Patents
Patents for C07H 21 - Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids (89,892)
08/1990
08/09/1990WO1990008838A1 Labeling of nucleic acids with fluorescent markers
08/09/1990WO1990008828A2 Molecular methods of hybrid seed production
08/09/1990WO1990008771A1 Dna encoding a growth factor specific for epithelial cells
08/08/1990EP0380559A1 Oligonucleotide functionalizing reagents and methods.
08/08/1990EP0174525B1 Process for the purification of synthetic oligonucleotides
08/07/1990US4946952 Process for isolating nucleic acids
08/07/1990CA1272456A1 Vaccine against varicella-zoster virus
08/01/1990WO1990008819A1 Vaccine for the preventative treatment of infection of liver fluke in ruminants
08/01/1990EP0379548A1 Determining dna sequences by mass spectrometry
08/01/1990EP0158201B1 Hybrid plasmid containing a streptomyces and an escherichia coli replicon
08/01/1990CA2045663A1 Vaccine for the preventative treatment of infection of liver fluke in ruminants
07/1990
07/31/1990US4945047 Microbiological process for the preparation of a protein by culturing a mutant bacterial strain
07/31/1990CA1272142A1 Mammalian promoters useful in yeast expression
07/26/1990WO1990008775A1 POLYPEPTIDES HAVING A HUMAN β ADRENERGIC RECEPTOR ACTIVITY, AND PLAYING A ROLE IN LIPOLYTIC RESPONSE, NUCLEIC ACIDS CODING FOR THESE POLYPEPTIDES AND USE OF SAID POLYPEPTIDES FOR SCREENING SUBSTANCES WHICH ACT ON THESE POLYPEPTIDES
07/26/1990WO1990008156A1 Derivatives of polyhydroxylated molecules for introducing at least one ramification in an oligonucleotide
07/26/1990WO1990008153A1 Reagents for the preparation of 5'-biotinylated oligonucleotides
07/25/1990EP0379369A2 Nucleic acid amplification using single primer
07/25/1990EP0378924A2 Detection of neurological disease or dysfunction
07/25/1990EP0378666A1 Interleukin ii analogs
07/25/1990EP0378652A1 Oligonucleotide hybridization probes and means for the synthesis of the most preferred probes
07/25/1990EP0378615A1 Nucleoside and polynucleotide thiophosphoramidite and phosphorodithioate compounds and processes
07/21/1990CA2008244A1 A signal peptide for the secretion of peptides in escherichia coli, a process for obtaining it and its use
07/19/1990CA2008096A1 Nucleic acid amplification using single primer
07/18/1990EP0377624A1 Specific dna molecular probes for bos-type male genome
07/18/1990EP0377573A1 Digestion method
07/12/1990WO1990008528A1 Biologically active synthetic thyrotropin and cloned gene for producing same
07/12/1990WO1990007572A1 HUMAN DNase
07/12/1990WO1990007321A2 Lymphocyte receptor homing sequences and their uses
07/12/1990CA2045131A1 Biologically active synthetic thyrotropin and cloned gene for producing same
07/11/1990EP0376968A1 Chromosome-specific nucleic acid probe for familial polyposis coli.
07/11/1990CN1043741A Novel receptor: their identification, characterization, preparation and use
07/10/1990CA2007431A1 Labeling of nucleic acids with fluorescent markers
07/09/1990EP0221173A4 Diagnostic reagents based on unique sequences within the variable region of the t cell receptor and uses thereof.
