by photoactivatable oligonucleotides
07/27/1989WO1989006701A1 Thiol-reactive oligonucleotide intermediates and processes for conjugation of oligonucleotides with enzymes
07/27/1989WO1989006698A1 Process for detecting nucleic acids
07/27/1989DE3902157A1 Amphiregulin, verfahren zu dessen herstellung und pharmazeutische mittel Amphiregulin, process for its preparation and pharmaceutical compositions
07/26/1989EP0325032A1 Method for separating nucleic acid
07/26/1989EP0324789A1 Methods of regulating metabolic stability of proteins
07/26/1989EP0221108A4 Process and nucleic acid construct for producing reagent complexes useful in determining target nucleotide sequences.
07/25/1989US4851390 Nutritional methods utilizing compositions containing RNA, CA+2, Mg+2 and/or ascorbate
07/25/1989US4851330 Method for detection, identification and quantitation of non-viral organisms
07/19/1989EP0324616A2 Template-directed photoligation
07/19/1989EP0324474A1 Method for the detection of nucleic acids
07/19/1989EP0324468A2 A highly specific method for detecting nucleic acids in solution
07/19/1989EP0324162A1 Method of producing antibodies by genetic engineering
07/19/1989EP0324157A1 Gene fragment coding for a rabies virus glycoprotein and process for producing a rabies virus glycoprotein using the same
07/18/1989US4849513 Deoxyribonucleoside phosphoramidites in which an aliphatic amino group is attached to the sugar ring and their use for the preparation of oligonucleotides containing aliphatic amino groups
07/18/1989US4849351 Multiple reading frame Escherichia coli expression vectors
07/18/1989US4849336 Oligonucleotide derivatives and production thereof
07/12/1989EP0323489A1 Preparation of novel protein sweeteners
07/12/1989CN1033838A Ribozymes
07/11/1989US4847165 Ribonucleic acid recovery
07/05/1989EP0323152A2 Method of synthesizing oligonucleotides
07/05/1989EP0323149A2 Vectors and compounds for expression of zymogen forms of human protein C
07/05/1989EP0322677A2 Carrier for DNA-hybridization
07/05/1989EP0322533A1 Bordetella pertussis toxin with altered toxicity
07/04/1989US4845205 2,N6 -disubstituted and 2,N6 -trisubstituted adenosine-3'-phosphoramidites
07/04/1989US4844884 Cosmetic sunscreen product for the face and body
06/1989
06/29/1989WO1989005857A1 A METHOD OF SIMULTANEOUSLY PRODUCING A LARGE NUMBER OF Leu17-VIP-ANALOGS AND NEW Leu17-VIP-ANALOGS
06/29/1989WO1989005853A1 Nucleic acid chelate conjugate as therapeutic and diagnostic agents
06/29/1989WO1989005852A1 Ribozymes
06/29/1989WO1989005816A1 Cellular toxic conjugates
06/28/1989EP0321548A1 Novel amphiphilic nucleic acid conjugates
06/27/1989US4842996 Probes comprising modified adenine groups, their preparation and their uses
06/22/1989DE3742049A1 Preparation and use of vaccines and diagnostic aids for viral diseases and cancers
06/21/1989EP0321201A2 Ribozymes
06/21/1989EP0320807A2 Novel polynucleotide analogs, methods for inhibiting nucleic acid polymerases and methods for inducing synthesis of interferon
06/21/1989EP0293391A4 Cloned streptococcal genes encoding protein g and their use to construct recombinant microorganisms to produce protein g.
06/21/1989EP0195277B1 Phosphorylation process and agent therefor
06/20/1989US4840896 Human fertility hormones rna encoding by vectors
06/15/1989WO1989005358A1 Dna and rna molecules stabilized by modifications of the 3'-terminal phosphodiester linkage and their use as nucleic acid probes and as therapeutic agents to block the expression of specifically targeted genes
06/14/1989EP0320495A1 Retrovirus of the type HIV-2 capable of inducing AIDS, and the antigenic and nucleic acid components thereof
06/14/1989EP0320103A2 Compounds for DNA deletion and oligomers used therefor as well as a method for use thereof
06/07/1989EP0319312A2 Vectors and compounds for direct expression of activated human protein C
06/07/1989EP0318703A1 Production of the anticoagulant protein PP4 by genetic engineering
06/07/1989CN1033289A Preparation of monostrepurokinase
06/06/1989US4837312 Nucleic acid probes
06/01/1989WO1989004675A1 Selective removal of immune complexes
06/01/1989WO1989004669A1 Nanbv diagnostics and vaccines
05/1989
05/31/1989EP0318451A2 DNA clone of human tissue factor inhibitor
05/31/1989EP0318296A2 Interleukin-1 receptors
05/31/1989EP0318281A2 Use of dsRNA in the prevention of viral escape
05/31/1989EP0318216A1 NANBV diagnostics and vaccines
05/30/1989US4835263 Novel compounds containing an oligonucleotide sequence bonded to an intercalating agent, a process for their synthesis and their use
05/30/1989CA1254887A1 2'-deoxy-3'-phosphonylmethyl nucleosides
05/24/1989EP0317509A2 Targetted incorporation of genes into a plant genome
05/24/1989EP0317239A2 Method and device for improved restriction fragment length polymorphism analysis
05/24/1989EP0316695A1 Recombinant HIV-2 polypeptides
05/24/1989EP0316558A1 Factor IX DNA
05/24/1989EP0169775B1 Oligonucleotides, process for their preparation and their uses as mediators in the enhancement of the effects of interferons
05/23/1989US4833251 Fluorescent compounds
05/23/1989US4833129 Hypocholesterolemically and/or hypotriglyceridemically active RNA fractions
05/23/1989US4833084 Hybridomas, genetic engineering
05/23/1989US4832959 Preparation of polypeptides having human γ-interferon activity
05/23/1989CA1254527A1 Expression vectors for enhanced production of polypeptides, plasmids containing the vectors, hosts containing the plasmids, products manufactured thereby and related methods
05/23/1989CA1254525A1 Kit for terminally chemically labeling dna
05/18/1989WO1989004375A1 Lanthanide chelate-tagged nucleic acid probes
05/18/1989WO1989004302A1 Electrochemiluminescent rhenium moieties and methods
05/17/1989EP0316016A2 Modified oligonucleotides
05/17/1989EP0315683A1 Dna sequences, recombinant dna molecules and processes for producing lymphocyte function associated antigen-3