Patents
Patents for C07H 21 - Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids (89,892)
04/1993
04/15/1993WO1993007295A1 Formation of triple helix complexes of single stranded nucleic acids using nucleoside oligomers
04/15/1993WO1993007293A1 Detecting digeorge syndrome mutations
04/15/1993WO1993007278A1 Synthetic dna sequence having enhanced insecticidal activity in maize
04/15/1993WO1993007166A1 Polymorphic locus
04/15/1993WO1993007164A1 Process for rna synthesis using a new deprotection reagent
04/15/1993WO1993006712A1 Production of gamma linolenic acid by a δ6-desaturase
04/15/1993CA2120525A1 Polymorphic locus
04/15/1993CA2119890A1 Formation of triple helix complexes of single stranded nucleic acids using nucleoside oligomers
04/14/1993EP0536330A1 Glyphosate tolerant plants
04/13/1993US5202419 Anticoagulative protein pp4-x
04/13/1993CA1316132C Cdna and gene for human angiogenin (angiogenesis factor) and method of expression
04/11/1993CA2080309A1 Mutations in ryanodine receptor causative of human malignant hyperthermia
04/07/1993EP0535119A1 A novel vector to produce biologically important peptides
04/07/1993EP0458876B1 Method of separating oligonucleotides from a mixture
04/07/1993EP0290583B1 $g(a) OLIGONUCLEOTIDES
04/06/1993US5200183 Recombinant bile salt activated lipases
04/06/1993CA1315717C Nucleic acid derivatives
04/01/1993WO1993006246A1 Production of chromosome region specific dna sequences and transamination
04/01/1993WO1993006123A1 Human cyclin e
04/01/1993WO1993006122A1 Duplex-forming, polynucleotide conjugates
04/01/1993WO1993006121A1 Method of synthesizing diverse collections of oligomers
04/01/1993WO1993001286A3 Localized oligonucleotide therapy
04/01/1993DE4227882A1 Funktionalisierte traegermaterialien fuer gleichzeitige synthese und direktmarkierung von oligonukleotiden als primer fuer matrizenabhaengige enzymatische nukleinsaeuresynthesen Functionalized traegermaterialien for simultaneous synthesis and direct labeling of oligonucleotides as primers for enzymatic template-nukleinsaeuresynthesen
04/01/1993CA2119927A1 Duplex-forming polynucleotide conjugates
04/01/1993CA2118806A1 Method of synthesizing diverse collections of oligomers
03/1993
03/31/1993EP0534097A2 Use of NADH or NADPH against cancer or AIDS
03/31/1993EP0533906A1 Detection of dna/rna by fluorescence polarization
03/31/1993EP0533854A1 Pcr primers for detection of legionella species and methods for controlling visual intensity in hybridization assays
03/31/1993EP0533838A1 Nucleic acid ligands
03/31/1993EP0470976B1 Processes and compositions for the isolation of human relaxin
03/31/1993EP0281604B1 Single polypeptide chain binding molecules
03/31/1993CN1020194C Method for preparation of difluorated nucleoside derivant
03/30/1993US5198540 Process for the preparation of oligonucleotides in solution
03/30/1993CA1315223C Method for mutagenesis by oligonucleotide-directed repair of a strand break
03/30/1993CA1315222C Polynucleotide probes and a method for their preparation
03/27/1993CA2078905A1 Process for the specific amplification of nucleic acid sequences
03/24/1993EP0510085A4 Dna-dependent rna polymerase transcripts as reporter molecules for signal amplification in nucleic acid hybridization assays
03/24/1993EP0211894B1 Fsh
03/24/1993EP0180603B1 Rotavirus
03/24/1993CA2078801A1 Enzymatically inactive phospholipase d of corynebacterium pseudotuberculosis
03/23/1993US5196319 Primary biliary cirrhosis autoantigen
03/23/1993CA1314794C Assay for nucleic acid sequence in a sample
03/18/1993WO1993005180A1 Formation of triple helix complexes of double stranded dna using nucleoside oligomers which comprise purine base analogs
03/18/1993WO1993005176A1 Improvements in oligonucleotide primers and probes
03/18/1993WO1993005175A1 Improvements in oligonucleotide primers and probes
03/18/1993WO1993005150A1 Collagen-induced platelet aggregation inhibitor
03/18/1993WO1993005071A1 INTERLEUKIN 1β PROTEASE AND INTERLEUKIN 1β PROTEASE INHIBITORS
03/18/1993WO1993005062A1 SYNTHETIC tRNAs
03/18/1993WO1993005060A1 Functionalized carrier materials for the simultaneous synthesis and direct labeling of oligonucleotides as primers for the matrix-dependant, enzymatic synthesis of nucleic acids
03/18/1993WO1993004701A1 Targeted delivery of poly- or oligonucleotides to cells
03/18/1993CA2117174A1 Collagen-induced platelet aggregation inhibitor
