Patents
Patents for C07H 21 - Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids (89,892)
06/1993
06/10/1993CA2122470A1 Oligonucleotides having aminohydrocarbon phosphonate moieties
06/10/1993CA2083416A1 Oligodeoxyribonucleotides having anti-ischemic activity and methods of preparation thereof
06/09/1993EP0545010A1 Method for the specific amplification of nucleic acid sequences
06/09/1993EP0544809A1 Methods of synthesizing oligonucleotides with random codons
06/09/1993EP0544792A1 Novel nucleoside analogs
06/09/1993EP0544716A1 Oligonucleotide modulation of cell adhesion
06/09/1993EP0478708A4 Formation of triple helix complexes of double stranded dna using nucleoside oligomers
06/09/1993EP0358657B1 Poly(deoxyribonucleotides), pharmaceutical compositions, use and preparation of the poly(deoxyribonucleotides)
06/09/1993EP0134242B1 Protective peptide antigen
06/08/1993US5218105 3'-Phosphoramidating a 5'-aldehydic-protected nucleoside; forming a 5'-Schiff Base by reaction with a polyamine and reducing; reacting with a phosphorothioated oligonucleotide
06/08/1993US5218103 Nucleoside thiophosphoramidites
06/08/1993US5218102 Nucleic acid probe containing a terminal carbamyl linking non-radioactive labeling and preparating processes
06/08/1993US5218101 Leader sequence inducing a post-translational modification of polypeptides in bacteria, and gene therefor
06/08/1993US5218100 Dna encoding for the precursor protein of apc polypeptide associated with alzheimer's disease
06/08/1993US5218088 Process for preparing dithiophosphate oligonucleotide analogs via nucleoside thiophosphoramidite intermediates
06/08/1993US5217867 Measuring genetic transcription induced by steroid hormone receptors bound to DNA segments for use in screening assays
06/08/1993US5217866 Polynucleotide assay reagent and method
06/08/1993CA1318867C Plasmid expression vector for use in escherichia coli
06/02/1993EP0544293A2 Process for the preparation of biologically active NGF by genetic engineering
06/02/1993EP0543942A1 Homogeneous assay system
06/02/1993EP0543913A1 Oligo(alpha-arabinofuranosyl nucleotides) and alpha-arabinofuranosyl precursors thereof
06/02/1993EP0543906A1 Hydroxyl-protecting groups orthogonally removable by reduction and their use in the chemical synthesis of oligonucleotides.
06/02/1993EP0543889A1 Incorporation of selectably clevable and/or abasic sites into oligonucleotide chains and reagents therefor
06/02/1993EP0422090B1 Derivatives of nucleosides which may be used for the synthesis of marked oligonucleotides, and oligonucleotides obtained from these derivatives and their synthesis
06/02/1993CN1072722A Production of gamma linolenic acid by delta 6 -desaturase.
06/01/1993US5216141 Oligonucleotide analogs containing sulfur linkages
06/01/1993US5215895 Dna encoding a mammalian cytokine, interleukin-11
06/01/1993US5215882 Reacting an amine-containing nucleotide-terminating strand of DNA or RNA and an oxidized cellulose containing aldehyde groups in the presence of a reducing agent; kits
06/01/1993CA1318654C Chromatographic supports for separation of oligonucleotides
06/01/1993CA1318619C Method of using eukaryotic expression vectors comprising the bk virus enhancer
05/1993
05/27/1993WO1993010267A1 Rapid assays for amplification products
05/27/1993WO1993010264A1 Restriction amplification assay
05/27/1993WO1993010242A1 NOVEL HUMAN cdc25 GENES, ENCODED PRODUCTS AND USES THEREFOR
05/27/1993WO1993010161A1 Polymer reversal on solid surfaces
05/27/1993WO1993010140A1 Oligonucleotides having modified anionic moieties
05/27/1993WO1993010138A1 Anti-sense oligonucleotides for isotype-specific suppression of immunoglobulin production
05/27/1993WO1993009815A1 Specific tolerance in transplantation
05/27/1993WO1993009789A1 Treatment of melanoma with antisense oligonucleotides to c-myb proto-oncogene
05/27/1993WO1993009668A1 Combinatorial strategies for polymer synthesis
05/27/1993CA2389355A1 Combinatorial strategies for polymer synthesis
05/27/1993CA2123611A1 Treatment of melanoma with antisense oligonucleotides to c-myb proto-oncogene
05/27/1993CA2122734A1 Restriction amplification assay
05/27/1993CA2122132A1 Anti-sense oligonucleotides for isotype-specific suppression of immunoglobulin production
05/26/1993EP0543004A1 Purine base modified 2'-deoxyribonucleosides, use in triplex forming oligonucleotides and process for preparing the same
05/26/1993EP0542928A1 Improved non-nucleotide-based linker reagents for oligomers
05/26/1993EP0542887A1 Psoralen conjugated methylphosphonate oligonucleotides as therapeutic agents for chronic myelogenous leukemia
05/26/1993EP0542770A1 Random bio-oligomer library, a method of synthesis thereof, and a method of use thereof
05/26/1993EP0477296A4 Prenatal bovine sex determination using male-specific oligonucleotides
05/26/1993EP0462100B1 Method for purifying nucleic acids
05/26/1993CN1020924C Production of pluripotent granule cell colony stimulating factor
05/25/1993US5214136 Anthraquinone-derivatives oligonucleotides
05/25/1993US5214135 N-protected-2'-O-methyl-ribonucleosides and N-protected 2'-O-methyl-3'-cyanoethyl-N-,N-diisopropyl phosphoramidite ribonucleosides
05/19/1993EP0541742A1 2',5'-nucleotide analogs as antiviral agents
05/19/1993EP0541722A1 Compounds and methods for inhibiting gene expression.