07/06/1990WO1990007582A1 End-attachment of oligonucleotides to polyacrylamide solid supports for capture and detection of nucleic acids
07/06/1990CA2044173A1 End-attachment of oligonucleotides to polyacrylamide solid supports for capture and detection of nucleic acids
07/04/1990EP0376156A2 New insulin derivatives, process for their preparation, their use and pharmaceutical compositions containing them
07/04/1990EP0375722A1 Chemical process for obtaining labelled oligonucleotides and biological applications
07/03/1990CA2006880A1 Push column and chromatography method
07/03/1990CA1271149A1 Human tpa production using vectors coding for dhfr protein
06/1990
06/28/1990WO1990006993A1 Method of detecting neurological disease or dysfunction
06/28/1990WO1990006950A1 Recombinant dna molecules, hosts, processes and human somatomedin carrier protein-like polypeptides
06/28/1990WO1990006936A1 Sequential peptide and oligonucleotide synthesis using immunoaffinity techniques
06/28/1990WO1990006934A1 Triple stranded nucleic acid and methods of use
06/28/1990WO1989012380A3 Therapeutic uses of 2',5'-oligoadenylate derivatives
06/28/1990DE3841565A1 Method for sequencing nucleic acids
06/27/1990EP0375438A2 Recombinant DNA molecules, hosts, processes and human somatomedin carrier protein-like polypeptides
06/27/1990EP0375408A1 Method for making synthetic oligonucleotides which bind specifically to target sites on duplex DNA molecules, by forming a colinear triplex, the synthetic oligonucleotides and methods of use
06/27/1990EP0375278A2 Automated system for polynucleotide synthesis and purification
06/27/1990EP0374869A1 Recombinant DNA molecules and their method of production
06/27/1990EP0374665A2 Assay of sequences using amplified genes
06/23/1990CA2004326A1 Assay of sequences using amplified genes
06/21/1990CA2006334A1 Sequential peptide and oligonucleotide syntheses using immunoaffinity techniques
06/21/1990CA2005927A1 Method of preparing nucleotide probes using a bridging complement
06/20/1990EP0373956A2 Nucleotide probes
06/20/1990EP0373335A2 Serine protease inhibitor proteins, medicaments containing them, DNA sequences coding for these proteins and methods for producing these proteins, medicaments and DNA sequences
06/19/1990US4935496 Mouse-human chimaeric immunoglobulin heavy chain specific for the call antigen
06/19/1990US4935342 Method of isolating and purifying nucleic acids from biological samples
06/19/1990US4935233 Covalently linked polypeptide cell modulators
06/19/1990CA1270453A1 Shuttle vector
06/16/1990CA2005720A1 .alpha.-plasmin inhibitor analogue and a highly productive plasmid for expression of .alpha.-plasmin inhibitor
06/16/1990CA2005557A1 Chemical preparation of high specific activity nucleotide probes
06/14/1990WO1990006373A1 Method for polymerase activity determination
06/14/1990WO1990006320A1 Substrate for polymerase activity determination
06/14/1990WO1990006318A1 Novel receptors: their identification, characterization, preparation and use
06/14/1990WO1990006044A2 PROCESS FOR PRODUCING cDNA
06/14/1990WO1990006043A2 In vitro mutagenesis
06/13/1990EP0372002A1 A covalent oligonucleotide-horseradish peroxidase conjugate
06/13/1990CN1008377B Bacterial enzymes
06/13/1990CA2002047A1 Serineprotease inhibitor proteins, pharmaceutical compositions containing them, dna sequences coding for these proteins and processes for the preparation of these proteins, pharmaceutical compositions and dna sequences
06/12/1990US4933280 Treatment of respiratory deficiency syndrome
06/12/1990CA1270217A1 Recombinant plasmid provided with hepatitis b virus gene, yeast transformed with said recombinant plasmid, and production of hepatitis b virus surface antigen
06/06/1990EP0371820A2 Novel receptors: their identification, characterization, preparation and use
05/1990
05/31/1990WO1990005732A1 Mixed ligand complexes and uses thereof as binding agents and probres to dna
05/31/1990CA2004339A1 Novel receptors: their identification, characterization, preparation and use
05/30/1990EP0370052A1 Human granulocyte-macrophage colony stimulating factor and muteins thereof
05/30/1990CN1008145B Lyophilized hepatitis b vaccine
05/29/1990US4929554 Human immune interferon
05/23/1990EP0369775A2 Compositions and process for amplifying and detecting nucleic acid sequences
05/23/1990EP0369413A2 Interferon-gamma binding proteins
05/23/1990EP0369360A2 Differentiation of nucleic acid segments on the basis of nucleotide differences
05/22/1990US4927755 Polynucelotide phosphorylase purification
05/21/1990CA2003502A1 Vitro mutagenesis
05/18/1990CA2001110A1 Compositions and process for amplifying and detecting nucleic acid sequences
05/17/1990WO1990005301A1 Electrochemiluminescent assays
05/17/1990WO1990005183A1 Interleukin-4 receptors
05/17/1990WO1990005177A1 Functional recombinantly prepared synthetic protein polymer
05/16/1990EP0368367A1 Purification, production and use of tumor necrosis factors
05/16/1990EP0368342A2 Process for producing and use of a DNA to increase the productivity in the expression of recombinant genes
05/15/1990US4925937 Diazapyrene compounds useful for photocleavage of nucleic acids
05/15/1990US4925793 Human immune interferon
05/15/1990US4924624 2,',5'-phosphorothioate oligoadenylates and plant antiviral uses thereof
05/15/1990CA2003038A1 Differentiation of nucleic acid segments on the basis of nucleotide differences
05/14/1990EP0265519A4 Electrochemiluminescent assays.
05/09/1990EP0367666A1 Specific nucleic-acid fragments of the human villin gene and their application to diagnostic ends
05/09/1990EP0367644A1 Nucleotide sequence codings for a protein with urea reactivity
05/09/1990EP0367566A1 Interleukin-4 receptors
05/09/1990EP0366685A1 Nucleoside derivatives.
05/08/1990US4923978 Process for purifying nucleic acids
05/08/1990US4923901 Membranes with bound oligonucleotides and peptides
05/08/1990US4923805 Culturing cells capable of glycosylating proteins; gene expression dimerization