03/18/1993CA2116343A1 Formation of triple helix complexes of double stranded dna using nucleoside oligomers which comprise purine base analogs
03/18/1993CA2116107A1 Targeted delivery of poly-or oligonucleotides to cells
03/17/1993EP0531798A2 Method for detecting, identifying, and quantitating organisms and viruses
03/17/1993EP0531447A1 Compositions and methods for modulating rna activity through modification of the 5' cap structure of rna
03/17/1993EP0531436A1 Sequence-specific nonphotoactivated crosslinking agents which bind to the major groove of duplex dna
03/17/1993EP0531365A1 Diagnosis and treatment of viral hepatitis
03/16/1993US5194428 Inhibition of influenza virus replication by oligonucleotide phosphorothioates
03/16/1993CA1314505C Chimeric gene for herbicidal resistance
03/10/1993EP0531027A1 Labelled primers for nucleic acid probes
03/10/1993EP0530937A1 Collagen-induced platelet aggregation inhibitor
03/10/1993EP0530794A1 Method for detecting nucleic acids which are similar to one another
03/10/1993EP0530614A1 Novel antisense oligonucleotider with continuous phosphoramidate internucleotide linkage
03/10/1993EP0530243A1 Polynucleotide amplification
03/10/1993EP0525181A4 Novel lanthanide chelate-conjugated oligonucleotides
03/10/1993EP0364490B1 A method for detecting a retinoblastoma gene defect in tumors using a retinoblastoma gene probe
03/10/1993CA2077709A1 Oligonucleotides and determination system of hcv genotypes
03/09/1993US5192658 DNA polymorphism
03/04/1993WO1993004373A1 Calcium receptor active molecules
03/04/1993WO1993004204A1 Synthetic unrandomization of oligomer fragments
03/04/1993WO1993004198A1 Oligonucleotides and their use in an assay for encephalopathies
03/04/1993WO1993003770A1 Method and compositions for cellular reprogramming
03/04/1993WO1993003736A1 Cross-linking oligonucleotides for enzyme-mediated triple strand formation
03/04/1993WO1993003733A1 Syntheses, pharmaceutical composition and method of application of (2'-5') oligoadenylate analogues
03/04/1993CA2115829A1 Oligonucleotides and their use in an assay for encephalopathies
03/04/1993CA2077314A1 Antisense oligonucleotides with phosphoramidate internucleotide linkage throughout
03/03/1993EP0529573A1 Solid-phase synthesizer
03/03/1993EP0529088A1 NOVEL PLASMID pBUL1 DERIVED FROM LACTOBACILLUS AND DERIVATIVE THEREOF
03/03/1993EP0529008A1 Modulation of gene expression through interference with rna secondary structure
03/03/1993EP0528870A1 Protein-nucleic acid probes and immunoassays using same
03/03/1993EP0495919A4 Protection from shock subsequent to injury by double-stranded rnas
03/03/1993EP0371067B1 Process and device for purification of m-13 phage dna
03/02/1993US5190931 Regulation of gene expression by employing translational inhibition of MRNA utilizing interfering complementary MRNA
03/02/1993CA1314009C Acridinium ester labeling and purification of nucleotide probes
02/1993
02/24/1993EP0528306A2 Mycobacterium primers and probes
02/24/1993EP0527906A1 Inhibition of influenza virus replication by oligonucleotides
02/24/1993CA2049750A1 Method of separating oligonucleotides from a mixture
02/23/1993US5188934 Long wavelength, narrow emission bandwidth fluorescent dyes; automatic DNA sequencing
02/23/1993US5188897 Viricides, metabolic stability
02/23/1993CA1313831C Method of generating desired aminoterminal residues in proteins and methods of regulating metabolic stability of proteins
02/18/1993WO1993003167A1 Method of isolation of dna
02/18/1993CA2115061A1 Method of isolation of dna
02/17/1993EP0527433A1 Novel fluorescent label
02/17/1993EP0527184A1 Phosphoramidite derivatives, their preparation and the use thereof in the incorporation of reporter groups on synthetic oligonucleotides.
02/17/1993EP0514488A4 Retinoid receptor compositions and methods
02/10/1993EP0526953A1 Multichain polypeptides or proteins and processes for their production
02/10/1993EP0526912A2 Methods and compositions for the detection of a single-stranded target genetic material
02/09/1993US5185444 Uncharged morpolino-based polymers having phosphorous containing chiral intersubunit linkages
02/09/1993US5185439 Acridinium ester labelling and purification of nucleotide probes
02/09/1993US5185243 Hybridizing two nucleotide sequences with a target nucleotide, covalently attaching two nucleotide sequences and determining the presence of covalently attached nucleotide sequences