05/19/1993EP0541693A1 Large comb-type branched polynucleotides
05/18/1993US5212304 Amino-derivatized phosphoramidite linking agents
05/18/1993US5212295 Monomers for preparation of oligonucleotides having chiral phosphorus linkages
05/13/1993WO1993009236A1 Myogenic vector systems
05/13/1993WO1993009228A1 TGF-β TYPE RECEPTOR cDNAS AND USES THEREFOR
05/13/1993WO1993009185A1 Long wavelength chemically reactive dipyrrometheneboron difluoride dyes and conjugates
05/13/1993WO1993009141A1 Antigen associated with type i diabetes mellitus
05/13/1993WO1993009128A1 Hybridization of polynucleotides conjugated with chromophores and fluorophores to generate donor-to-donor energy transfer system
05/13/1993WO1993009127A1 Enhanced triple-helix formation directed by oligonucleotides composed of 2'-deoxy-7-deazaxanthosine and 2'-deoxy-7-deazaguanosine and related analogs
05/13/1993CA2122617A1 Myogenic vector systems
05/13/1993CA2122491A1 Tgf-.beta. type receptor cdnas and uses therefor
05/13/1993CA2122359A1 Antigen associated with type i diabetes mellitus
05/12/1993EP0541340A2 Biopolymer synthesis apparatus and method
05/12/1993EP0540997A1 Methods and reagents for HLA class I DNA typing
05/12/1993EP0540742A1 Oligodeoxyribonucleotides
05/12/1993EP0540709A1 Novel antipathogenic peptides and compositions containing same
05/12/1993CN1071955A Mycobacterium primers and probes
05/11/1993US5210264 S-(2,4-dichlorobenzyl)-β-cyanoethyl phosphorothioate diester
05/11/1993US5210203 Sulfonamide-derivative compounds for tagging nucleic acid probes
05/11/1993US5210015 Polymerase chain reaction technique
05/11/1993CA1317534C Method of enumerating escherichia coli
05/06/1993CA2081582A1 Methods and reagents for hla class i dna typing
05/05/1993EP0539515A1 Non-corrosive composition and methods useful for the extraction of nucleic acids
05/05/1993EP0539466A1 Pt-CONTAINING COMPOUND, PROCESS FOR ITS PREPARATION, AND APPLICATION OF SUCH COMPOUNDS.
05/05/1993EP0515569A4 Calcium channel compositions and methods
05/05/1993EP0211077B1 Metalloproteinase inhibitor sequence recombinant vector system for using same and recombinant-dna method for the manufacture of same
05/05/1993CN1020473C Dna clones coding for polypeptides exhibiting human graulocyte macrophage and eosinophil cellular growth factor activity
05/05/1993CN1020472C Mammalian interleukin-4
05/04/1993US5208218 T cell growth factor glycoproteins
05/04/1993US5208149 Regulating gene expression
05/04/1993US5208144 Genetic engineering and hybridization
05/04/1993CA1317207C2 Solution phase nucleic acid sandwich assay and polynucleotide probes useful therein
04/1993
04/29/1993WO1993008296A1 Oligonucleotides having chiral phosphorus linkages
04/29/1993WO1993008207A1 Novel cytokine
04/29/1993WO1993008201A1 Chromatographic separation of phosphorothioate oligonucleotides
04/29/1993WO1993007883A1 Derivatized oligonucleotides having improved uptake and other properties
04/28/1993CN1071333A Calcium receptor active molecules
04/27/1993CA1316849C Vaccinia dna
04/27/1993CA1316832C Treatment of human viral infection by dsrna combined with viral inhibitors
04/21/1993EP0538194A1 Bicyclic nucleosides, oligonucleotides, their method of preparation and intermediates therein
04/21/1993EP0537994A1 Efficient gene probe conjugations by an unconventional mixed anhydride method
04/21/1993EP0537299A1 Oligonucleotide-transport agent disulfide conjugates
04/21/1993EP0537160A1 Expression of recombinant hemoglobin in yeast
04/20/1993US5204456 Derivatives of nucleosides and their use for the synthesis of oligonucleotides
04/20/1993US5204455 Oligonucleotides having internal phosphonate linkages from a fast and efficient solid phase synthesis
04/18/1993CA2080640A1 Bicyclic nucleosides, oligonucleotides, process for their preparation and intermediates